NL7801454A - Imidazoolderivaten en hun overeenkomstige sulfoxiden en sulfonen met anti-ontstekings- werking. - Google Patents

Imidazoolderivaten en hun overeenkomstige sulfoxiden en sulfonen met anti-ontstekings- werking.

Info

Publication number: NL7801454A
Authority: NL; Netherlands
Prior art keywords: sulphones; imidazole derivatives; inflammatory action; corresponding sulfoxides; sulfoxides
Prior art date: 1977-02-09

Application number

NL7801454A

Other languages

English (en)

Dutch (nl)

Original Assignee

Du Pont

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-02-09

Filing date

1978-02-08

Publication date

1978-08-11

1978-02-08 Application filed by Du Pont filed Critical Du Pont

1978-08-11 Publication of NL7801454A publication Critical patent/NL7801454A/xx

Links

RAXXELZNTBOGNW-UHFFFAOYSA-N 1H-imidazole Chemical class C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 title 1
230000003110 anti-inflammatory effect Effects 0.000 title 1
229940079865 intestinal antiinfectives imidazole derivative Drugs 0.000 title 1
150000003462 sulfoxides Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pain & Pain Management (AREA)
Pharmacology & Pharmacy (AREA)
Rheumatology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

NL7801454A 1977-02-09 1978-02-08 Imidazoolderivaten en hun overeenkomstige sulfoxiden en sulfonen met anti-ontstekings- werking. NL7801454A (nl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US76721977A	1977-02-09	1977-02-09
US05/865,831 US4182769A (en)	1977-02-09	1978-01-05	Anti-inflammatory 1-substituted-4,5-diaryl-2-(substituted-thio) imidazoles and their corresponding sulfoxides and sulfones

Publications (1)

Publication Number	Publication Date
NL7801454A true NL7801454A (nl)	1978-08-11

Family

ID=27117878

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NL7801454A NL7801454A (nl)	1977-02-09	1978-02-08	Imidazoolderivaten en hun overeenkomstige sulfoxiden en sulfonen met anti-ontstekings- werking.

Country Status (27)

Country	Link
US (1)	US4182769A (it)
JP (1)	JPS53130665A (it)
AR (1)	AR221590A1 (it)
AT (1)	AT363076B (it)
AU (1)	AU524360B2 (it)
CA (1)	CA1107286A (it)
CH (1)	CH643834A5 (it)
DE (1)	DE2805166A1 (it)
DK (1)	DK16878A (it)
ES (1)	ES466793A1 (it)
FI (1)	FI68619C (it)
FR (1)	FR2380264A1 (it)
GB (1)	GB1587373A (it)
GR (1)	GR64157B (it)
HU (1)	HU181868B (it)
IE (1)	IE46454B1 (it)
IL (1)	IL53996A (it)
IT (1)	IT1092439B (it)
LU (1)	LU79028A1 (it)
MX (1)	MX5934E (it)
NL (1)	NL7801454A (it)
NO (1)	NO149813C (it)
NZ (1)	NZ186411A (it)
PT (1)	PT67625B (it)
SE (1)	SE7801466L (it)
SU (1)	SU867301A3 (it)
YU (1)	YU28978A (it)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2823197A1 (de) *	1978-05-24	1979-11-29	Schering Ag	Neue imidazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE2966706D1 (en) *	1978-08-10	1984-03-29	Ciba Geigy Ag	Substituted anthranilic acid amides, process for their preparation, pharmaceutical compositions containing them and their preparation
US4308277A (en) *	1978-08-10	1981-12-29	Ciba-Geigy Corporation	2,4,5-Trisubstituted imidazolines and pharmaceutical compositions containing same
US4199592A (en) *	1978-08-29	1980-04-22	E. I. Du Pont De Nemours And Company	Antiinflammatory 4,5-diaryl-2-nitroimidazoles
DK337779A (da) *	1978-10-02	1980-04-03	Du Pont	Fremgangsmaade til fremstilling af antiinflammatoriske 2-substituerede 1h-phenantro (9,10)-imidazoler
DE2856909A1 (de) *	1978-12-28	1980-07-17	Schering Ag	Neue imidazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
IT1110282B (it) *	1979-02-19	1985-12-23	Acraf	Tio-indazoli basici
DE3025484A1 (de) *	1980-07-03	1982-02-04	Schering Ag, 1000 Berlin Und 4619 Bergkamen	Neue imidazol-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
US4438117A (en)	1980-09-03	1984-03-20	E. I. Du Pont De Nemours And Company	2-Substituted thio-4,5-diarylpyrimidines
US4355041A (en) *	1982-01-04	1982-10-19	E. I. Du Pont De Nemours And Company	4,5-Bis-(4-fluorophenyl)-1-(4-nitrobenzyl)-2-[((1,1,2,2-tetrafluoroethyl)sulfonyl]-1H-imidazole, composition and use
US4503065A (en) *	1982-08-03	1985-03-05	E. I. Du Pont De Nemours And Company	Antiinflammatory 4,5-diaryl 1-2-halo imidazoles
ZA826501B (en) *	1982-09-06	1984-04-25	Du Pont	Anti-hypertensive imidazole derivative
DE3504678A1 (de) *	1985-02-12	1986-08-14	A. Nattermann & Cie GmbH, 5000 Köln	Neue imidazolyl-oxyalkansaeuren und -thioalkansaeuren, ihre derivate und verfahren zu ihrer herstellung
DE3508665A1 (de) *	1985-03-12	1986-09-18	Hoechst Ag, 6230 Frankfurt	Heterocyclische sulfide und ihre anwendung als immunmodulatoren
US4686231A (en) *	1985-12-12	1987-08-11	Smithkline Beckman Corporation	Inhibition of 5-lipoxygenase products
US4780470A (en) *	1986-08-19	1988-10-25	Smithkline Beckman Corporation	Inhibition of interleukin-1 by monocytes and/or macrophages
US5300519A (en) *	1988-07-06	1994-04-05	The University Of Sheffield	Immunosuppressive agents
US5098707A (en) *	1989-07-31	1992-03-24	Merck & Co., Inc.	Imidazole compounds and their use as transglutaminase inhibitors
US5030644A (en) *	1989-07-31	1991-07-09	Merck & Co., Inc.	Imidazole compounds and their use as transglutaminase inhibitors
JPH03145473A (ja) *	1989-10-27	1991-06-20	Hisamitsu Pharmaceut Co Inc	新規なイミダゾール酢酸誘導体
GB9005966D0 (en) *	1990-03-16	1990-05-09	May & Baker Ltd	New compositions of matter
DE4010797A1 (de) *	1990-04-04	1991-10-10	Hoechst Ag	Substituierte azole, verfahren zu deren herstellung, diese enthaltende mittel und deren verwendung
US6040320A (en) *	1997-06-30	2000-03-21	Ortho-Mcneil Pharmaceutical, Inc.	2-substituted imidazoles useful in the treatment of inflammatory diseases
FR2823747B1 (fr) *	2001-04-24	2003-05-23	Oreal	Nouveaux composes de la famille des 3-alkyl-(4,5 diphenyl- imidazol-1-yl) et leur utilisation comme anti-inflammatoires
WO2016010611A1 (en)	2014-07-18	2016-01-21	Ohio University	Methods and compositions to modify gsk-3 activity

