NL8201763A - Werkwijze ter bereiding van fructose uit insuline. - Google Patents

Werkwijze ter bereiding van fructose uit insuline. Download PDF

Info

Publication number: NL8201763A
Authority: NL; Netherlands
Prior art keywords: inulinase; inulin; fructose; exo; endo
Prior art date: 1981-04-29

Application number

NL8201763A

Other languages

English (en)

Dutch (nl)

Original Assignee

Novo Industri As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-04-29

Filing date

1982-04-28

Publication date

1982-11-16

1982-04-28 Application filed by Novo Industri As filed Critical Novo Industri As

1982-11-16 Publication of NL8201763A publication Critical patent/NL8201763A/nl

Links

RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 title description 57
229930091371 Fructose Natural products 0.000 title description 57
239000005715 Fructose Substances 0.000 title description 57
238000004519 manufacturing process Methods 0.000 title description 7
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title 2
102000004877 Insulin Human genes 0.000 title 1
108090001061 Insulin Proteins 0.000 title 1
229940125396 insulin Drugs 0.000 title 1
229920001202 Inulin Polymers 0.000 claims description 63
JYJIGFIDKWBXDU-MNNPPOADSA-N inulin Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)OC[C@]1(OC[C@]2(OC[C@]3(OC[C@]4(OC[C@]5(OC[C@]6(OC[C@]7(OC[C@]8(OC[C@]9(OC[C@]%10(OC[C@]%11(OC[C@]%12(OC[C@]%13(OC[C@]%14(OC[C@]%15(OC[C@]%16(OC[C@]%17(OC[C@]%18(OC[C@]%19(OC[C@]%20(OC[C@]%21(OC[C@]%22(OC[C@]%23(OC[C@]%24(OC[C@]%25(OC[C@]%26(OC[C@]%27(OC[C@]%28(OC[C@]%29(OC[C@]%30(OC[C@]%31(OC[C@]%32(OC[C@]%33(OC[C@]%34(OC[C@]%35(OC[C@]%36(O[C@@H]%37[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O%37)O)[C@H]([C@H](O)[C@@H](CO)O%36)O)[C@H]([C@H](O)[C@@H](CO)O%35)O)[C@H]([C@H](O)[C@@H](CO)O%34)O)[C@H]([C@H](O)[C@@H](CO)O%33)O)[C@H]([C@H](O)[C@@H](CO)O%32)O)[C@H]([C@H](O)[C@@H](CO)O%31)O)[C@H]([C@H](O)[C@@H](CO)O%30)O)[C@H]([C@H](O)[C@@H](CO)O%29)O)[C@H]([C@H](O)[C@@H](CO)O%28)O)[C@H]([C@H](O)[C@@H](CO)O%27)O)[C@H]([C@H](O)[C@@H](CO)O%26)O)[C@H]([C@H](O)[C@@H](CO)O%25)O)[C@H]([C@H](O)[C@@H](CO)O%24)O)[C@H]([C@H](O)[C@@H](CO)O%23)O)[C@H]([C@H](O)[C@@H](CO)O%22)O)[C@H]([C@H](O)[C@@H](CO)O%21)O)[C@H]([C@H](O)[C@@H](CO)O%20)O)[C@H]([C@H](O)[C@@H](CO)O%19)O)[C@H]([C@H](O)[C@@H](CO)O%18)O)[C@H]([C@H](O)[C@@H](CO)O%17)O)[C@H]([C@H](O)[C@@H](CO)O%16)O)[C@H]([C@H](O)[C@@H](CO)O%15)O)[C@H]([C@H](O)[C@@H](CO)O%14)O)[C@H]([C@H](O)[C@@H](CO)O%13)O)[C@H]([C@H](O)[C@@H](CO)O%12)O)[C@H]([C@H](O)[C@@H](CO)O%11)O)[C@H]([C@H](O)[C@@H](CO)O%10)O)[C@H]([C@H](O)[C@@H](CO)O9)O)[C@H]([C@H](O)[C@@H](CO)O8)O)[C@H]([C@H](O)[C@@H](CO)O7)O)[C@H]([C@H](O)[C@@H](CO)O6)O)[C@H]([C@H](O)[C@@H](CO)O5)O)[C@H]([C@H](O)[C@@H](CO)O4)O)[C@H]([C@H](O)[C@@H](CO)O3)O)[C@H]([C@H](O)[C@@H](CO)O2)O)[C@@H](O)[C@H](O)[C@@H](CO)O1 JYJIGFIDKWBXDU-MNNPPOADSA-N 0.000 claims description 63
229940029339 inulin Drugs 0.000 claims description 63
108010090785 inulinase Proteins 0.000 claims description 47
230000000694 effects Effects 0.000 claims description 29
238000002360 preparation method Methods 0.000 claims description 29
238000000034 method Methods 0.000 claims description 28
238000006460 hydrolysis reaction Methods 0.000 claims description 20
230000007062 hydrolysis Effects 0.000 claims description 19
230000000813 microbial effect Effects 0.000 claims description 13
241000228195 Aspergillus ficuum Species 0.000 claims description 11
230000003301 hydrolyzing effect Effects 0.000 claims description 6
239000000203 mixture Substances 0.000 claims description 6
229910052799 carbon Inorganic materials 0.000 claims description 3
239000012736 aqueous medium Substances 0.000 claims description 2
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 45
