NO162194C - Radioakt. oestradienderivat, fremgm. ved dets fremst., middel for radioimmunologisk paavisn. og best. in vitro av ikke-radioaktivt 17beta-hydroksy-11beta-(4-dimethylaminofenyl)-17beta-(prop-1-ynyl)-oestra-4,9-dien-3-on og dets metab. - Google Patents

Radioakt. oestradienderivat, fremgm. ved dets fremst., middel for radioimmunologisk paavisn. og best. in vitro av ikke-radioaktivt 17beta-hydroksy-11beta-(4-dimethylaminofenyl)-17beta-(prop-1-ynyl)-oestra-4,9-dien-3-on og dets metab.

Info

Publication number: NO162194C
Authority: NO; Norway
Prior art keywords: 17beta; radioactive; ynyl; dimethylaminophenyl; prop
Prior art date: 1983-06-14

Application number

NO841798A

Other languages

English (en)

Norwegian (no)

Other versions

NO841798L (no

NO162194B (no

Inventor

Alain Jouquey

Jean-Noel Veltz

Jean Salmon

Michel Mouren

Original Assignee

Roussel Uclaf

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-06-14

Filing date

1984-05-04

Publication date

1989-11-22

1984-05-04 Application filed by Roussel Uclaf filed Critical Roussel Uclaf

1984-12-17 Publication of NO841798L publication Critical patent/NO841798L/no

1989-08-14 Publication of NO162194B publication Critical patent/NO162194B/no

1989-11-22 Publication of NO162194C publication Critical patent/NO162194C/no

Links

238000000338 in vitro Methods 0.000 title 1
YZCKVEUIGOORGS-NJFSPNSNSA-N Tritium Chemical compound [3H] YZCKVEUIGOORGS-NJFSPNSNSA-N 0.000 abstract 2
125000004432 carbon atom Chemical group C* 0.000 abstract 2
230000002285 radioactive effect Effects 0.000 abstract 2
229910052722 tritium Inorganic materials 0.000 abstract 2
125000002252 acyl group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
239000013060 biological fluid Substances 0.000 abstract 1
150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
150000002158 estradienes Chemical class 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
150000002431 hydrogen Chemical group 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
239000002207 metabolite Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0493—Steroids, e.g. cholesterol, testosterone
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
- C07J41/0016—Oximes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
- C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/534—Production of labelled immunochemicals with radioactive label
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/743—Steroid hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Hematology (AREA)
Organic Chemistry (AREA)
Urology & Nephrology (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Biochemistry (AREA)
Food Science & Technology (AREA)
Analytical Chemistry (AREA)
Microbiology (AREA)
Cell Biology (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Biotechnology (AREA)
Optics & Photonics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Endocrinology (AREA)
Steroid Compounds (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

NO841798A 1983-06-14 1984-05-04 Radioakt. oestradienderivat, fremgm. ved dets fremst., middel for radioimmunologisk paavisn. og best. in vitro av ikke-radioaktivt 17beta-hydroksy-11beta-(4-dimethylaminofenyl)-17beta-(prop-1-ynyl)-oestra-4,9-dien-3-on og dets metab. NO162194C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8309812A FR2549067B1 (fr)	1983-06-14	1983-06-14	Derives estradieniques radioactifs marques au tritium, leur procede de preparation et leur application pour l'etude et le dosage radio-immunologique de steroides dans les fluides biologiques

Publications (3)

Publication Number	Publication Date
NO841798L NO841798L (no)	1984-12-17
NO162194B NO162194B (no)	1989-08-14
NO162194C true NO162194C (no)	1989-11-22

Family

ID=9289759

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO841798A NO162194C (no)	1983-06-14	1984-05-04	Radioakt. oestradienderivat, fremgm. ved dets fremst., middel for radioimmunologisk paavisn. og best. in vitro av ikke-radioaktivt 17beta-hydroksy-11beta-(4-dimethylaminofenyl)-17beta-(prop-1-ynyl)-oestra-4,9-dien-3-on og dets metab.

