MA55564A - Composés de pyrrole - Google Patents

Composés de pyrrole

Info

Publication number
MA55564A
MA55564A MA055564A MA55564A MA55564A MA 55564 A MA55564 A MA 55564A MA 055564 A MA055564 A MA 055564A MA 55564 A MA55564 A MA 55564A MA 55564 A MA55564 A MA 55564A
Authority
MA
Morocco
Prior art keywords
pyrrole compounds
pyrrole
compounds
Prior art date
Application number
MA055564A
Other languages
English (en)
Inventor
Franck Amblard
Leda Bassit
Leonid Beigelman
Raymond F Schinazi
Vladimir Serebryany
David Bernard Smith
Sandrine Vendeville
Original Assignee
Aligos Therapeutics Inc
Univ Emory
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aligos Therapeutics Inc, Univ Emory filed Critical Aligos Therapeutics Inc
Publication of MA55564A publication Critical patent/MA55564A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4192—1,2,3-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/094—Esters of phosphoric acids with arylalkanols

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
MA055564A 2019-04-03 2020-04-01 Composés de pyrrole MA55564A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962828919P 2019-04-03 2019-04-03
US201962932686P 2019-11-08 2019-11-08

Publications (1)

Publication Number Publication Date
MA55564A true MA55564A (fr) 2022-02-09

Family

ID=72667046

Family Applications (1)

Application Number Title Priority Date Filing Date
MA055564A MA55564A (fr) 2019-04-03 2020-04-01 Composés de pyrrole

Country Status (23)

Country Link
US (3) US11191747B2 (fr)
EP (2) EP4733305A2 (fr)
JP (3) JP7627008B2 (fr)
KR (2) KR102933784B1 (fr)
CN (4) CN121108034A (fr)
AU (2) AU2020253444C1 (fr)
BR (1) BR112021019817A2 (fr)
CA (1) CA3134635A1 (fr)
CL (1) CL2021002575A1 (fr)
CO (1) CO2021014210A2 (fr)
DK (1) DK3947349T3 (fr)
FI (1) FI3947349T3 (fr)
GE (2) GEAP202515762A (fr)
IL (1) IL286902B2 (fr)
MA (1) MA55564A (fr)
MX (1) MX2021012105A (fr)
PE (1) PE20220252A1 (fr)
PH (1) PH12021552513A1 (fr)
PT (1) PT3947349T (fr)
SG (1) SG11202110718PA (fr)
TW (1) TWI846853B (fr)
UA (1) UA129029C2 (fr)
WO (1) WO2020205934A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102933784B1 (ko) 2019-04-03 2026-03-06 알리고스 테라퓨틱스 인코포레이티드 피롤 화합물
WO2022143610A1 (fr) * 2020-12-29 2022-07-07 广东东阳光药业有限公司 Nouveaux composés d'amide pyrrole et leur utilisation dans des médicaments
WO2022156758A1 (fr) * 2021-01-22 2022-07-28 广东东阳光药业有限公司 Nouveau composé amide pyrrole et son utilisation dans des médicaments
CN118201942A (zh) 2021-09-08 2024-06-14 阿利戈斯治疗公司 经修饰的短干扰核酸(siNA)分子和其用途
CN116768776B (zh) * 2022-03-17 2024-07-02 成都微芯药业有限公司 吡咯酰胺类化合物及其制备方法和用途
CN116120219A (zh) * 2022-12-27 2023-05-16 吉斯凯(苏州)制药有限公司 一种多取代吡咯类化合物及其制备方法和在制备hbv衣壳蛋白抑制剂中的应用
AU2024212652A1 (en) * 2023-01-26 2025-07-10 Aligos Therapeutics, Inc. Hepatitis b combination therapies

