MC360A1 - Procédé de préparation de nouveaux composés de la famille des tétracyclines - Google Patents

Procédé de préparation de nouveaux composés de la famille des tétracyclines

Info

Publication number
MC360A1
MC360A1 MC381A MC381A MC360A1 MC 360 A1 MC360 A1 MC 360A1 MC 381 A MC381 A MC 381A MC 381 A MC381 A MC 381A MC 360 A1 MC360 A1 MC 360A1
Authority
MC
Monaco
Prior art keywords
acid
reacted
diazonium
tetracycline
deoxytetracycline
Prior art date
Application number
MC381A
Other languages
English (en)
French (fr)
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of MC360A1 publication Critical patent/MC360A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MC381A 1961-04-14 1962-04-03 Procédé de préparation de nouveaux composés de la famille des tétracyclines MC360A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US102943A US3219671A (en) 1961-04-14 1961-04-14 Substituted 6-deoxytetracyclines and 6-demethyl-6-deoxytetracyclines

Publications (1)

Publication Number Publication Date
MC360A1 true MC360A1 (fr) 1963-01-02

Family

ID=22292528

Family Applications (1)

Application Number Title Priority Date Filing Date
MC381A MC360A1 (fr) 1961-04-14 1962-04-03 Procédé de préparation de nouveaux composés de la famille des tétracyclines

Country Status (9)

Country Link
US (1) US3219671A (de)
AT (1) AT247517B (de)
BE (1) BE615588A (de)
CH (1) CH397657A (de)
ES (1) ES275944A1 (de)
FR (1) FR1977M (de)
GB (1) GB952972A (de)
LU (1) LU41501A1 (de)
MC (1) MC360A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3455800A (en) * 1966-12-01 1969-07-15 American Cyanamid Co Process of preparing 4-dedimethyl-aminotetracyclines
US5371076A (en) * 1993-04-02 1994-12-06 American Cyanamid Company 9-[(substituted glycyl)amido]-6-(substituted)-5-hydroxy-6-deoxytetracyclines
US8106225B2 (en) * 1999-09-14 2012-01-31 Trustees Of Tufts College Methods of preparing substituted tetracyclines with transition metal-based chemistries
CZ301835B6 (cs) * 1999-09-14 2010-07-07 Trustees Of Tufts College Zpusob prípravy 7-, 9- nebo 13- substituované tetracyklinové slouceniny, reaktivní tetracyklinový chemický komplex a tetracyklinová sloucenina substituovaná v poloze 7 nebo 9
WO2001098236A2 (en) 2000-06-16 2001-12-27 Trustees Of Tufts College 7-phenyl-substituted tetracycline compounds
US20020132798A1 (en) * 2000-06-16 2002-09-19 Nelson Mark L. 7-phenyl-substituted tetracycline compounds
BR0112265A (pt) 2000-07-07 2003-06-24 Tufts College Compostos de tetraciclina substituìda, e de sanciclina 7-substituìda, método para tratar um estado responsivo à tetraciclina em um indivìduo, e, composição farmacêutica
CZ2003344A3 (cs) 2000-07-07 2003-05-14 Trustees Of Tufts College 9-Substituované minocyklinové sloučeniny
EP1503981A4 (de) 2002-03-21 2007-08-15 Paratek Pharm Innc Substituierte tetracyclinverbindungen
WO2005009943A2 (en) 2003-07-09 2005-02-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
KR101171408B1 (ko) 2004-05-21 2012-08-08 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 테트라사이클린 및 이의 유사체의 합성
AU2006210406C1 (en) 2005-02-04 2013-03-07 Paratek Pharmaceuticals, Inc. 11a, 12-derivatives of tetracycline compounds
JP5335664B2 (ja) * 2006-04-07 2013-11-06 プレジデント アンド フェロウズ オブ ハーバード カレッジ テトラサイクリンおよびその類似体の合成
EP2479169B1 (de) 2006-10-11 2014-12-03 President and Fellows of Harvard College Synthese eines Enon-Zwischenprodukts
WO2010126607A2 (en) 2009-04-30 2010-11-04 President And Fellows Of Harvard College Synthesis of tetracyclines and intermediates thereto

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2812349A (en) * 1954-03-11 1957-11-05 Pfizer & Co C Alkanoic acid esters of tetracycline antibiotics
NL247838A (de) * 1959-01-30
US2976318A (en) * 1959-05-18 1961-03-21 Pfizer & Co C Tetracycline derivatives and process of producing the same

Also Published As

Publication number Publication date
US3219671A (en) 1965-11-23
CH397657A (de) 1965-08-31
AT247517B (de) 1966-06-10
ES275944A1 (es) 1962-07-16
GB952972A (en) 1964-03-18
LU41501A1 (de) 1962-06-06
BE615588A (fr) 1962-09-26
FR1977M (fr) 1963-08-19

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