MA20150281A2 - Virus herpès aviaire recombinant multivalents et vaccins pour immuniser les espèces aviaires - Google Patents

Virus herpès aviaire recombinant multivalents et vaccins pour immuniser les espèces aviaires

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Publication number
MA20150281A2
MA20150281A2 MA37446A MA37446A MA20150281A2 MA 20150281 A2 MA20150281 A2 MA 20150281A2 MA 37446 A MA37446 A MA 37446A MA 37446 A MA37446 A MA 37446A MA 20150281 A2 MA20150281 A2 MA 20150281A2
Authority
MA
Morocco
Prior art keywords
avian
vaccines
immunize
herpes virus
region
Prior art date
Application number
MA37446A
Other languages
English (en)
Other versions
MA37446B1 (fr
Inventor
Ayumi Fujisawa
Mayumi Kubomura
Sakiko Saeki
Shuji Saito
Original Assignee
Ceva Sante Animale
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48040245&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA20150281(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ceva Sante Animale filed Critical Ceva Sante Animale
Publication of MA20150281A2 publication Critical patent/MA20150281A2/fr
Publication of MA37446B1 publication Critical patent/MA37446B1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/245—Herpetoviridae, e.g. herpes simplex virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
    • A61K39/17—Newcastle disease virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
    • C12N2710/16321—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
    • C12N2710/16334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
    • C12N2710/16341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/16343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/10011—Birnaviridae
    • C12N2720/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
    • C12N2760/18134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La présente invention concerne un virus de l'herpès aviaire recombinant, qui comprend au moins deux séquences nucléotidiques de recombinaison, chaque séquence nucléotidique recombinante codant un peptide antigénique distinct, dans lequel ladite au moins deux séquences nucléotidiques de recombinaison distinctes sont insérées dans la région non codante du génome viral choisi parmi la région située entre ul44 et ul45, la région située entre ul45 et ul46, la région située entre us10 sorf3, et la région située entre sorf3 et us2.
MA37446A 2012-03-30 2014-10-22 Virus herpès aviaire recombinant multivalents et vaccins pour immuniser les espèces aviaires MA37446B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20120305390 EP2644702A1 (fr) 2012-03-30 2012-03-30 Virus herpès aviaire recombinant multivalents et vaccin pour immuniser les espèces aviaires
PCT/EP2013/056839 WO2013144355A1 (fr) 2012-03-30 2013-03-29 Virus herpès aviaire recombinant multivalents et vaccins pour immuniser les espèces aviaires

Publications (2)

Publication Number Publication Date
MA20150281A2 true MA20150281A2 (fr) 2015-08-31
MA37446B1 MA37446B1 (fr) 2016-10-31

Family

ID=48040245

Family Applications (1)

Application Number Title Priority Date Filing Date
MA37446A MA37446B1 (fr) 2012-03-30 2014-10-22 Virus herpès aviaire recombinant multivalents et vaccins pour immuniser les espèces aviaires

Country Status (22)

Country Link
US (6) US10251951B2 (fr)
EP (4) EP2644702A1 (fr)
JP (2) JP6505593B2 (fr)
KR (1) KR102070217B1 (fr)
CN (2) CN111733143A (fr)
BR (1) BR112014024094A2 (fr)
CA (1) CA2868132C (fr)
CO (1) CO7160021A2 (fr)
ES (2) ES2807952T3 (fr)
HU (2) HUE050602T2 (fr)
MA (1) MA37446B1 (fr)
MX (1) MX357365B (fr)
MY (1) MY173016A (fr)
PE (2) PE20150334A1 (fr)
PH (2) PH12014502162A1 (fr)
PL (2) PL3219802T3 (fr)
PT (2) PT3219802T (fr)
RU (2) RU2658439C2 (fr)
TN (1) TN2014000392A1 (fr)
UA (1) UA118335C2 (fr)
WO (1) WO2013144355A1 (fr)
ZA (1) ZA201406979B (fr)

