MX2020009670A - Metodos de cultivo por perfusion y usos de los mismos. - Google Patents
Metodos de cultivo por perfusion y usos de los mismos.Info
- Publication number
- MX2020009670A MX2020009670A MX2020009670A MX2020009670A MX2020009670A MX 2020009670 A MX2020009670 A MX 2020009670A MX 2020009670 A MX2020009670 A MX 2020009670A MX 2020009670 A MX2020009670 A MX 2020009670A MX 2020009670 A MX2020009670 A MX 2020009670A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- culturing methods
- perfusion culturing
- culturing
- perfusion
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 5
- 238000012258 culturing Methods 0.000 title abstract 4
- 230000010412 perfusion Effects 0.000 title abstract 2
- 238000004113 cell culture Methods 0.000 abstract 1
- 210000004962 mammalian cell Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M1/00—Apparatus for enzymology or microbiology
- C12M1/26—Inoculator or sampler
- C12M1/32—Inoculator or sampler multiple field or continuous type
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
- C12Q1/045—Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/12—Well or multiwell plates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/10—Rotating vessel
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/10—Perfusion
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2527/00—Culture process characterised by the use of mechanical forces, e.g. strain, vibration
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Sustainable Development (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
En la presente descripción se proporcionan métodos para cultivar una célula de mamífero y varios métodos que utilizan estos métodos de cultivo. Asimismo, se proporcionan placas de cultivo celular de múltiples pocillos, por ejemplo, para uso en métodos de cultivo por perfusión.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462009058P | 2014-06-06 | 2014-06-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2020009670A true MX2020009670A (es) | 2020-10-08 |
Family
ID=53484156
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2016016142A MX2016016142A (es) | 2014-06-06 | 2015-06-05 | Metodos de cultivo por perfusion y usos de los mismos. |
| MX2020009670A MX2020009670A (es) | 2014-06-06 | 2016-12-06 | Metodos de cultivo por perfusion y usos de los mismos. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2016016142A MX2016016142A (es) | 2014-06-06 | 2015-06-05 | Metodos de cultivo por perfusion y usos de los mismos. |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US11060058B2 (es) |
| EP (1) | EP3152293B1 (es) |
| JP (3) | JP6915992B2 (es) |
| KR (2) | KR102479281B1 (es) |
| CN (1) | CN106795495A (es) |
| AU (2) | AU2015269184B2 (es) |
| BR (1) | BR112016028512A8 (es) |
| CA (1) | CA2951255A1 (es) |
| ES (1) | ES3040723T3 (es) |
| IL (1) | IL249384A0 (es) |
| MX (2) | MX2016016142A (es) |
| RU (3) | RU2708919C2 (es) |
| SG (2) | SG11201610167WA (es) |
| TW (2) | TW202204596A (es) |
