MA56463A - Plate-forme d'administration non parentérale d'agent thérapeutique d'arthrospira platensis - Google Patents

Plate-forme d'administration non parentérale d'agent thérapeutique d'arthrospira platensis

Info

Publication number
MA56463A
MA56463A MA056463A MA56463A MA56463A MA 56463 A MA56463 A MA 56463A MA 056463 A MA056463 A MA 056463A MA 56463 A MA56463 A MA 56463A MA 56463 A MA56463 A MA 56463A
Authority
MA
Morocco
Prior art keywords
therapeutic agent
agent administration
administration platform
arthrospira platensis
parenteral therapeutic
Prior art date
Application number
MA056463A
Other languages
English (en)
Inventor
Mesfin Gewe
Benjamin Jester
James Roberts
Tracy Saveria
Michael Tasch
Original Assignee
Lumen Bioscience Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lumen Bioscience Inc filed Critical Lumen Bioscience Inc
Publication of MA56463A publication Critical patent/MA56463A/fr

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/742Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/748Cyanobacteria, i.e. blue-green bacteria or blue-green algae, e.g. spirulina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/002Protozoa antigens
    • A61K39/015Hemosporidia antigens, e.g. Plasmodium antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10RNA viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10RNA viruses
    • C07K16/102Coronaviridae (F)
    • C07K16/104Severe acute respiratory syndrome coronavirus 2 [SARS‐CoV‐2]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203Gram-negative bacteria
    • C07K16/121Helicobacter (G); Campylobacter (G)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267Gram-positive bacteria
    • C07K16/1282Clostridium (G)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/12Unicellular algae; Culture media therefor
    • C12N1/125Unicellular algae isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507Comprising a combination of two or more separate antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/517Plant cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/542Mucosal route oral/gastrointestinal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/543Mucosal route intranasal
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/22Immunoglobulins specific features characterized by taxonomic origin from camelids, e.g. camel, llama or dromedary
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/569Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94Stability, e.g. half-life, pH, temperature or enzyme-resistance
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Mycology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
MA056463A 2019-07-03 2020-07-02 Plate-forme d'administration non parentérale d'agent thérapeutique d'arthrospira platensis MA56463A (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962870478P 2019-07-03 2019-07-03
US201962937995P 2019-11-20 2019-11-20
US201962943075P 2019-12-03 2019-12-03

Publications (1)

Publication Number Publication Date
MA56463A true MA56463A (fr) 2022-05-11

Family

ID=74100810

Family Applications (1)

Application Number Title Priority Date Filing Date
MA056463A MA56463A (fr) 2019-07-03 2020-07-02 Plate-forme d'administration non parentérale d'agent thérapeutique d'arthrospira platensis

Country Status (9)

Country Link
US (1) US12503682B2 (fr)
EP (1) EP3994152A4 (fr)
JP (2) JP7770675B2 (fr)
CN (1) CN114341165A (fr)
AU (1) AU2020298626A1 (fr)
CA (1) CA3143735A1 (fr)
IL (1) IL289420A (fr)
MA (1) MA56463A (fr)
WO (1) WO2021003456A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12447202B2 (en) 2018-05-17 2025-10-21 Lumen Bioscience, Inc. Arthrospira platensis oral vaccine delivery platform
WO2020018586A1 (fr) 2018-07-16 2020-01-23 Lumen Bioscience, Inc. Phycobiliprotéines thermostables produites dans la spiruline
US12441783B2 (en) 2019-01-07 2025-10-14 Bactolife Aps Pathogen binding proteins
