NL960017I2 - Expressie van Factor VIII-activiteit in zoogdiercellen. - Google Patents

Expressie van Factor VIII-activiteit in zoogdiercellen.

Info

Publication number
NL960017I2
NL960017I2 NL960017C NL960017C NL960017I2 NL 960017 I2 NL960017 I2 NL 960017I2 NL 960017 C NL960017 C NL 960017C NL 960017 C NL960017 C NL 960017C NL 960017 I2 NL960017 I2 NL 960017I2
Authority
NL
Netherlands
Prior art keywords
factor
nucleotide sequence
proteins
expression
mammalian cells
Prior art date
Application number
NL960017C
Other languages
English (en)
Other versions
NL960017I1 (nl
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24909926&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NL960017(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Publication of NL960017I1 publication Critical patent/NL960017I1/nl
Publication of NL960017I2 publication Critical patent/NL960017I2/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/644—Coagulation factor IXa (3.4.21.22)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10041—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NL960017C 1985-04-17 1996-07-09 Expressie van Factor VIII-activiteit in zoogdiercellen. NL960017I2 (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72431185A 1985-04-17 1985-04-17

Publications (2)

Publication Number Publication Date
NL960017I1 NL960017I1 (nl) 1996-10-01
NL960017I2 true NL960017I2 (nl) 1997-02-03

Family

ID=24909926

Family Applications (1)

Application Number Title Priority Date Filing Date
NL960017C NL960017I2 (nl) 1985-04-17 1996-07-09 Expressie van Factor VIII-activiteit in zoogdiercellen.

Country Status (4)

Country Link
US (1) US8603777B1 (nl)
NL (1) NL960017I2 (nl)
RU (1) RU2122583C1 (nl)
ZA (1) ZA862768B (nl)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT409379B (de) 1999-06-02 2002-07-25 Baxter Ag Medium zur protein- und serumfreien kultivierung von zellen
EP1982732A3 (en) * 2000-02-11 2011-06-08 Bayer HealthCare LLC Factor VII or VIIA-like conjugates
EP1216709A1 (en) * 2000-12-21 2002-06-26 Boehringer Ingelheim Pharma KG Use of activated coagulation factor VII for treating thrombolytic therapy-induced major bleedings
RU2321633C2 (ru) * 2001-02-16 2008-04-10 Ново Нордиск Хелт Кэр Аг Способ получения витамин к-зависимых белков
IL157842A0 (en) * 2001-03-22 2004-03-28 Novo Nordisk Healthcare Ag Coagulation factor vii derivatives
HK1080372A1 (zh) * 2002-05-01 2006-04-28 Schering Aktiengesellschaft 作为抗凝剂的新型组织因子目标抗体
RU2262947C2 (ru) * 2002-07-24 2005-10-27 Общество с ограниченной ответственностью фирма "Технология-Стандарт" Способ получения тромбиноподобного коагулирующего фермента
RU2331072C2 (ru) * 2003-03-03 2008-08-10 Ланг Флориан sgk1 В КАЧЕСТВЕ ДИАГНОСТИЧЕСКОЙ И ТЕРАПЕВТИЧЕСКОЙ МИШЕНИ
AU2004221758B2 (en) * 2003-03-18 2010-07-22 Novo Nordisk Health Care Ag Method for the production of GLA-residue containing serine proteases
US7897734B2 (en) 2003-03-26 2011-03-01 Novo Nordisk Healthcare Ag Method for the production of proteins
DK1644504T3 (da) * 2003-06-19 2010-05-25 Bayer Healthcare Llc Faktor VII- eller -VIIA-Gla-domænevarianter
GB0324044D0 (en) * 2003-10-14 2003-11-19 Astrazeneca Ab Protein
RU2271219C1 (ru) * 2004-07-28 2006-03-10 Государственное образовательное учреждение высшего профессионального образования "Санкт-Петербургский государственный медицинский университет имени академика И.П. Павлова Министерства здравоохранения Российской Федерации" Способ получения тромбиноподобных ферментов из яда змеи
RU2396086C2 (ru) * 2004-09-10 2010-08-10 Фармаоригин Апс Способы лечения трахеального, бронхиального или альвеолярного кровотечения или кровохарканья
RU2448160C1 (ru) * 2010-11-11 2012-04-20 Закрытое акционерное общество "ГЕНЕРИУМ" РЕКОМБИНАНТНАЯ ПЛАЗМИДНАЯ ДНК pAP271, КОДИРУЮЩАЯ ПОЛИПЕПТИД ФАКТОРА VII СВЕРТЫВАЕМОСТИ КРОВИ ЧЕЛОВЕКА, И ЛИНИЯ КЛЕТОК Mesocricetus auratus ВНК 21 k.13 (2H7) - ПРОДУЦЕНТ РЕКОМБИНАНТНОГО ФАКТОРА VII СВЕРТЫВАЕМОСТИ КРОВИ ЧЕЛОВЕКА

