NL8801651A - Cosmetische samenstelling met verdunnende werking en werking tegen cellulitis, waarvan het werkzame bestanddeel een 1-hydroxyalkylxanthine is. - Google Patents

Cosmetische samenstelling met verdunnende werking en werking tegen cellulitis, waarvan het werkzame bestanddeel een 1-hydroxyalkylxanthine is. Download PDF

Info

Publication number: NL8801651A
Authority: NL; Netherlands
Prior art keywords: hydroxybutyl; methylxanthine; hydroxypropyl; composition according; propyl
Prior art date: 1987-06-30

Application number

NL8801651A

Other languages

English (en)

Dutch (nl)

Original Assignee

Oreal

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-06-30

Filing date

1988-06-29

Publication date

1989-01-16

1988-06-29 Application filed by Oreal filed Critical Oreal

1989-01-16 Publication of NL8801651A publication Critical patent/NL8801651A/nl

Links

239000000203 mixture Substances 0.000 title claims description 33
239000013543 active substance Substances 0.000 title claims description 7
239000002537 cosmetic Substances 0.000 title claims description 6
230000009471 action Effects 0.000 title description 5
206010007882 Cellulitis Diseases 0.000 title 1
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 34
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 25
150000001875 compounds Chemical class 0.000 claims description 23
LRFVTYWOQMYALW-UHFFFAOYSA-N 9H-xanthine Chemical compound O=C1NC(=O)NC2=C1NC=N2 LRFVTYWOQMYALW-UHFFFAOYSA-N 0.000 claims description 11
208000035484 Cellulite Diseases 0.000 claims description 11
206010049752 Peau d'orange Diseases 0.000 claims description 11
239000002904 solvent Substances 0.000 claims description 10
125000004432 carbon atom Chemical group C* 0.000 claims description 8
230000000694 effects Effects 0.000 claims description 6
239000003921 oil Substances 0.000 claims description 6
235000014113 dietary fatty acids Nutrition 0.000 claims description 5
239000000839 emulsion Substances 0.000 claims description 5
239000000194 fatty acid Substances 0.000 claims description 5
229930195729 fatty acid Natural products 0.000 claims description 5
150000004665 fatty acids Chemical class 0.000 claims description 5
150000003839 salts Chemical class 0.000 claims description 5
229940075420 xanthine Drugs 0.000 claims description 5
150000002191 fatty alcohols Chemical class 0.000 claims description 4
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 4
239000003755 preservative agent Substances 0.000 claims description 4
125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 4
WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical group [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 claims description 4
239000004299 sodium benzoate Substances 0.000 claims description 4
235000010234 sodium benzoate Nutrition 0.000 claims description 4
125000000217 alkyl group Chemical group 0.000 claims description 3
125000000129 anionic group Chemical group 0.000 claims description 3
239000007864 aqueous solution Substances 0.000 claims description 3
239000012752 auxiliary agent Substances 0.000 claims description 3
125000002091 cationic group Chemical group 0.000 claims description 3
239000003995 emulsifying agent Substances 0.000 claims description 3
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims description 3
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235000013311 vegetables Nutrition 0.000 claims description 3
PPKCADWHBHKMRY-UHFFFAOYSA-N 1-(2-hydroxyethyl)-3-propyl-7h-purine-2,6-dione Chemical compound O=C1N(CCO)C(=O)N(CCC)C2=C1NC=N2 PPKCADWHBHKMRY-UHFFFAOYSA-N 0.000 claims description 2
