NO146774C - Analogifremgangsmaate for fremstilling av terapeutisk aktive piperazin- og piperidinderivater - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive piperazin- og piperidinderivater

Info

Publication number: NO146774C
Authority: NO; Norway
Prior art keywords: preparation; therapeutic active; analogy procedure; active piperazine; piperide
Prior art date: 1976-04-02

Application number

NO771168A

Other languages

English (en)

Norwegian (no)

Other versions

NO771168L (no

NO146774B (no

Inventor

Jan Vandenberk

Ludo E J Kennis

Marcel J M C Van Der Aa

Albert H M Th Van Heertum

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-04-02

Filing date

1977-04-01

Publication date

1982-12-08

1977-04-01 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

1977-10-04 Publication of NO771168L publication Critical patent/NO771168L/no

1982-08-30 Publication of NO146774B publication Critical patent/NO146774B/no

1982-12-08 Publication of NO146774C publication Critical patent/NO146774C/no

Links

GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical compound C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 title 2
239000004615 ingredient Substances 0.000 title 1
230000001225 therapeutic effect Effects 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
- C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/26—Radicals substituted by halogen atoms or nitro radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/08—Radicals containing only hydrogen and carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/26—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/28—Sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Pulmonology (AREA)
Immunology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Plural Heterocyclic Compounds (AREA)
Pyridine Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Thiazole And Isothizaole Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

NO771168A 1976-04-02 1977-04-01 Analogifremgangsmaate for fremstilling av terapeutisk aktive piperazin- og piperidinderivater NO146774C (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US67291976A	1976-04-02	1976-04-02
US75306276A	1976-12-21	1976-12-21

Publications (3)

Publication Number	Publication Date
NO771168L NO771168L (no)	1977-10-04
NO146774B NO146774B (no)	1982-08-30
NO146774C true NO146774C (no)	1982-12-08

Family

ID=27100846

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO771168A NO146774C (no)	1976-04-02	1977-04-01	Analogifremgangsmaate for fremstilling av terapeutisk aktive piperazin- og piperidinderivater

Country Status (31)