WO2021003456A1 (fr) 2019-07-03 2021-01-07 Lumen Bioscience, Inc. Plate-forme d'administration non parentérale d'agent thérapeutique d'arthrospira platensis
EP4267185A4 (fr) * 2020-12-23 2024-10-30 Lumen Bioscience, Inc. Constructions comprenant des anticorps vhh à domaine unique dirigé contre le sars-cov-2
US20250136669A1 (en) * 2021-12-15 2025-05-01 Teikyo Heisei University Vhh antibody
WO2024238678A2 (fr) * 2023-05-15 2024-11-21 Lumen Bioscience, Inc. Agents méthanolytiques et leurs méthodes d'utilisation
WO2025058962A1 (fr) * 2023-09-11 2025-03-20 Absci Corporation Procédés à haut rendement pour caractérisation cinétique, quantification et optimisation d'anticorps et d'expression de fragments d'anticorps dans des bactéries
WO2025125852A1 (fr) * 2023-12-11 2025-06-19 Abdali Nargess Vaccin oral contre la covid-19
WO2025240494A1 (fr) 2024-05-13 2025-11-20 Lumen Bioscience, Inc. Compositions de leptine et leurs procédés de fabrication et d'utilisation pour une perte de poids et/ou un maintien du poids

Family Cites Families (194)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4751180A (en) 1985-03-28 1988-06-14 Chiron Corporation Expression using fused genes providing for protein product
US4935233A (en) 1985-12-02 1990-06-19 G. D. Searle And Company Covalently linked polypeptide cell modulators
US4873192A (en) 1987-02-17 1989-10-10 The United States Of America As Represented By The Department Of Health And Human Services Process for site specific mutagenesis without phenotypic selection
FR2646438B1 (fr) 1989-03-20 2007-11-02 Pasteur Institut Procede de remplacement specifique d'une copie d'un gene present dans le genome receveur par l'integration d'un gene different de celui ou se fait l'integration
US5429939A (en) 1989-04-21 1995-07-04 Kirin Beer Kabushiki Kaisha DNA sequences useful for the synthesis of carotenoids
JP2950888B2 (ja) 1989-04-21 1999-09-20 麒麟麦酒株式会社 カロチノイドの合成に有用なdna鎖
EP0393690B1 (fr) 1989-04-21 1995-03-29 Kirin Beer Kabushiki Kaisha Séquences de DNA utilisables dans la synthèse de caroténoides
US5684238A (en) 1990-03-02 1997-11-04 Amoco Corporation Biosynthesis of zeaxanthin and glycosylated zeaxanthin in genetically engineered hosts
JPH06253863A (ja) 1993-02-26 1994-09-13 Agency Of Ind Science & Technol スピルリナの形質転換方法およびスピルリナの形質転換体
US5661017A (en) 1993-09-14 1997-08-26 Dunahay; Terri Goodman Method to transform algae, materials therefor, and products produced thereby
DE69433969T2 (de) 1993-12-27 2005-08-11 Kirin Beer K.K. Dna - kette zur synthese von xanthophyll und prozess zur herstellung von xanthophyll
DE69526842T3 (de) 1994-08-23 2005-10-27 Kirin Beer K.K. Ketogruppe-einführendes enzym, dafür kodierende dna und verfahren zur herstellung von ketocarotenoid
US6342389B1 (en) 1995-04-10 2002-01-29 Roger S. Cubicciotti Modified phycobilisomes and uses therefore
ES2216027T3 (es) 1995-06-09 2004-10-16 Dsm Ip Assets B.V. Produccion de carotenoides fermentativos.
EP0872554B1 (fr) 1996-12-02 2003-06-11 F. Hoffmann-La Roche Ag Production améliorée de caroténoides par fermentation
EP1854889A1 (fr) 1997-02-19 2007-11-14 Enol Energy Inc. Cyanobactéries modifiées génétiquement pour la production d'éthanol
CN1067719C (zh) 1997-07-10 2001-06-27 中山大学 外源基因转化螺旋藻的方法
JP3874897B2 (ja) 1997-08-07 2007-01-31 麒麟麦酒株式会社 β−カロチンハイドロキシラーゼ遺伝子およびその使用
JPH1156360A (ja) 1997-08-27 1999-03-02 Iwate Pref Gov エレクトロポレーションによる遺伝子導入法
JP3032841B2 (ja) 1997-12-02 2000-04-17 農林水産省果樹試験場長 β−カロテンハイドロキシラーゼ遺伝子
BR0007128A (pt) 1998-06-02 2001-07-17 Univ Maryland Genes para a biossìntese e metabolismo de carotenoides e método de aplicação dos mesmos
FR2784688B1 (fr) 1998-10-20 2002-12-13 Univ Grenoble 1 SEQUENCE D'ADNc DECRITE PAR SEQ ID N°1 TRANSCRIVANT UN ARNm CODANT POUR L'OXYDASE TERMINALE ASSOCIEE A LA BIOSYNTHESE DES CAROTENOIDES
MXPA01009577A (es) 1999-04-01 2003-07-21 Basf Plant Science Gmbh Una nueva clase de enzimas en la trayectoria biosintetica para la produccion de triacilglicerol y moleculas de adn recombinante que codifican estan enzimas.