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EP2644702A1 (fr) 2012-03-30 2013-10-02 Ceva Sante Animale Virus herpès aviaire recombinant multivalents et vaccin pour immuniser les espèces aviaires
EP2845904A1 (fr) * 2013-09-06 2015-03-11 Ceva Sante Animale Virus de l'herpes de la volaille recombinants et leurs utilisations
CN104120110B (zh) * 2014-07-11 2017-01-18 中国农业科学院哈尔滨兽医研究所 表达增强型绿色荧光蛋白基因的鸭瘟病毒重组疫苗株及其构建方法和应用
CN104212802B (zh) * 2014-09-25 2017-09-12 中国人民解放军第二军医大学东方肝胆外科医院 一种肿瘤细胞广谱高活性启动子及其用途
AR103245A1 (es) 2014-12-24 2017-04-26 Intervet Int Bv Vacuna vectorial basada en hvt (herpes virus de los pavos) frente a nd (enfermedad de newcastle) - ibd (enfermedad de gumboro) mejorada
WO2017027324A1 (fr) * 2015-08-10 2017-02-16 The Texas A&M University System Vaccins du virus de l'herpès de dinde recombinant et utilisations de celui-ci
ES2935643T3 (es) 2016-06-17 2023-03-08 Intervet Int Bv Construcciones de virus de la enfermedad de Marek no patógeno recombinante que codifican antígenos del virus de la laringotraqueítis infecciosa y del virus de la bursitis infecciosa
CN106350475A (zh) * 2016-08-26 2017-01-25 江苏省农业科学院 一种新型火鸡疱疹病毒的细菌人工染色体、构建方法与应用
CN117357641A (zh) 2016-12-14 2024-01-09 勃林格殷格翰动物保健美国公司 表达禽病原体的多种抗原的重组hvt载体及其用途
CN106929483B (zh) * 2017-01-19 2020-09-25 北京邦卓生物科技有限公司 表达鸡新城疫病毒f基因的重组火鸡疱疹病毒的构建及其应用
JP7721269B2 (ja) 2017-10-12 2025-08-12 インターベット インターナショナル ベー． フェー． 複数の異種抗原をコードする組換え非病原性マレック病ウイルス構築物
CN107815469A (zh) * 2017-10-16 2018-03-20 北京市农林科学院 一种重组火鸡疱疹病毒及其制备方法
CN108060141B (zh) * 2017-12-14 2021-05-28 天津瑞普生物技术股份有限公司 Vp2基因和np基因重组腺病毒及其应用
CN109402071B (zh) * 2018-11-08 2021-04-27 中国农业大学 一种表达h9n2亚型禽流感病毒h9蛋白的重组火鸡疱疹病毒
JP7590329B2 (ja) 2018-12-21 2024-11-26 セヴァ サンテ アニマレ 複数の外来遺伝子を含む組換えトリヘルペスウイルス
WO2020136220A1 (fr) 2018-12-27 2020-07-02 Ceva Sante Animale Virus recombinants et leurs utilisations
KR102850522B1 (ko) 2019-09-11 2025-08-26 조에티스 서비시즈 엘엘씨 조류 병원체의 항원을 발현하는 재조합 칠면조 헤르페스바이러스 벡터 및 이의 용도
CN110684744A (zh) * 2019-10-22 2020-01-14 青岛易邦生物工程有限公司 一种表达鸡传染性法氏囊病病毒vp2基因的重组火鸡疱疹病毒株
US12589147B2 (en) 2019-12-20 2026-03-31 Intervet Inc. Multivalent HVT vector vaccine
EP4168043A1 (fr) 2020-06-17 2023-04-26 Boehringer Ingelheim Vetmedica GmbH Vecteurs hvt recombinants exprimant l'hémagglutinine de la grippe et compositions immunogènes, et leur fabrication et leurs utilisations
US20230372474A1 (en) * 2020-10-15 2023-11-23 Ceva Sante Animale Recombinant hvt and uses thereof
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JP2025515050A (ja) 2022-05-05 2025-05-13 インターベット インターナショナル ベー． フェー． 新規多価ｈｖｔベクターワクチン
EP4619031A1 (fr) 2022-11-18 2025-09-24 Ceva Sante Animale Virus recombinant de la maladie de marek et ses utilisations
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EP2644702A1 (fr) 2012-03-30 2013-10-02 Ceva Sante Animale Virus herpès aviaire recombinant multivalents et vaccin pour immuniser les espèces aviaires
EP2845904A1 (fr) 2013-09-06 2015-03-11 Ceva Sante Animale Virus de l'herpes de la volaille recombinants et leurs utilisations

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CA2868132A1 (fr) 2013-10-03
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