MA56187A - Traitements de l'angio-oedème héréditaire - Google Patents

Traitements de l'angio-oedème héréditaire

Info

Publication number
MA56187A
MA56187A MA056187A MA56187A MA56187A MA 56187 A MA56187 A MA 56187A MA 056187 A MA056187 A MA 056187A MA 56187 A MA56187 A MA 56187A MA 56187 A MA56187 A MA 56187A
Authority
MA
Morocco
Prior art keywords
treatments
hereditary angioedema
angioedema
hereditary
Prior art date
Application number
MA056187A
Other languages
English (en)
Other versions
MA56187B1 (fr
Inventor
Edward Paul Feener
Andreas Maetzel
Sally Louise Marsh
Michael David Smith
Christopher Martyn Yea
Original Assignee
Kalvista Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kalvista Pharmaceuticals Ltd filed Critical Kalvista Pharmaceuticals Ltd
Publication of MA56187A publication Critical patent/MA56187A/fr
Publication of MA56187B1 publication Critical patent/MA56187B1/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
MA56187A 2019-07-15 2020-06-15 Traitements de l'angio-oedème héréditaire MA56187B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1910116.1A GB201910116D0 (en) 2019-07-15 2019-07-15 Treatments of hereditary angioedema
PCT/GB2020/051439 WO2020249977A1 (fr) 2019-06-14 2020-06-15 Traitements de l'angio-oedème héréditaire

Publications (2)

Publication Number Publication Date
MA56187A true MA56187A (fr) 2022-04-20
MA56187B1 MA56187B1 (fr) 2023-09-27

Family

ID=67700145

Family Applications (1)

Application Number Title Priority Date Filing Date
MA56187A MA56187B1 (fr) 2019-07-15 2020-06-15 Traitements de l'angio-oedème héréditaire

Country Status (34)

Country Link
US (1) US20220218680A1 (fr)
EP (2) EP4282474A3 (fr)
JP (3) JP7356518B2 (fr)
KR (1) KR102748728B1 (fr)
CN (1) CN114126612A (fr)
AR (1) AR119158A1 (fr)
AU (1) AU2020293614B2 (fr)
BR (1) BR112021024664A2 (fr)
CA (1) CA3142218A1 (fr)
CL (2) CL2021003244A1 (fr)
DK (1) DK3982960T3 (fr)
EA (1) EA202193019A1 (fr)
ES (1) ES2956471T3 (fr)
FI (1) FI3982960T3 (fr)
GB (1) GB201910116D0 (fr)
HR (1) HRP20230696T1 (fr)
HU (1) HUE063163T2 (fr)
IL (1) IL288615A (fr)
LT (1) LT3982960T (fr)
MA (1) MA56187B1 (fr)
MD (1) MD3982960T2 (fr)
MX (1) MX2021014557A (fr)
MY (1) MY205687A (fr)
PH (1) PH12021552966A1 (fr)
PL (1) PL3982960T3 (fr)
PT (1) PT3982960T (fr)
RS (1) RS64412B1 (fr)
SG (1) SG11202113304YA (fr)
SI (1) SI3982960T1 (fr)
SM (1) SMT202300261T1 (fr)
TW (1) TW202112370A (fr)
UA (1) UA129869C2 (fr)
WO (1) WO2020249977A1 (fr)
ZA (1) ZA202110685B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201609607D0 (en) 2016-06-01 2016-07-13 Kalvista Pharmaceuticals Ltd Polymorphs of N-(3-Fluoro-4-methoxypyridin-2-yl)methyl)-3-(methoxymethyl)-1-({4-((2-oxopy ridin-1-yl)methyl)phenyl}methyl)pyrazole-4-carboxamide and salts
GB201719881D0 (en) 2017-11-29 2018-01-10 Kalvista Pharmaceuticals Ltd Solid forms of plasma kallikrein inhibitor and salts thereof
GB201910116D0 (en) * 2019-07-15 2019-08-28 Kalvista Pharmaceuticals Ltd Treatments of hereditary angioedema
EP4010333A1 (fr) 2019-08-09 2022-06-15 Kalvista Pharmaceuticals Limited Inhibiteurs de la kallicréine plasmatique
EP4232031A1 (fr) * 2020-10-23 2023-08-30 Kalvista Pharmaceuticals Limited Traitements de l'oedème de quincke
JP2024505596A (ja) * 2021-02-09 2024-02-06 カルビスタ・ファーマシューティカルズ・リミテッド 遺伝性血管性浮腫の治療
EP4480545A3 (fr) 2022-04-27 2025-02-26 Kalvista Pharmaceuticals Limited Formulations d'un inhibiteur de kallicréine plasmatique
CN116003386B (zh) * 2022-11-20 2024-03-26 药康众拓(北京)医药科技有限公司 一种氘代n-苄基吡啶酮吡唑甲酰胺类化合物、药物组合物和用途
WO2025172692A1 (fr) 2024-02-13 2025-08-21 Kalvista Pharmaceuticals Limited Sebetralstat à administrer par voie orale pour le traitement d'une attaque d'angioedème héréditaire
WO2025172693A1 (fr) 2024-02-13 2025-08-21 Kalvista Pharmaceuticals Limited Sebetralstat oral pour le traitement d'un épisode d'angio-œdème héréditaire
WO2026003532A1 (fr) 2024-06-28 2026-01-02 Kalvista Pharmaceuticals Limited Sébetralstat pour le traitement de l'anxiété associée à un angioedème héréditaire

