MA54465A - Inhibiteurs de cxcr7 destinés au traitement du cancer - Google Patents
Inhibiteurs de cxcr7 destinés au traitement du cancerInfo
- Publication number
- MA54465A MA54465A MA054465A MA54465A MA54465A MA 54465 A MA54465 A MA 54465A MA 054465 A MA054465 A MA 054465A MA 54465 A MA54465 A MA 54465A MA 54465 A MA54465 A MA 54465A
- Authority
- MA
- Morocco
- Prior art keywords
- cancer
- treatment
- cxcr7
- inhibitors
- cxcr7 inhibitors
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Endocrinology (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862778605P | 2018-12-12 | 2018-12-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA54465A true MA54465A (fr) | 2021-10-20 |
Family
ID=71073777
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA054465A MA54465A (fr) | 2018-12-12 | 2019-12-11 | Inhibiteurs de cxcr7 destinés au traitement du cancer |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US11464786B2 (fr) |
| EP (1) | EP3893882B1 (fr) |
| JP (1) | JP7590084B2 (fr) |
| KR (1) | KR102897347B1 (fr) |
| CN (1) | CN113194956A (fr) |
| AU (1) | AU2019398198B2 (fr) |
| BR (1) | BR112021011222A2 (fr) |
| CA (1) | CA3122100A1 (fr) |
| IL (1) | IL283885B2 (fr) |
| MA (1) | MA54465A (fr) |
| MX (1) | MX2021006915A (fr) |
| SG (1) | SG11202105889YA (fr) |
| WO (1) | WO2020123582A1 (fr) |
| ZA (1) | ZA202103914B (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX359651B (es) | 2012-11-29 | 2018-10-05 | Chemocentryx Inc | Antagonistas de cxcr7. |
| MX2021006915A (es) * | 2018-12-12 | 2021-08-24 | Chemocentryx Inc | Inhibidores de cxcr7 para el tratamiento de cancer. |
| AU2021405511A1 (en) * | 2020-12-22 | 2023-06-22 | Luxembourg Institute Of Health (Lih) | Conolidine analogues as selective ackr3 modulators for the treatment of cancer and cardiovascular diseases |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4966691A (fr) | 1972-10-30 | 1974-06-27 | ||
| JP3989554B2 (ja) | 1996-03-29 | 2007-10-10 | デユフアー・インターナシヨナル・リサーチ・ベー・ブイ | ピペラジンおよびピペリジン化合物 |
| DE60007745T2 (de) | 1999-06-30 | 2005-03-10 | Bristol-Myers Squibb Co. | Heterocyclische aminopyrrolidon-derivate als melatonergene wirkstoffe |
| EP1301484A2 (fr) | 2000-07-20 | 2003-04-16 | Neurogen Corporation | Ligands du recepteur de la capsicine |
| ME00502B (me) | 2001-01-05 | 2011-10-10 | Amgen Fremont Inc | Antitjela za insulinu sličan receptor faktora i rasta |
| CA2448080A1 (fr) | 2001-05-22 | 2002-11-28 | Neurogen Corporation | Ligands recepteurs de l'hormone de concentration de la melanine: analogues de 1-benzyl-4-aryl piperazine substituee |
| US7169750B2 (en) | 2001-07-31 | 2007-01-30 | Anormed, Inc. | Methods to mobilize progenitor/stem cells |
| US7871619B2 (en) | 2001-11-30 | 2011-01-18 | Chemocentryx, Inc. | Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors |
| MXPA04008797A (es) | 2002-03-13 | 2004-11-26 | Janssen Pharmaceutica Nv | Inhibidores de histona desacetilasa. |
| WO2004009587A1 (fr) | 2002-07-22 | 2004-01-29 | Orchid Chemicals & Pharmaceuticals Ltd | Derives de l'oxazolidinone, agents antibacteriens |
| JP2004203871A (ja) | 2002-12-13 | 2004-07-22 | Yamanouchi Pharmaceut Co Ltd | 医薬組成物 |
| WO2005023771A1 (fr) | 2003-09-05 | 2005-03-17 | Ono Pharmaceutical Co., Ltd. | Antagoniste du recepteur de la chimiokine et son utilisation a des fins medicales |
