NL8902003A - 2-quantum selectieve nmr sequentie voor het selectief bepalen van een kernmagnetisatieverdeling van een metaboliet. - Google Patents

2-quantum selectieve nmr sequentie voor het selectief bepalen van een kernmagnetisatieverdeling van een metaboliet. Download PDF

Info

Publication number: NL8902003A
Authority: NL; Netherlands
Prior art keywords: quantum; pulses; selective; lactate; metabolite
Prior art date: 1989-08-04

Application number

NL8902003A

Other languages

English (en)

Dutch (nl)

Original Assignee

Philips Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-08-04

Filing date

1989-08-04

Publication date

1991-03-01

1989-08-04 Application filed by Philips Nv filed Critical Philips Nv

1989-08-04 Priority to NL8902003A priority Critical patent/NL8902003A/nl

1990-05-18 Priority to US07/526,404 priority patent/US5081417A/en

1990-07-31 Priority to EP90202083A priority patent/EP0411710B1/en

1990-07-31 Priority to DE69028746T priority patent/DE69028746T2/de

1990-08-01 Priority to JP2204963A priority patent/JP2960124B2/ja

1991-03-01 Publication of NL8902003A publication Critical patent/NL8902003A/nl

Links

239000002207 metabolite Substances 0.000 title claims description 13
230000005415 magnetization Effects 0.000 title claims description 12
238000000034 method Methods 0.000 claims description 17
235000004279 alanine Nutrition 0.000 claims description 15
QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 claims description 14
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical group CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims 2
125000003295 alanine group Chemical group N[C@@H](C)C(=O)* 0.000 claims 1
150000003893 lactate salts Chemical group 0.000 claims 1
JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 description 18
238000001228 spectrum Methods 0.000 description 8
238000010168 coupling process Methods 0.000 description 7
238000005859 coupling reaction Methods 0.000 description 7
239000000126 substance Substances 0.000 description 7
230000008878 coupling Effects 0.000 description 5
238000012545 processing Methods 0.000 description 5
238000005481 NMR spectroscopy Methods 0.000 description 4
238000001727 in vivo Methods 0.000 description 4
238000004611 spectroscopical analysis Methods 0.000 description 4
230000001419 dependent effect Effects 0.000 description 3
230000005284 excitation Effects 0.000 description 3
238000000701 chemical imaging Methods 0.000 description 2
230000001427 coherent effect Effects 0.000 description 2
238000005070 sampling Methods 0.000 description 2
238000000926 separation method Methods 0.000 description 2
210000001519 tissue Anatomy 0.000 description 2
238000012935 Averaging Methods 0.000 description 1
201000009030 Carcinoma Diseases 0.000 description 1
230000005540 biological transmission Effects 0.000 description 1
210000004556 brain Anatomy 0.000 description 1
238000001514 detection method Methods 0.000 description 1
238000002474 experimental method Methods 0.000 description 1
239000003925 fat Substances 0.000 description 1
230000004807 localization Effects 0.000 description 1
238000000691 measurement method Methods 0.000 description 1
210000003205 muscle Anatomy 0.000 description 1
238000001472 pulsed field gradient Methods 0.000 description 1
230000003595 spectral effect Effects 0.000 description 1
238000002560 therapeutic procedure Methods 0.000 description 1
230000007704 transition Effects 0.000 description 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/483—NMR imaging systems with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy
- G01R33/4833—NMR imaging systems with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy using spatially selective excitation of the volume of interest, e.g. selecting non-orthogonal or inclined slices

Landscapes

Physics & Mathematics (AREA)
Optics & Photonics (AREA)
Spectroscopy & Molecular Physics (AREA)
High Energy & Nuclear Physics (AREA)
Condensed Matter Physics & Semiconductors (AREA)
General Physics & Mathematics (AREA)
Magnetic Resonance Imaging Apparatus (AREA)

NL8902003A 1989-08-04 1989-08-04 2-quantum selectieve nmr sequentie voor het selectief bepalen van een kernmagnetisatieverdeling van een metaboliet. NL8902003A (nl)

Priority Applications (5)

