MY126132A - Aminoquinazolines which inhibit signal transduction mediated by tyrosine kinases - Google Patents

Aminoquinazolines which inhibit signal transduction mediated by tyrosine kinases

Info

Publication number: MY126132A
Authority: MY; Malaysia
Prior art keywords: signal transduction; tyrosine kinases; aminoquinazolines; inhibit signal; transduction mediated
Prior art date: 2000-08-26

Application number

MYPI20013985A

Other languages

English (en)

Inventor

Frank Dr Himmelsbach

Elke Dr Langkopf

Birgit Dr Jung

Stefan Dr Blech

Flavia Dr Solca

Original Assignee

Boehringer Ingelheim Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-08-26

Filing date

2001-08-24

Publication date

2006-09-29

2001-08-24 Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma

2006-09-29 Publication of MY126132A publication Critical patent/MY126132A/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/94—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Immunology (AREA)
Oncology (AREA)
Urology & Nephrology (AREA)
Gastroenterology & Hepatology (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

MYPI20013985A 2000-08-26 2001-08-24 Aminoquinazolines which inhibit signal transduction mediated by tyrosine kinases MY126132A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE10042058A DE10042058A1 (de)	2000-08-26	2000-08-26	Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung

Publications (1)

Publication Number	Publication Date
MY126132A true MY126132A (en)	2006-09-29

Family

ID=7653945

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MYPI20013985A MY126132A (en)	2000-08-26	2001-08-24	Aminoquinazolines which inhibit signal transduction mediated by tyrosine kinases

Country Status (30)

Country	Link
EP (1)	EP1315705A1 (sr)
JP (1)	JP4834282B2 (sr)
KR (1)	KR100862873B1 (sr)
CN (1)	CN100404517C (sr)
AR (1)	AR033562A1 (sr)
AU (2)	AU2001287694B2 (sr)
BG (1)	BG107559A (sr)
BR (1)	BR0113519A (sr)
CA (1)	CA2417897C (sr)
CZ (1)	CZ302567B6 (sr)
DE (1)	DE10042058A1 (sr)
EA (1)	EA005679B1 (sr)
EC (1)	ECSP034464A (sr)
EE (1)	EE05269B1 (sr)
HR (1)	HRP20030138A2 (sr)
HU (1)	HUP0300819A3 (sr)
IL (2)	IL154602A0 (sr)
ME (1)	MEP58708A (sr)
MX (1)	MXPA03001483A (sr)
MY (1)	MY126132A (sr)
NO (1)	NO324866B1 (sr)
NZ (1)	NZ524668A (sr)
PL (1)	PL360248A1 (sr)
RS (1)	RS52279B (sr)
SK (1)	SK287747B6 (sr)
TW (1)	TWI294422B (sr)
UA (1)	UA73004C2 (sr)
UY (1)	UY26903A1 (sr)
WO (1)	WO2002018351A1 (sr)
ZA (1)	ZA200300991B (sr)