| WO2005074535A2 (fr) | 2004-01-30 | 2005-08-18 | Eisai Co., Ltd. | Inhibiteurs de cholinesterase pour des troubles de la colonne vertebrale |
| WO2005074645A2 (fr) | 2004-02-03 | 2005-08-18 | Chemocentryx, Inc. | Procedes et compositions permettant de moduler l'angiogenese |
| AU2006230674A1 (en) | 2004-03-18 | 2006-11-16 | The Brigham And Women's Hospital, Inc. | Methods for the Treatment of Synucleinopathies |
| CA2569561C (fr) * | 2004-06-07 | 2014-08-12 | Chiron Corporation | Anticorps monoclonaux de lapin vis-a-vis des antigenes de surface de l'hepatite b et procedes d'utilisation |
| EP1637529A1 (fr) | 2004-09-20 | 2006-03-22 | 4Sc Ag | Nouveaux analogues de piperidin-4-yl-thiazole-carboxamide en tant qu'inhibiteurs de proliferation de lymphocytes T er leurs utilisations |
| US7601745B2 (en) | 2004-09-27 | 2009-10-13 | 4Sc Ag | Heterocyclic NF-kB inhibitors |
| WO2006038989A1 (fr) | 2004-09-29 | 2006-04-13 | Chemocentryx, Inc. | Arylamides substitues |
| WO2006100461A1 (fr) | 2005-03-23 | 2006-09-28 | Astrazeneca Ab | 2-azetidinyl-4-(lh-pyrazol-3-ylamino)pyrimidines en tant qu'inhibiteurs de l'activite du recepteur du facteur de croissance insulinique i |
| AU2006263657A1 (en) | 2005-06-29 | 2007-01-04 | Chemocentryx, Inc. | Substituted N-cinnamyl benzamides |
| DK1954274T3 (da) | 2005-11-10 | 2011-01-31 | Chemocentryx Inc | Substituerede quinoloner og fremgangsmåder til anvendelse |
| WO2007111275A1 (fr) | 2006-03-24 | 2007-10-04 | The University Of Tokyo | Procédé destiné à inhiber la transduction de signal, inhibiteur de transduction de signal à utiliser dans un tel procédé et utilisation correspondante |
| EP2001485B1 (fr) | 2006-03-29 | 2015-09-09 | Merck Sharp & Dohme Corp. | Antagonistes des récepteurs de l'orexine sous forme de composés diazépane |
| WO2007115231A2 (fr) | 2006-03-30 | 2007-10-11 | Chemocentryx, Inc. | Modulateurs de cxcr4 |
| WO2007115232A2 (fr) | 2006-03-30 | 2007-10-11 | Chemocentryx, Inc. | Modulateurs cxcr4 |
| US20090192143A1 (en) | 2006-07-14 | 2009-07-30 | Cox Christopher D | Substituted diazepan orexin receptor antagonists |
| BRPI0714440A2 (pt) | 2006-07-21 | 2013-04-24 | Irm Llc | composto inibidor de itpkb, uso do mesmo e composiÇço farmacÊutica |
| WO2008020229A2 (fr) | 2006-08-17 | 2008-02-21 | Astrazeneca Ab | Composés chimiques |
| US8088895B2 (en) | 2006-10-18 | 2012-01-03 | Chemocentryx, Inc. | Antibodies that bind CXCR7 epitopes |
| PE20081229A1 (es) | 2006-12-01 | 2008-08-28 | Merck & Co Inc | Antagonistas de receptor de orexina de diazepam sustituido |
| KR20090094125A (ko) | 2006-12-08 | 2009-09-03 | 엑셀리시스, 인코포레이티드 | Lxr 및 fxr 조절자 |
| AR064464A1 (es) | 2006-12-22 | 2009-04-01 | Genentech Inc | Anticuerpos anti - receptor del factor de crecimiento insulinico |
| US8404674B2 (en) * | 2007-03-07 | 2013-03-26 | Boehringer Ingelheim International Gmbh | Substituted 9H-purin-2-YL compounds, compositions thereof and uses thereof |
| US20080293711A1 (en) | 2007-03-08 | 2008-11-27 | Clark Michael P | Chemokine receptor modulators |
| TW200944523A (en) | 2008-02-08 | 2009-11-01 | Organon Nv | (Dihydro)pyrrolo[2,1-a]isoquinolines |
| CA2742515C (fr) | 2008-11-04 | 2017-07-11 | Chemocentryx, Inc. | Modulateurs 1,4-diazepane de cxcr7 |
| US8853202B2 (en) | 2008-11-04 | 2014-10-07 | Chemocentryx, Inc. | Modulators of CXCR7 |
