MA56115A - Composés de pyrrolidine - Google Patents

Composés de pyrrolidine

Info

Publication number
MA56115A
MA56115A MA056115A MA56115A MA56115A MA 56115 A MA56115 A MA 56115A MA 056115 A MA056115 A MA 056115A MA 56115 A MA56115 A MA 56115A MA 56115 A MA56115 A MA 56115A
Authority
MA
Morocco
Prior art keywords
pyrrolidine compounds
pyrrolidine
compounds
Prior art date
Application number
MA056115A
Other languages
English (en)
Inventor
Buezo Nuria Diaz
Blanco Celia Lafuente
Perez Jose Antonio Martinez
Soler Julian Priego
Gil Gema Consuelo Sanz
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of MA56115A publication Critical patent/MA56115A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/06Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epidemiology (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
MA056115A 2019-06-07 2020-06-03 Composés de pyrrolidine MA56115A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP19382477 2019-06-07

Publications (1)

Publication Number Publication Date
MA56115A true MA56115A (fr) 2022-04-13

Family

ID=66821161

Family Applications (1)

Application Number Title Priority Date Filing Date
MA056115A MA56115A (fr) 2019-06-07 2020-06-03 Composés de pyrrolidine

Country Status (25)

Country Link
US (3) US11286249B2 (fr)
EP (1) EP3980409A1 (fr)
JP (4) JP6940717B2 (fr)
KR (3) KR102720992B1 (fr)
CN (1) CN114008021B (fr)
AU (1) AU2020287599B2 (fr)
BR (1) BR112021023347A2 (fr)
CL (1) CL2021003202A1 (fr)
CO (1) CO2021016295A2 (fr)
CR (1) CR20210602A (fr)
DO (1) DOP2021000254A (fr)
EA (1) EA202193007A1 (fr)
EC (1) ECSP21088515A (fr)
IL (2) IL288174B2 (fr)
JO (1) JOP20210319B1 (fr)
MA (1) MA56115A (fr)
MX (2) MX2021014913A (fr)
MY (1) MY200810A (fr)
PE (1) PE20220134A1 (fr)
PH (1) PH12021553062A1 (fr)
SA (1) SA521431048B1 (fr)
SG (1) SG11202113244UA (fr)
UA (1) UA128540C2 (fr)
WO (1) WO2020247429A1 (fr)
ZA (1) ZA202109251B (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3235992A1 (fr) 2021-11-03 2023-05-11 Liang Tan Derive d'acide phenylpropionique substitue et son utilisation
MX2024009161A (es) 2022-01-26 2024-08-06 Lilly Co Eli Compuestos de pirrolidina.
WO2024199070A1 (fr) * 2023-03-24 2024-10-03 上海京新生物医药有限公司 Dérivé d'amine cyclique, composition et utilisation associées
WO2024217537A1 (fr) * 2023-04-21 2024-10-24 深圳信立泰药业股份有限公司 Composé amine tertiaire ainsi que son procédé de préparation et son utilisation médicale
TW202444710A (zh) 2023-05-11 2024-11-16 大陸商江蘇恆瑞醫藥股份有限公司 一種脂蛋白化合物晶型及其製備方法
EP4714939A1 (fr) * 2023-05-19 2026-03-25 Shenzhen Salubris Pharmaceuticals Co., Ltd. Composé sulfonamide, son procédé de préparation et son utilisation pharmaceutique
CN121443287A (zh) 2023-06-30 2026-01-30 伊莱利利公司 Lp(a)干扰剂化合物的治疗用途及剂量
WO2025024211A1 (fr) 2023-07-21 2025-01-30 Eli Lilly And Company Composés de pipéridine ayant une activité d'abaissement de lp(a)
AU2024298539A1 (en) 2023-07-21 2026-01-22 Eli Lilly And Company PYRROLIDINE COMPOUNDS WITH Lp(a) LOWERING ACTIVITY
WO2025024216A1 (fr) 2023-07-21 2025-01-30 Eli Lilly And Company Composés de pyrrolidine ayant une activité d'abaissement du taux de lp(a)
WO2025024210A1 (fr) 2023-07-21 2025-01-30 Eli Lilly And Company Composés pipéridines, morpholines et tétrahydropyridazines ayant une activité d'abaissement de la lp(a)
CN119490445A (zh) * 2023-08-15 2025-02-21 深圳信立泰药业股份有限公司 一种酰基类化合物及其制备方法和医药用途
WO2025103442A1 (fr) * 2023-11-17 2025-05-22 上海翊石医药科技有限公司 Dérivé d'acide 2-(pyrrolidin-3-yl)acétique substitué, son procédé de préparation et son utilisation
WO2025108255A1 (fr) * 2023-11-20 2025-05-30 上海齐鲁制药研究中心有限公司 Dérivé polycyclique, son procédé de préparation et son utilisation
WO2025237188A1 (fr) * 2024-05-14 2025-11-20 石家庄以岭药业股份有限公司 Composé inhibiteur de lp(a) et son utilisation