RJTLNEGJDDHQFR-UHFFFAOYSA-N 1-(2-hydroxypropyl)-3-propyl-7h-purine-2,6-dione Chemical compound O=C1N(CC(C)O)C(=O)N(CCC)C2=C1NC=N2 RJTLNEGJDDHQFR-UHFFFAOYSA-N 0.000 claims description 2
BCCWRHNOLDRMGF-UHFFFAOYSA-N 1-(3-hydroxybutyl)-3-methyl-7h-purine-2,6-dione Chemical compound O=C1N(CCC(O)C)C(=O)N(C)C2=C1NC=N2 BCCWRHNOLDRMGF-UHFFFAOYSA-N 0.000 claims description 2
XYKCXIKMARUABR-UHFFFAOYSA-N 1-(3-hydroxypropyl)-3-(2-methylpropyl)-7h-purine-2,6-dione Chemical compound O=C1N(CCCO)C(=O)N(CC(C)C)C2=C1NC=N2 XYKCXIKMARUABR-UHFFFAOYSA-N 0.000 claims description 2
MLQJLDJELAVLSY-UHFFFAOYSA-N 1-(3-hydroxypropyl)-3-propyl-7h-purine-2,6-dione Chemical compound O=C1N(CCCO)C(=O)N(CCC)C2=C1NC=N2 MLQJLDJELAVLSY-UHFFFAOYSA-N 0.000 claims description 2
KQHIXQSIRSNUOB-UHFFFAOYSA-N 1-(3-hydroxypropyl)-8-methyl-3-(2-methylpropyl)-7h-purine-2,6-dione Chemical compound O=C1N(CCCO)C(=O)N(CC(C)C)C2=C1NC(C)=N2 KQHIXQSIRSNUOB-UHFFFAOYSA-N 0.000 claims description 2
JIBYCMGGUVOCQI-UHFFFAOYSA-N 1-(4-hydroxybutyl)-8-methyl-3-propyl-7h-purine-2,6-dione Chemical compound O=C1N(CCCCO)C(=O)N(CCC)C2=C1NC(C)=N2 JIBYCMGGUVOCQI-UHFFFAOYSA-N 0.000 claims description 2
OQWOQWAYOVAQBU-UHFFFAOYSA-N 1-(4-hydroxypentyl)-3-propyl-7h-purine-2,6-dione Chemical compound O=C1N(CCCC(C)O)C(=O)N(CCC)C2=C1NC=N2 OQWOQWAYOVAQBU-UHFFFAOYSA-N 0.000 claims description 2
DUIPGIVJYFFGRO-UHFFFAOYSA-N 3-butyl-1-(3-hydroxypropyl)-7h-purine-2,6-dione Chemical compound O=C1N(CCCO)C(=O)N(CCCC)C2=C1NC=N2 DUIPGIVJYFFGRO-UHFFFAOYSA-N 0.000 claims description 2
PPVOZPCGSDKACI-UHFFFAOYSA-N 3-ethyl-1-(3-hydroxybutyl)-7h-purine-2,6-dione Chemical compound O=C1N(CCC(C)O)C(=O)N(CC)C2=C1NC=N2 PPVOZPCGSDKACI-UHFFFAOYSA-N 0.000 claims description 2
SOPMHRXOQFAEMG-UHFFFAOYSA-N 3-ethyl-1-(3-hydroxybutyl)-8-methyl-7h-purine-2,6-dione Chemical compound O=C1N(CCC(C)O)C(=O)N(CC)C2=C1NC(C)=N2 SOPMHRXOQFAEMG-UHFFFAOYSA-N 0.000 claims description 2
SNGZYEFKXPNBQB-UHFFFAOYSA-N 8-ethyl-1-(3-hydroxypropyl)-3-propyl-7h-purine-2,6-dione Chemical compound O=C1N(CCCO)C(=O)N(CCC)C2=C1NC(CC)=N2 SNGZYEFKXPNBQB-UHFFFAOYSA-N 0.000 claims description 2
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125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 2
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238000011282 treatment Methods 0.000 description 11
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IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 8
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IVOMOUWHDPKRLL-KQYNXXCUSA-N Cyclic adenosine monophosphate Chemical compound C([C@H]1O2)OP(O)(=O)O[C@H]1[C@@H](O)[C@@H]2N1C(N=CN=C2N)=C2N=C1 IVOMOUWHDPKRLL-KQYNXXCUSA-N 0.000 description 6
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210000001789 adipocyte Anatomy 0.000 description 5
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238000002360 preparation method Methods 0.000 description 4
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150000003626 triacylglycerols Chemical class 0.000 description 4
210000000689 upper leg Anatomy 0.000 description 4
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229960001948 caffeine Drugs 0.000 description 1
VJEONQKOZGKCAK-UHFFFAOYSA-N caffeine Natural products CN1C(=O)N(C)C(=O)C2=C1C=CN2C VJEONQKOZGKCAK-UHFFFAOYSA-N 0.000 description 1
239000004359 castor oil Substances 0.000 description 1
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239000003112 inhibitor Substances 0.000 description 1
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WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 description 1
JCMGISAKAKWXFX-UHFFFAOYSA-N n-[6-amino-1-(2-methylpropyl)-2,4-dioxopyrimidin-5-yl]formamide Chemical compound CC(C)CN1C(N)=C(NC=O)C(=O)NC1=O JCMGISAKAKWXFX-UHFFFAOYSA-N 0.000 description 1