| WO (1) | WO2015188106A2 (es) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014130872A2 (en) | 2013-02-22 | 2014-08-28 | Genzyme Corporation | Microcarrier perfusion culturing methods and uses thereof |
| ES2717927T3 (es) | 2013-02-22 | 2019-06-26 | Genzyme Corp | Procedimientos de cultivo por perfusión de microportadores y usos de los mismos |
| TW202204596A (zh) * | 2014-06-06 | 2022-02-01 | 美商健臻公司 | 灌注培養方法及其用途 |
| TWI707949B (zh) | 2014-06-09 | 2020-10-21 | 美商健臻公司 | 種子罐培養法(seed train processes)及其用途 |
| CA3225136A1 (en) | 2014-12-22 | 2016-06-30 | Genzyme Corporation | Methods of culturing a mammalian cell |
| US11292999B2 (en) | 2016-08-30 | 2022-04-05 | Finesse Solutions, Inc. | Bioreactor with multiple coupled vessels |
| JP7453151B2 (ja) * | 2018-11-02 | 2024-03-19 | 協和キリン株式会社 | 液体培地の調製方法 |
| US20220250063A1 (en) * | 2021-02-10 | 2022-08-11 | Koniku Inc. | Assay system, methods, and multi-well plate for gas stimulation of biological cells, proteins or materials |
| MX2023012193A (es) * | 2021-04-14 | 2023-10-25 | Genzyme Corp | Metodos de cultivo de perfusion de una celula de mamifero. |
| JP7732840B2 (ja) * | 2021-10-14 | 2025-09-02 | 株式会社三共 | 遊技機 |
| JP7732841B2 (ja) * | 2021-10-14 | 2025-09-02 | 株式会社三共 | 遊技機 |
| JP7732842B2 (ja) * | 2021-10-14 | 2025-09-02 | 株式会社三共 | 遊技機 |
| JP7732843B2 (ja) * | 2021-10-14 | 2025-09-02 | 株式会社三共 | 遊技機 |
| JP7732839B2 (ja) * | 2021-10-14 | 2025-09-02 | 株式会社三共 | 遊技機 |
| WO2024112917A1 (en) * | 2022-11-22 | 2024-05-30 | The University Of North Carolina At Chapel Hill | Laminar flow incorporated scaffold-based 3d cell cultures |
| DE102022214275A1 (de) * | 2022-12-22 | 2024-06-27 | Robert Bosch Gesellschaft mit beschränkter Haftung | Vorrichtung und Verfahren zur Kultivierung von Zellen |
| US20240263122A1 (en) * | 2023-02-08 | 2024-08-08 | National Central University | Bioreactor apparatus, ion-exchange substrate and method for regulation of ion concentration and cell culture thereof |
Family Cites Families (78)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| RU2058992C1 (ru) | 1993-07-14 | 1996-04-27 | Антипин Георгий Васильевич | Способ получения кормового белка и устройство для его осуществления |
| DE19612966B4 (de) | 1996-04-01 | 2009-12-10 | Novartis Vaccines And Diagnostics Gmbh & Co. Kg | MDCK-Zellen und Verfahren zur Vermehrung von Influenzaviren |
| RU2215748C2 (ru) | 1999-04-09 | 2003-11-10 | Сентро Де Инмунология Молекулар | Способ получения рекомбинантного эритропоэтина человека и полученный эритропоэтин, фармацевтическая композиция |
| CN100457914C (zh) | 1999-04-15 | 2009-02-04 | 荷兰克鲁塞尔公司 | 用编码腺病毒e1蛋白的序列在人体细胞中生产重组蛋白 |
| AT409379B (de) | 1999-06-02 | 2002-07-25 | Baxter Ag | Medium zur protein- und serumfreien kultivierung von zellen |
| UA74557C2 (en) | 1999-09-03 | 2006-01-16 | Applied Research Systems | A method for producing a heterologous secreted protein from chinese hamster ovaries cells grown on microcarriers |
| US6585971B1 (en) | 1999-11-12 | 2003-07-01 | Harbor-Ucla Research And Education Institute | Recombinant α-L-iduronidase, methods for producing and purifying the same and methods for treating disease caused by deficiencies thereof |
