MX357365B - Virus del herpes aviar recombinantes multivalentes y vacunas para inmunizar especies aviares. - Google Patents
Virus del herpes aviar recombinantes multivalentes y vacunas para inmunizar especies aviares.Info
- Publication number
- MX357365B MX357365B MX2014011754A MX2014011754A MX357365B MX 357365 B MX357365 B MX 357365B MX 2014011754 A MX2014011754 A MX 2014011754A MX 2014011754 A MX2014011754 A MX 2014011754A MX 357365 B MX357365 B MX 357365B
- Authority
- MX
- Mexico
- Prior art keywords
- avian
- vaccines
- immunizing
- herpes viruses
- multivalent recombinant
- Prior art date
Links
- 241000271566 Aves Species 0.000 title abstract 3
- 241001529453 unidentified herpesvirus Species 0.000 title abstract 2
- 230000003053 immunization Effects 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 101150093191 RIR1 gene Proteins 0.000 abstract 2
- 101150048066 UL45 gene Proteins 0.000 abstract 2
- 108091092724 Noncoding DNA Proteins 0.000 abstract 1
- 101150102071 TRX1 gene Proteins 0.000 abstract 1
- 101150104684 UL44 gene Proteins 0.000 abstract 1
- 101150117989 UL46 gene Proteins 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 101150002378 gC gene Proteins 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
- A61K39/17—Newcastle disease virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
- C12N2710/16321—Viruses as such, e.g. new isolates, mutants or their genomic sequences
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
- C12N2710/16334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
- C12N2710/16341—Use of virus, viral particle or viral elements as a vector
- C12N2710/16343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/10011—Birnaviridae
- C12N2720/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
- C12N2760/18134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pulmonology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
La presente invención se refiere a un virus del herpes aviar recombinante, que comprende al menos dos secuencias de nucleótidos recombinantes, codificando cada secuencia de nucleótidos recombinante un péptido antigénico distinto, en donde dichas al menos dos secuencias de nucleótidos recombinantes se insertan en regiones no codificantes distintas del genoma viral seleccionadas entre la región localizada entre UL44 y UL45, la región localizada entre UL45 y UL46, la región localizada entre US10 y SORF3, la región localizada entre SORF3 y US2.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20120305390 EP2644702A1 (en) | 2012-03-30 | 2012-03-30 | Multivalent recombinant avian herpes virus and vaccine for immunizing avian species |
| PCT/EP2013/056839 WO2013144355A1 (en) | 2012-03-30 | 2013-03-29 | Multivalent recombinant avian herpes viruses and vaccines for immunizing avian species |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2014011754A MX2014011754A (es) | 2014-11-26 |
| MX357365B true MX357365B (es) | 2018-07-05 |
Family
ID=48040245
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014011754A MX357365B (es) | 2012-03-30 | 2013-03-29 | Virus del herpes aviar recombinantes multivalentes y vacunas para inmunizar especies aviares. |
Country Status (22)
| Country | Link |
|---|---|
| US (6) | US10251951B2 (es) |
| EP (4) | EP2644702A1 (es) |
| JP (2) | JP6505593B2 (es) |
| KR (1) | KR102070217B1 (es) |
| CN (2) | CN111733143A (es) |
| BR (1) | BR112014024094A2 (es) |
| CA (1) | CA2868132C (es) |
| CO (1) | CO7160021A2 (es) |
| ES (2) | ES2807952T3 (es) |
| HU (2) | HUE050602T2 (es) |
| MA (1) | MA37446B1 (es) |
| MX (1) | MX357365B (es) |
| MY (1) | MY173016A (es) |
| PE (2) | PE20191704A1 (es) |
| PH (2) | PH12014502162B1 (es) |
| PL (2) | PL3219802T3 (es) |
| PT (2) | PT2831246T (es) |
| RU (2) | RU2658439C2 (es) |
| TN (1) | TN2014000392A1 (es) |
| UA (1) | UA118335C2 (es) |
| WO (1) | WO2013144355A1 (es) |
| ZA (1) | ZA201406979B (es) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2644702A1 (en) * | 2012-03-30 | 2013-10-02 | Ceva Sante Animale | Multivalent recombinant avian herpes virus and vaccine for immunizing avian species |
| EP2845904A1 (en) | 2013-09-06 | 2015-03-11 | Ceva Sante Animale | Recombinant Marek's disease viruses and uses thereof |
