MA55082A - Compositions, procédés, et kits pour l'administration de polyribonucléotides - Google Patents
Compositions, procédés, et kits pour l'administration de polyribonucléotidesInfo
- Publication number
- MA55082A MA55082A MA055082A MA55082A MA55082A MA 55082 A MA55082 A MA 55082A MA 055082 A MA055082 A MA 055082A MA 55082 A MA55082 A MA 55082A MA 55082 A MA55082 A MA 55082A
- Authority
- MA
- Morocco
- Prior art keywords
- polyribonucleotides
- kits
- administration
- compositions
- methods
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962812763P | 2019-03-01 | 2019-03-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA55082A true MA55082A (fr) | 2022-01-05 |
Family
ID=70005812
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA055082A MA55082A (fr) | 2019-03-01 | 2020-03-01 | Compositions, procédés, et kits pour l'administration de polyribonucléotides |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20220088049A1 (fr) |
| EP (1) | EP3930683A1 (fr) |
| JP (2) | JP7526195B2 (fr) |
| KR (1) | KR20210134716A (fr) |
| CN (1) | CN113543770A (fr) |
| AU (1) | AU2020231349B2 (fr) |
| CA (1) | CA3128615A1 (fr) |
| IL (1) | IL285923A (fr) |
| MA (1) | MA55082A (fr) |
| WO (1) | WO2020180751A1 (fr) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MA51155A (fr) | 2017-12-15 | 2020-10-21 | Flagship Pioneering Innovations Vi Llc | Compositions comprenant des polyribonucléotides circulaires et leurs utilisations |
| EP3946466A2 (fr) | 2019-03-25 | 2022-02-09 | Flagship Pioneering Innovations VI, LLC | Compositions comprenant des polyribonucléotides circulaires modifiés et utilisations associées |
| EP4153152A1 (fr) * | 2020-05-20 | 2023-03-29 | Flagship Pioneering Innovations VI, LLC | Compositions et procédés de production d'anticorps polyclonaux humains |
| EP4464783A3 (fr) | 2021-09-17 | 2025-01-22 | Flagship Pioneering Innovations VI, LLC | Compositions et procédés de production de polyribonucléotides circulaires |
| WO2023096990A1 (fr) | 2021-11-24 | 2023-06-01 | Flagship Pioneering Innovation Vi, Llc | Compositions immunogènes de coronavirus et leurs utilisations |
| KR20240125931A (ko) | 2021-11-24 | 2024-08-20 | 플래그쉽 파이어니어링 이노베이션스 브이아이, 엘엘씨 | 수두-대상포진 바이러스 면역원 조성물 및 이의 용도 |
| US20250032604A1 (en) | 2021-11-24 | 2025-01-30 | Flagship Pioneering Innovations Vi, Llc | Immunogenic compositions and their uses |
| WO2023115013A1 (fr) | 2021-12-17 | 2023-06-22 | Flagship Pioneering Innovations Vi, Llc | Procédés d'enrichissement en arn circulaire dans des conditions de dénaturation |
| MX2024007870A (es) | 2021-12-23 | 2024-08-15 | Flagship Pioneering Innovations Vi Llc | Polirribonucleotidos circulares que codifican polipeptidos antifusogenicos. |
| AU2024212425A1 (en) | 2023-01-27 | 2025-08-07 | Sail Biomedicines, Inc. | A modified lipid composition and uses thereof |
| WO2024192422A1 (fr) | 2023-03-15 | 2024-09-19 | Flagship Pioneering Innovations Vi, Llc | Compositions immunogènes et leurs utilisations |
| JP2026509462A (ja) | 2023-03-15 | 2026-03-19 | フラッグシップ パイオニアリング イノベーションズ シックス,エルエルシー | ポリリボヌクレオチドを含む組成物及びその使用 |
| WO2025006684A1 (fr) | 2023-06-28 | 2025-01-02 | Flagship Pioneering Innovations Vi, Llc | Polyribonucléotides circulaires codant pour des polypeptides antifusogènes |
| WO2025240369A2 (fr) * | 2024-05-13 | 2025-11-20 | Helix Nanotechnologies Inc | Procédés de distribution de polyribonucléotides nus |
Family Cites Families (56)
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|---|---|---|---|---|
| US4069819A (en) | 1973-04-13 | 1978-01-24 | Societa Farmaceutici S.P.A. | Inhalation device |
| IT1016489B (it) | 1974-03-18 | 1977-05-30 | Isf Spa | Inalatore |
| US4283393A (en) * | 1979-03-13 | 1981-08-11 | Merck & Co., Inc. | Topical application of interferon inducers |
| US5266684A (en) | 1988-05-02 | 1993-11-30 | The Reagents Of The University Of California | Peptide mixtures |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| IT1228459B (it) | 1989-02-23 | 1991-06-19 | Phidea S R L | Inalatore con svuotamento regolare e completo della capsula. |
