MA55517A - Composés macrocycliques utilisés en tant qu'agonistes sting - Google Patents
Composés macrocycliques utilisés en tant qu'agonistes stingInfo
- Publication number
- MA55517A MA55517A MA055517A MA55517A MA55517A MA 55517 A MA55517 A MA 55517A MA 055517 A MA055517 A MA 055517A MA 55517 A MA55517 A MA 55517A MA 55517 A MA55517 A MA 55517A
- Authority
- MA
- Morocco
- Prior art keywords
- compounds used
- macrocyclic compounds
- sting agonists
- sting
- agonists
- Prior art date
Links
- 229940044665 STING agonist Drugs 0.000 title 1
- 150000002678 macrocyclic compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/16—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/537—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines spiro-condensed or forming part of bridged ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN201921012258 | 2019-03-28 | ||
| IN201921046194 | 2019-11-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA55517A true MA55517A (fr) | 2022-02-09 |
Family
ID=70293003
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA055517A MA55517A (fr) | 2019-03-28 | 2020-03-21 | Composés macrocycliques utilisés en tant qu'agonistes sting |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US20220144852A1 (fr) |
| EP (1) | EP3946610A1 (fr) |
| JP (1) | JP7530380B2 (fr) |
| KR (1) | KR20210146370A (fr) |
| CN (1) | CN113631228B (fr) |
| AU (1) | AU2020245263B2 (fr) |
| BR (1) | BR112021018947A2 (fr) |
| CA (1) | CA3132508A1 (fr) |
| CL (1) | CL2021002480A1 (fr) |
| CO (1) | CO2021012559A2 (fr) |
| CR (1) | CR20210495A (fr) |
| EC (1) | ECSP21071644A (fr) |
| IL (1) | IL286526A (fr) |
| MA (1) | MA55517A (fr) |
| MX (1) | MX2021011686A (fr) |
| PE (1) | PE20220169A1 (fr) |
| PH (1) | PH12021552263A1 (fr) |
| SG (1) | SG11202109191SA (fr) |
| WO (1) | WO2020194160A1 (fr) |
| ZA (1) | ZA202106629B (fr) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20220937A1 (es) | 2019-07-22 | 2022-05-31 | Lupin Ltd | Compuestos macrociclicos como agonistas de sting y metodos y usos de los mismos |
| CA3149482A1 (fr) | 2019-08-02 | 2021-02-11 | Mersana Therapeutics, Inc. | Derives de bis-[n-((5-carbamoyl)-1h-benzo[d]imidazol-2-yl)-pyrazol-5-carboxamide] et composes apparentes utilises en tant qu'agonistes de sting (stimulateur des genes de l'interferon) pour le traitement du cancer |
| BR112022019919A2 (pt) | 2020-04-02 | 2023-02-14 | Mersana Therapeutics Inc | Conjugado de anticorpo-fármaco compreendendo agonistas de sting |
| WO2021206158A1 (fr) | 2020-04-10 | 2021-10-14 | 小野薬品工業株式会社 | Méthode de cancérothérapie |
| WO2022155518A1 (fr) * | 2021-01-15 | 2022-07-21 | Seagen Inc. | Conjugués anticorps-médicament immunomodulateurs |
| AR133266A1 (es) * | 2023-07-19 | 2025-09-10 | Hoffmann La Roche | Macrociclos para el tratamiento de enfermedades autoinmunitarias |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104513253A (zh) * | 2013-10-01 | 2015-04-15 | 南京波尔泰药业科技有限公司 | 用于治疗增殖性疾病的大环化合物 |
| JP6835727B2 (ja) * | 2015-02-05 | 2021-02-24 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung | Irak1/4阻害剤としての大環状化合物及びその使用 |
| EP3325473A4 (fr) | 2015-07-22 | 2019-06-26 | The Royal Institution for the Advancement of Learning / McGill University | Composés et leurs utilisations dans le traitement de cancers et d'autres états médicaux |
| AR107032A1 (es) | 2015-12-09 | 2018-03-14 | Padlock Therapeutics Inc | Inhibidores bicíclicos de pad4 |
