MX2020004939A - Fabricacion de composiciones de celulas islote y metodos de uso de las mismas. - Google Patents

Fabricacion de composiciones de celulas islote y metodos de uso de las mismas.

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Publication number
MX2020004939A
MX2020004939A MX2020004939A MX2020004939A MX2020004939A MX 2020004939 A MX2020004939 A MX 2020004939A MX 2020004939 A MX2020004939 A MX 2020004939A MX 2020004939 A MX2020004939 A MX 2020004939A MX 2020004939 A MX2020004939 A MX 2020004939A
Authority
MX
Mexico
Prior art keywords
methods
islet cell
cell manufacturing
manufacturing compositions
compositions
Prior art date
Application number
MX2020004939A
Other languages
English (en)
Inventor
Felicia J Pagliuca
Austin Thiel
Jihad Yasin
Evrett Thompson
Original Assignee
Semma Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Semma Therapeutics Inc filed Critical Semma Therapeutics Inc
Publication of MX2020004939A publication Critical patent/MX2020004939A/es

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • C12N5/0678—Stem cells; Progenitor cells; Precursor cells
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A61K35/39—Pancreas; Islets of Langerhans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
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    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
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Abstract

En el presente documento se describen composiciones y métodos útiles para fabricar células SC-ß, y poblaciones aisladas de células SC-ß para su uso en diversas aplicaciones, tales como terapia celular.
MX2020004939A 2017-11-15 2018-11-15 Fabricacion de composiciones de celulas islote y metodos de uso de las mismas. MX2020004939A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762586808P 2017-11-15 2017-11-15
US201862669170P 2018-05-09 2018-05-09
PCT/US2018/061364 WO2019099725A1 (en) 2017-11-15 2018-11-15 Islet cell manufacturing compositions and methods of use

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MX2020004939A true MX2020004939A (es) 2020-11-11

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US (3) US11945795B2 (es)
EP (1) EP3710021A4 (es)
JP (2) JP7428653B2 (es)
KR (2) KR102789149B1 (es)
CN (2) CN118497104A (es)
AU (2) AU2018370029B2 (es)
BR (1) BR112020009275A2 (es)
CA (1) CA3081762A1 (es)
IL (3) IL312134B2 (es)
MX (1) MX2020004939A (es)
WO (1) WO2019099725A1 (es)

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Publication number Priority date Publication date Assignee Title
IL313825B2 (en) 2017-06-14 2025-07-01 Vertex Pharma Devices and methods for administering medications
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EP3710021A1 (en) 2020-09-23
EP3710021A4 (en) 2021-08-11
WO2019099725A1 (en) 2019-05-23
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