239000008103 glucose Substances 0.000 description 45
229940088598 enzyme Drugs 0.000 description 41
101100256850 Drosophila melanogaster EndoA gene Proteins 0.000 description 40
108090000790 Enzymes Proteins 0.000 description 36
102000004190 Enzymes Human genes 0.000 description 36
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 21
239000000243 solution Substances 0.000 description 19
229930006000 Sucrose Natural products 0.000 description 12
CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 12
239000005720 sucrose Substances 0.000 description 12
239000000758 substrate Substances 0.000 description 11
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 10
239000000284 extract Substances 0.000 description 10
108090000623 proteins and genes Proteins 0.000 description 9
102000004169 proteins and genes Human genes 0.000 description 9
229920000642 polymer Polymers 0.000 description 8
241000196324 Embryophyta Species 0.000 description 7
WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 6
150000001720 carbohydrates Chemical class 0.000 description 6
244000005700 microbiome Species 0.000 description 6
239000006188 syrup Substances 0.000 description 6
235000020357 syrup Nutrition 0.000 description 6
NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 description 5
229920001817 Agar Polymers 0.000 description 5
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 5
239000008272 agar Substances 0.000 description 5
238000004458 analytical method Methods 0.000 description 5
238000009835 boiling Methods 0.000 description 5
238000001816 cooling Methods 0.000 description 5
239000003456 ion exchange resin Substances 0.000 description 5
229920003303 ion-exchange polymer Polymers 0.000 description 5
229910052757 nitrogen Inorganic materials 0.000 description 5
238000000926 separation method Methods 0.000 description 5
244000115658 Dahlia pinnata Species 0.000 description 4
235000012040 Dahlia pinnata Nutrition 0.000 description 4
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
230000015572 biosynthetic process Effects 0.000 description 4
239000006227 byproduct Substances 0.000 description 4
239000003795 chemical substances by application Substances 0.000 description 4
238000000760 immunoelectrophoresis Methods 0.000 description 4
239000000047 product Substances 0.000 description 4
244000285963 Kluyveromyces fragilis Species 0.000 description 3
235000014663 Kluyveromyces fragilis Nutrition 0.000 description 3
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
239000008351 acetate buffer Substances 0.000 description 3
238000005903 acid hydrolysis reaction Methods 0.000 description 3
108010051210 beta-Fructofuranosidase Proteins 0.000 description 3
239000000872 buffer Substances 0.000 description 3
230000002255 enzymatic effect Effects 0.000 description 3
238000001914 filtration Methods 0.000 description 3
239000012847 fine chemical Substances 0.000 description 3
238000004128 high performance liquid chromatography Methods 0.000 description 3
239000001573 invertase Substances 0.000 description 3
235000011073 invertase Nutrition 0.000 description 3
238000005342 ion exchange Methods 0.000 description 3
238000006317 isomerization reaction Methods 0.000 description 3
239000000463 material Substances 0.000 description 3
150000003839 salts Chemical class 0.000 description 3
235000000346 sugar Nutrition 0.000 description 3
241000228212 Aspergillus Species 0.000 description 2
241000228245 Aspergillus niger Species 0.000 description 2
244000298479 Cichorium intybus Species 0.000 description 2
235000007542 Cichorium intybus Nutrition 0.000 description 2
238000003556 assay Methods 0.000 description 2
-1 cationic ion Chemical class 0.000 description 2