US7157619B1 (en) 1999-08-30 2007-01-02 Monsanto Technology, L.L.C. Plant sterol acyltransferases
US6649376B1 (en) 1999-12-21 2003-11-18 The Regents Of The University Of California Multifunctional recombinant phycobiliprotein-based fluorescent constructs and phycobilisome display
US7033806B2 (en) 2000-06-08 2006-04-25 The Regents Of The University Of California HY2 family of bilin reductases
US6818424B2 (en) 2000-09-01 2004-11-16 E. I. Du Pont De Nemours And Company Production of cyclic terpenoids
US20050260699A1 (en) 2000-11-22 2005-11-24 Desouza Mervyn L Carotenoid biosynthesis
US20040078846A1 (en) 2002-01-25 2004-04-22 Desouza Mervyn L. Carotenoid biosynthesis
US20050003474A1 (en) 2001-01-26 2005-01-06 Desouza Mervyn L. Carotenoid biosynthesis
US6887688B2 (en) 2001-05-29 2005-05-03 The Regents Of The University Of California Light controlled gene expression utilizing heterologous phytochromes
US7252964B2 (en) 2001-06-12 2007-08-07 Institut De Recherche Pour Le Developpement (I.R.D.) Isolated carotenoid biosynthesis gene cluster involved in canthaxanthin production and applications thereof
US20090215179A1 (en) 2001-07-20 2009-08-27 Transalgae Transgenically preventing establishment and spread of transgenic algae in natural ecosystems
US20030148319A1 (en) 2001-08-15 2003-08-07 Brzostowicz Patricia C. Genes encoding carotenoid compounds
US20040077068A1 (en) 2001-09-04 2004-04-22 Brzostowicz Patricia C. Carotenoid production from a single carbon substrate
BR0213496A (pt) 2001-10-23 2004-12-07 Japan Tobacco Inc Métodos de elevar a velocidade de fotossìntese de planta melhorando a piruvato fosfato dicinase
US7314974B2 (en) 2002-02-21 2008-01-01 Monsanto Technology, Llc Expression of microbial proteins in plants for production of plants with improved properties
US7118896B2 (en) 2002-03-01 2006-10-10 Monsanto Technology, L.L.C. Methods and compositions for modification of lipid biosynthesis
US7223909B2 (en) 2002-03-21 2007-05-29 Ball Horticultural 4-ketocarotenoids in flower petals
JP4415138B2 (ja) 2002-05-08 2010-02-17 独立行政法人産業技術総合研究所 義務教育、理科実験においても使用可能な大腸菌等への遺伝子導入手法
SE0201581D0 (sv) 2002-05-29 2002-05-29 Scandinavian Biotechnology Res New improved acyltransferase
AU2003251604A1 (en) * 2002-06-26 2004-01-19 F. C. Thomas Allnutt Viruses and virus-like particles for multiple antigen and target display
WO2004018694A2 (fr) 2002-08-20 2004-03-04 Sungene Gmbh & Co. Kgaa Procede d'obtention de cetocarotinoides dans des organismes genetiquement modifies
AU2003258622A1 (en) 2002-08-20 2004-03-11 Sungene Gmbh And Co. Kgaa Method for the production of $g(b)-carotinoids
EP1546314A1 (fr) 2002-09-27 2005-06-29 DSM IP Assets B.V. Gene bhyd
JP2006500055A (ja) 2002-09-27 2006-01-05 ディーエスエム アイピー アセッツ ビー.ブイ. ファフィア属によるゼアキサンチンの製造方法
US7232665B2 (en) 2002-12-19 2007-06-19 E. I. Du Pont De Nemours And Company Mutations affecting carotenoid production
US20040219629A1 (en) 2002-12-19 2004-11-04 Qiong Cheng Increasing carotenoid production in bacteria via chromosomal integration
US7291482B2 (en) 2002-12-20 2007-11-06 E.I. Du Pont De Nemours And Company Mutations affecting plasmid copy number
DE10300649A1 (de) 2003-01-09 2004-07-22 Basf Ag Verfahren zur Herstellung von Ketocarotinoiden durch Kultivierung von genetisch veränderten Organismen
RU2005125072A (ru) 2003-01-09 2006-06-10 БАСФ Акциенгезельшафт (DE) Способ получения каротиноидов или их предшественников с помощью генно-инженерно видоизмененных микроорганизмов семейства blakeslea, полученные указанным способом каротиноиды или их предшественники и их применение
RU2005125073A (ru) 2003-01-09 2006-06-10 БАСФ Акциенгезельшафт (DE) Пособ генно-инженерного видоизменения микроорганизмов семейства blakeslea, родственных микроорганизмов и их применение