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1155580A (en) *	1965-10-21	1969-06-18	Geigy Ag J R	New Imidazole Derivatives their Production and Use
US3707475A (en) *	1970-11-16	1972-12-26	Pfizer	Antiinflammatory imidazoles
US3929807A (en) *	1971-05-10	1975-12-30	Ciba Geigy Corp	2-Substituted-4(5)-(aryl)-5(4)-(2,3 or -4-pyridyl)-imidazoles
JPS5343958B2 (it) *	1972-07-29	1978-11-24

1978
- 1978-01-05 US US05/865,831 patent/US4182769A/en not_active Expired - Lifetime
- 1978-01-13 DK DK16878A patent/DK16878A/da not_active Application Discontinuation
- 1978-02-06 PT PT67625A patent/PT67625B/pt unknown
- 1978-02-07 CA CA296,605A patent/CA1107286A/en not_active Expired
- 1978-02-07 IT IT20079/78A patent/IT1092439B/it active
- 1978-02-08 LU LU79028A patent/LU79028A1/xx unknown
- 1978-02-08 AT AT0087078A patent/AT363076B/de not_active IP Right Cessation
- 1978-02-08 AU AU33097/78A patent/AU524360B2/en not_active Expired
- 1978-02-08 IL IL53996A patent/IL53996A/xx unknown
- 1978-02-08 GB GB5097/78A patent/GB1587373A/en not_active Expired
- 1978-02-08 FR FR7803517A patent/FR2380264A1/fr not_active Withdrawn
- 1978-02-08 IE IE280/78A patent/IE46454B1/en unknown
- 1978-02-08 YU YU00289/78A patent/YU28978A/xx unknown
- 1978-02-08 NL NL7801454A patent/NL7801454A/xx not_active Application Discontinuation
- 1978-02-08 NO NO780432A patent/NO149813C/no unknown
- 1978-02-08 NZ NZ186411A patent/NZ186411A/xx unknown
- 1978-02-08 SU SU782574555A patent/SU867301A3/ru active
- 1978-02-08 SE SE7801466A patent/SE7801466L/xx unknown
- 1978-02-08 DE DE19782805166 patent/DE2805166A1/de not_active Withdrawn
- 1978-02-08 MX MX786830U patent/MX5934E/es unknown
- 1978-02-08 ES ES466793A patent/ES466793A1/es not_active Expired
- 1978-02-09 CH CH147578A patent/CH643834A5/de not_active IP Right Cessation
- 1978-02-09 AR AR271047A patent/AR221590A1/es active
- 1978-02-09 GR GR55397A patent/GR64157B/el unknown
- 1978-02-09 HU HU78DU280A patent/HU181868B/hu unknown
- 1978-02-09 JP JP1304778A patent/JPS53130665A/ja active Pending
- 1978-02-09 FI FI780429A patent/FI68619C/fi not_active IP Right Cessation