238000006243 chemical reaction Methods 0.000 description 2
239000003153 chemical reaction reagent Substances 0.000 description 2
238000013375 chromatographic separation Methods 0.000 description 2
239000003245 coal Substances 0.000 description 2
238000012258 culturing Methods 0.000 description 2
238000002474 experimental method Methods 0.000 description 2
235000021433 fructose syrup Nutrition 0.000 description 2
235000011389 fruit/vegetable juice Nutrition 0.000 description 2
238000002523 gelfiltration Methods 0.000 description 2
125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 description 2
238000011534 incubation Methods 0.000 description 2
208000015181 infectious disease Diseases 0.000 description 2
239000002054 inoculum Substances 0.000 description 2
238000004255 ion exchange chromatography Methods 0.000 description 2
150000002500 ions Chemical class 0.000 description 2
238000006116 polymerization reaction Methods 0.000 description 2
239000003755 preservative agent Substances 0.000 description 2
238000000746 purification Methods 0.000 description 2
239000011780 sodium chloride Substances 0.000 description 2
239000007787 solid Substances 0.000 description 2
238000003860 storage Methods 0.000 description 2
239000000725 suspension Substances 0.000 description 2
UHPMCKVQTMMPCG-UHFFFAOYSA-N 5,8-dihydroxy-2-methoxy-6-methyl-7-(2-oxopropyl)naphthalene-1,4-dione Chemical compound CC1=C(CC(C)=O)C(O)=C2C(=O)C(OC)=CC(=O)C2=C1O UHPMCKVQTMMPCG-UHFFFAOYSA-N 0.000 description 1
GMVPRGQOIOIIMI-DODZYUBVSA-N 7-[(1R,2R,3R)-3-hydroxy-2-[(3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoic acid Chemical compound CCCCC[C@H](O)C=C[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O GMVPRGQOIOIIMI-DODZYUBVSA-N 0.000 description 1
241000208838 Asteraceae Species 0.000 description 1
241000219310 Beta vulgaris subsp. vulgaris Species 0.000 description 1
241000222120 Candida <Saccharomycetales> Species 0.000 description 1
235000008733 Citrus aurantifolia Nutrition 0.000 description 1
229920002271 DEAE-Sepharose Polymers 0.000 description 1
229920001353 Dextrin Polymers 0.000 description 1
239000004375 Dextrin Substances 0.000 description 1
241000233866 Fungi Species 0.000 description 1
241000223218 Fusarium Species 0.000 description 1
240000008892 Helianthus tuberosus Species 0.000 description 1
235000003230 Helianthus tuberosus Nutrition 0.000 description 1
241000283973 Oryctolagus cuniculus Species 0.000 description 1
241001364096 Pachycephalidae Species 0.000 description 1
241000228143 Penicillium Species 0.000 description 1
240000004808 Saccharomyces cerevisiae Species 0.000 description 1
229920002684 Sepharose Polymers 0.000 description 1
229920002472 Starch Polymers 0.000 description 1
235000021536 Sugar beet Nutrition 0.000 description 1
240000001949 Taraxacum officinale Species 0.000 description 1
235000005187 Taraxacum officinale ssp. officinale Nutrition 0.000 description 1
235000011941 Tilia x europaea Nutrition 0.000 description 1
239000002253 acid Substances 0.000 description 1
230000002378 acidificating effect Effects 0.000 description 1
239000008186 active pharmaceutical agent Substances 0.000 description 1
238000005377 adsorption chromatography Methods 0.000 description 1
239000011543 agarose gel Substances 0.000 description 1
LFVGISIMTYGQHF-UHFFFAOYSA-N ammonium dihydrogen phosphate Chemical compound [NH4+].OP(O)([O-])=O LFVGISIMTYGQHF-UHFFFAOYSA-N 0.000 description 1
229910000019 calcium carbonate Inorganic materials 0.000 description 1
229940041514 candida albicans extract Drugs 0.000 description 1
238000012512 characterization method Methods 0.000 description 1
239000003610 charcoal Substances 0.000 description 1