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CA2375259C (en)	1999-06-21	2009-04-28	Boehringer Ingelheim Pharma Kg	Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for preparing them
DE10042059A1 (de) *	2000-08-26	2002-03-07	Boehringer Ingelheim Pharma	Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung
US7019012B2 (en)	2000-12-20	2006-03-28	Boehringer Ingelheim International Pharma Gmbh & Co. Kg	Quinazoline derivatives and pharmaceutical compositions containing them
TW200813014A (en) *	2002-03-28	2008-03-16	Astrazeneca Ab	Quinazoline derivatives
KR101064530B1 (ko) *	2002-03-30	2011-09-14	베링거 잉겔하임 파르마 게엠베하 운트 코 카게	티로신 키나아제 억제제로서의 4-(ｎ-페닐아미노)-퀴나졸린/퀴놀린, 이를 함유하는 약제학적 조성물 및 이의 제조방법
US6924285B2 (en)	2002-03-30	2005-08-02	Boehringer Ingelheim Pharma Gmbh & Co.	Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them
DE10214412A1 (de) *	2002-03-30	2003-10-09	Boehringer Ingelheim Pharma	Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung
EP2280003B1 (en)	2002-07-15	2014-04-02	Symphony Evolution, Inc.	Process for preparing receptor-type kinase modulators
DE10326186A1 (de)	2003-06-06	2004-12-23	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung
DE10334226A1 (de) *	2003-07-28	2005-02-17	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Verwendung von Tyrosinkinase-Inhibitoren zur Behandlung inflammatorischer Prozesse
GB0317665D0 (en)	2003-07-29	2003-09-03	Astrazeneca Ab	Qinazoline derivatives
MXPA06002964A (es)	2003-09-16	2006-06-14	Astrazeneca Ab	Derivados de quinazolina como inhibidores de cinasa de tirosina.
US8318752B2 (en)	2003-09-19	2012-11-27	Astrazeneca Ab	4-(3-chloro-2-fluoroanilino)-7-methoxy-6-{[1-(N-methylcarbamoyl-methyl)piperidin-4-yl]oxy}quinazoline, its pharmaceutically acceptable salts, and pharmaceutical compositions comprising the same
EP2392565B1 (en)	2003-09-26	2014-03-19	Exelixis, Inc.	c-Met modulators and methods of use
DE10345875A1 (de) *	2003-09-30	2005-04-21	Boehringer Ingelheim Pharma	Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel, deren Vewendung und Verfahren zu ihrer Herstellung
US7456189B2 (en)	2003-09-30	2008-11-25	Boehringer Ingelheim International Gmbh	Bicyclic heterocycles, medicaments containing these compounds, their use and processes for their preparation
DE10350717A1 (de) *	2003-10-30	2005-06-02	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Verwendung von Tyrosinkinase-Inhibitoren zur Behandlung inflammatorischer Prozesse
US20060035893A1 (en)	2004-08-07	2006-02-16	Boehringer Ingelheim International Gmbh	Pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders
PE20060777A1 (es)	2004-12-24	2006-10-06	Boehringer Ingelheim Int	Derivados de indolinona para el tratamiento o la prevencion de enfermedades fibroticas
ATE521603T1 (de)	2005-02-26	2011-09-15	Astrazeneca Ab	Chinazolinderivate als tyrosinkinaseinhibitoren
KR100673775B1 (ko) *	2005-04-08	2007-01-24	엘지전자 주식회사	냉장고용 홈바
US20100234371A1 (en) *	2005-08-22	2010-09-16	Frank Himmelsbach	Bicyclic heterocycles, pharmaceutical compositions containing these compounds, the use thereof and processes for the preparation thereof