| CN104120110B (zh) * | 2014-07-11 | 2017-01-18 | 中国农业科学院哈尔滨兽医研究所 | 表达增强型绿色荧光蛋白基因的鸭瘟病毒重组疫苗株及其构建方法和应用 |
| CN104212802B (zh) * | 2014-09-25 | 2017-09-12 | 中国人民解放军第二军医大学东方肝胆外科医院 | 一种肿瘤细胞广谱高活性启动子及其用途 |
| AR103245A1 (es) | 2014-12-24 | 2017-04-26 | Intervet Int Bv | Vacuna vectorial basada en hvt (herpes virus de los pavos) frente a nd (enfermedad de newcastle) - ibd (enfermedad de gumboro) mejorada |
| EP3334833A4 (en) * | 2015-08-10 | 2019-04-24 | The Texas A&M University System | RECOMBINANT TURKEY HERPESVIRUS VACCINES AND USES THEREOF |
| EP3471766B1 (en) | 2016-06-17 | 2022-12-14 | Intervet International B.V. | Recombinant non-pathogenic marek's disease virus constructs encoding infectious laryngotracheitis virus and infectious bursal disease virus antigens |
| CN106350475A (zh) * | 2016-08-26 | 2017-01-25 | 江苏省农业科学院 | 一种新型火鸡疱疹病毒的细菌人工染色体、构建方法与应用 |
| CN117357642A (zh) | 2016-12-14 | 2024-01-09 | 勃林格殷格翰动物保健美国公司 | 表达禽病原体的多种抗原的重组hvt载体及其用途 |
| CN106929483B (zh) * | 2017-01-19 | 2020-09-25 | 北京邦卓生物科技有限公司 | 表达鸡新城疫病毒f基因的重组火鸡疱疹病毒的构建及其应用 |
| BR112020007213A2 (pt) * | 2017-10-12 | 2020-10-13 | Intervet International B.V. | construtos de vírus da doença de marek não patogênico recombinante que codificam múltiplos antígenos heterólogos |
| CN107815469A (zh) * | 2017-10-16 | 2018-03-20 | 北京市农林科学院 | 一种重组火鸡疱疹病毒及其制备方法 |
| CN108060141B (zh) * | 2017-12-14 | 2021-05-28 | 天津瑞普生物技术股份有限公司 | Vp2基因和np基因重组腺病毒及其应用 |
| CN109402071B (zh) * | 2018-11-08 | 2021-04-27 | 中国农业大学 | 一种表达h9n2亚型禽流感病毒h9蛋白的重组火鸡疱疹病毒 |
| US20220040287A1 (en) * | 2018-12-21 | 2022-02-10 | Ceva Sante Animale | Recombinant avian herpes viruses containing multiple foreign genes |
| CN113347992A (zh) | 2018-12-27 | 2021-09-03 | 法国诗华大药厂 | 重组病毒和其用途 |
| US11464849B2 (en) | 2019-09-11 | 2022-10-11 | Zoetis Services Llc | Recombinant herpesvirus of turkey vectors expressing antigens of avian pathogens and uses thereof |
| CN110684744A (zh) * | 2019-10-22 | 2020-01-14 | 青岛易邦生物工程有限公司 | 一种表达鸡传染性法氏囊病病毒vp2基因的重组火鸡疱疹病毒株 |
| CN114828882A (zh) | 2019-12-20 | 2022-07-29 | 英特维特国际股份有限公司 | 多价hvt载体疫苗 |
| CN116472057A (zh) | 2020-06-17 | 2023-07-21 | 勃林格殷格翰动物保健有限公司 | 表达流感血凝素的重组hvt载体和免疫原性组合物,以及其生产和用途 |
| CN116457461A (zh) * | 2020-10-15 | 2023-07-18 | 法国诗华动物保健公司 | 重组hvt及其用途 |
| JP2024501943A (ja) | 2020-12-24 | 2024-01-17 | インターベット インターナショナル ベー. フェー. | 多価hvtベクターワクチン |
| US20250352642A1 (en) | 2022-05-05 | 2025-11-20 | Intervet Inc. | New multivalent hvt vector vaccine |
| JP2026508736A (ja) | 2022-11-18 | 2026-03-12 | セヴァ サンテ アニマレ | 組換えマレック病ウイルス及びその使用 |
| WO2025046412A2 (en) | 2023-08-25 | 2025-03-06 | Boehringer Ingelheim Vetmedica Gmbh | Hvt aiv vectors and uses thereof |
| CN120555370A (zh) * | 2024-02-29 | 2025-08-29 | 诗华动保科技(杭州)有限公司 | 重组hvt及其应用 |
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| JP2009195136A (ja) | 2008-02-20 | 2009-09-03 | Nippon Zeon Co Ltd | 新規な組換え七面鳥ヘルペスウイルス、及びそれを利用した家禽用ワクチン |
| BRPI0918806B1 (pt) * | 2008-09-05 | 2019-02-05 | Ceva Sante Animale Sa | Composição de vacina compreendendo quitosana e antígeno do vírus de doença de newcastle (nvd) adaptada à administração ocular em ave, uso de quitosana e de nvd paraaumentar resposta imune em ave, bem como kit de vacinação de aves |
| WO2010119112A1 (en) * | 2009-04-15 | 2010-10-21 | Ceva Sante Animale | Recombinant avian herpes virus vectors and vaccine for immunizing waterfowl species |
| EP2768964B1 (en) * | 2011-10-21 | 2018-10-10 | Intervet International B.V. | Recombinant non-pathogenic marek's disease virus constructs encoding infectious laryngotracheitis virus and newcastle disease virus antigens |
| EP3251691B1 (en) | 2011-11-30 | 2019-11-20 | Boehringer Ingelheim Animal Health USA Inc. | Recombinant hvt vectors expressing antigens of avian pathogens and uses thereof |
| EP2644702A1 (en) | 2012-03-30 | 2013-10-02 | Ceva Sante Animale | Multivalent recombinant avian herpes virus and vaccine for immunizing avian species |
| EP2845904A1 (en) | 2013-09-06 | 2015-03-11 | Ceva Sante Animale | Recombinant Marek's disease viruses and uses thereof |
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2012
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2013
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