| JPH06500014A (ja) | 1990-07-25 | 1994-01-06 | シンジーン,インコーポレイテッド | 多数の核酸相補体を生成させる環状伸長法 |
| US5426180A (en) | 1991-03-27 | 1995-06-20 | Research Corporation Technologies, Inc. | Methods of making single-stranded circular oligonucleotides |
| JPH0558866A (ja) * | 1991-08-28 | 1993-03-09 | Lion Corp | 口腔用組成物 |
| ATE148889T1 (de) | 1991-09-18 | 1997-02-15 | Affymax Tech Nv | Verfahren zur synthese der verschiedenen sammlungen von oligomeren |
| US5639603A (en) | 1991-09-18 | 1997-06-17 | Affymax Technologies N.V. | Synthesizing and screening molecular diversity |
| JPH07502898A (ja) | 1992-01-13 | 1995-03-30 | デューク・ユニバーシティー | 酵素rna分子 |
| US5541061A (en) | 1992-04-29 | 1996-07-30 | Affymax Technologies N.V. | Methods for screening factorial chemical libraries |
| US5288514A (en) | 1992-09-14 | 1994-02-22 | The Regents Of The University Of California | Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support |
| US5721099A (en) | 1992-10-01 | 1998-02-24 | Trustees Of Columbia University In The City Of New York | Complex combinatorial chemical libraries encoded with tags |
| US5565324A (en) | 1992-10-01 | 1996-10-15 | The Trustees Of Columbia University In The City Of New York | Complex combinatorial chemical libraries encoded with tags |
| US5773244A (en) | 1993-05-19 | 1998-06-30 | Regents Of The University Of California | Methods of making circular RNA |
| US5440016A (en) | 1993-06-18 | 1995-08-08 | Torrey Pines Institute For Molecular Studies | Peptides of the formula (KFmoc) ZZZ and their uses |
| US5593853A (en) | 1994-02-09 | 1997-01-14 | Martek Corporation | Generation and screening of synthetic drug libraries |
| US5688997A (en) | 1994-05-06 | 1997-11-18 | Pharmacopeia, Inc. | Process for preparing intermediates for a combinatorial dihydrobenzopyran library |
| US5540934A (en) * | 1994-06-22 | 1996-07-30 | Touitou; Elka | Compositions for applying active substances to or through the skin |
| US5525735A (en) | 1994-06-22 | 1996-06-11 | Affymax Technologies Nv | Methods for synthesizing diverse collections of pyrrolidine compounds |
| US5549974A (en) | 1994-06-23 | 1996-08-27 | Affymax Technologies Nv | Methods for the solid phase synthesis of thiazolidinones, metathiazanones, and derivatives thereof |
| US5463564A (en) | 1994-09-16 | 1995-10-31 | 3-Dimensional Pharmaceuticals, Inc. | System and method of automatically generating chemical compounds with desired properties |
| US5688696A (en) | 1994-12-12 | 1997-11-18 | Selectide Corporation | Combinatorial libraries having a predetermined frequency of each species of test compound |
| ES2174075T3 (es) | 1995-06-21 | 2002-11-01 | Martek Biosciences Corp | Librerias combinatorias de compuestos bioquimicos marcados y metodos para producir las mismas. |
| US5766903A (en) | 1995-08-23 | 1998-06-16 | University Technology Corporation | Circular RNA and uses thereof |
| US5731423A (en) | 1996-03-21 | 1998-03-24 | Transcell Technologies, Inc. | Process for preparing sulfoxides |
| US6797276B1 (en) * | 1996-11-14 | 2004-09-28 | The United States Of America As Represented By The Secretary Of The Army | Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response |
| US6210931B1 (en) | 1998-11-30 | 2001-04-03 | The United States Of America As Represented By The Secretary Of Agriculture | Ribozyme-mediated synthesis of circular RNA |
| US8245708B2 (en) | 2002-05-07 | 2012-08-21 | The Research Foundation Of State University Of New York | Methods, devices and formulations for targeted endobronchial therapy |
| KR101033097B1 (ko) | 2002-05-07 | 2011-05-06 | 더 리서치 파운데이션 오브 스테이트 유니버시티 오브 뉴욕 | 표적 기관지내 요법을 위한 방법, 장치 및 제제 |
| DE102004025881A1 (de) * | 2004-05-19 | 2006-01-05 | Beiersdorf Ag | Oligoribonukleotide zur Beeinflussung des Haarwachstums |
| CN101060864A (zh) * | 2004-09-21 | 2007-10-24 | 阿尼西瓦股份有限公司 | 多核苷酸的递送 |