EP1620537B1 (fr) 2003-03-14 2012-10-24 Cellectis SA Procede d'electroporation ex vivo a grand volume
CA2521075A1 (fr) 2003-03-31 2004-10-14 Algentech Gene intervenant dans la biosynthese d'un carotenoide et micro-organisme marin, le paracoccus haeundaensis, produisant ce carotenoide
US7786349B2 (en) 2003-04-09 2010-08-31 Bayer Bioscience N.V. Methods and means for increasing the tolerance of plants to stress conditions
EP2361977A1 (fr) 2003-04-15 2011-08-31 BASF Plant Science GmbH Séquences d'acides nucléiques codant pour des protéines associées à une réponse au stress abiotique, et cellules végétales transgéniques transformées par les mêmes
US7070952B2 (en) 2003-05-07 2006-07-04 E. I. Du Pont Nemours And Company Genes encoding carotenoid compounds
US7064196B2 (en) 2003-05-20 2006-06-20 E. I. Du Pont De Nemours And Company Genes encoding carotenoid compounds
US6929928B2 (en) 2003-06-12 2005-08-16 E. I. Du Pont De Nemours And Company Genes encoding carotenoid compounds
EP1667732B1 (fr) 2003-09-29 2010-04-21 Nitto Denko Corporation Polyacetals biodegradables pour administration de polynucleotides in vivo
CN1528902A (zh) * 2003-10-02 2004-09-15 广东梅县梅雁蓝藻有限公司 用螺旋藻同源重组和表达人体基因的方法
DE602004025734D1 (de) 2003-11-18 2010-04-08 Kirin Holdings Kk Neues carotenoidhydroxylasegen, verfahren zur herstellung von hydroxyliertem carotenoid und neues geranylgeranylpyrophosphatsynthasegen
US20060057726A1 (en) 2003-12-03 2006-03-16 Sharpe Pamela L Method for the positive selection of chromosomal mutations in C1 metabolizing bacteria via homologous recombination
WO2005062867A2 (fr) 2003-12-19 2005-07-14 E.I. Dupont De Nemours And Company Nouvelles cetolases de carotenoide
WO2005062923A2 (fr) 2003-12-24 2005-07-14 Massachusetts Institute Of Technology Cibles geniques pour une meilleure production de carotenoides
US7741070B2 (en) 2003-12-24 2010-06-22 Massachusetts Institute Of Technology Gene targets for enhanced carotenoid production
FR2864968B1 (fr) 2004-01-09 2007-10-05 Inst Rech Developpement Ird Procede de production de carotenoides et bacteries mises en oeuvre
US20060041961A1 (en) 2004-03-25 2006-02-23 Abad Mark S Genes and uses for pant improvement
US7063957B2 (en) 2004-03-26 2006-06-20 The University Of Hong Kong Methods for production of astaxanthin from the green microalgae Chlorella in dark-heterotrophic cultures
US7999151B2 (en) 2004-06-04 2011-08-16 Kirin Holdings Kabushiki Kaisha Method of producing astaxanthin or metabolic product thereof by using carotenoid ketolase and carotenoid hydroxylase genes
EP1753870A4 (fr) 2004-06-08 2009-07-08 Du Pont Genes de cetolase carotenoide a rendement cetocarotenoide ameliore
US20050281839A1 (en) * 2004-06-18 2005-12-22 Amha Belay Spirulina composition and antiallergic food
US7091031B2 (en) 2004-08-16 2006-08-15 E. I. Du Pont De Nemours And Company Carotenoid hydroxylase enzymes
JP2006075097A (ja) 2004-09-10 2006-03-23 Tadashi Matsunaga カロテノイド生産能を有する形質転換体及びカロテノイドの生産方法
US7572451B2 (en) 2004-10-25 2009-08-11 Cytos Biotechnology Ag Gastric inhibitory polypeptide (GIP) antigen arrays and uses thereof
US20060099710A1 (en) 2004-11-10 2006-05-11 Donnelly Mark I Vector for improved in vivo production of proteins
JP4799895B2 (ja) 2004-12-15 2011-10-26 電源開発株式会社 カロチノイド色素、スフィンゴ糖脂質、ユビキノンq−10の生産方法
US20080148432A1 (en) 2005-12-21 2008-06-19 Mark Scott Abad Transgenic plants with enhanced agronomic traits
US7074604B1 (en) 2004-12-29 2006-07-11 E. I. Du Pont De Nemours And Company Bioproduction of astaxanthin using mutant carotenoid ketolase and carotenoid hydroxylase genes
RU2005101110A (ru) 2005-01-19 2006-06-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) Способ получения l-аминокислот с использованием бактерии семейства enterobacteriaceae, в которой разрушен путь биосинтеза гликогена
