MY124548A - Synthetic polysaccharides, preparation method therefor and pharmaceutical compositons containing same - Google Patents

Synthetic polysaccharides, preparation method therefor and pharmaceutical compositons containing same

Info

Publication number
MY124548A
MY124548A MYPI97003269A MYPI19973269A MY124548A MY 124548 A MY124548 A MY 124548A MY PI97003269 A MYPI97003269 A MY PI97003269A MY PI19973269 A MYPI19973269 A MY PI19973269A MY 124548 A MY124548 A MY 124548A
Authority
MY
Malaysia
Prior art keywords
preparation
synthetic polysaccharides
region
method therefor
containing same
Prior art date
Application number
MYPI97003269A
Other languages
English (en)
Inventor
Pierre Alexandre Driguez
Philippe Duchaussoy
Petervan Der Grootenhuis
Jean Marc Herbert
Maurice Petitou
Boeckel Constant Van
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of MY124548A publication Critical patent/MY124548A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
MYPI97003269A 1996-07-19 1997-07-18 Synthetic polysaccharides, preparation method therefor and pharmaceutical compositons containing same MY124548A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9609116A FR2751334B1 (fr) 1996-07-19 1996-07-19 Polysaccharides synthetiques, procede pour leur preparation et compositions pharmaceutiques les contenant

Publications (1)

Publication Number Publication Date
MY124548A true MY124548A (en) 2006-06-30

Family

ID=9494266

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI97003269A MY124548A (en) 1996-07-19 1997-07-18 Synthetic polysaccharides, preparation method therefor and pharmaceutical compositons containing same

Country Status (35)

