MEP33108A - Bengamide derivatives, method for the production thereof and use thereof for the treatment of cancer - Google Patents

Bengamide derivatives, method for the production thereof and use thereof for the treatment of cancer

Info

Publication number
MEP33108A
MEP33108A MEP-331/08A MEP33108A MEP33108A ME P33108 A MEP33108 A ME P33108A ME P33108 A MEP33108 A ME P33108A ME P33108 A MEP33108 A ME P33108A
Authority
ME
Montenegro
Prior art keywords
cancer
treatment
production
bengamide derivatives
bengamide
Prior art date
Application number
MEP-331/08A
Other languages
Bosnian (bs)
English (en)
Inventor
Holger Hoffmann
Sabine Haag-Richter
Michael Kurz
Heiko Tietgen
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of MEP33108A publication Critical patent/MEP33108A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/08—Oxygen atoms
    • C07D223/10—Oxygen atoms attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/12—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
MEP-331/08A 2003-10-24 2004-10-08 Bengamide derivatives, method for the production thereof and use thereof for the treatment of cancer MEP33108A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10349669A DE10349669B3 (de) 2003-10-24 2003-10-24 Bengamide-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung
PCT/EP2004/011244 WO2005044803A1 (fr) 2003-10-24 2004-10-08 Derives de bengamide, procede de preparation desdits derives et leur utilisation pour traiter les maladies cancereuses

Publications (1)

Publication Number Publication Date
MEP33108A true MEP33108A (en) 2010-10-10

Family

ID=34484998

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-331/08A MEP33108A (en) 2003-10-24 2004-10-08 Bengamide derivatives, method for the production thereof and use thereof for the treatment of cancer

Country Status (29)

Country Link
EP (2) EP1680405B1 (fr)
JP (1) JP4769190B2 (fr)
KR (1) KR20060120044A (fr)
CN (2) CN101294173A (fr)
AR (1) AR046553A1 (fr)
AT (2) ATE420074T1 (fr)
AU (1) AU2004287561B2 (fr)
BR (1) BRPI0415529A (fr)
CA (1) CA2543003A1 (fr)
CL (1) CL2009000674A1 (fr)
CY (1) CY1110458T1 (fr)
DE (3) DE10349669B3 (fr)
DK (1) DK1680405T3 (fr)
ES (1) ES2320894T3 (fr)
HR (1) HRP20090187T1 (fr)
IL (1) IL174524A (fr)
MA (1) MA28213A1 (fr)
ME (1) MEP33108A (fr)
MX (1) MXPA06004084A (fr)
NO (1) NO20062149L (fr)
NZ (1) NZ546744A (fr)
PL (1) PL1680405T3 (fr)
PT (1) PT1680405E (fr)
RS (1) RS20060263A (fr)
RU (1) RU2357956C2 (fr)
SI (1) SI1680405T1 (fr)
UY (1) UY28574A1 (fr)
WO (1) WO2005044803A1 (fr)
ZA (1) ZA200602231B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2878528B1 (fr) 2004-11-29 2008-05-16 Aventis Pharma Sa 2-alcoxy-3,4,5-trihydroxy-alkylamides, leur preparation, compositions les contenant et utilisation
FR2878525B1 (fr) 2004-11-29 2007-02-23 Aventis Pharma Sa Bengamides possedant un cycle caprolactame substitue, procede de preparation, compositions les contenant et utilisation
FR2901556A1 (fr) 2006-05-24 2007-11-30 Sanofi Aventis Sa Derives de 2-alcoxy-3,4,5-trihydroxy-alkylamide, leur preparation, compositions les contenant et utilisation
FR2901555A1 (fr) 2006-05-24 2007-11-30 Sanofi Aventis Sa 2-alcoxy-3,4,5-trihydroxy-alkylamide-benzothiazepine, leur preparation, compositions les contenant et utilisation
FR2901554B1 (fr) 2006-05-24 2011-04-01 Sanofi Aventis 2-alcoxy-3,4,5-trihydroxy-alkylamide-benzazepine, leur preparation, compositions les contenant et utilisation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2061490T3 (es) * 1986-04-04 1994-12-16 Sankyo Co Derivados de perhidrotiazepina y perhidroazepina, su preparacion y uso en terapeutica.
CO5140099A1 (es) * 1998-11-17 2002-03-22 Novartis Ag Ciertas caprolactamas sustituidas, composiciones farmaceuticas que las contienen, y su uso en el tratamiento de tumores
CN1191237C (zh) * 2000-05-11 2005-03-02 诺瓦提斯公司 取代的己内酰胺碳酸酯与醚和它们作为抗肿瘤剂的用途
JP2004262793A (ja) * 2003-02-28 2004-09-24 Noyaku Bio Technology Kaihatsu Gijutsu Kenkyu Kumiai 化合物ｎ−９０１１、その製造法及び用途
BRPI0412843A (pt) * 2003-07-25 2006-09-26 Novartis Ag lactamas substituìdas e uso das mesmas como agentes anticáncer

Also Published As

Publication number Publication date
DE502004008837D1 (de) 2009-02-26
IL174524A (en) 2012-08-30
AU2004287561B2 (en) 2011-06-02
PT1680405E (pt) 2009-03-31
HRP20090187T1 (en) 2009-05-31
JP4769190B2 (ja) 2011-09-07
CY1110458T1 (el) 2015-04-29
MXPA06004084A (es) 2006-06-27
BRPI0415529A (pt) 2006-12-26
RS20060263A (sr) 2008-09-29
AR046553A1 (es) 2005-12-14
JP2007509084A (ja) 2007-04-12
MA28213A1 (fr) 2006-10-02
ES2320894T3 (es) 2009-05-29
DE10349669B3 (de) 2005-05-25
NZ546744A (en) 2009-03-31
ATE477244T1 (de) 2010-08-15
UY28574A1 (es) 2005-05-31
EP1873146A2 (fr) 2008-01-02
EP1873146B1 (fr) 2010-08-11
EP1680405A1 (fr) 2006-07-19
CA2543003A1 (fr) 2005-05-19
CN100398520C (zh) 2008-07-02
RU2006117769A (ru) 2007-11-27
IL174524A0 (en) 2006-08-01
EP1680405B1 (fr) 2009-01-07
DK1680405T3 (da) 2009-05-04
CL2009000674A1 (es) 2009-08-07
SI1680405T1 (sl) 2009-06-30
KR20060120044A (ko) 2006-11-24
PL1680405T3 (pl) 2009-06-30
AU2004287561A1 (en) 2005-05-19
ATE420074T1 (de) 2009-01-15
ZA200602231B (en) 2007-06-27
DE502004011536D1 (de) 2010-09-23
WO2005044803A1 (fr) 2005-05-19
CN1871217A (zh) 2006-11-29
EP1873146A3 (fr) 2008-05-21
NO20062149L (no) 2006-07-11
HK1098131A1 (zh) 2007-07-13
RU2357956C2 (ru) 2009-06-10
CN101294173A (zh) 2008-10-29

Similar Documents

Publication Publication Date Title
MXPA04000622A (es) Pirazolilcarboxanilidas como funguicidas.
TW200500339A (en) Pyrrolidine derivatives, and process for the preparation
TNSN05194A1 (en) Substituted n-arylheterocycles, method for production and use thereof as medicaments
TWI232219B (en) Compounds containing cyclohexane group, process for preparing them and pharmaceutical composition containing them
MXPA05012362A (es) Yodopirazolilcarboxanilidas.
BR0307432A (pt) Difluormetiltiazolilcarboxanilidas
AU2003202585A1 (en) Disubstituted thiazolyl carboxanilides and their use as microbicides
TW200510325A (en) 2-acylamino-4-phenylthiazole derivatives, preparation thereof and therapeutic application thereof
MY136430A (en) N-adamantylmethyl derivatives, pharmaceutical compositions containing them and processes for their preparation
MXPA04006184A (es) Compuestos derivados de 1h-pirazolilo, para el uso en enfermedades asociadas con el receptor 5-ht2c.
TW200630374A (en) Thiazolyldihydroindazoles
IL183636A0 (en) Quinoline derivative, use and production thereof, and drug containing the same
IL176111A0 (en) 2-(1h-indolylsulfanyl)-benzyl amine derivatives as ssri
IL175819A0 (en) Tricyclic indole hydroxyethylamine derivatives and their use in the treatment of alzheimer's disease
MXPA06004308A (es) Isopentilcarboxanilidas para la lucha contra los microorganismos indeseables.
MXPA05004273A (es) Derivados de fenilalquil y piridilalquil piperazina.
MEP33108A (en) Bengamide derivatives, method for the production thereof and use thereof for the treatment of cancer
IL166057A0 (en) Urea-substituted and urethane-substituted acylureas methods for the production thereof and their useas medicaments
MY149864A (en) Flavouring-containing pharmaceutical formulations with improved pharmaceutical properties
PL367429A1 (en) Protected 3,5-dihydroxy-2,2-dimethyl-valeronitriles for the synthesis of epothilones and derivatives and method for the production and use thereof
NZ515108A (en) Novel ribose-substituted aromatic amides, method for the production and use thereof as medicaments
MXPA05008525A (es) Oxatiincarboxamidas.
EA200600777A1 (ru) N-замещённые пиразолилкарбоксанилиды
TW200504051A (en) Novel acridine derivatives and their use as medicaments
GEP20032929B (en) 6-O-Methyl-Erythromycin A Class, Novel 8a-and 9a-15-Membered Lactams, Method for Their Production and Pharmaceutical Composition for Treatment of Bacterial Infections