MD940152A - Compoziţie farmaceutică pentru tratarea infecţiilor şi bolilor, provocate de virusul hepatitei V (HBV) - Google Patents

Compoziţie farmaceutică pentru tratarea infecţiilor şi bolilor, provocate de virusul hepatitei V (HBV)

Info

Publication number
MD940152A
MD940152A MD94-0152A MD940152A MD940152A MD 940152 A MD940152 A MD 940152A MD 940152 A MD940152 A MD 940152A MD 940152 A MD940152 A MD 940152A
Authority
MD
Moldova
Prior art keywords
hbv
hepatitis
infections
virus
treatment
Prior art date
Application number
MD94-0152A
Other languages
English (en)
Russian (ru)
Inventor
W.Adair Dennis
A.Smiles Kenneth
King Dannie
Original Assignee
Oclassen Pharmaceutical, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oclassen Pharmaceutical, Inc. filed Critical Oclassen Pharmaceutical, Inc.
Publication of MD940152A publication Critical patent/MD940152A/ro

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Prezenta invenţie se referă la compoziţia farmaceutică, destinată pentru tratarea pacienţilor afectaţi de infecţii sau boli, provocate de virusul hepatitei.Compoziţia conţine: compusul 1-2-dezoxi-2-fluoro-b-D-arabinofuranozil-5-iodouracil (FIAV) în cantitate suficientă pentru asigurarea dozei FIAV antivirotice reduse, dar efective, precum şi un purtător farmaceutic acceptabil. Preparatul contribuie la reducerea bruscă şi efectivă a nivelului marcherilor circulanţi, asociaţi cu HBV. Prezenta invenţie se referă şi la procedeele de obţinere a compoziţiilor farmaceutice antivirotice.
MD94-0152A 1992-04-06 1994-06-17 Compoziţie farmaceutică pentru tratarea infecţiilor şi bolilor, provocate de virusul hepatitei V (HBV) MD940152A (ro)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US86389092A 1992-04-06 1992-04-06
US95292792A 1992-09-25 1992-09-25
US07/959,004 US5432165A (en) 1992-04-06 1992-10-09 Methods for the treatment of infection caused by Hepatitis B virus (HBV)

Publications (1)

Publication Number Publication Date
MD940152A true MD940152A (ro) 1995-12-31

Family

ID=27420427

Family Applications (1)

Application Number Title Priority Date Filing Date
MD94-0152A MD940152A (ro) 1992-04-06 1994-06-17 Compoziţie farmaceutică pentru tratarea infecţiilor şi bolilor, provocate de virusul hepatitei V (HBV)

Country Status (26)