WO2006096392A2 (fr) 2005-03-04 2006-09-14 Diversa Corporation Enzymes intervenant dans les voies de synthese biologique d'astaxanthines, de carotenoides et d'isoprenoides, genes codant ces enzymes et procedes de production et d'utilisation de celles-ci
WO2006108226A1 (fr) * 2005-04-12 2006-10-19 The University Of Queensland Systeme de delivrance d’un vaccin
EP1928227A4 (fr) 2005-08-30 2009-05-20 Monsanto Technology Llc Plantes transgeniques a traits agronomiques ameliores
WO2007035579A2 (fr) 2005-09-15 2007-03-29 The Regents Of The University Of California Procédés et compositions pour la production de gaz méthane
US7217537B2 (en) 2005-09-15 2007-05-15 E. I. Du Pont De Nemours And Company Method to increase carotenoid production in a microbial host cell by down-regulating glycogen synthase
US20070065901A1 (en) 2005-09-19 2007-03-22 Dicosimo Deana J Process for chromosomal expression of foreign genes in the PAPS reductase (cysH) region of a methylotrophic microbial host cell
US20070065902A1 (en) 2005-09-19 2007-03-22 Dicosimo Deana J Process for chromosomal expression of foreign genes in the fliC region of a methylotrophic microbial host cell
US20070065900A1 (en) 2005-09-19 2007-03-22 Dicosimo Deana J Process for chromosomal expression of foreign genes in the cytochrome-C peroxidase (cytCP) region of a methylotrophic microbial host cell
US20070065903A1 (en) 2005-09-19 2007-03-22 Dicosimo Deana J Process for chromosomal expression of foreign genes in the hsdM region of a methylotrophic microbial host cell
US8883969B2 (en) 2005-10-28 2014-11-11 Tosoh Corporation Method for production of carotenoid-synthesizing microorganism and method for production of carotenoid
KR100788479B1 (ko) 2005-11-25 2007-12-24 부경대학교 산학협력단 카로티노이드 생합성 유전자를 이용한 대장균으로부터아스타잔틴의 생산
GB0524873D0 (en) 2005-12-06 2006-01-11 New Royal Holloway & Bedford Bacterial production of carotenoids
US8030022B2 (en) 2005-12-06 2011-10-04 Tosoh Corporation Microorganism and method for producing carotenoid using it
US7393671B2 (en) 2006-03-30 2008-07-01 E.I. Du Pont De Nemours And Company Mutant carotenoid ketolases
US7422873B2 (en) 2006-03-31 2008-09-09 E.I. Du Pont De Nemours And Company Mutant carotenoid ketolase
TW200811098A (en) 2006-04-27 2008-03-01 Astrazeneca Ab Chemical compounds
CN1843150A (zh) * 2006-05-08 2006-10-11 陈晓雁 螺旋藻酶解生产工艺
MX2008014603A (es) 2006-05-19 2009-02-06 Ls9 Inc Produccion de acidos grasos y derivados de los mismos.
US8110670B2 (en) 2006-05-19 2012-02-07 Ls9, Inc. Enhanced production of fatty acid derivatives
WO2008021543A2 (fr) 2006-08-17 2008-02-21 Monsanto Technology, Llc Plantes transgéniques à caractères agronomiques renforcés
US20080107652A1 (en) 2006-08-25 2008-05-08 Science & Technology Corporation @ University Of New Mexico Stc.Unm Methods and compositions for control of disease in aquaculture
US20080124755A1 (en) 2006-10-12 2008-05-29 Michael Tai-Man Louie Biosynthesis of beta-cryptoxanthin in microbial hosts using an Arabidopsis thaliana beta-carotene hydroxylase gene
BRPI0717474A2 (pt) 2006-10-20 2014-03-11 Arizona Board Of Regentes For And On Behalf Of Arizona State University Cianobactéria modificada
KR100845582B1 (ko) 2006-11-09 2008-07-11 부경대학교 산학협력단 이소프레노이드와 카로티노이드 생합성 유전자로 형질전환된 대장균 및 이를 이용한 아스타잔틴의 대량 생산방법
US8846374B2 (en) 2006-12-12 2014-09-30 E I Du Pont De Nemours And Company Carotenoid production in a recombinant oleaginous yeast
US8349326B2 (en) * 2007-02-20 2013-01-08 Tufts University Methods and systems for multi-antibody therapies
US9023352B2 (en) * 2007-02-20 2015-05-05 Tufts University Methods, compositions and kits for treating a subject using a recombinant heteromultimeric neutralizing binding protein