Country Link
US (1) US6534481B1 (id)
EP (1) EP0912613B1 (id)
JP (1) JP3345020B2 (id)
KR (1) KR100311857B1 (id)
CN (1) CN1200003C (id)
AR (1) AR008068A1 (id)
AT (1) ATE224917T1 (id)
AU (1) AU726679B2 (id)
BR (1) BR9710739B1 (id)
CA (1) CA2261597C (id)
CZ (1) CZ301009B6 (id)
DE (1) DE69715866T2 (id)
DK (1) DK0912613T3 (id)
EE (1) EE03929B1 (id)
ES (1) ES2184123T3 (id)
FR (1) FR2751334B1 (id)
HU (1) HU223691B1 (id)
ID (1) ID20604A (id)
IL (2) IL128018A0 (id)
IS (1) IS1968B (id)
MY (1) MY124548A (id)
NO (1) NO319682B1 (id)
NZ (1) NZ333721A (id)
PL (1) PL190397B1 (id)
PT (1) PT912613E (id)
RU (1) RU2167163C2 (id)
SA (1) SA99200037B1 (id)
SI (1) SI0912613T1 (id)
SK (1) SK284881B6 (id)
TR (1) TR199900114T2 (id)
TW (1) TW520376B (id)
UA (1) UA61921C2 (id)
WO (1) WO1998003554A1 (id)
YU (1) YU49247B (id)
ZA (1) ZA976340B (id)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2773804B1 (fr) * 1998-01-19 2000-02-18 Sanofi Sa Polysaccharides de synthese, procede pour leur preparation et compositions pharmaceutiques le contenant
FR2773801B1 (fr) 1998-01-19 2000-05-12 Sanofi Sa Nouveaux pentasaccharides, procedes pour leurs preparations et compositions pharmaceutiques les contenant
FR2814463B1 (fr) * 2000-09-22 2002-11-15 Sanofi Synthelabo Nouveaux polysaccharides a activite antithrombotique comprenant au moins une liaison covalente avec la biotine ou un derive de la biotine
US7138531B2 (en) * 2001-10-15 2006-11-21 Kemin Pharma B.V.B.A. Preparation and use of carbohydrate-based bicyclic ring structures with antimicrobial and cytostatic activity
DE602004028799D1 (en) * 2003-01-30 2010-10-07 Daiichi Sankyo Co Ltd Oligosaccharidderivat
UA81657C2 (ru) * 2003-03-04 2008-01-25 Орто-Макнейл Фармасьютикел, Инк. Способ получения противосудорожных производных топирамата
EP1574516A1 (en) * 2004-03-05 2005-09-14 Sanofi-Aventis Antithrombotic compound
US7563780B1 (en) * 2004-06-18 2009-07-21 Advanced Cardiovascular Systems, Inc. Heparin prodrugs and drug delivery stents formed therefrom
FR2874924B1 (fr) 2004-09-09 2006-12-01 Sanofi Aventis Sa Hexadecasaccharides biotinyles, leur preparation et leur utilisation therapeutique
TWI403334B (zh) * 2004-12-23 2013-08-01 Merck Sharp & Dohme 包含生物素殘基之抗血栓雙重抑制劑
TWI376234B (en) * 2005-02-01 2012-11-11 Msd Oss Bv Conjugates of a polypeptide and an oligosaccharide
HRP20110331T1 (hr) * 2005-10-10 2011-06-30 N.V. Organon Antikoagulantno-antitrombotski dvojni inhibitori, koji sadrže biotinski biljeg
IL181431A0 (en) * 2007-02-19 2007-07-04 Micha Shemer Fruit juice and puree with a lowered amount of available sugars
ES2584927T7 (es) 2007-10-16 2020-11-05 Progen Pg500 Series Pty Ltd Derivados de oligosacáridos sulfatados novedosos
RU2379684C2 (ru) * 2007-11-29 2010-01-20 Федеральное государственное учреждение "Федеральный центр сердца, крови и эндокринологии имени В.А. Алмазова Федерального агентства по высокотехнологичной медицинской помощи" Способ определения антитромботического эффекта ацетилсалициловой кислоты
CN102046781A (zh) 2008-05-30 2011-05-04 动量制药公司 糖结构以及制造和使用此类结构的方法
FR2935386B1 (fr) * 2008-08-26 2010-09-10 Sanofi Aventis Nouveaux polysaccharides a activite antithrombotique comprenant une liaion covalente avec une chaine amine
WO2011014793A2 (en) * 2009-07-31 2011-02-03 Reliable Biopharmaceutical Corporation Process for preparing fondaparinux sodium and intermediates useful in the synthesis thereof
FR2949115B1 (fr) 2009-08-14 2012-11-02 Sanofi Aventis OLIGOSACCHARIDES N-SULFATES ACTIVATEURS DES RECEPTEURS DES FGFs, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
FR2949114B1 (fr) 2009-08-14 2011-08-26 Sanofi Aventis OCTASACCHARIDES N-ACYLES ACTIVATEURS DES RECEPTEURS DES FGFs, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
US8420790B2 (en) 2009-10-30 2013-04-16 Reliable Biopharmaceutical Corporation Efficient and scalable process for the manufacture of Fondaparinux sodium
KR101682466B1 (ko) * 2010-02-01 2016-12-05 롯데정밀화학 주식회사 아세틸화 셀룰로오스 에테르 및 이를 포함하는 물품
EP2614089A1 (fr) 2010-09-10 2013-07-17 Sanofi-Aventis Polysaccharides biotinyles a activite antithrombotique et presentant une stabilite metabolique amelioree
FR2970969B1 (fr) 2011-01-27 2013-10-18 Sanofi Aventis Oligosaccharides 3-o-alkyles activateurs des recepteurs des fgfs, leur preparation et leur application en therapeutique
CN109134555B (zh) * 2017-06-15 2021-09-28 南京正大天晴制药有限公司 抗凝血的五糖类化合物及其制备方法和医药用途
CN109134553B (zh) * 2017-06-15 2021-09-28 南京正大天晴制药有限公司 抗凝血的五糖类化合物及其制备方法和医药用途
CN109134554B (zh) * 2017-06-15 2021-09-28 南京正大天晴制药有限公司 抗凝血的五糖类化合物及其制备方法和医药用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4801583A (en) 1982-01-15 1989-01-31 Choay S.A. Oligosaccharides and their biological applications
EP0300099A1 (en) 1987-07-20 1989-01-25 Akzo N.V. New pentasaccharides
US5378829A (en) 1990-04-23 1995-01-03 Akzo N.V. Sulfated glycosaminoglycanoid derivatives of the heparin and heparan sulfate type
US5382570A (en) 1990-04-23 1995-01-17 Akzo, N.V. Sulfated glycosaminoglycanoid derivatives of the dermatan sulfate and chondroitin sulfate type
CA2061370A1 (en) * 1991-03-13 1992-09-14 Markus Hosang Pharmaceutical preparations
IL102758A (en) 1991-08-23 1997-03-18 Akzo Nv Glycosaminoglycanoid derivatives, their preparation and pharmaceutical compositions comprising them
FR2704226B1 (fr) 1993-04-22 1995-07-21 Sanofi Elf 3-desoxy oligosaccharides, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
IT1270823B (it) * 1993-06-04 1997-05-13 Italfarmaco Spa Polisaccaridi ad elevata attivita' antitrombotica e anticoagulante
ES2147216T3 (es) 1993-09-01 2000-09-01 Akzo Nobel Nv Bisconjugados que comprenden dos sacaridos y un grupo de union.
FR2749849B1 (fr) * 1996-06-14 1998-09-04 Sanofi Sa Polysaccharides synthetiques, procede pour leur preparation et compositions pharmaceutiques les contenant