| JP4176472B2 (ja) | 2000-12-20 | 2008-11-05 | バイエル・フアーマシユーチカルズ・コーポレーシヨン | 哺乳動物細胞の種連続増殖(seed−trainexpansion)のための装置及び方法 |
| US6544788B2 (en) | 2001-02-15 | 2003-04-08 | Vijay Singh | Disposable perfusion bioreactor for cell culture |
| JP2005509406A (ja) | 2001-05-09 | 2005-04-14 | バイエル・フアーマシユーチカルズ・コーポレーシヨン | 哺乳動物細胞株のための低温保存袋アセンブリー |
| PT1451290E (pt) | 2001-08-31 | 2011-03-09 | Bayer Schering Pharma Ag | Uma unidade e um processo para levar a cabo a fermentação com elevada densidade celular |
| HUP0402158A2 (hu) | 2001-10-02 | 2005-01-28 | Novo Nordisk Health Care Ag | Rekombináns fehérjék előállítási eljárása eukarióta sejtekben |
| WO2003033935A1 (de) | 2001-10-11 | 2003-04-24 | Siemens Aktiengesellschaft | Dämpfungsvorrichtung sowie verfahren zum bedämpfen von bewegungen in einer dämpfungsvorrichtung |
| WO2003039459A2 (en) | 2001-11-05 | 2003-05-15 | Genvec, Inc. | Viral vector production methods and compositions |
| US20030091976A1 (en) | 2001-11-14 | 2003-05-15 | Ciphergen Biosystems, Inc. | Methods for monitoring polypeptide production and purification using surface enhanced laser desorption/ionization mass spectrometry |
| US6953692B2 (en) | 2001-12-18 | 2005-10-11 | Bayer Pharmaceuticals Corporation | Device and method for seed-train expansion of mammalian cells |
| US20050019914A1 (en) | 2003-07-24 | 2005-01-27 | Aventis Pharma Deutschland Gmbh | Perfusion process for producing erythropoietin |
| AR046510A1 (es) | 2003-07-25 | 2005-12-14 | Regeneron Pharma | Composicion de un antagonista de vegf y un agente anti-proliferativo |
| EP1508576A1 (en) | 2003-08-20 | 2005-02-23 | Crucell Holland B.V. | Efficient production of IgA in recombinant mammalian cells |
| US20050186669A1 (en) | 2004-02-20 | 2005-08-25 | Cesco Bioengineering Co., Ltd. | Apparatus and method for preparing and culturing cells |
| DK1773978T3 (da) * | 2004-05-19 | 2014-05-26 | Univ Pittsburgh | Perfunderede, tredimensionelle celle/vævssygdomsmodeller |
| TWI384069B (zh) | 2004-08-27 | 2013-02-01 | Pfizer Ireland Pharmaceuticals | 多胜肽之製法 |
| US7767446B2 (en) * | 2004-09-16 | 2010-08-03 | Becton, Dickinson And Company | Perfusion bioreactors for culturing cells |
| JP4914835B2 (ja) * | 2004-09-16 | 2012-04-11 | ベクトン・ディキンソン・アンド・カンパニー | 細胞培養用の潅流バイオリアクタ |
| DK1807101T3 (en) | 2004-09-30 | 2016-05-23 | Bayer Healthcare Llc | Devices and methods for integrated continuous production of biological molecules |
| WO2006138143A1 (en) | 2005-06-15 | 2006-12-28 | Amprotein Corporation | Suspension culture vessels |
| ES2662589T3 (es) | 2005-06-15 | 2018-04-09 | Zhejiang Jinyishengshi Bioengineering Co., Ltd. | Recipientes para cultivo en suspensión |
| WO2007106868A2 (en) * | 2006-03-14 | 2007-09-20 | University Of Rochester | Cell culture devices having ultrathin porous membrane and uses thereof |
| US20080206819A1 (en) | 2006-08-21 | 2008-08-28 | Mary Tsao | Intensified Perfusion Production Method |