| EP1799271A4 (fr) * | 2004-09-21 | 2010-05-05 | Anesiva Inc | Administration de polynucléotides |
| DE102005046490A1 (de) | 2005-09-28 | 2007-03-29 | Johannes-Gutenberg-Universität Mainz | Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen |
| JP2009519033A (ja) | 2005-12-16 | 2009-05-14 | ディアト | 核酸を細胞に送達するための細胞貫通ペプチド結合体 |
| JP5295785B2 (ja) | 2006-02-20 | 2013-09-18 | エファ・ユニバーシティ・インダストリー・コラボレイション・ファウンデイション | 細胞膜透過性ペプチド |
| JP5296328B2 (ja) | 2007-05-09 | 2013-09-25 | 独立行政法人理化学研究所 | 1本鎖環状rnaおよびその製造方法 |
| JP5524189B2 (ja) | 2008-06-06 | 2014-06-18 | クォーク ファーマシューティカルズ インコーポレーティッド | 耳障害治療のための組成物および方法 |
| WO2010084371A1 (fr) | 2009-01-26 | 2010-07-29 | Mitoprod | Nouvelles molécules d'arn interférent circulaire |
| WO2011127255A1 (fr) * | 2010-04-08 | 2011-10-13 | Merck Sharp & Dohme Corp. | Préparation de nanoparticules de lipide |
| AU2011267078B2 (en) | 2010-06-14 | 2014-09-25 | F. Hoffmann-La Roche Ag | Cell-penetrating peptides and uses therof |
| RS63367B1 (sr) | 2010-08-31 | 2022-07-29 | Glaxosmithkline Biologicals Sa | Pegilovani lipozomi za isporuku rnk koja kodira imunogen |
| KR101938548B1 (ko) | 2011-06-23 | 2019-01-15 | (주)아모레퍼시픽 | 마이크로 rna를 포함하는 색소형성유전자 발현조절용 조성물 |
| ES2861428T3 (es) | 2011-07-06 | 2021-10-06 | Glaxosmithkline Biologicals Sa | Liposomas que presentan una relación N:P útil para suministro de moléculas de ARN |
| EP2765982A1 (fr) * | 2011-10-11 | 2014-08-20 | Hans Kosak | Diméthylsulfoxyde utilisé comme solvant pour des acides nucléiques |
| RU2649364C2 (ru) * | 2011-12-16 | 2018-04-02 | Модерна Терапьютикс, Инк. | Составы на основе модифицированного нуклеозида, нуклеотида и нуклеиновой кислоты |
| US10501512B2 (en) * | 2012-04-02 | 2019-12-10 | Modernatx, Inc. | Modified polynucleotides |
| WO2016036735A1 (fr) | 2014-09-05 | 2016-03-10 | The Johns Hopkins University | Particules pénétrant à travers le mucus, à base de liposomes, pour une administration par voie muqueuse |
| EP3256585A4 (fr) | 2015-02-13 | 2018-08-15 | Factor Bioscience Inc. | Produits d'acides nucléiques et leurs procédés d'administration |
| ES2910425T3 (es) * | 2015-09-17 | 2022-05-12 | Modernatx Inc | Compuestos y composiciones para la administración intracelular de agentes terapéuticos |
| CN105664239B (zh) * | 2016-03-23 | 2018-08-07 | 成都交大麦迪克科技有限公司 | 一种自粘附皮肤修复水凝胶的制备方法 |
| CA3028682A1 (fr) * | 2016-06-20 | 2017-12-28 | Howard Y. Chang | Arn circulaires et leur utilisation dans l'immunomodulation |
| RU2019121992A (ru) | 2016-12-14 | 2021-01-15 | Лигандал, Инк. | Способы и композиции для доставки полезной нагрузки в виде нуклеиновых кислот и белков |
| JP7209951B2 (ja) | 2017-10-30 | 2023-01-23 | 日本メナード化粧品株式会社 | 白髪予防及び改善剤 |
-
2020
- 2020-03-01 CA CA3128615A patent/CA3128615A1/fr active Pending
- 2020-03-01 WO PCT/US2020/020560 patent/WO2020180751A1/fr not_active Ceased
- 2020-03-01 JP JP2021551747A patent/JP7526195B2/ja active Active
- 2020-03-01 CN CN202080017993.7A patent/CN113543770A/zh active Pending
- 2020-03-01 US US17/433,658 patent/US20220088049A1/en active Pending
- 2020-03-01 AU AU2020231349A patent/AU2020231349B2/en active Active
- 2020-03-01 KR KR1020217031380A patent/KR20210134716A/ko active Pending
- 2020-03-01 MA MA055082A patent/MA55082A/fr unknown
- 2020-03-01 EP EP20714431.2A patent/EP3930683A1/fr active Pending
-
2021
- 2021-08-29 IL IL285923A patent/IL285923A/en unknown
-
2024
- 2024-07-19 JP JP2024115650A patent/JP2024147750A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN113543770A (zh) | 2021-10-22 |
| EP3930683A1 (fr) | 2022-01-05 |
| KR20210134716A (ko) | 2021-11-10 |
| JP2024147750A (ja) | 2024-10-16 |
| IL285923A (en) | 2021-10-31 |
| JP2022523222A (ja) | 2022-04-21 |
| AU2020231349A1 (en) | 2021-09-23 |
| US20220088049A1 (en) | 2022-03-24 |
| WO2020180751A1 (fr) | 2020-09-10 |
| AU2020231349B2 (en) | 2025-10-23 |
| CA3128615A1 (fr) | 2020-09-10 |
| JP7526195B2 (ja) | 2024-07-31 |
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