CN101680009B (zh) 2007-03-28 2017-02-22 Reg生命科学有限责任公司 提高脂肪酸衍生物的产量
US20100199548A1 (en) 2007-07-06 2010-08-12 Ls9, Inc. Systems and methods for the production of fatty esters
WO2009010826A2 (fr) 2007-07-13 2009-01-22 Ocean Nutrition Canada Ltd. Nouveaux gènes et procédés de production de caroténoïdes
US20090191599A1 (en) 2007-09-10 2009-07-30 Joule Biotechnologies, Inc. Engineered light-harvesting organisms
US8313934B2 (en) 2007-09-27 2012-11-20 Ls9, Inc. Reduction of the toxic effect of impurities from raw materials by extractive fermentation
CN101173214B (zh) 2007-10-30 2010-05-19 中国科学院南海海洋研究所 雨生红球藻的虾青素高产突变株
KR20090046376A (ko) 2007-11-06 2009-05-11 부경대학교 산학협력단 카로티노이드 생합성 유전자로 형질 전환된 효모 및 이를이용한 아스타잔틴의 대량 생산 방법
EP2217695A2 (fr) 2007-11-10 2010-08-18 Joule Unlimited, Inc. Organismes hyperphotosynthétiques
US8815567B2 (en) 2007-11-30 2014-08-26 E I Du Pont De Nemours And Company Coenzyme Q10 production in a recombinant oleaginous yeast
AU2008335089B2 (en) 2007-12-11 2014-06-26 Synthetic Genomics, Inc. Secretion of fatty acids by photosynthetic microorganisms
US20090155864A1 (en) 2007-12-14 2009-06-18 Alan Joseph Bauer Systems, methods, and devices for employing solar energy to produce biofuels
US8367379B2 (en) 2008-01-03 2013-02-05 Proterro, Inc. Transgenic photosynthetic microorganisms and photobioreactor
TW200934872A (en) 2008-02-05 2009-08-16 Echem Hightech Co Ltd A strain of genetically reengineered escherichia coli for biosynthesis of high yield carotenoids after mutation screening
WO2009098089A2 (fr) 2008-02-08 2009-08-13 Kerstin Baier Cellules hôtes productrices d’éthanol, photoautotrophes, génétiquement modifiées, procédé de production des cellules hôtes, de constructions pour la transformation des cellules hôtes, procédé de recherche d’une propriété de croissance souhaitée chez une souche photoautotrophe et procédé de production d’éthanol utilisant les cellules hôtes
CN102084002B (zh) 2008-03-03 2014-09-10 Abbvie公司 用于转化酵母的方法
US7981647B2 (en) 2008-03-03 2011-07-19 Joule Unlimited, Inc. Engineered CO2 fixing microorganisms producing carbon-based products of interest
CN105112454B (zh) 2008-05-16 2017-01-18 Reg生命科学有限责任公司 产生碳氢化合物的方法和组合物
WO2010019813A2 (fr) 2008-08-13 2010-02-18 Sapphire Energy, Inc. Production d'acides gras par organismes photosynthétiques génétiquement modifiés
WO2010021711A1 (fr) 2008-08-18 2010-02-25 Ls9, Inc. Systèmes et procédés de production d'esters gras mixtes
WO2010027516A2 (fr) 2008-09-05 2010-03-11 Jonathan Gressel Prévention de manière transgénique de l’établissement et de la propagation d’algues transgéniques dans des écosystèmes naturels
US20110218354A1 (en) 2008-09-19 2011-09-08 President And Fellows Of Harvard College Photoautotrophic Adipogenesis Technology (Phat)
EA201100527A1 (ru) 2008-09-26 2011-10-31 Юсб Фарма С.А. Биологические продукты
CA2738938C (fr) 2008-10-07 2019-04-30 Ls9, Inc. Procede et compositions pour produire des aldehydes gras
US8394621B2 (en) 2008-10-23 2013-03-12 Matrix Genetrics, LLC Modified photosynthetic microorganisms for producing triglycerides
CA3041892C (fr) 2008-10-28 2022-03-15 REG Life Sciences, LLC Procedes permettant de produire un alcool gras dans une cellule hote
WO2010062707A1 (fr) 2008-10-30 2010-06-03 Joule Unlimited, Inc. Procédés et compositions pour produire des produits d’intérêt à base de carbone dans des micro-organismes
KR20100051306A (ko) 2008-11-07 2010-05-17 부경대학교 산학협력단 파라코커스 해운댄시스의 돌연변이와 스트레스 처리에 의한아스타잔틴 생성량 증가 방법
CN105647842A (zh) 2008-12-23 2016-06-08 Reg生命科学有限责任公司 硫酯酶相关的方法和组合物
EP2379706A1 (fr) 2008-12-23 2011-10-26 Targeted Growth, Inc. Micro-organismes photosynthétiques modifiés à glycogène réduit et leur utilisation dans la production de produits à base de carbone
