MY8700184A - 6 7-benzomorphan derivatives processes for their production pharmaceutical compositions containing said derivatives and their use as pharmaceuticals - Google Patents

6 7-benzomorphan derivatives processes for their production pharmaceutical compositions containing said derivatives and their use as pharmaceuticals

Info

Publication number: MY8700184A
Authority: MY; Malaysia
Prior art keywords: derivatives; hydrogen; pharmaceuticals; pharmaceutical compositions; compositions containing
Prior art date: 1979-10-23

Application number

MY184/87A

Other languages

English (en)

Inventor

Anthony Marie Dr Akkerman

Hermanus C C K Van Dr Bakel

Roelof Christian Klaas Smit

Hendricus Bernardus Anto Welle

Magda Dr Marko

Original Assignee

Acf Chemiefarma Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-10-23

Filing date

1987-12-30

Publication date

1987-12-31

1987-12-30 Application filed by Acf Chemiefarma Nv filed Critical Acf Chemiefarma Nv

1987-12-31 Publication of MY8700184A publication Critical patent/MY8700184A/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/26—Benzomorphans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Hydrogenated Pyridines (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Pyrrole Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

MY184/87A 1979-10-23 1987-12-30 6 7-benzomorphan derivatives processes for their production pharmaceutical compositions containing said derivatives and their use as pharmaceuticals MY8700184A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
NL7907800A NL7907800A (nl)	1979-10-23	1979-10-23	Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan, farmaceutische preparaten die een dergelijke verbinding bevatten, alsmede werkwijze voor het bereiden van deze verbindingen en de farmaceutische preparaten.

Publications (1)

Publication Number	Publication Date
MY8700184A true MY8700184A (en)	1987-12-31

Family

ID=19834064

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MY184/87A MY8700184A (en)	1979-10-23	1987-12-30	6 7-benzomorphan derivatives processes for their production pharmaceutical compositions containing said derivatives and their use as pharmaceuticals

Country Status (17)

Country	Link
US (2)	US4406904A (fr)
EP (1)	EP0028717B1 (fr)
JP (1)	JPS5686164A (fr)
AT (1)	ATE8990T1 (fr)
AU (1)	AU539310B2 (fr)
CA (1)	CA1155840A (fr)
DE (1)	DE3068961D1 (fr)
DK (1)	DK435380A (fr)
ES (1)	ES496167A0 (fr)
FI (1)	FI67373C (fr)
IE (1)	IE50667B1 (fr)
IL (1)	IL61324A (fr)
MY (1)	MY8700184A (fr)
NL (1)	NL7907800A (fr)
NZ (1)	NZ195329A (fr)
PT (1)	PT71949B (fr)
ZA (1)	ZA806528B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4579950A (en) *	1982-08-20	1986-04-01	Hoechst-Roussel Pharmaceuticals Inc.	Intermediates for spiro[2H-1,4-benzodioxepin-3(5H)4'-piperidine] compounds
JPH01102077A (ja) *	1987-09-24	1989-04-19	Hoechst Roussel Pharmaceut Inc	２，６‐メタノピロロ‐３‐ベンズアゾジン類
DE4121821A1 (de) *	1991-07-02	1993-01-14	Boehringer Ingelheim Kg	Neue benzomorphane und ihre verwendung als arzneimittel
DE19528472A1 (de) *	1995-08-03	1997-02-06	Boehringer Ingelheim Kg	Neues Verfahren zur Herstellung von Norbenzomorphan einer Zwischenstufe bei Herstellung von pharmazeutisch wertvollen Benzomorphanderivaten, insbesondere von (-)-(1R,5S,S"R)-3'-Hydroxy-2-(2-methoxypropyl-)-5,9,9-trimethyl-6,7 benzomorphan
WO1999020223A2 (fr) *	1997-10-20	1999-04-29	Novo Nordisk A/S	Antagonistes de l'hormone luteinisante utiles pour le traitement de carences oestrogeniques ou utilises en tant que contraceptif
US6136980A (en) *	1998-05-01	2000-10-24	Boehringer Ingelheim Kg	Method of preparing norbenzomorphane as an intermediate in the preparation of pharmaceutically useful benzomorphane derivatives, in particular (-)-(1R,5S,2"R)-3'-hydroxy-2-(2-methoxypropyl)-5,9,9-trimethyl-6,7-benzo morphane
JP2003509478A (ja)	1999-09-21	2003-03-11	エモリー・ユニバーシティ	血小板関連障害を処置する方法および組成物
US6495694B2 (en) *	2000-06-16	2002-12-17	Boehringer Ingelheim Pharma Kg	Efficient separation of enantiomers of piperidone derivatives by precipitation of the desired eantiomer during in situ racemization of the unwanted enantiomer
WO2013167963A1 (fr)	2012-05-11	2013-11-14	Purdue Pharma L.P.	Composés de type benzomorphane utilisés en tant que modulateurs des récepteurs aux opiacés
US10138207B2 (en)	2012-11-09	2018-11-27	Purdue Pharma, L.P.	Benzomorphan analogs and the use thereof
EP2951160B1 (fr) *	2013-01-31	2019-04-24	Purdue Pharma LP	Analogues de benzomorphane et leur utilisation
CA2948144A1 (fr)	2014-05-06	2015-11-12	Purdue Pharma L.P.	Analogues du benzomorphane et leur utilisation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1050227A (fr)	1963-11-07
US4087532A (en)	1974-03-09	1978-05-02	Boehringer Ingelheim Gmbh	Analgesically useful 2-tetrahydrofurfuryl-5-lower alkyl-2-oxy-6,7-benzomorphans and salts thereof
GB1513961A (en) *	1975-02-25	1978-06-14	Acf Chemiefarma Nv	6,7-benzomorphans method for their preparation and intermediates
DE2716687A1 (de)	1977-04-15	1978-10-19	Boehringer Sohn Ingelheim	2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
US4202897A (en) *	1977-07-25	1980-05-13	Sandoz, Inc.	Prolactin secretion inhibitors
IT8049377A0 (it)	1979-08-03	1980-07-30	Sandoz Ag	Medicamento a base di composti triciclici per inibire la secrezione dell'ormone luteinizzante(caso 1005224)