GOQYKNQRPGWPLP-UHFFFAOYSA-N n-heptadecyl alcohol Natural products CCCCCCCCCCCCCCCCCO GOQYKNQRPGWPLP-UHFFFAOYSA-N 0.000 description 1
239000007764 o/w emulsion Substances 0.000 description 1
KHLCTMQBMINUNT-UHFFFAOYSA-N octadecane-1,12-diol Chemical compound CCCCCCC(O)CCCCCCCCCCCO KHLCTMQBMINUNT-UHFFFAOYSA-N 0.000 description 1
VNLRTFSQCPNNIM-UHFFFAOYSA-N octadecyl octanoate Chemical compound CCCCCCCCCCCCCCCCCCOC(=O)CCCCCCC VNLRTFSQCPNNIM-UHFFFAOYSA-N 0.000 description 1
ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
235000021313 oleic acid Nutrition 0.000 description 1
229940055577 oleyl alcohol Drugs 0.000 description 1
XMLQWXUVTXCDDL-UHFFFAOYSA-N oleyl alcohol Natural products CCCCCCC=CCCCCCCCCCCO XMLQWXUVTXCDDL-UHFFFAOYSA-N 0.000 description 1
BARWIPMJPCRCTP-CLFAGFIQSA-N oleyl oleate Chemical compound CCCCCCCC\C=C/CCCCCCCCOC(=O)CCCCCCC\C=C/CCCCCCCC BARWIPMJPCRCTP-CLFAGFIQSA-N 0.000 description 1
239000004006 olive oil Substances 0.000 description 1
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239000002540 palm oil Substances 0.000 description 1
239000000312 peanut oil Substances 0.000 description 1
235000019271 petrolatum Nutrition 0.000 description 1
229920000570 polyether Polymers 0.000 description 1
229920001223 polyethylene glycol Polymers 0.000 description 1
229940068918 polyethylene glycol 400 Drugs 0.000 description 1
229920000136 polysorbate Polymers 0.000 description 1
229910052700 potassium Inorganic materials 0.000 description 1
239000011591 potassium Substances 0.000 description 1
BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 1
QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 description 1
125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 description 1
239000011541 reaction mixture Substances 0.000 description 1
238000001953 recrystallisation Methods 0.000 description 1
230000000717 retained effect Effects 0.000 description 1
238000007363 ring formation reaction Methods 0.000 description 1
229920006395 saturated elastomer Polymers 0.000 description 1
239000008159 sesame oil Substances 0.000 description 1
235000011803 sesame oil Nutrition 0.000 description 1
229940057910 shea butter Drugs 0.000 description 1
230000035483 skin reaction Effects 0.000 description 1
231100000430 skin reaction Toxicity 0.000 description 1
229910052708 sodium Inorganic materials 0.000 description 1
239000011734 sodium Substances 0.000 description 1
239000012279 sodium borohydride Substances 0.000 description 1
229910000033 sodium borohydride Inorganic materials 0.000 description 1
239000011780 sodium chloride Substances 0.000 description 1
JNYAEWCLZODPBN-CTQIIAAMSA-N sorbitan Polymers OCC(O)C1OCC(O)[C@@H]1O JNYAEWCLZODPBN-CTQIIAAMSA-N 0.000 description 1
229940012831 stearyl alcohol Drugs 0.000 description 1
238000007920 subcutaneous administration Methods 0.000 description 1
239000002600 sunflower oil Substances 0.000 description 1
238000003786 synthesis reaction Methods 0.000 description 1
TUNFSRHWOTWDNC-HKGQFRNVSA-N tetradecanoic acid Chemical compound CCCCCCCCCCCCC[14C](O)=O TUNFSRHWOTWDNC-HKGQFRNVSA-N 0.000 description 1
229960004559 theobromine Drugs 0.000 description 1
229960000278 theophylline Drugs 0.000 description 1
230000008719 thickening Effects 0.000 description 1
239000008158 vegetable oil Substances 0.000 description 1
239000010497 wheat germ oil Substances 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/06—Preparations for care of the skin for countering cellulitis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Dermatology (AREA)
Epidemiology (AREA)
Birds (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Cosmetics (AREA)