Country Link
US (1) US5432165A (ro)
EP (1) EP0565412A1 (ro)
JP (1) JPH069403A (ro)
CN (1) CN1081879A (ro)
AP (1) AP372A (ro)
AU (1) AU662804B2 (ro)
BE (1) BE1009181A5 (ro)
BR (1) BR9306207A (ro)
CA (1) CA2092356A1 (ro)
EE (1) EE9400068A (ro)
ES (1) ES2105923B1 (ro)
FR (1) FR2689398B1 (ro)
GR (1) GR930100111A (ro)
IL (1) IL105169A0 (ro)
IT (1) IT1264332B1 (ro)
LV (1) LV10191B (ro)
MD (1) MD940152A (ro)
MX (1) MX9301922A (ro)
NO (1) NO931246L (ro)
NZ (1) NZ247188A (ro)
OA (1) OA10102A (ro)
PH (1) PH31116A (ro)
PT (1) PT101238A (ro)
SI (1) SI9300144A (ro)
WO (1) WO1993019762A1 (ro)
YU (1) YU23993A (ro)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5827727A (en) * 1990-02-01 1998-10-27 Emory University Method of resolution of 1,3-oxathiolane nucleoside enantiomers
US5444063A (en) * 1990-12-05 1995-08-22 Emory University Enantiomerically pure β-D-dioxolane nucleosides with selective anti-Hepatitis B virus activity
US6200952B1 (en) * 1993-06-02 2001-03-13 Sciclone Pharmaceuticals, Inc. Combination therapy method for treating chronic hepatitis B
US5587362A (en) * 1994-01-28 1996-12-24 Univ. Of Ga Research Foundation L-nucleosides
WO1996010649A1 (en) * 1994-09-30 1996-04-11 Southwest Foundation For Biomedical Research Isolated human hepatitis b virus polymerase and uses thereof
US6391859B1 (en) 1995-01-27 2002-05-21 Emory University [5-Carboxamido or 5-fluoro]-[2′,3′-unsaturated or 3′-modified]-pyrimidine nucleosides
US5703058A (en) 1995-01-27 1997-12-30 Emory University Compositions containing 5-fluoro-2',3'-didehydro-2',3'-dideoxycytidine or a mono-, di-, or triphosphate thereof and a second antiviral agent
US5808040A (en) * 1995-01-30 1998-09-15 Yale University L-nucleosides incorporated into polymeric structure for stabilization of oligonucleotides
US6296882B1 (en) * 2000-06-12 2001-10-02 Manuel Viamonte, Jr. Non-toxic mucosal disinfectant containing isopropyl alcohol, sesame oil, and lemon oil
US8076303B2 (en) 2005-12-13 2011-12-13 Spring Bank Pharmaceuticals, Inc. Nucleotide and oligonucleotide prodrugs
EP2427213B1 (en) * 2009-05-08 2015-04-01 Sciclone Pharmaceuticals, Inc. Alpha thymosin peptides as vaccine enhancers

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE147774C (ro) *
US4211773A (en) * 1978-10-02 1980-07-08 Sloan Kettering Institute For Cancer Research 5-Substituted 1-(2'-Deoxy-2'-substituted-β-D-arabinofuranosyl)pyrimidine nucleosides
US4594339A (en) * 1982-04-06 1986-06-10 Sloan-Kettering Institute For Cancer Research Anti-herpes virus compositions containing 5-substituted 1-2'(deoxy-2-'-substituted-β-d-arabinofuranosyl)pyrimedene nucleosides
US4666892A (en) * 1984-03-06 1987-05-19 Sloan-Kettering Memorial Cancer Center Method and composition for hepatitis treatment with pyrimidine nucleoside compounds

Also Published As

Publication number Publication date
LV10191A (lv) 1994-10-20
EP0565412A1 (en) 1993-10-13
IT1264332B1 (it) 1996-09-23
MX9301922A (es) 1993-10-01
NO931246L (no) 1993-10-07
AU3530293A (en) 1993-10-07
FR2689398B1 (fr) 1994-11-18
OA10102A (en) 1996-12-18
CN1081879A (zh) 1994-02-16
EE9400068A (et) 1995-12-15
SI9300144A (en) 1994-03-31
WO1993019762A1 (en) 1993-10-14
FR2689398A1 (fr) 1993-10-08
BE1009181A5 (fr) 1996-12-03
YU23993A (sh) 1997-05-28
AP9300513A0 (en) 1993-04-30
AU662804B2 (en) 1995-09-14
PT101238A (pt) 1994-03-31
CA2092356A1 (en) 1993-10-07
AP372A (en) 1994-11-24
ES2105923A1 (es) 1997-10-16
ITTO930226A0 (it) 1993-04-05
NO931246D0 (no) 1993-03-31
LV10191B (en) 1995-04-20
GR930100111A (el) 1993-12-30
ITTO930226A1 (it) 1994-10-05
PH31116A (en) 1998-02-28
ES2105923B1 (es) 1998-07-01
IL105169A0 (en) 1993-07-08
US5432165A (en) 1995-07-11
JPH069403A (ja) 1994-01-18
NZ247188A (en) 1995-05-26
BR9306207A (pt) 1998-06-23

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Legal Events

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