150000001875 compounds Chemical class 0.000 description 1
235000009508 confectionery Nutrition 0.000 description 1
238000011109 contamination Methods 0.000 description 1
238000004132 cross linking Methods 0.000 description 1
238000002425 crystallisation Methods 0.000 description 1
230000008025 crystallization Effects 0.000 description 1
235000019425 dextrin Nutrition 0.000 description 1
125000006159 dianhydride group Chemical group 0.000 description 1
238000009792 diffusion process Methods 0.000 description 1
229940079919 digestives enzyme preparation Drugs 0.000 description 1
238000010790 dilution Methods 0.000 description 1
239000012895 dilution Substances 0.000 description 1
ZPWVASYFFYYZEW-UHFFFAOYSA-L dipotassium hydrogen phosphate Chemical compound [K+].[K+].OP([O-])([O-])=O ZPWVASYFFYYZEW-UHFFFAOYSA-L 0.000 description 1
229910000396 dipotassium phosphate Inorganic materials 0.000 description 1
235000019797 dipotassium phosphate Nutrition 0.000 description 1
230000009977 dual effect Effects 0.000 description 1
235000013399 edible fruits Nutrition 0.000 description 1
230000007071 enzymatic hydrolysis Effects 0.000 description 1
238000006047 enzymatic hydrolysis reaction Methods 0.000 description 1
239000000706 filtrate Substances 0.000 description 1
235000013305 food Nutrition 0.000 description 1
238000005194 fractionation Methods 0.000 description 1
BJHIKXHVCXFQLS-UYFOZJQFSA-N fructose group Chemical group OCC(=O)[C@@H](O)[C@H](O)[C@H](O)CO BJHIKXHVCXFQLS-UYFOZJQFSA-N 0.000 description 1
239000000499 gel Substances 0.000 description 1
238000005227 gel permeation chromatography Methods 0.000 description 1
229940084947 glutose Drugs 0.000 description 1
150000004676 glycans Chemical class 0.000 description 1
238000003306 harvesting Methods 0.000 description 1
235000012907 honey Nutrition 0.000 description 1
229910052588 hydroxylapatite Inorganic materials 0.000 description 1
238000002649 immunization Methods 0.000 description 1
230000003053 immunization Effects 0.000 description 1
239000012535 impurity Substances 0.000 description 1
238000011081 inoculation Methods 0.000 description 1
239000004571 lime Substances 0.000 description 1
239000007788 liquid Substances 0.000 description 1
230000014759 maintenance of location Effects 0.000 description 1
238000002156 mixing Methods 0.000 description 1
150000002772 monosaccharides Chemical class 0.000 description 1
235000019520 non-alcoholic beverage Nutrition 0.000 description 1
235000008935 nutritious Nutrition 0.000 description 1
XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 1
239000008363 phosphate buffer Substances 0.000 description 1
229920001983 poloxamer Polymers 0.000 description 1
235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
229920001282 polysaccharide Polymers 0.000 description 1
239000005017 polysaccharide Substances 0.000 description 1
229920000053 polysorbate 80 Polymers 0.000 description 1
239000002244 precipitate Substances 0.000 description 1
238000001556 precipitation Methods 0.000 description 1
230000035484 reaction time Effects 0.000 description 1
230000000717 retained effect Effects 0.000 description 1
238000011218 seed culture Methods 0.000 description 1
239000008107 starch Substances 0.000 description 1
235000019698 starch Nutrition 0.000 description 1
239000008223 sterile water Substances 0.000 description 1
150000008163 sugars Chemical class 0.000 description 1
239000012138 yeast extract Substances 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01007—Inulinase (3.2.1.7)
- C—CHEMISTRY; METALLURGY
- C13—SUGAR INDUSTRY
- C13K—SACCHARIDES OBTAINED FROM NATURAL SOURCES OR BY HYDROLYSIS OF NATURALLY OCCURRING DISACCHARIDES, OLIGOSACCHARIDES OR POLYSACCHARIDES
- C13K11/00—Fructose