JP5688877B2 (ja)	2005-11-11	2015-03-25	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	癌疾患の治療用キナゾリン誘導体
WO2007101782A1 (de) *	2006-03-09	2007-09-13	Boehringer Ingelheim International Gmbh	Bicyclische heterocyclen, diese verbindungen enthaltende arzneimittel, deren verwendung und verfahren zu ihrer herstellung
DK2068880T3 (da)	2006-09-18	2012-07-23	Boehringer Ingelheim Int	Fremgangsmåde til behandling af cancer, der huser EGFR-mutationer
EP1921070A1 (de)	2006-11-10	2008-05-14	Boehringer Ingelheim Pharma GmbH & Co. KG	Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstelllung
EA200901041A1 (ru)	2007-02-06	2010-02-26	Бёрингер Ингельхайм Интернациональ Гмбх	Бициклические гетероциклы, содержащие эти соединения лекарственные средства, их применение и способ их получения
JP5336516B2 (ja)	2008-02-07	2013-11-06	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	スピロ環式複素環化合物、該化合物を含む医薬品、その使用及びその製造方法
BRPI0912170A2 (pt)	2008-05-13	2015-10-13	Astrazeneca Ab	composto, forma a, processo para a preparação da mesma, composição farmacêutica, uso de um composto, e, método para tratar um câncer em um animal de sangue quente
CA2733153C (en)	2008-08-08	2016-11-08	Boehringer Ingelheim International Gmbh	Cyclohexyloxy substituted heterocycles, pharmaceutical compositions containing these compounds and processes for preparing them
RS52754B2 (sr)	2009-01-16	2022-08-31	Exelixis Inc	Malat so n-(4- {[6,7-bis(metiloksi)hinolin-4-il]oksi}fenil-n'- (4-fluorofenil) ciklopropan-1,1-dikarboksamid-a, i njeni kristalni oblici za lečenje karcinoma
HUE044629T2 (hu)	2009-07-06	2019-11-28	Boehringer Ingelheim Int	Eljárás BIBW2992, annak sói, valamint e hatóanyagot tartalmazó szilárd gyógyászati készítmények szárítására
UA108618C2 (uk)	2009-08-07	2015-05-25		Застосування c-met-модуляторів в комбінації з темозоломідом та/або променевою терапією для лікування раку
KR101317809B1 (ko)	2011-06-07	2013-10-16	한미약품 주식회사	암세포의 성장을 억제하는 아마이드 유도체 및 비금속염 활택제를 포함하는 약학 조성물
KR20140096571A (ko)	2013-01-28	2014-08-06	한미약품 주식회사	1-(4-(4-(3,4-디클로로-2-플루오로페닐아미노)-7-메톡시퀴나졸린-6-일옥시)피페리딘-1-일)프로프-2-엔-1-온의 제조방법
DK2964638T3 (en)	2013-03-06	2017-10-30	Astrazeneca Ab	QUINAZOLIN INHIBITORS TO ACTIVATE MUTANEOUS FORMS OF EPIDERMAL GROWTH FACTOR RECEPTOR
US9242965B2 (en)	2013-12-31	2016-01-26	Boehringer Ingelheim International Gmbh	Process for the manufacture of (E)-4-N,N-dialkylamino crotonic acid in HX salt form and use thereof for synthesis of EGFR tyrosine kinase inhibitors
CA2943011A1 (en) *	2014-04-04	2015-10-08	H. Lundbeck A/S	Halogenated quinazolin-thf-amines as pde1 inhibitors
US20170176028A1 (en)	2015-12-18	2017-06-22	Lg Electronics Inc.	Air conditioner
US11446302B2 (en)	2016-11-17	2022-09-20	Board Of Regents, The University Of Texas System	Compounds with anti-tumor activity against cancer cells bearing EGFR or HER2 exon 20 mutations
CN112321814B (zh) *	2020-12-30	2021-03-23	广州初曲科技有限公司	一种吉非替尼艾地苯醌轭合物的制备及用途