NL8801651A 1987-06-30 1988-06-29 Cosmetische samenstelling met verdunnende werking en werking tegen cellulitis, waarvan het werkzame bestanddeel een 1-hydroxyalkylxanthine is. NL8801651A (nl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
LU86934A LU86934A1 (fr)	1987-06-30	1987-06-30	Composition cosmetique a action anti-cellulitique et amin-cissante dont le principe actif est une 1-hydroxyalkylxanthine
LU86934		1987-06-30

Publications (1)

Publication Number	Publication Date
NL8801651A true NL8801651A (nl)	1989-01-16

Family

ID=19730941

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NL8801651A NL8801651A (nl)	1987-06-30	1988-06-29	Cosmetische samenstelling met verdunnende werking en werking tegen cellulitis, waarvan het werkzame bestanddeel een 1-hydroxyalkylxanthine is.

Country Status (11)

Country	Link
US (1)	US5053433A (fr)
JP (1)	JPS6422813A (fr)
BE (1)	BE1001278A3 (fr)
CA (1)	CA1328612C (fr)
CH (1)	CH675533A5 (fr)
DE (1)	DE3821972A1 (fr)
FR (1)	FR2617401B1 (fr)
GB (1)	GB2206350B (fr)
IT (1)	IT1217965B (fr)
LU (1)	LU86934A1 (fr)
NL (1)	NL8801651A (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5300298A (en) *	1992-05-06	1994-04-05	The Pennsylvania Research Corporation	Methods of treating obesity with purine related compounds
JPH07187633A (ja) *	1993-12-28	1995-07-25	Univ Nagoya	高周波プラズマによるフラーレン類の合成方法
US5626854A (en) *	1994-03-17	1997-05-06	Kao Corporation	Bath composition
JPH0826961A (ja) *	1994-07-12	1996-01-30	Kao Corp	皮膚外用剤組成物
ATE236611T1 (de) *	1996-05-31	2003-04-15	Dos Santos Mota Joao Carlos	Schlankheitscreme auf pflanzenbasis
BR9602919A (pt) *	1996-06-27	1999-01-12	Cosmeticos Natural Ind Com	Composições cosméticas para o cuidado da pele
JP3768626B2 (ja) *	1996-12-02	2006-04-19	株式会社カネボウ化粧品	脂肪分解促進剤および痩身用皮膚化粧料
FR2863492B1 (fr)	2003-12-10	2007-08-24	Oreal	Utilisation des modulateurs d'aquaglyceroporines comme amincissant
FR2871688B1 (fr)	2004-06-16	2008-05-16	Oreal	Procede pour favoriser la penetration d'un actif et composition permettant sa mise en oeuvre
EP1616551A1 (fr)	2004-07-13	2006-01-18	L'oreal	Procédé de traitement cosmétique pour prévenir ou retarder les signes du vieillissement cutané
US20070048243A1 (en) *	2005-08-30	2007-03-01	L'oreal	Anti-aging composition containing criste marine and padina pavonica extracts
FR2953716B1 (fr)	2009-12-16	2015-03-27	Oreal	Kit de formulation d'un produit cosmetique