Application Number	Priority Date	Filing Date	Title
NL8902003A NL8902003A (nl)	1989-08-04	1989-08-04	2-quantum selectieve nmr sequentie voor het selectief bepalen van een kernmagnetisatieverdeling van een metaboliet.
US07/526,404 US5081417A (en)	1989-08-04	1990-05-18	2-quantum selective mr sequence for selectively determining a nuclear magnetisation distribution of a metabolite
EP90202083A EP0411710B1 (en)	1989-08-04	1990-07-31	2-Quantum selective MR sequence for selectively determining a nuclear magnetisation of a metabolite
DE69028746T DE69028746T2 (de)	1989-08-04	1990-07-31	2-Quantum selektive magnetische Resonanz-Sequenz für die selektive Bestimmung der Kernmagnetisierung von einem Metaboliten
JP2204963A JP2960124B2 (ja)	1989-08-04	1990-08-01	均一安定磁界内に配置された対象の一部の核磁化分布を選択的に決定する方法

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
NL8902003A NL8902003A (nl)	1989-08-04	1989-08-04	2-quantum selectieve nmr sequentie voor het selectief bepalen van een kernmagnetisatieverdeling van een metaboliet.
NL8902003		1989-08-04

Publications (1)

Publication Number	Publication Date
NL8902003A true NL8902003A (nl)	1991-03-01

Family

ID=19855141

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NL8902003A NL8902003A (nl)	1989-08-04	1989-08-04	2-quantum selectieve nmr sequentie voor het selectief bepalen van een kernmagnetisatieverdeling van een metaboliet.

Country Status (5)

Country	Link
US (1)	US5081417A (ja)
EP (1)	EP0411710B1 (ja)
JP (1)	JP2960124B2 (ja)
DE (1)	DE69028746T2 (ja)
NL (1)	NL8902003A (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH03505692A (ja) *	1989-04-29	1991-12-12	ユニバーシティー　オブ　クイーンスランド	スピン共鳴スペクトルの記録方法
DE3914301A1 (de) *	1989-04-29	1990-10-31	Bruker Medizintech	Verfahren zur aufnahme von spinresoneanzspektren und zur spinresonanz-bildgebung
US7018809B1 (en) *	1991-09-19	2006-03-28	Genentech, Inc.	Expression of functional antibody fragments
AU2003256479A1 (en) *	2002-07-11	2004-02-02	The Research Foundation Of State University Of New York	A method of using g-matrix fourier transformation nuclear magnetic resonance (gft nmr) spectroscopy for rapid chemical shift assignment and secondary structure determination of proteins
US7920972B2 (en)	2004-10-18	2011-04-05	The Research Foundation Of State University Of New York	G-matrix Fourier transformation (GFT) nuclear magnetic resonance (NMR) experiments for resonance assignment and structure determination of organic molecules
EP2082218A2 (en) *	2006-10-03	2009-07-29	Oklahoma Medical Research Foundation	Metabolite detection using magnetic resonance

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS60211343A (ja) *	1984-04-05	1985-10-23	Jeol Ltd	核磁気共鳴測定方法
US4680546A (en) *	1986-01-27	1987-07-14	General Electric Company	Methods of, and pulse sequences for, the supression of undesired resonances by generation of quantum coherence in NMR imaging and spectroscopy
US4703270A (en) *	1986-04-18	1987-10-27	The University Of British Columbia	Zero quantum NMR imaging and spectroscopy in a low homogeneity magnetic field
US4843321A (en) *	1988-04-15	1989-06-27	General Electric Company	Method for volume localized spectral editing of NMR signals produced by metabolites containing coupled spins
US4962357A (en) *	1988-07-07	1990-10-09	Sotak Christopher H	Two-dimensional method for spectral editing of NMR signals produced by metabolites containing coupled spins

1989
- 1989-08-04 NL NL8902003A patent/NL8902003A/nl not_active Application Discontinuation
1990
- 1990-05-18 US US07/526,404 patent/US5081417A/en not_active Expired - Fee Related
- 1990-07-31 DE DE69028746T patent/DE69028746T2/de not_active Expired - Fee Related
- 1990-07-31 EP EP90202083A patent/EP0411710B1/en not_active Expired - Lifetime
- 1990-08-01 JP JP2204963A patent/JP2960124B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
JPH0370543A (ja)	1991-03-26
EP0411710A1 (en)	1991-02-06
US5081417A (en)	1992-01-14
DE69028746D1 (de)	1996-11-07
EP0411710B1 (en)	1996-10-02
DE69028746T2 (de)	1997-04-03
JP2960124B2 (ja)	1999-10-06

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Legal Events

Date	Code	Title	Description
1991-03-01	A1B	A search report has been drawn up
1992-04-01	BV	The patent application has lapsed