MX2020008537A - Sales, formas cristalinas y metodos de produccion de las mismas. - Google Patents

Sales, formas cristalinas y metodos de produccion de las mismas.

Info

Publication number
MX2020008537A
MX2020008537A MX2020008537A MX2020008537A MX2020008537A MX 2020008537 A MX2020008537 A MX 2020008537A MX 2020008537 A MX2020008537 A MX 2020008537A MX 2020008537 A MX2020008537 A MX 2020008537A MX 2020008537 A MX2020008537 A MX 2020008537A
Authority
MX
Mexico
Prior art keywords
methods
salts
crystalline forms
production
methylmethanamine
Prior art date
Application number
MX2020008537A
Other languages
English (en)
Inventor
Shahla Jamzad
Haitao Zhang
Andrea Bauer
Nandkumar Nivritti Bhogle
Xiaoxia Chen
Robert Joseph Prytko
Kostas Saranteas
Harold Scott Wilkinson
Michael Joseph Sizensky
Original Assignee
Sunovion Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sunovion Pharmaceuticals Inc filed Critical Sunovion Pharmaceuticals Inc
Publication of MX2020008537A publication Critical patent/MX2020008537A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Se proporcionan sales de (S)-(4,5-dihidro-7H-tieno[ 2,3-c]piran-7-i1)-N-metilmetanamina y varias de sus formas cristalinas, y composiciones, medicamentos, formulaciones farmacéuticamente aceptables de las mismas, y métodos para hacerlas. Además, se proporcionan compuestos que comprenden distribuciones de tamaño de partícula específicas de (S)-(4,5-dihidro-7H-tieno[2,3-c]piran-7-il)-N-metilmetanamina HC1 cristalino y métodos de elaboración y modulación de las distribuciones del tamaño de partícula.
MX2020008537A 2018-02-16 2019-02-15 Sales, formas cristalinas y metodos de produccion de las mismas. MX2020008537A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862710416P 2018-02-16 2018-02-16
PCT/US2019/018265 WO2019161238A1 (en) 2018-02-16 2019-02-15 Salts, crystal forms, and production methods thereof

Publications (1)

Publication Number Publication Date
MX2020008537A true MX2020008537A (es) 2021-01-08

Family

ID=65529921

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2020008537A MX2020008537A (es) 2018-02-16 2019-02-15 Sales, formas cristalinas y metodos de produccion de las mismas.
MX2022016230A MX2022016230A (es) 2018-02-16 2020-08-14 Clorhidrato de (s)-(4,5-dihidro-7h-tieno[2,3-c]piran-7-il)-nmetilm etanamina cristalino y formulaciones de las mismas.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2022016230A MX2022016230A (es) 2018-02-16 2020-08-14 Clorhidrato de (s)-(4,5-dihidro-7h-tieno[2,3-c]piran-7-il)-nmetilm etanamina cristalino y formulaciones de las mismas.

Country Status (15)

Country Link
US (5) US10815249B2 (es)
EP (1) EP3752508A1 (es)
JP (3) JP7453148B2 (es)
KR (1) KR102746817B1 (es)
CN (2) CN118406063A (es)
AU (2) AU2019222491B2 (es)
CA (1) CA3091292A1 (es)
EA (1) EA202091945A1 (es)
IL (3) IL285739B2 (es)
MX (2) MX2020008537A (es)
MY (1) MY208150A (es)
PH (1) PH12020551256A1 (es)
SG (1) SG11202007823PA (es)
UA (1) UA130249C2 (es)
WO (1) WO2019161238A1 (es)

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PT3252057T (pt) 2009-12-04 2024-06-04 Sunovion Pharmaceuticals Inc Compostos multicíclicos e métodos de utilização dos mesmos
MX2019000982A (es) 2016-07-29 2019-07-04 Sunovion Pharmaceuticals Inc Compuestos y composiciones y usos de los mismos.
CN116808023A (zh) 2017-02-16 2023-09-29 桑诺维恩药品公司 治疗精神分裂症的方法
JP7191085B2 (ja) 2017-08-02 2022-12-16 サノビオン ファーマシューティカルズ インク イソクロマン化合物およびその使用
MX2020008537A (es) 2018-02-16 2021-01-08 Sunovion Pharmaceuticals Inc Sales, formas cristalinas y metodos de produccion de las mismas.
CA3122261A1 (en) 2018-12-06 2020-06-11 Sunovion Pharmaceuticals Inc. Methods of treating neurological and psychiatric disorders
CA3180115A1 (en) * 2020-04-14 2021-10-21 Sunovion Pharmaceuticals Inc. (s)-(4,5-dihydro-7h-thieno[2,3-c]pyran-7-yl)-n-methylmethanamine for treating neurological and psychiatric disorders
EP4214212A1 (en) 2020-09-16 2023-07-26 Teva Pharmaceuticals International GmbH Solid state forms of sep-363856 and process for preparation thereof
US20230241024A1 (en) * 2021-09-23 2023-08-03 Sunovion Pharmaceuticals Inc. Methods of treating metabolic disorders
AU2023334027A1 (en) 2022-08-30 2025-01-09 Sumitomo Pharma America, Inc. Ulotaront for the adjuvant treatment of major depressive disorder
EP4601634A1 (en) 2022-10-13 2025-08-20 Sumitomo Pharma America, Inc. Methods of reducing physical dependence to neuropsychiatric treatments
AU2023367071A1 (en) 2022-10-28 2025-06-12 Sumitomo Pharma America, Inc. Ulotaront for treating anxiety and associated conditions
JP2025538225A (ja) 2022-11-15 2025-11-26 スミトモ・ファーマ・アメリカ・インコーポレイテッド 神経精神病薬を切り替える方法
US20250262185A1 (en) 2024-02-16 2025-08-21 Sumitomo Pharma America, Inc. Methods of administering neuropsychiatric medications based on renal impairment
TW202600129A (zh) 2024-02-23 2026-01-01 美商住友製藥美國公司 烏洛托隆（ulotaront）鹽酸鹽的製造方法

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