NL9201716A - Buitenmembraanvesikel dat voorzien is van een groep polypeptiden welke ten minste de immuunwerking van aan membraan gebonden buitenmembraaneiwitten (OMP's) hebben, werkwijze ter bereiding ervan alsmede een vaccin dat een dergelijk buitenmembraanvesikel omvat. - Google Patents

Buitenmembraanvesikel dat voorzien is van een groep polypeptiden welke ten minste de immuunwerking van aan membraan gebonden buitenmembraaneiwitten (OMP's) hebben, werkwijze ter bereiding ervan alsmede een vaccin dat een dergelijk buitenmembraanvesikel omvat. Download PDF

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Publication number
NL9201716A
NL9201716A NL9201716A NL9201716A NL9201716A NL 9201716 A NL9201716 A NL 9201716A NL 9201716 A NL9201716 A NL 9201716A NL 9201716 A NL9201716 A NL 9201716A NL 9201716 A NL9201716 A NL 9201716A
Authority
NL
Netherlands
Prior art keywords
omp
outer membrane
saccharide
polypeptide
membrane vesicle
Prior art date
Application number
NL9201716A
Other languages
English (en)
Dutch (nl)
Original Assignee
Nederlanden Staat
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nederlanden Staat filed Critical Nederlanden Staat
Priority to NL9201716A priority Critical patent/NL9201716A/nl
Priority to US08/411,727 priority patent/US5705161A/en
Priority to AU48351/93A priority patent/AU684720B2/en
Priority to CA002146145A priority patent/CA2146145C/fr
Priority to ES93921120T priority patent/ES2289739T3/es
Priority to AT93921120T priority patent/ATE364702T1/de
Priority to PCT/NL1993/000163 priority patent/WO1994008021A1/fr
Priority to JP6508917A priority patent/JPH08501940A/ja
Priority to PT93921120T priority patent/PT680512E/pt
Priority to EP93921120A priority patent/EP0680512B1/fr
Priority to FI951535A priority patent/FI951535A7/fi
Priority to DE69334147T priority patent/DE69334147T2/de
Priority to DK93921120T priority patent/DK0680512T3/da
Publication of NL9201716A publication Critical patent/NL9201716A/nl
Priority to NO19951181A priority patent/NO321651B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
NL9201716A 1992-10-02 1992-10-02 Buitenmembraanvesikel dat voorzien is van een groep polypeptiden welke ten minste de immuunwerking van aan membraan gebonden buitenmembraaneiwitten (OMP's) hebben, werkwijze ter bereiding ervan alsmede een vaccin dat een dergelijk buitenmembraanvesikel omvat. NL9201716A (nl)

Priority Applications (14)

Application Number Priority Date Filing Date Title
NL9201716A NL9201716A (nl) 1992-10-02 1992-10-02 Buitenmembraanvesikel dat voorzien is van een groep polypeptiden welke ten minste de immuunwerking van aan membraan gebonden buitenmembraaneiwitten (OMP's) hebben, werkwijze ter bereiding ervan alsmede een vaccin dat een dergelijk buitenmembraanvesikel omvat.
JP6508917A JPH08501940A (ja) 1992-10-02 1993-07-30 免疫原性髄膜炎菌のｌｐｓと外膜小胞とそれからのワクチン
PT93921120T PT680512E (pt) 1992-10-02 1993-07-30 Uma molécula provida de imunidade activadora das células e derivada de um lipopolissacarídeo meningocócico, métodos para a sua preparação, uma vesícula de membrana externa provida com grupo de polipepetídeos
CA002146145A CA2146145C (fr) 1992-10-02 1993-07-30 Lps et vesicules de la membrane externe de meningocoques ayant des proprietes immunogenes, et vaccin prepare a partir de ces produits
ES93921120T ES2289739T3 (es) 1992-10-02 1993-07-30 Liposacarido meningococico inmunogenico y vesiculas de membrana externa y vacunas de los mismos.
AT93921120T ATE364702T1 (de) 1992-10-02 1993-07-30 Immunogene meningococcale lps und aussenmembranvesikel und impstoff daraus
PCT/NL1993/000163 WO1994008021A1 (fr) 1992-10-02 1993-07-30 Lipopolysaccharide meningococcique immunogenique ainsi que vesicules de membrane externe et vaccins obtenus
US08/411,727 US5705161A (en) 1992-10-02 1993-07-30 Immunogenic meningococcal LPS and other membrane vesicles and vaccine therefrom
AU48351/93A AU684720B2 (en) 1992-10-02 1993-07-30 Immunogenic meningococcal LPS and outer membrane vesicles and vaccine therefrom
EP93921120A EP0680512B1 (fr) 1992-10-02 1993-07-30 Lipopolysaccharide meningococcique immunogenique ainsi que vesicules de membrane externe et vaccins obtenus
FI951535A FI951535A7 (fi) 1992-10-02 1993-07-30 Immunogeeninen meningokokki -LPS ja siitä saadut ulkomembraanirakkulat ja rokote
DE69334147T DE69334147T2 (de) 1992-10-02 1993-07-30 Immunogene meningococcale lps und aussenmembranvesikel und impstoff daraus
DK93921120T DK0680512T3 (da) 1992-10-02 1993-07-30 Immunogent meningokok LPS og ydermembranvesikler og vaccine deraf
NO19951181A NO321651B1 (no) 1992-10-02 1995-03-28 Immunogent meningokokk-lipopoly-sakkarid, ytter-membranvesikler, samt vaksine fremstilt derav.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL9201716A NL9201716A (nl) 1992-10-02 1992-10-02 Buitenmembraanvesikel dat voorzien is van een groep polypeptiden welke ten minste de immuunwerking van aan membraan gebonden buitenmembraaneiwitten (OMP's) hebben, werkwijze ter bereiding ervan alsmede een vaccin dat een dergelijk buitenmembraanvesikel omvat.
NL9201716 1992-10-02

Publications (1)

Publication Number Publication Date
NL9201716A true NL9201716A (nl) 1994-05-02

Family

ID=19861338

Family Applications (1)

Application Number Title Priority Date Filing Date
NL9201716A NL9201716A (nl) 1992-10-02 1992-10-02 Buitenmembraanvesikel dat voorzien is van een groep polypeptiden welke ten minste de immuunwerking van aan membraan gebonden buitenmembraaneiwitten (OMP's) hebben, werkwijze ter bereiding ervan alsmede een vaccin dat een dergelijk buitenmembraanvesikel omvat.

Country Status (14)

Country Link
US (1) US5705161A (fr)
EP (1) EP0680512B1 (fr)
JP (1) JPH08501940A (fr)
AT (1) ATE364702T1 (fr)
AU (1) AU684720B2 (fr)
CA (1) CA2146145C (fr)
DE (1) DE69334147T2 (fr)
DK (1) DK0680512T3 (fr)
ES (1) ES2289739T3 (fr)
FI (1) FI951535A7 (fr)
NL (1) NL9201716A (fr)
NO (1) NO321651B1 (fr)
PT (1) PT680512E (fr)
WO (1) WO1994008021A1 (fr)

Families Citing this family (43)

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US7118757B1 (en) * 1988-12-19 2006-10-10 Wyeth Holdings Corporation Meningococcal class 1 outer-membrane protein vaccine
BR9609882A (pt) * 1995-08-04 1999-07-27 Univ Guelph Vacina processos para preparar a mesma para tratar uma doença infecciosa para inserir uma molécula de ácido nucleico em uma célula de marcaç o para administrar um agente terapêutico a um hospedeiro e para triar um antígeno imunogênico de um patógeno uso de uma vesícula de membrana composição farmacêutica sistema de liberação de drogas e vesícula de membrana
US20020028215A1 (en) 1999-08-09 2002-03-07 Jagath L. Kadurugamuwa Novel vaccines and pharmaceutical compositions using membrane vesicles of microorganisms, and methods for preparing same
US6872398B2 (en) * 1995-12-22 2005-03-29 The United States Of America As Represented By The Secretary Of The Army Conjugate vaccine against gram-negative bacterial infections
US6645503B1 (en) * 1998-03-10 2003-11-11 Wyeth Holdings Corporation Antigenic conjugates of conserved lipopolysaccharides of gram negative bacteria
GB9823978D0 (en) 1998-11-02 1998-12-30 Microbiological Res Authority Multicomponent meningococcal vaccine
US10967045B2 (en) 1998-11-02 2021-04-06 Secretary of State for Health and Social Care Multicomponent meningococcal vaccine
US6514948B1 (en) * 1999-07-02 2003-02-04 The Regents Of The University Of California Method for enhancing an immune response
US6531131B1 (en) 1999-08-10 2003-03-11 The United States Of America As Represented By The Department Of Health And Human Services Conjugate vaccine for Neisseria meningitidis
EP2364726A3 (fr) 1999-09-30 2011-11-09 Isis Innovation Limited Vaccin contre l'infection Neisseria
ES2519440T3 (es) * 2000-07-27 2014-11-07 Children's Hospital & Research Center At Oakland Vacunas para la protección de amplio espectro contra enfermedades causadas por Neisseria meningitidis
EP1495039A4 (fr) * 2002-03-20 2006-07-26 Univ Emory Mutants de neisseria, lipooligosaccharides et compositions immunogenes
RU2364418C2 (ru) * 2002-08-02 2009-08-20 ГлаксоСмитКлайн Байолоджикалз с.а. ВАКЦИННЫЕ КОМПОЗИЦИИ, СОДЕРЖАЩИЕ ЛИПОПОЛИСАХАРИДЫ ИММУНОТИПА L2 И/ИЛИ L3, ПРОИСХОДЯЩИЕ ИЗ ШТАММА NEISSERIA MENINGITIDIS IgtB-
US20060057160A1 (en) * 2002-08-02 2006-03-16 Ralph Biemans Vaccine composition
GB0220194D0 (en) 2002-08-30 2002-10-09 Chiron Spa Improved vesicles
HUE031886T2 (en) 2002-10-11 2017-08-28 Glaxosmithkline Biologicals Sa Polypeptide vaccines for extensive protection against hypervirulent meningococcal lines
EP1562982B1 (fr) 2002-11-15 2010-05-05 Novartis Vaccines and Diagnostics S.r.l. Proteines de surface inattendues du neisseria meningitidis
GB0227346D0 (en) 2002-11-22 2002-12-31 Chiron Spa 741
EP2172213B1 (fr) 2003-01-30 2013-04-03 Novartis AG Vaccins injectables contre les multiples serogroupes du meningocoque
GB0323103D0 (en) 2003-10-02 2003-11-05 Chiron Srl De-acetylated saccharides
GB0408977D0 (en) 2004-04-22 2004-05-26 Chiron Srl Immunising against meningococcal serogroup Y using proteins
US7537766B2 (en) * 2004-08-30 2009-05-26 Wyeth Neisseria meningitidis inner core lipo-oligosaccharide epitopes, multivalent conjugates thereof and immunogenic compositions thereof
GB0424092D0 (en) 2004-10-29 2004-12-01 Chiron Srl Immunogenic bacterial vesicles with outer membrane proteins
WO2006081259A2 (fr) 2005-01-27 2006-08-03 Children's Hospital & Research Center At Oakland Vaccins vesiculaires a base de gna1870 conferant une protection a large spectre contre les maladies provoquees par neisseria meningitidis
GB0524066D0 (en) 2005-11-25 2006-01-04 Chiron Srl 741 ii
CA2654706A1 (fr) 2006-06-12 2007-12-21 Nathalie Devos Vaccin a base de lipooligosaccharide neisseria meningitidis
CN102356089B (zh) 2008-02-21 2014-02-19 诺华股份有限公司 脑膜炎球菌fHBP多肽
UA99659C2 (uk) * 2008-05-30 2012-09-10 Дзе Ю.Ес.Ей., Ес Репрезентед Бай Дзе Секретарі Оф Дзе Армі, Он Бехаф Оф Уолтер Рід Армі Мультивалентна вакцина з нативних везикул зовнішньої мембрани менінгококів, способи її застосування
EP2411048B1 (fr) 2009-03-24 2020-05-06 GlaxoSmithKline Biologicals SA Protéine de liaison du facteur h méningococcique utilisée comme adjuvant
EP3017826A1 (fr) 2009-03-24 2016-05-11 Novartis AG Combinaisons de protéines de liaison du facteur h méningococcique et de conjugués de saccharides de pneumocoques
CA2761924C (fr) 2009-05-14 2017-10-31 Sanofi Pasteur Vaccin meningocoque a base de lipooligosaccharide (los) provenant de souches modifiees de neisseria meningitidis d'immunotype l6
WO2010134225A1 (fr) * 2009-05-20 2010-11-25 国立大学法人鳥取大学 Procédé de détection d'une infection par une bactérie pathogène neisseria au moyen d'un épitope partiel de la chaîne de sucre et vaccin contre ladite bactérie
CN102596240B (zh) 2009-08-27 2015-02-04 诺华股份有限公司 包括脑膜炎球菌fHBP序列的杂交多肽
EP2470205A1 (fr) 2009-08-27 2012-07-04 Novartis AG Adjuvant contenant de l'aluminium, un oligonucléotide et une polycation
CN102724988B (zh) 2009-09-30 2014-09-10 诺华股份有限公司 脑膜炎球菌fHBP多肽的表达
CA2779816A1 (fr) 2009-10-27 2011-05-05 Novartis Ag Polypeptides fhbp meningococciques modifies
AU2011288203A1 (en) 2010-03-18 2012-08-23 Novartis Ag Adjuvanted vaccines for serogroup B meningococcus
AU2011268507B2 (en) 2010-06-25 2014-08-14 Novartis Ag Combinations of meningococcal factor H binding proteins
JP2015505309A (ja) 2011-12-29 2015-02-19 ノバルティス アーゲー 髄膜炎菌ｈ因子結合タンパク質のアジュバントされた組み合わせ
KR20160127104A (ko) 2014-02-28 2016-11-02 글락소스미스클라인 바이오로지칼즈 에스.에이. 변형된 수막구균 fhbp 폴리펩티드
GB201712824D0 (en) 2017-08-10 2017-09-27 Glaxosmithkline Biologicals Sa Multi-functionalized nOMV Conjugates
SG11202100864VA (en) 2018-08-14 2021-02-25 Evercyte Gmbh Target-specific extracellular vesicles
CA3208643A1 (fr) 2021-01-18 2022-07-21 Conserv Bioscience Limited Compositions immunogenes de coronavirus, methodes et utilisations de celles-ci