Country	Link
JP (1)	JPS52122380A (cs)
AT (1)	AT357541B (cs)
AU (1)	AU515173B2 (cs)
BG (1)	BG36044A3 (cs)
CA (1)	CA1097646A (cs)
CH (1)	CH634317A5 (cs)
CS (1)	CS191337B2 (cs)
CY (1)	CY1210A (cs)
DE (1)	DE2714437A1 (cs)
DK (1)	DK153477C (cs)
EG (1)	EG12722A (cs)
ES (1)	ES456690A1 (cs)
FI (1)	FI66178C (cs)
FR (1)	FR2346350A1 (cs)
GB (1)	GB1579365A (cs)
GR (1)	GR62465B (cs)
HU (1)	HU179491B (cs)
IE (1)	IE44942B1 (cs)
IL (1)	IL51797A (cs)
IT (1)	IT1086841B (cs)
KE (1)	KE3338A (cs)
LU (1)	LU77052A1 (cs)
MY (1)	MY8400208A (cs)
NL (1)	NL190522C (cs)
NO (1)	NO146774C (cs)
NZ (1)	NZ183506A (cs)
PH (1)	PH12951A (cs)
PT (1)	PT66384B (cs)
SE (1)	SE431333B (cs)
SU (1)	SU683621A3 (cs)
YU (1)	YU39992B (cs)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4181802A (en) *	1978-05-11	1980-01-01	Janssen Pharmaceutica N.V.	1-(Heterocyclylalkyl)-1,3-dihydro-2-H-benzimidazole-2-ones
US4254127A (en) *	1980-04-03	1981-03-03	Janssen Pharmaceutica, N.V.	1,3-Dihydro-1-[(1-piperidinyl)alkyl]-2H-benzimidazol-2-one derivatives
JPS57106663A (en) *	1980-12-23	1982-07-02	Kyorin Pharmaceut Co Ltd	1,4-disubstituted piperazine derivative and its preparation
ES8308553A1 (es) *	1982-06-17	1983-09-01	Ferrer Int	"procedimiento de obtencion de nuevos derivados de piperazina".
DE3442757A1 (de) *	1984-11-23	1986-05-28	Wella Ag, 6100 Darmstadt	Verwendung von 2-nitroanilinderivaten in haarfaerbemitteln und neue 2-nitroanilinderivate
JPS625956A (ja) *	1985-07-02	1987-01-12	Terumo Corp	ビニル誘導体およびこれを含有する５−リポキシゲナ−ゼ作用阻害剤
FR2635524B1 (fr) *	1988-08-19	1992-04-24	Adir	Nouveaux derives de benzopyrrolidinone, leur procede de preparation et les compositions pharmaceutiques les renfermant
US5169855A (en) *	1990-03-28	1992-12-08	Du Pont Merck Pharmaceutical Company	Piperidine ether derivatives as psychotropic drugs or plant fungicides
IT1251144B (it) *	1991-07-30	1995-05-04	Boehringer Ingelheim Italia	Derivati del benzimidazolone
CA2132528C (en) *	1992-03-23	2004-06-08	Gerard Frans Maria Jan Cauwenbergh	Agent for use as an anti-irritant
ES2115709T3 (es) *	1992-11-29	1998-07-01	Clariant Gmbh	Nuevas benzofenonas halogenadas asimetricas, y procedimiento para su preparacion.
US5883094A (en) *	1995-04-24	1999-03-16	Pfizer Inc.	Benzimidazolone derivatives with central dopaminergic activity
US5889010A (en) *	1995-05-18	1999-03-30	Pfizer Inc.	Benzimidazole derivatives having dopaminergic activity
IT1292409B1 (it) *	1997-06-24	1999-02-08	Bidachem Spa	Procedimento per la preparazione di oxatomide
GB0009479D0 (en) *	2000-04-17	2000-06-07	Cipla Limited	Antihistaminic compounds
WO2002024661A2 (en) *	2000-09-19	2002-03-28	Boehringer Ingelheim Pharma Gmbh & Co. Kg	New n, n'-disubstituted benzimidazolone derivatives with affinity at the serotonin and dopamine receptors
US6939887B2 (en)	2001-01-30	2005-09-06	Sumitomo Pharmaceuticals Co., Ltd.	Benzimidazolidinone derivatives
EP1618105A1 (en) *	2003-05-01	2006-01-25	Vernalis Research Limited	Azetidinecarboxamide derivatives and their use in the treatment of cb1 receptor mediated disorders
MY150958A (en) *	2005-06-16	2014-03-31	Astrazeneca Ab	Compounds for the treatment of multi-drug resistant bacterial infections
US20100029681A1 (en) *	2006-05-26	2010-02-04	Hassan Pajouhesh	Heterocyclic compounds as calcium channel blockers
WO2010128516A2 (en) *	2009-05-04	2010-11-11	Symed Labs Limited	Process for the preparation of flibanserin involving novel intermediates
CN104926734B (zh) *	2015-07-07	2017-04-05	苏州立新制药有限公司	氟班色林的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2882271A (en) *		1959-04-14		Xcixcxh
US3362956A (en) *	1965-08-19	1968-01-09	Sterling Drug Inc	1-[(heterocyclyl)-lower-alkyl]-4-substituted-piperazines
US3369022A (en) *	1966-11-07	1968-02-13	Robins Co Inc A H	3-piperazinoalkyl-2-benzoxazolinones
JPS5070389A (cs) *	1973-10-30	1975-06-11