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Wood Science & Technology (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
General Health & Medical Sciences (AREA)
General Engineering & Computer Science (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

NL8201763A 1981-04-29 1982-04-28 Werkwijze ter bereiding van fructose uit insuline. NL8201763A (nl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DK189181		1981-04-29
DK189181A DK147409C (da)	1981-04-29	1981-04-29	Fremgangsmaade til hydrolysering af inulin ved hjaelp af et aspergillus ficuum-inulinasepraeparat

Publications (1)

Publication Number	Publication Date
NL8201763A true NL8201763A (nl)	1982-11-16

Family

ID=8108848

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NL8201763A NL8201763A (nl)	1981-04-29	1982-04-28	Werkwijze ter bereiding van fructose uit insuline.

Country Status (7)

Country	Link
JP (1)	JPS589695A (da)
BE (1)	BE893013A (da)
CA (1)	CA1184519A (da)
DK (1)	DK147409C (da)
FR (1)	FR2504939A1 (da)
NL (1)	NL8201763A (da)
YU (1)	YU42763B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3508387C1 (de) *	1985-03-08	1986-07-17	Günter Prof. Dr.-Ing. 1000 Berlin Bärwald	Verfahren zur Herstellung eines glukosearmen Aufschlussproduktes aus inulinhaltigen Pflanzenteilen
JPS62208277A (ja) *	1986-03-07	1987-09-12	Meiji Seika Kaisha Ltd	イヌリナ−ゼの製造法
EP0429077A3 (en) *	1989-11-24	1991-11-13	Mitsui Toatsu Chemicals, Incorporated	Process for producing inulooligosaccharides
BE1010450A3 (nl) *	1996-08-01	1998-08-04	Tiense Suikerraffinaderij Nv	Werkwijze voor het maken van een fructosestroop rijk aan fructose.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL7811389A (nl) *	1978-11-18	1980-05-20	Stamicarbon	Bereiding van fructose.
NL8003723A (nl) *	1980-06-27	1982-01-18	Stamicarbon	Inulinase.

1981
- 1981-04-29 DK DK189181A patent/DK147409C/da not_active IP Right Cessation
1982
- 1982-04-26 YU YU896/82A patent/YU42763B/xx unknown
- 1982-04-28 CA CA000401901A patent/CA1184519A/en not_active Expired
- 1982-04-28 FR FR8207341A patent/FR2504939A1/fr active Granted
- 1982-04-28 JP JP57072477A patent/JPS589695A/ja active Pending
- 1982-04-28 BE BE6/47647A patent/BE893013A/fr not_active IP Right Cessation
- 1982-04-28 NL NL8201763A patent/NL8201763A/nl not_active Application Discontinuation

Also Published As

Publication number	Publication date
YU89682A (en)	1984-10-31
DK189181A (da)	1982-10-30
CA1184519A (en)	1985-03-26
FR2504939B1 (da)	1985-03-01
BE893013A (fr)	1982-10-28
YU42763B (en)	1988-12-31
FR2504939A1 (fr)	1982-11-05
JPS589695A (ja)	1983-01-20
DK147409B (da)	1984-07-23
DK147409C (da)	1985-03-11

Legal Events

Date	Code	Title
1983-02-01	BT	A document has been added to the application laid open to public inspection
1985-01-01	A85	Still pending on 85-01-01
1989-01-02	BA	A request for search or an international-type search has been filed
1989-02-01	BB	A search report has been drawn up
1989-08-01	BV	The patent application has lapsed

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