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2685325B1 (fr) * 1991-12-20 1994-02-04 Adir Cie Nouveaux derives de pyrrolidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US7371777B2 (en) * 2001-08-17 2008-05-13 Eisai Co., Ltd. Cyclic compound and PPAR agonist
AU2003300438A1 (en) 2003-12-24 2005-08-03 Esperion Therapeutics, Inc. Ether compounds and compositions for cholesterol management and related uses
JP2007525408A (ja) * 2003-12-24 2007-09-06 エスペリオン セラピューティクス,インコーポレイテッド コレステロール管理および関連使用のためのケトン化合物および組成物
WO2009016048A1 (fr) * 2007-07-27 2009-02-05 F. Hoffmann-La Roche Ag 2-azétidineméthaneamines et 2-pyrrolidineméthaneamines comme ligands de taar
JP2019505508A (ja) * 2016-02-03 2019-02-28 シャンハイ ハイヤン ファーマシューティカル テクノロジー カンパニー リミテッドShanghai Haiyan Pharmaceutical Technology Co., Ltd. 複素環置換n−スルホニルベンズアミド誘導体、その製造方法および医薬における使用
CN112321475B (zh) 2020-11-13 2022-06-10 四川大学 一种γ-氨基酸类似物及其合成方法

Also Published As

Publication number Publication date
CL2021003202A1 (es) 2022-09-09
AU2020287599B2 (en) 2023-10-19
JP6940717B2 (ja) 2021-09-29
JP2021524498A (ja) 2021-09-13
JOP20210319B1 (ar) 2024-12-22
MX2025001789A (es) 2025-03-07
US20220169636A1 (en) 2022-06-02
BR112021023347A2 (pt) 2022-04-12
NZ782992A (en) 2025-02-28
DOP2021000254A (es) 2022-01-16
IL288174A (en) 2022-01-01
SA521431048B1 (ar) 2024-04-28
KR102477481B1 (ko) 2022-12-15
MX2021014913A (es) 2022-01-18
SG11202113244UA (en) 2021-12-30
JP7508422B2 (ja) 2024-07-01
CN114008021B (zh) 2024-11-05
WO2020247429A1 (fr) 2020-12-10
US12441714B2 (en) 2025-10-14
MY200810A (en) 2024-01-16
CN114008021A (zh) 2022-02-01
KR102629923B1 (ko) 2024-01-30
CR20210602A (es) 2022-01-06
EA202193007A1 (ru) 2022-03-25
US11286249B2 (en) 2022-03-29
AU2020287599A1 (en) 2022-01-06
KR20240014618A (ko) 2024-02-01
PE20220134A1 (es) 2022-01-27
JP2021191784A (ja) 2021-12-16
KR102720992B1 (ko) 2024-10-24
JOP20210319A1 (ar) 2023-01-30
ZA202109251B (en) 2024-04-24
ECSP21088515A (es) 2022-01-31
CA3140869A1 (fr) 2020-12-10
JP2024123111A (ja) 2024-09-10
JP7658014B2 (ja) 2025-04-07
KR20220018494A (ko) 2022-02-15
IL288174B2 (en) 2025-12-01
PH12021553062A1 (en) 2022-08-15
EP3980409A1 (fr) 2022-04-13
JP2025098178A (ja) 2025-07-01
IL288174B1 (en) 2025-08-01
UA128540C2 (uk) 2024-08-07
IL321703A (en) 2025-08-01
KR20230004890A (ko) 2023-01-06
US20260055086A1 (en) 2026-02-26
CO2021016295A2 (es) 2021-12-10
US20210253559A1 (en) 2021-08-19

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