Family Cites Families (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4784782A (en) 1986-03-27 1988-11-15 The Lubrizol Corporation Heterocyclic compounds useful as additives for lubricant and fuel compositions
WO2002006278A1 (fr) 2000-07-17 2002-01-24 Ranbaxy Laboratories Limited Derives d'oxazolidinone utilises en tant qu'antimicrobiens
WO2002085908A1 (fr) 2001-04-24 2002-10-31 Purdue Research Foundation Mimetiques de folate et ses conjugues de liaison aux recepteurs de folate
US6956040B2 (en) 2001-07-16 2005-10-18 Ranbaxy Laboratories Limited Oxazolidinone piperazinyl derivatives as potential antimicrobials
GB0119172D0 (en) 2001-08-06 2001-09-26 Melacure Therapeutics Ab Phenyl pyrrole derivatives
NZ541234A (en) 2002-12-20 2008-06-30 Amgen Inc Asthma and allergic inflammation modulators
US7202257B2 (en) 2003-12-24 2007-04-10 Deciphera Pharmaceuticals, Llc Anti-inflammatory medicaments
GB2398299A (en) 2003-02-13 2004-08-18 Melacure Therapeutics Ab Pharmaceutically active phenyl-pyrrole derivatives
US20070191336A1 (en) 2003-12-24 2007-08-16 Flynn Daniel L Anti-inflammatory medicaments
US7732446B1 (en) 2004-03-11 2010-06-08 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
AU2005221959C1 (en) 2004-03-13 2010-06-17 Kyoto University Novel indole derivative for alkylating specific base sequence of DNA and alkylating agent and drug each comprising the same
US20060105355A1 (en) 2004-11-18 2006-05-18 Karl Maurer Electrode array device having an adsorbed porous reaction layer having a linker moiety
US20060102471A1 (en) 2004-11-18 2006-05-18 Karl Maurer Electrode array device having an adsorbed porous reaction layer
WO2006092059A1 (fr) 2005-03-04 2006-09-08 Fan Wu Conception et synthese de nouvelles substances antimicrobiennes
US20100234379A1 (en) 2005-07-28 2010-09-16 Bahr Ben A Dual modulation of endocannabinoid transport and fatty-acid amide hydrolase for treatment of excitotoxicity
US20070065877A1 (en) 2005-09-19 2007-03-22 Combimatrix Corporation Microarray having a base cleavable succinate linker
WO2008033562A2 (fr) 2006-09-15 2008-03-20 Xcovery, Inc. Composés inhibiteurs de kinases
CA2688136A1 (fr) 2007-06-08 2008-12-11 Advinus Therapeutics Private Limited Nouveaux derives de pyrrole-2-carboxamide en tant qu'activateurs de la glucokinase, leur procede d'obtention et leur application pharmaceutique
CA2690243A1 (fr) 2007-06-18 2008-12-24 Sanofi-Aventis Derives du pyrrole en tant qu'antagonistes de p2y12
CA2754492A1 (fr) 2009-03-05 2010-09-10 Purdue Research Foundation Methode d'imagerie precoce de l'atherosclerose
EP2408770B1 (fr) 2009-03-20 2014-11-05 University Of Virginia Patent Foundation Benzothiophène-nitrothiazolide à spectre large et autres antimicrobiens
JP2013508413A (ja) 2009-10-22 2013-03-07 ヴァンダービルト ユニバーシティー ｍＧｌｕＲ４アロステリック増強剤、組成物、および神経機能不全を治療する方法
RU2012154447A (ru) 2010-05-12 2014-06-20 Вандербилт Юниверсити Гетероциклические сульфоновые аллостерические потенциаторы mglur4, композиции и способы лечения неврологических дисфункций
BR112012032247A2 (pt) 2010-06-15 2015-09-15 Bayer Ip Gmbh derivados de ácido antranílico
SI2616444T1 (sl) 2010-09-14 2016-03-31 Instytut Biochemii I Biofizyki Pan Spojine kot modulatorji mutantnega cftr proteina in njihova uporaba za zdravljenje bolezni, povezanih s cftr proteinsko okvaro
WO2012047525A2 (fr) 2010-09-27 2012-04-12 Endocyte, Inc. Conjugués de l'acide folique destinés à traiter une inflammation de l'œil