| US20080207487A1 (en) | 2006-11-02 | 2008-08-28 | Neose Technologies, Inc. | Manufacturing process for the production of polypeptides expressed in insect cell-lines |
| US8058027B2 (en) | 2007-01-08 | 2011-11-15 | Millipore Corporation | Cell culture methods for producing recombinant proteins in the presence of reduced levels of one or more contaminants |
| WO2008106515A1 (en) * | 2007-02-27 | 2008-09-04 | The Board Of Trustees Of The University Of Illinois | Insert device for multiwell plate |
| JP5467415B2 (ja) | 2007-03-02 | 2014-04-09 | ベーリンガー インゲルハイム ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト | タンパク質製造の改良 |
| CN101678244B (zh) | 2007-04-17 | 2013-06-19 | 深度控股有限公司 | 用于连续膜吸附的方法和装置 |
| TW200902708A (en) | 2007-04-23 | 2009-01-16 | Wyeth Corp | Methods of protein production using anti-senescence compounds |
| US9109193B2 (en) | 2007-07-30 | 2015-08-18 | Ge Healthcare Bio-Sciences Corp. | Continuous perfusion bioreactor system |
| EP2188371B1 (en) | 2007-08-09 | 2017-12-20 | Wyeth LLC | Use of perfusion to enhance production of fed-batch cell culture in bioreactors |
| WO2009034186A2 (en) | 2007-09-13 | 2009-03-19 | Helmholtz-Zentrum für Infektionsforschung GmbH | Process for cell cultivation |
| US20090233334A1 (en) | 2008-03-11 | 2009-09-17 | Excellgene Sa | Cell cultivation and production of recombinant proteins by means of an orbital shake bioreactor system with disposable bags at the 1,500 liter scale |
| DE102008019691A1 (de) * | 2008-04-15 | 2009-10-29 | Technische Universität Ilmenau | Teilaktives mikrofluidisches System für die 3D-Zellkultivierung sowie Verfahren zu dessen Perfusion |
| US8096985B2 (en) | 2008-05-07 | 2012-01-17 | Guided Delivery Systems Inc. | Deflectable guide |
| US20100076380A1 (en) | 2008-06-16 | 2010-03-25 | Amprotein Corporation | Bioreactors |
| JP2012506257A (ja) * | 2008-10-22 | 2012-03-15 | バイオベスト インターナショナル インコーポレイテッド | 細胞および細胞由来生成物の産生のための、灌流バイオリアクター、細胞培養システム、および方法 |
| SG174435A1 (en) * | 2009-03-26 | 2011-10-28 | Agency Science Tech & Res | Apparatus for cell or tissue culture |
| US8728479B2 (en) | 2009-03-31 | 2014-05-20 | The Trustees Of The University Of Pennsylvania | Antigen-binding proteins comprising recombinant protein scaffolds |
| CN101875917B (zh) | 2009-04-28 | 2012-07-04 | 北京清大天一科技有限公司 | 生物反应器微载体培养动物细胞生产猪瘟疫苗的方法 |
| JP2012531930A (ja) | 2009-07-06 | 2012-12-13 | ジェネンテック, インコーポレイテッド | 真核生物細胞の培養方法 |
| WO2011107519A2 (fr) * | 2010-03-02 | 2011-09-09 | Universite Technologie De Compiegne - Utc | Boite multi-reacteurs pour culture cellulaire dynamique |
| CN201933090U (zh) | 2010-11-22 | 2011-08-17 | 朱学仁 | 细胞微载体灌注培养截留装置 |
| JP2013544524A (ja) | 2010-12-06 | 2013-12-19 | ターポン バイオシステムズ,インコーポレイテッド | 生物学的生成物の連続プロセス法 |
| SG191745A1 (en) | 2011-01-17 | 2013-08-30 | Hoffmann La Roche | Separation apparatus and use thereof |
| KR101741650B1 (ko) | 2011-03-22 | 2017-05-31 | 가부시키가이샤 도카이히트 | 현미경 관찰용 배양장치 및 그 사용 방법 |
| AU2012252305B2 (en) | 2011-05-12 | 2017-02-02 | Probiogen Ag | Enhancement of protein production yield mediated by a fast shuttling cdc42 gtpase |
| KR101662412B1 (ko) | 2011-07-01 | 2016-10-04 | 암젠 인크 | 포유동물 세포 배양 |