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EP0449958B9 (fr) * 1988-12-19 2003-05-28 American Cyanamid Company Vaccin meningocoque de la proteine de la membrane externe de la classe 1
NL9101359A (nl) * 1991-08-07 1993-03-01 Nederlanden Staat Nieuw saccharide-peptide-conjugaat, werkwijze ter bereiding ervan alsmede een vaccin dat een dergelijk saccharide-peptide-conjugaat omvat.

Also Published As

Publication number Publication date
AU4835193A (en) 1994-04-26
ATE364702T1 (de) 2007-07-15
FI951535L (fi) 1995-06-01
DE69334147T2 (de) 2008-02-14
EP0680512B1 (fr) 2007-06-13
EP0680512A1 (fr) 1995-11-08
AU684720B2 (en) 1998-01-08
FI951535A7 (fi) 1995-06-01
DK0680512T3 (da) 2007-10-01
WO1994008021A1 (fr) 1994-04-14
NO321651B1 (no) 2006-06-19
JPH08501940A (ja) 1996-03-05
CA2146145A1 (fr) 1994-04-14
CA2146145C (fr) 2009-10-27
ES2289739T3 (es) 2008-02-01
NO951181D0 (no) 1995-03-28
DE69334147D1 (de) 2007-07-26
NO951181L (no) 1995-06-01
FI951535A0 (fi) 1995-03-31
US5705161A (en) 1998-01-06
PT680512E (pt) 2007-09-25

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