WO2012078902A2 (fr) 2010-12-08 2012-06-14 Proteostasis Therapeutics, Inc. Régulateurs de la protéostasie
WO2012087976A2 (fr) 2010-12-21 2012-06-28 Intermune, Inc. Nouveaux inhibiteurs de la réplication du virus de l'hépatite c
WO2012154880A1 (fr) 2011-05-09 2012-11-15 Proteostasis Therapeutics, Inc. Régulateurs de protéostasie pour le traitement de la mucoviscidose et autres maladies de mauvais repliement des protéines
US20130072473A1 (en) 2011-05-09 2013-03-21 Proteostasis Therapeutics, Inc. Compounds for treating protein folding disorders
RS58718B1 (sr) 2011-05-12 2019-06-28 Proteostasis Therapeutics Inc Regulatori proteostaze
JP5977347B2 (ja) 2011-07-01 2016-08-24 バルーク エス．ブルームバーグ インスティテュート Ｈｂｖ感染に対する抗ウイルス剤としてのスルファモイルベンズアミド誘導体
US8835640B1 (en) 2011-11-16 2014-09-16 Paresh T. Gandhi Nicotine derivatives
HK1210969A1 (en) 2012-01-20 2016-05-13 奥克塞拉有限公司 Substituted heterocyclic compounds for disease treatment
EP3345597A3 (fr) 2012-09-19 2018-08-22 Faller & Williams Technology, LLC Inhibiteurs de pkc delta destinés à être utilisés comme substances thérapeutiques
JO3583B1 (ar) 2013-05-17 2020-07-05 Janssen Sciences Ireland Uc مشتقات سلفامويل بيرولاميد واستخدامها كادوية لمعالجة التهاب الكبد نوع بي
NO3024819T3 (fr) 2013-07-25 2018-07-21
MX368158B (es) 2013-10-23 2019-09-20 Janssen Sciences Ireland Uc Derivados de carboxamida y su uso como medicamentos para el tratamiento de la hepatitis b.
CN104672221B (zh) 2013-11-29 2018-01-23 中国科学院上海有机化学研究所 一种氟代苯并杂环‑杂芳环结构的合成方法
WO2015134539A1 (fr) 2014-03-03 2015-09-11 The Regents Of The University Of California Antagonistes de mcl-1
DE102014108210A1 (de) 2014-06-11 2015-12-17 Dietrich Gulba Rodentizid
US20160166679A1 (en) 2014-12-12 2016-06-16 Purdue Research Foundation Method of treatment using folate conjugates and tyrosine kinase inhibitors
KR101726060B1 (ko) 2015-07-28 2017-04-12 한양대학교 산학협력단 디피롤 유도체와 금속 염을 포함하는 염화수소 가스 검출용 조성물 및 이를 포함하는 염화수소 가스 검출용 색변환 센서
KR101726059B1 (ko) 2015-07-28 2017-04-12 한양대학교 산학협력단 디피롤 유도체와 암모늄 염을 포함하는 브롬화수소 가스 검출용 조성물 및 이를 포함하는 브롬화수소 가스 검출용 색변환 센서
WO2017081615A1 (fr) 2015-11-09 2017-05-18 Wockhardt Limited 7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1] octane contenant des composés et leur utilisation dans le traitement d'infections bactériennes
AU2017231817B2 (en) 2016-03-09 2021-02-25 Emory University Elimination of hepatitis B virus with antiviral agents
JOP20190024A1 (ar) 2016-08-26 2019-02-19 Gilead Sciences Inc مركبات بيروليزين بها استبدال واستخداماتها
CN108250121A (zh) 2016-12-28 2018-07-06 上海长森药业有限公司 磺酰胺-芳基酰胺类化合物及其治疗乙型肝炎的药物用途
CA3094022A1 (fr) 2018-03-30 2019-10-03 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Inhibiteur d'assemblage de proteines capsidiques contenant un cycle a cinq chainons n-heterocyclique, composition pharmaceutique et utilisation associees
CA3113109A1 (fr) 2018-10-05 2020-04-09 Emory University Agents anti-vhb monomeres et multimeres
US11096931B2 (en) 2019-02-22 2021-08-24 Janssen Sciences Ireland Unlimited Company Amide derivatives useful in the treatment of HBV infection or HBV-induced diseases
KR102933784B1 (ko) 2019-04-03 2026-03-06 알리고스 테라퓨틱스 인코포레이티드 피롤 화합물
US11903924B2 (en) 2019-11-13 2024-02-20 Xi'an Xintong Pharmaceutical Research Co., Ltd. HBV inhibitor and its use
WO2022143610A1 (fr) 2020-12-29 2022-07-07 广东东阳光药业有限公司 Nouveaux composés d'amide pyrrole et leur utilisation dans des médicaments