1979
- 1979-10-23 NL NL7907800A patent/NL7907800A/nl not_active Application Discontinuation
1980
- 1980-10-13 EP EP80106213A patent/EP0028717B1/fr not_active Expired
- 1980-10-13 AT AT80106213T patent/ATE8990T1/de active
- 1980-10-13 DE DE8080106213T patent/DE3068961D1/de not_active Expired
- 1980-10-14 DK DK435380A patent/DK435380A/da not_active Application Discontinuation
- 1980-10-14 FI FI803237A patent/FI67373C/fi not_active IP Right Cessation
- 1980-10-21 AU AU63540/80A patent/AU539310B2/en not_active Ceased
- 1980-10-21 IL IL61324A patent/IL61324A/xx unknown
- 1980-10-21 CA CA000362879A patent/CA1155840A/fr not_active Expired
- 1980-10-21 NZ NZ195329A patent/NZ195329A/en unknown
- 1980-10-22 PT PT71949A patent/PT71949B/pt unknown
- 1980-10-22 JP JP14887180A patent/JPS5686164A/ja active Pending
- 1980-10-22 ES ES496167A patent/ES496167A0/es active Granted
- 1980-10-22 IE IE2188/80A patent/IE50667B1/en unknown
- 1980-10-23 ZA ZA00806528A patent/ZA806528B/xx unknown
1981
- 1981-07-13 US US06/283,084 patent/US4406904A/en not_active Expired - Fee Related
- 1981-07-13 US US06/282,799 patent/US4425353A/en not_active Expired - Fee Related
1987
- 1987-12-30 MY MY184/87A patent/MY8700184A/xx unknown

Also Published As

Publication number	Publication date
NL7907800A (nl)	1981-04-27
ZA806528B (en)	1982-06-30
DE3068961D1 (en)	1984-09-20
IE802188L (en)	1981-04-23
JPS5686164A (en)	1981-07-13
DK435380A (da)	1981-04-24
CA1155840A (fr)	1983-10-25
EP0028717A1 (fr)	1981-05-20
NZ195329A (en)	1984-05-31
FI67373C (fi)	1985-03-11
PT71949B (en)	1981-12-17
FI67373B (fi)	1984-11-30
US4425353A (en)	1984-01-10
AU6354080A (en)	1981-04-30
IE50667B1 (en)	1986-06-11
PT71949A (en)	1981-08-19
ES8106894A1 (es)	1981-09-16
EP0028717B1 (fr)	1984-08-15
IL61324A (en)	1985-03-31
ATE8990T1 (de)	1984-09-15
ES496167A0 (es)	1981-09-16
IL61324A0 (en)	1980-12-31
FI803237L (fi)	1981-04-24
AU539310B2 (en)	1984-09-20
US4406904A (en)	1983-09-27

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