| KR20180132783A (ko) | 2016-04-07 | 2018-12-12 | 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 | 단백질 조절제로서 유용한 헤테로사이클릭 아미드 |
| CN113549110B (zh) * | 2016-04-07 | 2024-08-16 | 葛兰素史密斯克莱知识产权发展有限公司 | 用作蛋白质调节剂的杂环酰胺 |
| CA3067257A1 (fr) | 2017-06-22 | 2018-12-27 | Curadev Pharma Limited | Modulateurs a petites molecules de sting humain |
| JP2020524718A (ja) | 2017-06-22 | 2020-08-20 | キュラデブ・ファーマ・リミテッドCuradev Pharma Limited | ヒトstingの複素環式小分子調節因子 |
| JP2020524717A (ja) * | 2017-06-22 | 2020-08-20 | キュラデブ・ファーマ・リミテッドCuradev Pharma Limited | ヒトstingの小分子調節因子 |
| WO2019023635A1 (fr) | 2017-07-27 | 2019-01-31 | Stingray Therapeutics, Inc. | Série de 3 h-imidazo(4,5-c)pyridine substituée et de 1h-pyrrolo(2,3-c)pyridine d'une nouvelle ectonucléotide pyrophosphatase/phosphodiestérase-1 (enpp1) et stimulateur pour un modulateur de gènes d'interféron (sting) en tant qu'agents immunothérapeutiques contre le cancer |
| AU2018311965A1 (en) | 2017-08-04 | 2020-02-13 | Merck Sharp & Dohme Llc | Combinations of PD-1 antagonists and benzo[b]thiophene sting antagonists for cancer treatment |
| JP2020530838A (ja) | 2017-08-04 | 2020-10-29 | メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. | がん治療のためのベンゾ[b]チオフェンSTINGアゴニスト |
-
2020
- 2020-03-21 MA MA055517A patent/MA55517A/fr unknown
- 2020-03-21 BR BR112021018947A patent/BR112021018947A2/pt unknown
- 2020-03-21 SG SG11202109191SA patent/SG11202109191SA/en unknown
- 2020-03-21 WO PCT/IB2020/052654 patent/WO2020194160A1/fr not_active Ceased
- 2020-03-21 EP EP20719719.5A patent/EP3946610A1/fr active Pending
- 2020-03-21 CN CN202080025785.1A patent/CN113631228B/zh active Active
- 2020-03-21 KR KR1020217035108A patent/KR20210146370A/ko not_active Ceased
- 2020-03-21 MX MX2021011686A patent/MX2021011686A/es unknown
- 2020-03-21 PE PE2021001577A patent/PE20220169A1/es unknown
- 2020-03-21 AU AU2020245263A patent/AU2020245263B2/en active Active
- 2020-03-21 CR CR20210495A patent/CR20210495A/es unknown
- 2020-03-21 CA CA3132508A patent/CA3132508A1/fr active Pending
- 2020-03-21 PH PH1/2021/552263A patent/PH12021552263A1/en unknown
- 2020-03-21 US US17/598,524 patent/US20220144852A1/en active Pending
- 2020-03-21 JP JP2021557830A patent/JP7530380B2/ja active Active
-
2021
- 2021-09-08 ZA ZA2021/06629A patent/ZA202106629B/en unknown
- 2021-09-19 IL IL286526A patent/IL286526A/en unknown
- 2021-09-24 CL CL2021002480A patent/CL2021002480A1/es unknown
- 2021-09-24 EC ECSENADI202171644A patent/ECSP21071644A/es unknown
- 2021-09-24 CO CONC2021/0012559A patent/CO2021012559A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN113631228A (zh) | 2021-11-09 |
| SG11202109191SA (en) | 2021-09-29 |
| JP7530380B2 (ja) | 2024-08-07 |
| ECSP21071644A (es) | 2021-12-30 |
| CO2021012559A2 (es) | 2021-09-30 |
| CA3132508A1 (fr) | 2020-10-01 |
| AU2020245263B2 (en) | 2025-07-03 |
| PH12021552263A1 (en) | 2022-07-11 |
| AU2020245263A1 (en) | 2021-10-07 |
| JP2022527306A (ja) | 2022-06-01 |
| EP3946610A1 (fr) | 2022-02-09 |
| CR20210495A (es) | 2021-10-18 |
| MX2021011686A (es) | 2021-10-22 |
| US20220144852A1 (en) | 2022-05-12 |
| IL286526A (en) | 2021-10-31 |
| BR112021018947A2 (pt) | 2022-02-08 |
| CL2021002480A1 (es) | 2022-04-29 |
| KR20210146370A (ko) | 2021-12-03 |
| CN113631228B (zh) | 2023-10-13 |
| ZA202106629B (en) | 2022-07-27 |
| WO2020194160A1 (fr) | 2020-10-01 |
| PE20220169A1 (es) | 2022-01-28 |
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