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GB9624482D0 (en) *	1995-12-18	1997-01-15	Zeneca Phaema S A	Chemical compounds
JP4471404B2 (ja) *	1996-02-13	2010-06-02	アストラゼネカユーケイリミテッド	Ｖｅｇｆインヒビターとしてのキナゾリン誘導体
GB9603095D0 (en) *	1996-02-14	1996-04-10	Zeneca Ltd	Quinazoline derivatives
ATE211134T1 (de) *	1996-03-05	2002-01-15		4-anilinochinazolin derivate
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GB9718972D0 (en) *	1996-09-25	1997-11-12	Zeneca Ltd	Chemical compounds
DE19911509A1 (de) *	1999-03-15	2000-09-21	Boehringer Ingelheim Pharma	Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung

2000
- 2000-08-26 DE DE10042058A patent/DE10042058A1/de not_active Ceased
2001
- 2001-08-18 JP JP2002523469A patent/JP4834282B2/ja not_active Expired - Fee Related
- 2001-08-18 IL IL15460201A patent/IL154602A0/xx unknown
- 2001-08-18 PL PL36024801A patent/PL360248A1/xx not_active Application Discontinuation
- 2001-08-18 AU AU2001287694A patent/AU2001287694B2/en not_active Ceased
- 2001-08-18 EA EA200300219A patent/EA005679B1/ru not_active IP Right Cessation
- 2001-08-18 ME MEP-587/08A patent/MEP58708A/xx unknown
- 2001-08-18 AU AU8769401A patent/AU8769401A/xx active Pending
- 2001-08-18 HU HU0300819A patent/HUP0300819A3/hu unknown
- 2001-08-18 UA UA2003032533A patent/UA73004C2/uk unknown
- 2001-08-18 BR BR0113519-8A patent/BR0113519A/pt not_active Application Discontinuation
- 2001-08-18 EE EEP200300077A patent/EE05269B1/xx not_active IP Right Cessation
- 2001-08-18 MX MXPA03001483A patent/MXPA03001483A/es active IP Right Grant
- 2001-08-18 HR HR20030138A patent/HRP20030138A2/hr not_active Application Discontinuation
- 2001-08-18 CZ CZ20030870A patent/CZ302567B6/cs not_active IP Right Cessation
- 2001-08-18 NZ NZ524668A patent/NZ524668A/en not_active IP Right Cessation
- 2001-08-18 SK SK231-2003A patent/SK287747B6/sk not_active IP Right Cessation
- 2001-08-18 CA CA002417897A patent/CA2417897C/en not_active Expired - Fee Related
- 2001-08-18 EP EP01967285A patent/EP1315705A1/de not_active Ceased
- 2001-08-18 RS YU14003A patent/RS52279B/sr unknown
- 2001-08-18 KR KR1020037002744A patent/KR100862873B1/ko not_active Expired - Fee Related
- 2001-08-18 CN CNB01814635XA patent/CN100404517C/zh not_active Expired - Fee Related
- 2001-08-18 WO PCT/EP2001/009532 patent/WO2002018351A1/de not_active Ceased
- 2001-08-23 UY UY26903A patent/UY26903A1/es not_active Application Discontinuation
- 2001-08-24 AR ARP010104041A patent/AR033562A1/es unknown
- 2001-08-24 MY MYPI20013985A patent/MY126132A/en unknown
- 2001-08-24 TW TW090120905A patent/TWI294422B/zh not_active IP Right Cessation
2003
- 2003-02-03 EC EC2003004464A patent/ECSP034464A/es unknown
- 2003-02-05 ZA ZA200300991A patent/ZA200300991B/en unknown
- 2003-02-14 BG BG107559A patent/BG107559A/bg unknown
- 2003-02-24 IL IL154602A patent/IL154602A/en not_active IP Right Cessation
- 2003-02-25 NO NO20030870A patent/NO324866B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
IL154602A (en)	2008-07-08
HUP0300819A2 (hu)	2003-09-29
UY26903A1 (es)	2002-03-22
RS52279B (sr)	2012-10-31
CZ302567B6 (cs)	2011-07-13
ECSP034464A (es)	2003-03-31
AU8769401A (en)	2002-03-13
EA005679B1 (ru)	2005-04-28
BG107559A (bg)	2003-10-31
BR0113519A (pt)	2003-07-01
MEP58708A (en)	2011-05-10
TWI294422B (en)	2008-03-11
KR20030024914A (ko)	2003-03-26
HK1057557A1 (zh)	2004-04-08
SK287747B6 (sk)	2011-08-04
MXPA03001483A (es)	2003-06-06
AR033562A1 (es)	2003-12-26
EP1315705A1 (de)	2003-06-04
AU2001287694B2 (en)	2007-09-06
NZ524668A (en)	2006-06-30
ZA200300991B (en)	2004-04-16
CA2417897C (en)	2009-03-31
EE200300077A (et)	2004-12-15
IL154602A0 (en)	2003-09-17
HRP20030138A2 (en)	2005-04-30
UA73004C2 (uk)	2005-05-16
CN1449390A (zh)	2003-10-15
DE10042058A1 (de)	2002-03-07
WO2002018351A1 (de)	2002-03-07
NO20030870L (no)	2003-02-25
PL360248A1 (en)	2004-09-06
JP4834282B2 (ja)	2011-12-14
NO324866B1 (no)	2007-12-17
NO20030870D0 (no)	2003-02-25
HUP0300819A3 (en)	2008-03-28
JP2004507529A (ja)	2004-03-11
EA200300219A1 (ru)	2003-08-28
EE05269B1 (et)	2010-02-15
CN100404517C (zh)	2008-07-23
SK2312003A3 (en)	2003-10-07
CA2417897A1 (en)	2003-01-30
KR100862873B1 (ko)	2008-10-15
YU14003A (sh)	2006-01-16

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