FR2967573B1 (fr)	2010-11-23	2012-11-09	Rhodia Poliamida E Especialidades Ltda	Kit cosmetique et utilisation pour ameliorer l'aspect de la peau
FR2968213B1 (fr)	2010-12-03	2014-03-21	Oreal	Utilisation d'une association amincissante
FR2999080B1 (fr)	2012-12-11	2015-03-20	Isp Investments Inc	Utilisation cosmetique de l'association d'un extrait de de germe de caroube et de cafeine en tant qu'agent actif amincissant
FR2999079B1 (fr)	2012-12-11	2015-04-24	Isp Investments Inc	Utilisation cosmetique d'un extrait de germe de caroube en tant qu'agent actif amincissant
CN109689026B (zh)	2016-09-07	2022-08-30	Isp投资有限公司	使用包含生物活性莲提取物的组合物增加脂肪分解的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
LU76148A1 (fr) *	1976-11-08	1978-07-10
FR2490492A1 (fr) *	1980-09-22	1982-03-26	Riker Laboratories Inc	Composition cosmetique pour le traitement local de la cellulite
JPS6110715A (ja) *	1984-06-26	1986-01-18	Fanuc Ltd	絶対位置検出方式

1987
- 1987-06-30 LU LU86934A patent/LU86934A1/fr unknown
1988
- 1988-06-29 IT IT21158/88A patent/IT1217965B/it active
- 1988-06-29 GB GB8815493A patent/GB2206350B/en not_active Expired - Lifetime
- 1988-06-29 FR FR888808747A patent/FR2617401B1/fr not_active Expired - Lifetime
- 1988-06-29 JP JP63162365A patent/JPS6422813A/ja active Pending
- 1988-06-29 CA CA000570713A patent/CA1328612C/fr not_active Expired - Fee Related
- 1988-06-29 CH CH2475/88A patent/CH675533A5/fr not_active IP Right Cessation
- 1988-06-29 DE DE3821972A patent/DE3821972A1/de not_active Withdrawn
- 1988-06-29 NL NL8801651A patent/NL8801651A/nl not_active Application Discontinuation
- 1988-06-29 BE BE8800743A patent/BE1001278A3/fr not_active IP Right Cessation
1990
- 1990-06-18 US US07/538,694 patent/US5053433A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DE3821972A1 (de)	1989-01-12
GB2206350B (en)	1991-05-01
GB2206350A (en)	1989-01-05
IT8821158A0 (it)	1988-06-29
IT1217965B (it)	1990-03-30
CH675533A5 (fr)	1990-10-15
BE1001278A3 (fr)	1989-09-12
JPS6422813A (en)	1989-01-25
GB8815493D0 (en)	1988-08-03
LU86934A1 (fr)	1989-03-08
FR2617401A1 (fr)	1989-01-06
FR2617401B1 (fr)	1992-02-14
US5053433A (en)	1991-10-01
CA1328612C (fr)	1994-04-19

Legal Events

Date	Code	Title	Description
1996-03-01	BV	The patent application has lapsed

Publication	Publication Date	Title
US5053433A (en)	1991-10-01	Cosmetic composition with anticellulitic and slimming action, in which the active principle is a 1-hydroxyalkylxanthine
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