1977
- 1977-03-02 YU YU566/77A patent/YU39992B/xx unknown
- 1977-03-04 NZ NZ183506A patent/NZ183506A/xx unknown
- 1977-03-09 ES ES456690A patent/ES456690A1/es not_active Expired
- 1977-03-10 FR FR7707106A patent/FR2346350A1/fr active Granted
- 1977-03-14 BG BG035664A patent/BG36044A3/xx unknown
- 1977-03-14 GR GR52987A patent/GR62465B/el unknown
- 1977-03-18 CA CA274,240A patent/CA1097646A/en not_active Expired
- 1977-03-24 CS CS771972A patent/CS191337B2/cs unknown
- 1977-03-25 CY CY1210A patent/CY1210A/xx unknown
- 1977-03-25 GB GB12754/77A patent/GB1579365A/en not_active Expired
- 1977-03-30 EG EG180/77A patent/EG12722A/xx active
- 1977-03-31 AU AU23824/77A patent/AU515173B2/en not_active Expired
- 1977-03-31 IT IT48768/77A patent/IT1086841B/it active
- 1977-03-31 IL IL51797A patent/IL51797A/xx unknown
- 1977-03-31 LU LU77052A patent/LU77052A1/xx unknown
- 1977-03-31 DE DE19772714437 patent/DE2714437A1/de active Granted
- 1977-03-31 JP JP3556077A patent/JPS52122380A/ja active Granted
- 1977-04-01 AT AT230477A patent/AT357541B/de not_active IP Right Cessation
- 1977-04-01 SE SE7703842A patent/SE431333B/xx not_active IP Right Cessation
- 1977-04-01 FI FI771020A patent/FI66178C/fi not_active IP Right Cessation
- 1977-04-01 CH CH415477A patent/CH634317A5/de not_active IP Right Cessation
- 1977-04-01 DK DK145977A patent/DK153477C/da not_active IP Right Cessation
- 1977-04-01 HU HU77JA782A patent/HU179491B/hu unknown
- 1977-04-01 IE IE699/77A patent/IE44942B1/en not_active IP Right Cessation
- 1977-04-01 NO NO771168A patent/NO146774C/no unknown
- 1977-04-01 NL NLAANVRAGE7703564,A patent/NL190522C/xx not_active IP Right Cessation
- 1977-04-01 PH PH19620A patent/PH12951A/en unknown
- 1977-04-01 SU SU772468056A patent/SU683621A3/ru active
- 1977-04-01 PT PT66384A patent/PT66384B/pt unknown
1983
- 1983-10-24 KE KE3338A patent/KE3338A/xx unknown
1984
- 1984-12-30 MY MY208/84A patent/MY8400208A/xx unknown

Also Published As

Publication number	Publication date
DK153477B (da)	1988-07-18
EG12722A (en)	1981-06-30
IL51797A0 (en)	1977-05-31
FI66178B (fi)	1984-05-31
DK153477C (da)	1988-11-21
YU39992B (en)	1985-06-30
ATA230477A (de)	1979-12-15
ES456690A1 (es)	1978-07-16
PT66384B (en)	1979-01-31
IL51797A (en)	1981-09-13
CY1210A (en)	1984-04-06
CA1097646A (en)	1981-03-17
PH12951A (en)	1979-10-18
SU683621A3 (ru)	1979-08-30
CH634317A5 (en)	1983-01-31
GB1579365A (en)	1980-11-19
IE44942B1 (en)	1982-05-19
AT357541B (de)	1980-07-10
SE7703842L (sv)	1977-10-03
CS191337B2 (en)	1979-06-29
DE2714437C2 (cs)	1989-05-11
HU179491B (en)	1982-10-28
FR2346350A1 (fr)	1977-10-28
LU77052A1 (cs)	1977-07-22
JPS6231707B2 (cs)	1987-07-09
AU515173B2 (en)	1981-03-19
NO771168L (no)	1977-10-04
NZ183506A (en)	1980-04-28
DK145977A (da)	1977-10-03
YU56677A (en)	1983-01-21
FR2346350B1 (cs)	1980-10-17
AU2382477A (en)	1978-10-05
SE431333B (sv)	1984-01-30
DE2714437A1 (de)	1977-10-20
NL190522C (nl)	1994-04-05
KE3338A (en)	1983-11-25
MY8400208A (en)	1984-12-31
IE44942L (en)	1977-10-02
NO146774B (no)	1982-08-30
NL7703564A (nl)	1977-10-04
GR62465B (en)	1979-04-13
FI771020A7 (cs)	1977-10-03
NL190522B (nl)	1993-11-01
BG36044A3 (bg)	1984-08-15
PT66384A (en)	1977-05-01
IT1086841B (it)	1985-05-31
FI66178C (fi)	1984-09-10
JPS52122380A (en)	1977-10-14