Also Published As

Publication number	Publication date
NO780432L (no)	1978-08-10
IL53996A (en)	1982-04-30
IE46454B1 (en)	1983-06-15
SU867301A3 (ru)	1981-09-23
GB1587373A (en)	1981-04-01
IT1092439B (it)	1985-07-12
IE780280L (en)	1978-08-09
FI68619C (fi)	1985-10-10
AU3309778A (en)	1979-08-16
GR64157B (en)	1980-02-05
CA1107286A (en)	1981-08-18
ATA87078A (de)	1980-12-15
PT67625B (en)	1979-07-17
DE2805166A1 (de)	1978-08-10
DK16878A (da)	1978-08-10
NO149813B (no)	1984-03-19
NZ186411A (en)	1981-03-16
AU524360B2 (en)	1982-09-16
FI780429A7 (fi)	1978-08-10
SE7801466L (sv)	1978-08-10
NO149813C (no)	1984-06-27
FR2380264A1 (fr)	1978-09-08
AT363076B (de)	1981-07-10
MX5934E (es)	1984-08-30
ES466793A1 (es)	1979-08-01
IL53996A0 (en)	1978-04-30
CH643834A5 (de)	1984-06-29
JPS53130665A (en)	1978-11-14
FI68619B (fi)	1985-06-28
IT7820079A0 (it)	1978-02-07
US4182769A (en)	1980-01-08
AR221590A1 (es)	1981-02-27
YU28978A (en)	1983-01-21
PT67625A (en)	1978-03-01
LU79028A1 (fr)	1979-05-25
HU181868B (en)	1983-11-28

Legal Events

Date	Code	Title
1984-12-03	BA	A request for search or an international-type search has been filed
1985-01-01	A85	Still pending on 85-01-01
1986-03-03	BB	A search report has been drawn up
1986-09-01	BV	The patent application has lapsed

Publication	Publication Date	Title
NL7805346A (nl)	1978-11-21	Hydroxyalfenonen en hun toepassing als fotosensibilisa- toren.
NL171017C (nl)	1983-02-01	Verbinding van implantaatmaterialen met verschillende eigenschappen.
NL191789C (nl)	1996-08-02	Acetylaminoalkaansulfonzuurderivaten met farmacologische eigenschappen.
NL7803644A (nl)	1978-10-09	Cyclo-alkaan-gesubstitueerde fenylazijnzuurverbindin- gen hun gebruik en bereiding.
BR7704597A (pt)	1978-03-28	Cateter de permanencia
IT7820079A0 (it)	1978-02-07	Immidazoli antinfiammatori e solfossidi e solfoni corrispondenti a essi.
IT7919369A0 (it)	1979-01-17	Derivati della tienoidantoina ad azione terapeutica.
FI783055A7 (fi)	1979-04-08	Anordning foer formande av vaogor i haor
NL173727C (nl)	1984-03-01	Stuurschroefconstructie met ophaalbare schroef.
FI773958A7 (fi)	1978-07-08	Anordning foer montering av propellerroder i farkost
ZA78769B (en)	1979-01-31	Anti-inflammatory imidazoles and their corresponding sulfoxides and sulfones
FI773306A7 (fi)	1978-05-13	Foerfarande foer aostadkommande av en enhetlig bild i bilddisplayanordningar
NO781224L (no)	1978-10-10	Busskarosseri.
IT7922720A0 (it)	1979-05-16	Derivati 4-ammino-2-piperidinochinazolinici ad azione terapeutica.
ATA208779A (de)	1983-08-15	Waermeisolierender profilkoerper
NL7801453A (nl)	1978-08-11	Imidazoolderivaten met een anti-ontstekings- werking en hun overeenkomstige sulfoxiden en sulfonen.
NL7808011A (nl)	1979-01-30	Norbornaan- en norborneen-derivaten.
NL7803725A (nl)	1978-10-13	4-alkylthio-2-trifluormethylalkaansulfonaniliden en derivaten daarvan.
BE844503R (fr)	1977-01-24	Sulfoxydes
FI782042A7 (fi)	1978-12-29	Anordning foer infoerande av gaser i vaetskor speciellt foer luftning av avfallsvatten
AT354135B (de)	1979-12-27	Doppelfernrohr
FI783908A7 (fi)	1979-06-23	Anordning foer reglering av daempkraften i en stoetdaempare
SE7805978L (sv)	1979-01-06	Kontinuerligt forrad av festorgan
NL7804189A (nl)	1978-10-24	Gesubstitueerde n-fenylformamidoximen en hun bereiding.
FI781711A7 (fi)	1978-12-04	Matarskiva i skivkvarn