WO2010078584A1 (fr) 2009-01-05 2010-07-08 Arizona Board Of Regents Cyanobactérie produisant des lipides neutres
BRPI1008958A2 (pt) 2009-03-11 2015-09-01 Sapphire Energy Inc Produção de biocombustível em procariotas e eucariotas
WO2010118410A1 (fr) 2009-04-10 2010-10-14 Ls9, Inc. Production de dérivés d'acide gras
BRPI1015313B1 (pt) 2009-04-27 2021-06-01 Genomatica, Inc. Método fermentativo para produzir um éster de ácido graxo empregando um microorganismo geneticamente modificado e método para a produção de ésteres de ácidos graxos
CA2760326A1 (fr) 2009-05-13 2010-11-18 Basf Plant Science Company Gmbh Acyltransferases et leurs utilisations dans la production d'acide gras
US8956834B2 (en) 2009-06-29 2015-02-17 Synthetic Genomics, Inc. Acyl-ACP thioesterase genes and uses therefor
WO2011008535A1 (fr) 2009-06-30 2011-01-20 Codexis, Inc. Production d'alcools gras avec des acyl-coa réductases (far) formant des alcools gras
US7794969B1 (en) 2009-07-09 2010-09-14 Joule Unlimited, Inc. Methods and compositions for the recombinant biosynthesis of n-alkanes
US9359623B2 (en) 2009-07-24 2016-06-07 The Regents Of The University Of California Methods and compositions for the production of fatty acids in photosynthetic prokaryotic microorganisms
WO2011018116A1 (fr) 2009-08-13 2011-02-17 Algenol Biofuels Inc. Cellules hôtes produisant de l'éthanol phototrophes améliorées du point de vue métabolique, procédé de production des cellules hôtes, produits de synthèse pour la transformation des cellules hôtes et procédé de production d'éthanol utilisant les cellules hôtes
WO2011029013A2 (fr) 2009-09-04 2011-03-10 President And Fellows Of Harvard College Obtention de produits biologiques secrétés par microbes photosynthétiques
CN105969710A (zh) 2009-09-25 2016-09-28 Reg生命科学有限责任公司 脂肪酸衍生物的产生
JP5660543B2 (ja) 2009-10-27 2015-01-28 電源開発株式会社 新規細菌株、培養物及びカロテノイド色素の製造方法
WO2011059745A1 (fr) 2009-10-28 2011-05-19 The Arizona Board Of Regents For And On Behalf Of Arizona State University Bactérie pour la production d'acides gras
JP2013511261A (ja) 2009-11-18 2013-04-04 マリー ゴールバーン シーオー−オペレイティブ シーオー.リミテッド 組換え微生物
US8530221B2 (en) 2010-01-14 2013-09-10 Ls9, Inc. Production of branched chain fatty acids and derivatives thereof in recombinant microbial cells
WO2011127118A1 (fr) 2010-04-06 2011-10-13 Algenetix, Inc. Procédés de production d'huile dans des organismes non végétaux
WO2011127069A1 (fr) 2010-04-06 2011-10-13 Targeted Growth, Inc. Micro-organismes photosynthétiques modifiés pour la production de lipides
US20110250663A1 (en) 2010-04-08 2011-10-13 Ls9, Inc. Methods and compositions related to fatty alcohol biosynthetic enzymes
GB201013041D0 (en) 2010-08-03 2010-09-15 Royal Holloway & New Bedford College Carotenoids
CN103140145B (zh) 2010-08-13 2014-08-20 高级生物营养公司 用于生物材料的干的贮存稳定用组合物
WO2012033870A1 (fr) 2010-09-08 2012-03-15 The Penn State Research Foundation Phycobiliprotéines recombinantes présentant une fluorescence et des propriétés photochimiques accrues, et leurs méthodes de production et d'utilisation
WO2012055030A1 (fr) 2010-10-25 2012-05-03 National Research Council Of Canada Anticorps spécifiques de clostridium difficile et leurs applications
US20120115208A1 (en) 2010-10-26 2012-05-10 The Governors Of The University Of Alberta Modular method for rapid assembly of dna
US9523096B2 (en) 2010-12-20 2016-12-20 Matrix Genetics, Llc Modified photosynthetic microorganisms for producing lipids
EP2655605A1 (fr) 2010-12-20 2013-10-30 Matrix Genetics, LLC Microorganismes photosynthétiques modifiés pour la production de lipides
US9040264B2 (en) 2011-03-31 2015-05-26 Exxonmobil Research And Engineering Company Recombinant cyanobacterium expressing a transcription factor domain protein