| US20140177151A1 (en) * | 2011-07-15 | 2014-06-26 | Panasonic Corporation | Mobile terminal |
| AR089231A1 (es) | 2011-12-15 | 2014-08-06 | Amgen Inc | Metodo de floculacion |
| EP2620561B1 (en) | 2012-01-30 | 2014-12-31 | Dannrup, Neils | A device and a method for filtering stormwater |
| US20150004686A1 (en) * | 2012-02-02 | 2015-01-01 | Corning Incorporated | Automatic continuous perfusion cell culture microplate consumables |
| SG10201607963SA (en) * | 2012-04-01 | 2016-11-29 | Emd Millipore Corp | Cell culture and gradient migration assay method and devices |
| US9946845B2 (en) | 2012-10-02 | 2018-04-17 | Rxsafe Llc | System and method for filling and dispensing orders |
| AU2013334602B2 (en) * | 2012-10-23 | 2018-05-31 | Genzyme Corporation | Perfusion culturing methods and uses thereof |
| ES2717927T3 (es) | 2013-02-22 | 2019-06-26 | Genzyme Corp | Procedimientos de cultivo por perfusión de microportadores y usos de los mismos |
| WO2014130872A2 (en) | 2013-02-22 | 2014-08-28 | Genzyme Corporation | Microcarrier perfusion culturing methods and uses thereof |
| CN118388581A (zh) | 2013-03-08 | 2024-07-26 | 建新公司 | 治疗性蛋白药物物质的整合连续制造 |
| JP6742902B2 (ja) | 2013-03-15 | 2020-08-19 | ジェンザイム・コーポレーション | 高密度細胞バンキングの方法 |
| US9481901B2 (en) * | 2013-05-30 | 2016-11-01 | Amgen Inc. | Methods for increasing mannose content of recombinant proteins |
| KR20230142653A (ko) | 2013-09-16 | 2023-10-11 | 젠자임 코포레이션 | 세포 배양물을 가공하는 방법 및 시스템 |
| EP2881622A1 (de) | 2013-12-05 | 2015-06-10 | Continental Automotive GmbH | Aktuator |
| JP2017500017A (ja) | 2013-12-20 | 2017-01-05 | バイオジェン・エムエイ・インコーポレイテッドBiogen MA Inc. | 生物薬剤フェドバッチ生産能力及び生産物品質を改善するための灌流シード培養の使用 |
| TWI709569B (zh) | 2014-01-17 | 2020-11-11 | 美商健臻公司 | 無菌層析樹脂及其用於製造方法的用途 |
| TWI671312B (zh) | 2014-01-17 | 2019-09-11 | 美商健臻公司 | 無菌層析法及製法 |
| SG10202113019XA (en) | 2014-06-04 | 2021-12-30 | Amgen Inc | Methods for harvesting mammalian cell cultures |
| TW202204596A (zh) | 2014-06-06 | 2022-02-01 | 美商健臻公司 | 灌注培養方法及其用途 |
| TWI707949B (zh) | 2014-06-09 | 2020-10-21 | 美商健臻公司 | 種子罐培養法(seed train processes)及其用途 |
| CN104480897B (zh) | 2014-11-28 | 2017-01-04 | 上海市政工程设计研究总院(集团)有限公司 | 陆域占地少应用范围广的防汛墙 |
| CN104450597B (zh) | 2014-12-10 | 2020-07-28 | 青岛农业大学 | 一种石油降解菌固体菌剂的制备方法及由其制备的固体菌剂修复石油污染的土壤的方法 |
| CA3225136A1 (en) | 2014-12-22 | 2016-06-30 | Genzyme Corporation | Methods of culturing a mammalian cell |
-
2015
- 2015-06-04 TW TW110135269A patent/TW202204596A/zh unknown
- 2015-06-04 TW TW104118071A patent/TWI743024B/zh not_active IP Right Cessation
- 2015-06-05 US US14/732,325 patent/US11060058B2/en active Active
- 2015-06-05 CN CN201580042017.6A patent/CN106795495A/zh active Pending
- 2015-06-05 KR KR1020177000144A patent/KR102479281B1/ko active Active
- 2015-06-05 KR KR1020227044019A patent/KR102611855B1/ko active Active
- 2015-06-05 MX MX2016016142A patent/MX2016016142A/es unknown
- 2015-06-05 SG SG11201610167WA patent/SG11201610167WA/en unknown
- 2015-06-05 RU RU2016152238A patent/RU2708919C2/ru active