Publication	Publication Date	Title
NO147243C (no)	1983-03-02	Analogifremgangsmaate for fremstilling av terapeutisk aktive ftalanderivater
NO149586C (no)	1984-05-16	Analogifremgangsmaate for fremstilling av terapeutisk aktive polypeptider
NO151321C (no)	1985-03-20	Analogifremgangsmaate for fremstilling av terapeutisk aktive karbostyrilderivater
NO151463C (no)	1985-04-17	Analogifremgangsmaate for fremstilling av terapeutisk aktive kinazolinderivater
NO145915C (no)	1982-06-23	Analogifremgangsmaate for fremstilling av fysiologisk aktive karboksyalkylacylaminosyrer
NO151411C (no)	1985-04-10	Analogifremgangsmaate for fremstilling av terapeutisk aktive 1-aryloksy-2-hydroksy-3-alkylenaminopropan-derivater
NO152899C (no)	1985-12-11	Analogifremgangsmaate for fremstilling av terapeutisk aktive glycerolderivater.
NO148150C (no)	1983-08-24	Analogifremstilling av terapeutisk aktive piperazinderivater
NO143219C (no)	1981-01-07	Analogifremgangsmaate for fremstilling av terapeutisk aktive forbindelser.
NO800881L (no)	1980-09-29	Analogifremgangsmaate for fremstilling av terapeutisk aktive kinolonderivater
NO148416C (no)	1983-10-12	Analogifremgangsmaate for fremstilling av terapeutisk aktive tiazolidin-, morfolin- og tiazan-derivater
NO147913C (no)	1983-07-06	Analogifremgangsmaate for fremstilling av fysiologisk aktive pyrazolopyridiner
NO145198C (no)	1982-02-03	Analogifremgangsmaate til fremstilling av terapeutisk aktivt 1,2-benzisotia-zolinon-3
NO151239C (no)	1985-03-06	Analogifremgangsmaate for fremstilling av terapeutisk aktive 2-fenyliminoimidazolidiner
NO149313C (no)	1984-03-28	Analogifremgangsmaate for fremstilling av terapeutisk aktive pyridobenzodiazepiner
NO149037C (no)	1984-02-01	Analogifremgangsmaate for fremstilling av terapeutisk aktive pyridobenzodiazepiner
NO145951C (no)	1982-06-30	Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazolinderivater
NO148488C (no)	1983-10-19	Analogifremgangsmaate til fremstilling av terapeutisk aktive acyl-benzimidazol-2-derivater
NO148291C (no)	1983-09-14	Analogifremgangsmaate til fremstilling av terapeutisk aktive basisk substituerte teofyllinderivater
NO145163C (no)	1982-01-27	Analogifremgangsmaate til fremstilling av terapeutisk aktive antitumorglykosider
NO146710C (no)	1982-11-24	Analogifremgangsmaate for fremstilling av terapeutisk aktive fenylpiperazinderivater
NO145540C (no)	1982-04-14	Fremgangsmaate for fremstilling av terapeutisk aktive polyribonukleotider
NO152172C (no)	1985-08-14	Analogifremgangsmaate for fremstilling av terapeutisk aktive spiro-kinolyl-hydantoin-derivater
NO801989L (no)	1981-01-05	Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrimidopyrimidiner
NO152556C (no)	1985-10-16	Analogifremgangsmaate for fremstilling av terapeutisk aktive antracen-biskarbonylhydrazoner