| GB0822981D0 (en) | 2008-12-17 | 2009-01-21 | Summit Corp Plc | Compounds for treatment of duchenne muscular dystrophy |
| AU2011282776B2 (en) * | 2010-07-27 | 2014-06-12 | Boston Medical Center Corporation | Aryl hydrocarbon receptor (AhR) modifiers as novel cancer therapeutics |
| KR101541086B1 (ko) | 2010-08-20 | 2015-08-03 | 허치슨 메디파르마 리미티드 | 피롤로피리미딘 화합물 및 그 용도 |
| EP2616442B8 (fr) * | 2010-09-14 | 2018-10-17 | Exelixis, Inc. | Inhibiteurs de pi3k-delta et leurs procédés d'utilisation et fabrication |
| GB201017345D0 (en) | 2010-10-14 | 2010-11-24 | Proximagen Ltd | Receptor antagonists |
| US9150644B2 (en) | 2011-04-12 | 2015-10-06 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Human monoclonal antibodies that bind insulin-like growth factor (IGF) I and II |
| AU2012245971A1 (en) | 2011-04-21 | 2013-10-17 | Piramal Enterprises Limited | A crystalline form of a salt of a morpholino sulfonyl indole derivative and a process for its preparation |
| MX359651B (es) | 2012-11-29 | 2018-10-05 | Chemocentryx Inc | Antagonistas de cxcr7. |
| US9260527B2 (en) | 2013-03-15 | 2016-02-16 | Sdix, Llc | Anti-human CXCR4 antibodies and methods of making same |
| KR20250152679A (ko) * | 2015-04-29 | 2025-10-23 | 래디어스 파마슈티컬스, 인코포레이티드 | 암을 치료하는 방법 |
| MX2021006915A (es) * | 2018-12-12 | 2021-08-24 | Chemocentryx Inc | Inhibidores de cxcr7 para el tratamiento de cancer. |
-
2019
- 2019-12-11 MX MX2021006915A patent/MX2021006915A/es unknown
- 2019-12-11 AU AU2019398198A patent/AU2019398198B2/en active Active
- 2019-12-11 KR KR1020217021338A patent/KR102897347B1/ko active Active
- 2019-12-11 WO PCT/US2019/065600 patent/WO2020123582A1/fr not_active Ceased
- 2019-12-11 CN CN201980083136.4A patent/CN113194956A/zh active Pending
- 2019-12-11 IL IL283885A patent/IL283885B2/en unknown
- 2019-12-11 CA CA3122100A patent/CA3122100A1/fr active Pending
- 2019-12-11 JP JP2021533313A patent/JP7590084B2/ja active Active
- 2019-12-11 SG SG11202105889YA patent/SG11202105889YA/en unknown
- 2019-12-11 MA MA054465A patent/MA54465A/fr unknown
- 2019-12-11 EP EP19894634.5A patent/EP3893882B1/fr active Active
- 2019-12-11 US US16/710,160 patent/US11464786B2/en active Active
- 2019-12-11 BR BR112021011222-7A patent/BR112021011222A2/pt unknown
-
2021
- 2021-06-07 ZA ZA2021/03914A patent/ZA202103914B/en unknown
-
2022
- 2022-07-29 US US17/816,281 patent/US20230100102A1/en not_active Abandoned
-
2024
- 2024-09-13 US US18/885,326 patent/US20250090543A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020123582A1 (fr) | 2020-06-18 |
| ZA202103914B (en) | 2024-11-27 |
| CN113194956A (zh) | 2021-07-30 |
| IL283885A (en) | 2021-07-29 |
| EP3893882A4 (fr) | 2022-08-31 |
| US20200188410A1 (en) | 2020-06-18 |
| JP2022512367A (ja) | 2022-02-03 |
| CA3122100A1 (fr) | 2020-06-18 |
| AU2019398198B2 (en) | 2025-08-07 |
| EP3893882A1 (fr) | 2021-10-20 |
| EP3893882B1 (fr) | 2026-04-15 |
| KR20210102338A (ko) | 2021-08-19 |
| MX2021006915A (es) | 2021-08-24 |
| SG11202105889YA (en) | 2021-07-29 |
| US20250090543A1 (en) | 2025-03-20 |
| AU2019398198A1 (en) | 2021-07-08 |
| IL283885B2 (en) | 2026-02-01 |
| US11464786B2 (en) | 2022-10-11 |
| JP7590084B2 (ja) | 2024-11-26 |
| BR112021011222A2 (pt) | 2021-08-24 |
| IL283885B1 (en) | 2025-10-01 |
| US20230100102A1 (en) | 2023-03-30 |
| KR102897347B1 (ko) | 2025-12-05 |
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