MX9701838A - Compuesto de poliamina para tratar desodorantes proliferativos vasculares. - Google Patents

Compuesto de poliamina para tratar desodorantes proliferativos vasculares.

Info

Publication number
MX9701838A
MX9701838A MX9701838A MX9701838A MX9701838A MX 9701838 A MX9701838 A MX 9701838A MX 9701838 A MX9701838 A MX 9701838A MX 9701838 A MX9701838 A MX 9701838A MX 9701838 A MX9701838 A MX 9701838A
Authority
MX
Mexico
Prior art keywords
proliferative disorders
polyamine compounds
vascular proliferative
treating vascular
treating
Prior art date
Application number
MX9701838A
Other languages
English (en)
Inventor
Donald Hupe
Joan Alexis Keiser
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of MX9701838A publication Critical patent/MX9701838A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Las poliamina inhiben la proliferacion de musculos lisos vasculares y así son utiles para tratar y prevenir desordenes proliferativos vasculares como la restenosis después de la angioplastia de balon.
MX9701838A 1994-10-25 1995-09-14 Compuesto de poliamina para tratar desodorantes proliferativos vasculares. MX9701838A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/329,588 US5516807A (en) 1994-10-25 1994-10-25 Method for treating vascular proliferative disorders following balloon angioplasty
PCT/US1995/011680 WO1996012480A1 (en) 1994-10-25 1995-09-14 Polyamine compounds for treating vascular proliferative disorders

Publications (1)

Publication Number Publication Date
MX9701838A true MX9701838A (es) 1997-06-28

Family

ID=23286110

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9701838A MX9701838A (es) 1994-10-25 1995-09-14 Compuesto de poliamina para tratar desodorantes proliferativos vasculares.

Country Status (12)

Country Link
US (1) US5516807A (es)
EP (1) EP0786991B1 (es)
JP (1) JPH10507752A (es)
AT (1) ATE198706T1 (es)
CA (1) CA2198914A1 (es)
DE (1) DE69519937T2 (es)
DK (1) DK0786991T3 (es)
ES (1) ES2155531T3 (es)
GR (1) GR3035725T3 (es)
MX (1) MX9701838A (es)
PT (1) PT786991E (es)
WO (1) WO1996012480A1 (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5811447A (en) 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5770609A (en) 1993-01-28 1998-06-23 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US6251920B1 (en) 1993-05-13 2001-06-26 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US6306421B1 (en) 1992-09-25 2001-10-23 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6663881B2 (en) 1993-01-28 2003-12-16 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5981568A (en) 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US7611533B2 (en) * 1995-06-07 2009-11-03 Cook Incorporated Coated implantable medical device
CA2223595C (en) * 1995-06-07 2008-08-05 Neorx Corporation Prevention and treatment of cardiovascular pathologies with tamoxifen analogues
CA2264745C (en) * 1996-09-13 2003-11-11 University Of Florida Research Foundation, Inc. Method of inhibiting biosynthesis of eif5a
US6083991A (en) * 1997-06-04 2000-07-04 University Of Florida Research Foundation, Inc. Anti-arrhythmic composition and methods of treatment
US7087648B1 (en) 1997-10-27 2006-08-08 The Regents Of The University Of California Methods for modulating macrophage proliferation using polyamine analogs
US8198334B2 (en) * 1997-10-27 2012-06-12 Pathologica Llc Methods for modulating macrophage proliferation in ocular disease using polyamine analogs
DE60029944T2 (de) 1999-04-30 2007-04-05 Cellgate, Inc., Redwood City Polyamine und ihre therapeutische verwendung
US6649587B1 (en) 1999-04-30 2003-11-18 Slil Biomedical Corporation Polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases
US6482943B1 (en) * 1999-04-30 2002-11-19 Slil Biomedical Corporation Quinones as disease therapies
IL146126A0 (en) * 1999-04-30 2002-07-25 Slil Biomedical Corp Novel polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases
US7312244B2 (en) * 1999-04-30 2007-12-25 Cellgate, Inc. Polyamine analog-amino acid conjugates useful as anticancer agents
US6613083B2 (en) 2001-05-02 2003-09-02 Eckhard Alt Stent device and method
CA2469354A1 (en) * 2001-12-07 2003-06-19 Slil Biomedical Corporation Cycloalkyl substituted polyamines for cancer therapy and methods of synthesis therefor
JP2004189714A (ja) * 2002-12-09 2004-07-08 Rasanen Tiina-Liisa すい臓炎の治療と予防ならびに肝臓再生機能の誘導のための薬剤
BRPI0517551A (pt) * 2004-10-04 2008-10-14 Cellgate Inc análogos de poliamina como agentes terapêuticos para doenças oculares
US20070232677A1 (en) * 2006-03-14 2007-10-04 Marton Laurence J Treatment and prevention of vascular hyperplasia using polyamine and polyamine analog compounds
US8709419B2 (en) * 2010-08-17 2014-04-29 Hoffmann-La Roche, Inc. Combination therapy
US9295669B2 (en) 2010-12-14 2016-03-29 Hoffman La-Roche Inc. Combination therapy for proliferative disorders

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS606348B2 (ja) * 1976-03-31 1985-02-18 三菱化学株式会社 新規ポリアミン類
JPS58135809A (ja) * 1982-02-05 1983-08-12 Fujisawa Pharmaceut Co Ltd 抗炎症・抗リウマチ剤
US4507321A (en) * 1982-02-17 1985-03-26 The Research Foundation Of State University Of New York Epithelial cell growth regulating composition containing polyamines and a method of using same
JPS606348A (ja) * 1983-06-09 1985-01-14 ケルベル・アクチエンゲゼルシヤフト 回転研削工具の支承装置
NZ212053A (en) * 1984-05-17 1988-02-29 Merrell Dow Pharma Polyamine containing pharmaceutical compositions for treating neoplasms
US5091576A (en) * 1986-12-02 1992-02-25 University Of Florida Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives
AU602186B2 (en) * 1987-02-03 1990-10-04 Merrell Dow Pharmaceuticals Inc. Novel polyamine derivatives
AU628174B2 (en) * 1989-05-23 1992-09-10 Merrell Dow Pharmaceuticals Inc. A method of potentiating cell-mediated immunity utilizing polyamine derivatives

Also Published As

Publication number Publication date
EP0786991A1 (en) 1997-08-06
WO1996012480A1 (en) 1996-05-02
US5516807A (en) 1996-05-14
DE69519937D1 (de) 2001-02-22
CA2198914A1 (en) 1996-05-02
ES2155531T3 (es) 2001-05-16
EP0786991B1 (en) 2001-01-17
PT786991E (pt) 2001-04-30
ATE198706T1 (de) 2001-02-15
GR3035725T3 (en) 2001-07-31
DK0786991T3 (da) 2001-03-19
JPH10507752A (ja) 1998-07-28
DE69519937T2 (de) 2001-06-07

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Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees