MA54825A - Modulateurs de gpr35 - Google Patents

Modulateurs de gpr35

Info

Publication number
MA54825A
MA54825A MA054825A MA54825A MA54825A MA 54825 A MA54825 A MA 54825A MA 054825 A MA054825 A MA 054825A MA 54825 A MA54825 A MA 54825A MA 54825 A MA54825 A MA 54825A
Authority
MA
Morocco
Prior art keywords
gpr35
modulators
gpr35 modulators
Prior art date
Application number
MA054825A
Other languages
English (en)
Inventor
Robert Higuchi
Original Assignee
Prometheus Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prometheus Biosciences Inc filed Critical Prometheus Biosciences Inc
Publication of MA54825A publication Critical patent/MA54825A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
MA054825A 2019-01-24 2020-01-23 Modulateurs de gpr35 MA54825A (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962796459P 2019-01-24 2019-01-24
US201962873703P 2019-07-12 2019-07-12
US201962928223P 2019-10-30 2019-10-30

Publications (1)

Publication Number Publication Date
MA54825A true MA54825A (fr) 2021-12-01

Family

ID=71733100

Family Applications (1)

Application Number Title Priority Date Filing Date
MA054825A MA54825A (fr) 2019-01-24 2020-01-23 Modulateurs de gpr35

Country Status (13)

Country Link
US (2) US11053251B2 (fr)
EP (1) EP3914256B1 (fr)
JP (1) JP7588077B2 (fr)
KR (1) KR102863894B1 (fr)
CN (1) CN113631168B (fr)
AU (1) AU2020210930B2 (fr)
BR (1) BR112021014566A2 (fr)
CA (1) CA3127786A1 (fr)
IL (1) IL285074B2 (fr)
MA (1) MA54825A (fr)
MX (1) MX2021008941A (fr)
TW (1) TWI845600B (fr)
WO (1) WO2020154492A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI845600B (zh) 2019-01-24 2024-06-21 美商普羅米修斯生物科學股份有限公司 Gpr35調節劑
EP3969621A4 (fr) 2019-05-14 2023-01-25 Prometheus Biosciences, Inc. Méthodes, systèmes et dispositifs de sélection de patient tl1a
AR123034A1 (es) * 2020-07-23 2022-10-26 Prometheus Biosciences Inc Agentes terapéuticos dirigidos a gpr35
JP2025513455A (ja) 2022-04-22 2025-04-24 バーテックス ファーマシューティカルズ インコーポレイテッド 疼痛の治療のためのヘテロアリール化合物
GB202303387D0 (en) * 2023-03-08 2023-04-19 Thirtyfivebio Ltd Compounds

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005119252A2 (fr) * 2004-05-26 2005-12-15 Arena Pharmaceuticals, Inc. Gpr35 et modulateur de gpr35 utilises pour traiter des troubles metaboliques
GB1421970A (en) * 1973-06-12 1976-01-21 May & Baker Ltd 8-azapurin-6-one derivatives
GB1338235A (en) * 1970-12-15 1973-11-21 May & Baker Ltd Azapurinones
US4052390A (en) * 1973-06-12 1977-10-04 May & Baker Limited Azapurinones
GB1561345A (en) 1976-10-22 1980-02-20 May & Baker Ltd 8 - azapuring - 6 - ones
US4923874A (en) 1988-07-21 1990-05-08 G. D. Searle & Co. Use of 8-azapurin-6-one derivatives for control of hypertension
US5474796A (en) 1991-09-04 1995-12-12 Protogene Laboratories, Inc. Method and apparatus for conducting an array of chemical reactions on a support surface
FR2845993B1 (fr) * 2002-10-16 2005-02-11 Univ Pasteur Composes pharmaceutiques inhibiteurs specifiques de la pde5 du muscle lisse, compositions pharmaceutiques les contenant et utilisations therapeutiques
WO2005085867A2 (fr) * 2004-02-27 2005-09-15 Pfizer Japan, Inc. Recepteur gpr35
US20070287630A1 (en) 2006-06-12 2007-12-13 Driwater, Inc. Moisturizing agent with nutrients
AU2012262021B2 (en) 2011-06-01 2016-07-28 Janus Biotherapeutics, Inc. Novel immune system modulators
KR102160389B1 (ko) 2013-08-05 2020-09-28 트위스트 바이오사이언스 코포레이션 드 노보 합성된 유전자 라이브러리
US20150273088A1 (en) * 2014-03-28 2015-10-01 Washington University Zaprinast analogues as glutaminase inhibitors and methods to predict response thereto
CA3168304A1 (fr) 2014-06-29 2016-01-07 Profile Products L.L.C. Substrat de culture a base de fibres d'ecorce et de bois
US10626180B2 (en) 2017-04-20 2020-04-21 Cedars-Sinai Medical Center Methods of treating and predicting non-response to anti-TNF treatment in subjects with inflammatory bowel disease
WO2019210203A1 (fr) 2018-04-27 2019-10-31 Cedars-Sinai Medical Center Compositions et procédés de ciblage de gpr35 pour le traitement d'une affection abdominale inflammatoire
TWI845600B (zh) 2019-01-24 2024-06-21 美商普羅米修斯生物科學股份有限公司 Gpr35調節劑
CA3128942A1 (fr) 2019-02-08 2020-08-13 Cedars-Sinai Medical Center Procedes, systemes et kits pour traiter une maladie inflammatoire ciblant skap2
JP2022519819A (ja) 2019-02-08 2022-03-25 シーダーズ―シナイ メディカル センター Il18r1を標的とする炎症性疾患を処置するための方法、システム、およびキット
EP3969621A4 (fr) 2019-05-14 2023-01-25 Prometheus Biosciences, Inc. Méthodes, systèmes et dispositifs de sélection de patient tl1a
CA3162905A1 (fr) 2019-11-27 2021-06-03 Cedars-Sinai Medical Center Prediction de manifestations extra-intestinales de maladies intestinales inflammatoires
AR123034A1 (es) 2020-07-23 2022-10-26 Prometheus Biosciences Inc Agentes terapéuticos dirigidos a gpr35
IL302791A (en) 2020-11-13 2023-07-01 Prometheus Biosciences Inc Methods, systems, and kits for treatment of inflammatory diseases targeting tl1a
EP4263585A4 (fr) 2020-12-21 2024-11-27 Cedars-Sinai Medical Center Compositions thérapeutiques de tl1a et méthodes de traitement les utilisant

Also Published As

Publication number Publication date
EP3914256B1 (fr) 2024-05-29
US20200239476A1 (en) 2020-07-30
US11773101B2 (en) 2023-10-03
MX2021008941A (es) 2021-10-13
IL285074A (en) 2021-09-30
CN113631168A (zh) 2021-11-09
EP3914256A1 (fr) 2021-12-01
US20210380590A1 (en) 2021-12-09
US11053251B2 (en) 2021-07-06
TW202043234A (zh) 2020-12-01
TWI845600B (zh) 2024-06-21
BR112021014566A2 (pt) 2022-01-04
IL285074B1 (en) 2024-08-01
AU2020210930A1 (en) 2021-09-09
CA3127786A1 (fr) 2020-07-30
WO2020154492A1 (fr) 2020-07-30
JP7588077B2 (ja) 2024-11-21
CN113631168B (zh) 2024-11-19
EP3914256A4 (fr) 2022-09-28
JP2022518523A (ja) 2022-03-15
KR102863894B1 (ko) 2025-09-23
AU2020210930B2 (en) 2025-08-14
IL285074B2 (en) 2024-12-01
KR20210119485A (ko) 2021-10-05

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