Also Published As

Publication number Publication date
IL286902A (en) 2021-10-31
FI3947349T3 (fi) 2026-04-23
TWI846853B (zh) 2024-07-01
TW202102474A (zh) 2021-01-16
JP7811768B2 (ja) 2026-02-06
US12599582B2 (en) 2026-04-14
CA3134635A1 (fr) 2020-10-08
DK3947349T3 (da) 2026-03-30
CN121108187A (zh) 2025-12-12
JP2024153620A (ja) 2024-10-29
KR102933784B1 (ko) 2026-03-06
EP4733305A2 (fr) 2026-04-29
US20230390242A1 (en) 2023-12-07
AU2020253444A1 (en) 2021-10-14
CL2021002575A1 (es) 2022-04-29
KR20220004996A (ko) 2022-01-12
AU2020253444B2 (en) 2025-05-29
CN114258391A (zh) 2022-03-29
PH12021552513A1 (en) 2022-10-03
AU2020253444C1 (en) 2025-12-11
JP2025146846A (ja) 2025-10-03
KR20260036605A (ko) 2026-03-17
SG11202110718PA (en) 2021-10-28
JP2022522312A (ja) 2022-04-15
EP3947349B1 (fr) 2026-03-11
CN121108034A (zh) 2025-12-12
EP3947349A4 (fr) 2022-11-23
JP7710215B2 (ja) 2025-07-18
US20200323821A1 (en) 2020-10-15
AU2025217289A1 (en) 2025-09-04
IL286902B2 (en) 2025-03-01
PE20220252A1 (es) 2022-02-16
CN121085825A (zh) 2025-12-09
JP7627008B2 (ja) 2025-02-05
GEAP202515762A (en) 2025-02-10
EP3947349A1 (fr) 2022-02-09
IL286902B1 (en) 2024-11-01
US11191747B2 (en) 2021-12-07
US11771680B2 (en) 2023-10-03
GEP20257772B (en) 2025-06-10
WO2020205934A1 (fr) 2020-10-08
MX2021012105A (es) 2021-11-03
US20220071957A1 (en) 2022-03-10
BR112021019817A2 (pt) 2021-12-07
CO2021014210A2 (es) 2022-01-17
UA129029C2 (uk) 2024-12-25
PT3947349T (pt) 2026-04-29

Similar Documents

Publication Publication Date Title
MA56115A (fr) Composés de pyrrolidine
IL292753A (en) Compounds
EP3956033A4 (fr) Composés bicycliques
DK4081521T3 (da) Substituerede tricykliske forbindelser
DK4065575T3 (da) Substituerede tricycliske forbindelser
EP3836923A4 (fr) Composés pyrrolo-dipyridine
MA52948A (fr) Composés
EP3941898C0 (fr) Composés fongicides
EP4054724A4 (fr) Composés bifonctionnels
EP3691623A4 (fr) Composés de benzosulfonyle
MA52560A (fr) Composés hétéroaryles tétracycliques
MA51669A (fr) Composés
EP3802467A4 (fr) Composés spirocycliques
EP4061364A4 (fr) Composés hétéroaryles
EP3781156A4 (fr) Composés spirocycliques
EP3720430A4 (fr) Composés benzocarbonyle
EP3947349A4 (fr) Composés de pyrrole
MA53003A (fr) Composés
EP3853210A4 (fr) Composés antibactériens
EP3924358A4 (fr) Composés macrocycliques
EP4077318A4 (fr) Composés
MA52946A (fr) Composés
EP3728289A4 (fr) Composés optimisés
EP3948222A4 (fr) Éditeur de compensation
EP3713941A4 (fr) Composés de pyrazolopyridinone