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5187157A (en) 1987-06-05 1993-02-16 Du Pont Merck Pharmaceutical Company Peptide boronic acid inhibitors of trypsin-like proteases
GB9019558D0 (en) 1990-09-07 1990-10-24 Szelke Michael Enzyme inhibitors
SE9301911D0 (sv) 1993-06-03 1993-06-03 Ab Astra New peptide derivatives
US5589467A (en) 1993-09-17 1996-12-31 Novo Nordisk A/S 2,5',N6-trisubstituted adenosine derivatives
GB0205527D0 (en) 2002-03-08 2002-04-24 Ferring Bv Inhibitors
US7429604B2 (en) 2004-06-15 2008-09-30 Bristol Myers Squibb Company Six-membered heterocycles useful as serine protease inhibitors
WO2008016883A2 (fr) 2006-07-31 2008-02-07 Activesite Pharmaceuticals, Inc. Inhibiteurs de kallicréine plasmatique
DE102006050672A1 (de) 2006-10-24 2008-04-30 Curacyte Discovery Gmbh Hemmstoffe des Plasmins und des Plasmakallikreins
JP2013121919A (ja) 2010-03-25 2013-06-20 Astellas Pharma Inc 血漿カリクレイン阻害剤
WO2012004678A2 (fr) 2010-07-07 2012-01-12 The Medicines Company (Leipzig) Gmbh Inhibiteurs de la sérine protéase
EP2595986A2 (fr) 2010-07-14 2013-05-29 Addex Pharma SA Nouveaux dérivés de 2-amino-4-pyrazolyl-thiazole et leur utilisation en tant que modulateurs allostériques des récepteurs métabotropiques du glutamate
US9290485B2 (en) 2010-08-04 2016-03-22 Novartis Ag N-((6-amino-pyridin-3-yl)methyl)-heteroaryl-carboxamides
GB2494851A (en) 2011-07-07 2013-03-27 Kalvista Pharmaceuticals Ltd Plasma kallikrein inhibitors
GB201300304D0 (en) 2013-01-08 2013-02-20 Kalvista Pharmaceuticals Ltd Benzylamine derivatives
EP2999697B1 (fr) 2013-05-23 2017-04-19 Kalvista Pharmaceuticals Limited Dérivés hétérocycliques
EP2815749A1 (fr) * 2013-06-20 2014-12-24 IP Gesellschaft für Management mbH Forme solide de 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione ayant un réseau de diffraction de rayons X spécifique
EP2886107A1 (fr) * 2013-12-17 2015-06-24 ObsEva S.A. Formules orales de dérivés de pyrrolydine
GB201421083D0 (en) 2014-11-27 2015-01-14 Kalvista Pharmaceuticals Ltd Enzyme inhibitors
GB201721515D0 (en) * 2017-12-21 2018-02-07 Kalvista Pharmaceuticals Ltd Dosage forms comprising a plasma kallikrein inhibtor
GB201910116D0 (en) 2019-07-15 2019-08-28 Kalvista Pharmaceuticals Ltd Treatments of hereditary angioedema

Also Published As

Publication number Publication date
KR102748728B1 (ko) 2024-12-30
GB201910116D0 (en) 2019-08-28
TW202112370A (zh) 2021-04-01
ZA202110685B (en) 2024-06-26
CL2021003244A1 (es) 2022-09-30
JP2025124716A (ja) 2025-08-26
SG11202113304YA (en) 2021-12-30
JP7356518B2 (ja) 2023-10-04
AU2020293614B2 (en) 2024-08-15
CL2023000639A1 (es) 2023-10-30
FI3982960T3 (fi) 2023-08-29
SI3982960T1 (sl) 2023-10-30
MD3982960T2 (ro) 2023-12-31
LT3982960T (lt) 2023-08-25
MX2021014557A (es) 2022-01-11
AR119158A1 (es) 2021-12-01
PH12021552966A1 (en) 2022-07-25
KR20220024220A (ko) 2022-03-03
UA129869C2 (uk) 2025-08-27
RS64412B1 (sr) 2023-09-29
CA3142218A1 (fr) 2020-12-17
PT3982960T (pt) 2023-09-26
NZ782935A (en) 2025-02-28
HUE063163T2 (hu) 2023-12-28
IL288615A (en) 2022-02-01
AU2020293614A1 (en) 2022-01-27
EP4282474A3 (fr) 2024-02-14
JP2023166406A (ja) 2023-11-21
EA202193019A1 (ru) 2022-03-24
CN114126612A (zh) 2022-03-01
MA56187B1 (fr) 2023-09-27
MY205687A (en) 2024-11-06
JP2022536287A (ja) 2022-08-15
SMT202300261T1 (it) 2023-09-06
BR112021024664A2 (pt) 2022-05-31
PL3982960T3 (pl) 2024-01-15
WO2020249977A1 (fr) 2020-12-17
EP3982960B1 (fr) 2023-06-28
EP4282474A2 (fr) 2023-11-29
DK3982960T3 (da) 2023-08-21
HRP20230696T1 (hr) 2023-10-13
US20220218680A1 (en) 2022-07-14
JP7688078B2 (ja) 2025-06-03
ES2956471T3 (es) 2023-12-21
EP3982960A1 (fr) 2022-04-20

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