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4399216A (en) * 1980-02-25 1983-08-16 The Trustees Of Columbia University Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US4459288A (en) 1981-05-11 1984-07-10 Baxter Travenol Laboratories, Inc. Therapeutic blood clotting factor compositions and their use
US4382083A (en) 1981-06-25 1983-05-03 Baxter Travenol Laboratories, Inc. Therapeutic method for treating blood-clotting defects with factor VIIa
US4456591A (en) * 1981-06-25 1984-06-26 Baxter Travenol Laboratories, Inc. Therapeutic method for activating factor VII
GR860984B (en) * 1985-04-17 1986-08-18 Zymogenetics Inc Expression of factor vii and ix activities in mammalian cells
GB2215409A (en) * 1988-02-29 1989-09-20 Deere & Co Seals for bearings in baling machines
EP1774017B1 (en) * 2004-07-26 2013-05-15 Pfenex Inc. Process for improved protein expression by strain engineering

Also Published As

Publication number Publication date
ZA862768B (en) 1986-12-30
NL960017I1 (nl) 1996-10-01
RU2122583C1 (ru) 1998-11-27
US8603777B1 (en) 2013-12-10

Similar Documents

Publication Publication Date Title
ATE92105T1 (de) Expression von faktor-vii-aktivitaet in saeugetierzellen.
NL960017I1 (nl) Expressie van Factor VIII-activiteit in zoogdiercellen.
JPS6485096A (en) Hybrid human protein c and biotechnological synthesis thereof
DK0624199T3 (da) Fremgangsmåder til fremstilling af thrombin
UA32548C2 (uk) Ізольована послідовність днк, що кодує epsps фермент, ізольована послідовність днк, що кодує білок, який виявляє epsps активність, рекомбінантна двониткова молекула днк, спосіб одержання генетично трансформованих рослин
ES8705521A1 (es) Un metodo de producir un polipetido similar a factor de necrosis de tumores (tnf) de mamiferos.
DE3786321D1 (de) Expression von protein-c.
DE69131580D1 (de) GDF-1 und UOG1 Proteine
DE69121391D1 (de) Methode zur ortsspezifischen änderung von rna und produktion von dadurch kodierten polypeptiden
ATE319818T1 (de) Polypeptide mit aminopeptidaseaktivität und für diese kodierende nukleinsäuren
DE60033138D1 (de) Polypeptide mit galaktoseoxidaseaktivität und dafür kodierende nukleisäuren
DE69942861D1 (de) Ldcam genannte moleküle
ATE414775T1 (de) Polypeptide mit prolyldipeptidylaminopeptidase- aktivität und dafür kodierende nukleinsäuren
DK288183D0 (da) Fremgangsmade til fremstilling af et oligonucleotidt terapeutisk middel
HUT46061A (en) Dna sequences encoding hirudin-like protein and process for producing such proteins
DE69837475D1 (de) Polypeptide mit aminopeptidaseaktivität und dafür kodierende nukleinsäuren
PT84089B (pt) Sequencias de adn codificando para proteinas possuindo a actividade biologica dos inibidores de husi-tipo i, processos biotecnologicos para a preparacao das referidas proteinas e de composicoes farmaceuticas contendo as referidas proteinas
ATE105480T1 (de) Thrombin bindende substanz und verfahren zu ihrer herstellung.
ATE211390T1 (de) Überlegende thrombomodulinanaloga zur pharmazeutischen verwendung
DE3650477D1 (de) Produktion von Cystinreste enthaltenden aktiven Proteinen
IT1186750B (it) Vettore di clonaggio,molecole di dna ricombinante,ceppi di bacillus subtilis trasformati con dette molecole e metodi per l'espressione di geni eterologhi e produzione e secrezione di proteine codificate da detti geni