EP2753701B1 (fr) 2011-09-27 2018-05-02 ExxonMobil Research and Engineering Company Acyl-acp synthase d'ester cireux
WO2013116517A2 (fr) 2012-02-03 2013-08-08 Matrix Genetics, Llc Micro-organismes photosynthétiques modifiés pour la production continue de composés contenant du carbone
US8962299B2 (en) 2012-02-29 2015-02-24 Exxonmobil Research And Engineering Company Four-gene pathway for wax ester synthesis
JP2015509533A (ja) 2012-03-09 2015-03-30 マトリックス ジェネティクス, エルエルシー 修飾されたジアシルグリセロールアシルトランスフェラーゼタンパク質およびその使用方法
CN103382482A (zh) * 2012-05-03 2013-11-06 南开大学 一种食用安全性整合型螺旋藻高效表达载体及其应用技术
JP6306583B2 (ja) 2012-07-18 2018-04-04 イェダ リサーチ アンド デベロップメント カンパニー リミテッド 代謝経路の生成物の製造方法
US9382554B2 (en) 2012-07-27 2016-07-05 Wisys Technology Foundation, Inc. Methods for isoprene and pinene production in cyanobacteria
JP2015535224A (ja) 2012-10-24 2015-12-10 ナショナル リサーチ カウンシル オブ カナダ 抗カンピロバクター・ジェジュニ(campylobacterjejuni)抗体及びその使用
WO2014164232A1 (fr) 2013-03-13 2014-10-09 Matrix Genetics, Llc Cyanobactéries qui produisent des protéines d'empaquetage des lipides
WO2014164566A2 (fr) 2013-03-13 2014-10-09 Matrix Genetics, Llc Cyanobactérie présentant une activité photsynthétique améliorée
US9873907B2 (en) 2013-05-29 2018-01-23 Agilent Technologies, Inc. Method for fragmenting genomic DNA using CAS9
CN103820459B (zh) * 2014-01-22 2016-05-25 深圳大学 一种能预防禽流感的藻类饲料与应用
AU2015315168B2 (en) * 2014-09-09 2021-07-29 Lumen Bioscience, Inc. Targeted mutagenesis in spirulina
EP3194424A1 (fr) 2014-09-15 2017-07-26 Matrix Genetics, LLC Cyanobactérie présentant une activité photsynthétique améliorée
CN104311649B (zh) 2014-09-23 2018-01-09 中国科学院植物研究所 一种能提高植物光合效率的莱茵衣藻蛋白e6及其编码基因与应用
WO2016061275A1 (fr) 2014-10-14 2016-04-21 Matrix Genetics, Llc Cyanobactéries modifiées pour la production de caroténoïdes
WO2016073562A1 (fr) 2014-11-04 2016-05-12 Synthetic Biologics, Inc. Procédés et compositions pour l'inhibition de clostridium difficile
CN104479010A (zh) * 2014-12-20 2015-04-01 朱金凤 一种破壁螺旋藻蛋白粉的制备工艺
CN104480133A (zh) * 2015-01-06 2015-04-01 厦门大学 利用转座子介导外源基因导入螺旋藻的方法
US10654901B2 (en) 2015-04-24 2020-05-19 Lumen Bioscience, Inc. Microorganisms with increased photosynthetic capacity
US10787488B2 (en) 2015-07-10 2020-09-29 Lumen Bioscience, Inc. Microorganisms with broadened light absorption capability and increased photosynthetic activity
US11466075B2 (en) 2015-10-13 2022-10-11 University Of Maryland, Baltimore Yeast-based immunotherapy against clostridium difficile infection
WO2017139687A1 (fr) 2016-02-12 2017-08-17 Matrix Genetics, Llc Micro-organismes dotés de voies d'échappement à nadph pour réduire la photodégradation et stimuler la croissance dans des conditions de forte lumière
TWI591180B (zh) 2016-02-18 2017-07-11 基酵生物科技股份有限公司 提升耐熱性的植酸酶
WO2017208857A1 (fr) 2016-05-30 2017-12-07 ユニチカ株式会社 Procédé de production de polymère et dispositif de production
US12447202B2 (en) 2018-05-17 2025-10-21 Lumen Bioscience, Inc. Arthrospira platensis oral vaccine delivery platform
WO2020018586A1 (fr) 2018-07-16 2020-01-23 Lumen Bioscience, Inc. Phycobiliprotéines thermostables produites dans la spiruline
WO2021003456A1 (fr) 2019-07-03 2021-01-07 Lumen Bioscience, Inc. Plate-forme d'administration non parentérale d'agent thérapeutique d'arthrospira platensis
CN112094342B (zh) 2020-09-25 2022-05-13 中国科学技术大学 与SARS-CoV-2 RBD结合的羊驼源纳米抗体
EP4267185A4 (fr) 2020-12-23 2024-10-30 Lumen Bioscience, Inc. Constructions comprenant des anticorps vhh à domaine unique dirigé contre le sars-cov-2
WO2022159819A1 (fr) 2021-01-22 2022-07-28 Lumen Bioscience, Inc. Expression et fabrication d'agents thérapeutiques protéiques dans la spiruline

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