MX2017002085A - Tratamientos con nanopartículas núcleo-corteza de proteína/oligonucleótido. - Google Patents

Tratamientos con nanopartículas núcleo-corteza de proteína/oligonucleótido.

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Publication number
MX2017002085A
MX2017002085A MX2017002085A MX2017002085A MX2017002085A MX 2017002085 A MX2017002085 A MX 2017002085A MX 2017002085 A MX2017002085 A MX 2017002085A MX 2017002085 A MX2017002085 A MX 2017002085A MX 2017002085 A MX2017002085 A MX 2017002085A
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Mexico
Prior art keywords
protein
shell nanoparticle
core
nanoparticle therapeutics
oligonucleotide core
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Application number
MX2017002085A
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English (en)
Inventor
A Mirkin Chad
D Brodin Jeffrey
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Univ Northwestern
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Application filed by Univ Northwestern filed Critical Univ Northwestern
Publication of MX2017002085A publication Critical patent/MX2017002085A/es

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    • A61K38/44—Oxidoreductases (1)
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2468—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1) acting on beta-galactose-glycoside bonds, e.g. carrageenases (3.2.1.83; 3.2.1.157); beta-agarase (3.2.1.81)
    • C12N9/2471—Beta-galactosidase (3.2.1.23), i.e. exo-(1-->4)-beta-D-galactanase
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    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01023—Beta-galactosidase (3.2.1.23), i.e. exo-(1-->4)-beta-D-galactanase
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Abstract

La presente descripción se refiere a nanopartículas núcleo-corteza, composiciones que comprenden nanopartículas núcleo-corteza, y métodos para su uso.
MX2017002085A 2014-08-19 2015-08-19 Tratamientos con nanopartículas núcleo-corteza de proteína/oligonucleótido. MX2017002085A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201462039340P 2014-08-19 2014-08-19
US201462039608P 2014-08-20 2014-08-20
US201562137183P 2015-03-23 2015-03-23
PCT/US2015/045971 WO2016028940A1 (en) 2014-08-19 2015-08-19 Protein/oligonucleotide core-shell nanoparticle therapeutics

Publications (1)

Publication Number Publication Date
MX2017002085A true MX2017002085A (es) 2017-08-21

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017002085A MX2017002085A (es) 2014-08-19 2015-08-19 Tratamientos con nanopartículas núcleo-corteza de proteína/oligonucleótido.

Country Status (8)

Country Link
US (1) US12264344B2 (es)
EP (1) EP3183007B1 (es)
JP (1) JP6797108B2 (es)
CN (2) CN106794256B (es)
AU (3) AU2015305482B2 (es)
CA (1) CA2958431A1 (es)
MX (1) MX2017002085A (es)
WO (1) WO2016028940A1 (es)

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WO2018039629A2 (en) 2016-08-25 2018-03-01 Northwestern University Micellar spherical nucleic acids from thermoresponsive, traceless templates
CN108148758B (zh) * 2016-12-05 2021-09-17 中国科学院大连化学物理研究所 一种绒毛外滋养细胞纳米颗粒暴露的体外模型建立方法
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US20210402000A1 (en) * 2018-10-10 2021-12-30 University Of Washington High-polymer-density bioconjugate compositions and related methods
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