Also Published As

Publication number Publication date
YU49247B (sh) 2004-12-31
EP0912613A1 (fr) 1999-05-06
TR199900114T2 (xx) 1999-03-22
PL331259A1 (en) 1999-07-05
CA2261597C (fr) 2004-12-14
HUP9902287A3 (en) 2001-09-28
FR2751334A1 (fr) 1998-01-23
IL128018A0 (en) 1999-11-30
KR100311857B1 (ko) 2001-11-14
ZA976340B (en) 1999-01-22
IS4945A (is) 1999-01-18
NO990215L (no) 1999-03-18
ES2184123T3 (es) 2003-04-01
US6534481B1 (en) 2003-03-18
DK0912613T3 (da) 2003-01-27
YU1999A (sh) 2000-03-21
AU726679B2 (en) 2000-11-16
HUP9902287A1 (hu) 1999-10-28
SI0912613T1 (en) 2003-04-30
IS1968B (is) 2004-12-15
CA2261597A1 (fr) 1998-01-29
HK1019757A1 (en) 2000-02-25
AU3774797A (en) 1998-02-10
PT912613E (pt) 2003-01-31
EE9900015A (et) 1999-08-16
CN1200003C (zh) 2005-05-04
HU223691B1 (hu) 2004-12-28
EP0912613B1 (fr) 2002-09-25
SK284881B6 (sk) 2006-02-02
BR9710739A (pt) 1999-08-17
TW520376B (en) 2003-02-11
ATE224917T1 (de) 2002-10-15
NO319682B1 (no) 2005-09-05
CZ301009B6 (cs) 2009-10-14
ID20604A (id) 1999-01-21
NZ333721A (en) 2000-08-25
JP3345020B2 (ja) 2002-11-18
WO1998003554A1 (fr) 1998-01-29
UA61921C2 (uk) 2003-12-15
NO990215D0 (no) 1999-01-18
PL190397B1 (pl) 2005-12-30
RU2167163C2 (ru) 2001-05-20
JP2000500807A (ja) 2000-01-25
CN1228785A (zh) 1999-09-15
AR008068A1 (es) 1999-12-09
DE69715866T2 (de) 2003-05-28
DE69715866D1 (de) 2002-10-31
SK5399A3 (en) 2000-05-16
FR2751334B1 (fr) 1998-10-16
SA99200037B1 (ar) 2006-08-23
BR9710739B1 (pt) 2008-11-18
IL128018A (en) 2007-10-31
CZ16099A3 (cs) 1999-06-16
KR20000067909A (ko) 2000-11-25
EE03929B1 (et) 2002-12-16

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