MX2012015252A - Estimuladores de sgc. - Google Patents

Estimuladores de sgc.

Info

Publication number
MX2012015252A
MX2012015252A MX2012015252A MX2012015252A MX2012015252A MX 2012015252 A MX2012015252 A MX 2012015252A MX 2012015252 A MX2012015252 A MX 2012015252A MX 2012015252 A MX2012015252 A MX 2012015252A MX 2012015252 A MX2012015252 A MX 2012015252A
Authority
MX
Mexico
Prior art keywords
sgc stimulators
stimulators
compounds
useful
sgc
Prior art date
Application number
MX2012015252A
Other languages
English (en)
Inventor
Ara Mermerian
Charles Kim
Joel Moore
Jason Rohde
Takashi Nakai
Thomas Wai-Ho Lee
Nicholas Robert Perl
Rajesh R Iyengar
Original Assignee
Ironwood Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ironwood Pharmaceuticals Inc filed Critical Ironwood Pharmaceuticals Inc
Publication of MX2012015252A publication Critical patent/MX2012015252A/es

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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

Se describen compuestos de Fórmula I. Los mismos son útiles como estimuladores de sGC, en particular estimuladores independientes de NO y dependientes de hemo. Estos compuestos pueden ser útiles para tratar, prevenir o manejar distintos trastornos que se divulgan en la presente. (Ver Formula).
MX2012015252A 2010-06-30 2011-06-30 Estimuladores de sgc. MX2012015252A (es)

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US20190345130A1 (en) 2019-11-14
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