- 2015-06-05 WO PCT/US2015/034494 patent/WO2015188106A2/en not_active Ceased
- 2015-06-05 SG SG10202008131WA patent/SG10202008131WA/en unknown
- 2015-06-05 BR BR112016028512A patent/BR112016028512A8/pt not_active Application Discontinuation
- 2015-06-05 RU RU2019138327A patent/RU2733539C2/ru active
- 2015-06-05 JP JP2016571259A patent/JP6915992B2/ja active Active
- 2015-06-05 CA CA2951255A patent/CA2951255A1/en not_active Abandoned
- 2015-06-05 AU AU2015269184A patent/AU2015269184B2/en not_active Ceased
- 2015-06-05 EP EP15731177.0A patent/EP3152293B1/en active Active
- 2015-06-05 ES ES15731177T patent/ES3040723T3/es active Active
-
2016
- 2016-12-05 IL IL249384A patent/IL249384A0/en unknown
- 2016-12-06 MX MX2020009670A patent/MX2020009670A/es unknown
-
2020
- 2020-09-22 RU RU2020131199A patent/RU2020131199A/ru unknown
-
2021
- 2021-06-25 US US17/358,889 patent/US12006510B2/en active Active
- 2021-07-13 AU AU2021205004A patent/AU2021205004A1/en not_active Abandoned
- 2021-07-15 JP JP2021116795A patent/JP7350810B2/ja active Active
-
2023
- 2023-06-23 JP JP2023102970A patent/JP7769663B2/ja active Active
-
2024
- 2024-05-06 US US18/656,253 patent/US12378517B2/en active Active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2016016142A (es) | Metodos de cultivo por perfusion y usos de los mismos. | |
| IL284235A (en) | Kits and methods for preparing a microfluidic device for cell culture | |
| MX2021008142A (es) | Metodos para cosechar cultivos de celulas de mamifero. | |
| IL249828A0 (en) | Limbal stem cells of cultured mammals, methods of their creation and uses thereof | |
| TR201904270T4 (tr) | Tanımlı koşullar altında insan pluripotent kök hücrelerinin hematoendotelyal farklılaşması için yöntemler ve materyaller. | |
| PL2992079T3 (pl) | Artykuł studzienkowy i urządzenie płytki perfuzyjnej do hodowli komórek sferoidalnych | |
| MX2015010943A (es) | Metodos de cultivo por perfusión con microportadores y usos de los mismos. | |
| MX2019009189A (es) | Metodos de cultivo por perfusion con microportadores y usos de los mismos. | |
| EP3263697A4 (en) | Culture medium for culturing mesenchymal stem cell, method for culturing mesenchymal stem cell, and mesenchymal stem cell | |
| EP3141596A4 (en) | Multi-chamber culture vessel and cell culturing method | |
| HK1220404A1 (zh) | 用於细胞培养的细胞外基质组合物珠粒 | |
| EP3153572A4 (en) | Closed culture vessel for anchorage-dependent cells | |
| ITUB20151992A1 (it) | Piastra multi-pozzetto per colture cellulari | |
| EP3162892A4 (en) | Method for culturing adhesive cells, culture vessel, and method for producing protein | |
| MX2021001981A (es) | Metodos para preparar un poloxamero para usar en medio de cultivo celular. | |
| MX2022000516A (es) | Metodos relacionados con celulas pluripotentes. | |
| EP3183333A4 (en) | Primary mammalian cell culture systems and methods | |
| IN2014DE01009A (es) | ||
| ZA202310780B (en) | Compositions and methods for enhanced gene expression | |
| KR102204519B9 (ko) | 세포 배양 플레이트 | |
| AU201611868S (en) | Microbiological Culture Plate Output Stack |