Country Status (9)

Country	Link
US (1)	US4661295A (de)
EP (1)	EP0135400B1 (de)
JP (2)	JPS6011499A (de)
AT (1)	ATE34752T1 (de)
CA (2)	CA1222744A (de)
DE (1)	DE3471660D1 (de)
FI (1)	FI83785C (de)
FR (1)	FR2549067B1 (de)
NO (1)	NO162194C (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2785023B2 (ja) *	1987-12-30	1998-08-13	ルセル―ユクラフ	１７α位置を置換された１７β―ＯＨ―１９―ノルステロイドの新誘導体、その製造方法、その薬剤としての使用及びそれを含有する製薬組成物
DE59010853D1 (de) *	1989-08-04	1998-12-03	Schering Ag	11 Beta-Aryl-gona-4,9-dien-3-one
US5407928A (en) *	1990-08-15	1995-04-18	Schering Aktiengesellschaft	11β-aryl-gona-4,9-dien-3-ones
ATE156836T1 (de) *	1994-05-19	1997-08-15	Akzo Nobel Nv	11,21-bisphenyl-19-nor-pregnan derivate
AU2019351004B2 (en) *	2018-09-28	2023-09-14	The Regents Of The University Of Michigan	Halogenated cholesterol analogues and methods of making and using same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2414515A1 (fr) *	1978-01-11	1979-08-10	Roussel Uclaf	Steroides marques au tritium, leur procede de preparation et leur application dans la synthese de derives de l'estrane marques au tritium
FR2430953A1 (fr) *	1978-07-13	1980-02-08	Roussel Uclaf	Nouveaux derives 3,20-dioxo 4,9-diene 21-hydroxyle, leur procede de preparation et leur application comme medicaments
ZA8231B (en) *	1981-01-09	1982-11-24	Roussel Uclaf	New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained

1983
- 1983-06-14 FR FR8309812A patent/FR2549067B1/fr not_active Expired
1984
- 1984-05-04 NO NO841798A patent/NO162194C/no unknown
- 1984-06-12 JP JP59119240A patent/JPS6011499A/ja active Pending
- 1984-06-13 EP EP84401203A patent/EP0135400B1/de not_active Expired
- 1984-06-13 DE DE8484401203T patent/DE3471660D1/de not_active Expired
- 1984-06-13 CA CA000456496A patent/CA1222744A/fr not_active Expired
- 1984-06-13 AT AT84401203T patent/ATE34752T1/de not_active IP Right Cessation
- 1984-06-13 FI FI842398A patent/FI83785C/fi not_active IP Right Cessation
- 1984-06-14 US US06/620,454 patent/US4661295A/en not_active Expired - Fee Related
- 1984-06-14 JP JP59120900A patent/JPS6034989A/ja active Pending
1987
- 1987-02-17 CA CA000529936A patent/CA1242695A/fr not_active Expired

Also Published As

Publication number	Publication date
FR2549067A1 (fr)	1985-01-18
EP0135400A2 (de)	1985-03-27
FI842398L (fi)	1984-12-15
JPS6034989A (ja)	1985-02-22
JPS6011499A (ja)	1985-01-21
US4661295A (en)	1987-04-28
EP0135400A3 (en)	1985-08-14
ATE34752T1 (de)	1988-06-15
EP0135400B1 (de)	1988-06-01
FI83785C (fi)	1991-08-26
NO841798L (no)	1984-12-17
DE3471660D1 (en)	1988-07-07
FR2549067B1 (fr)	1985-12-27
FI842398A0 (fi)	1984-06-13
FI83785B (fi)	1991-05-15
NO162194B (no)	1989-08-14
CA1222744A (fr)	1987-06-09
CA1242695A (fr)	1988-10-04

Publication	Publication Date	Title
ATE29265T1 (de)	1987-09-15	Neue redox-indikatoren.
ES512381A0 (es)	1983-03-01	"procedimiento de preparacion de disacaridos".
DK374083A (da)	1983-08-16	Cyclovitamin-d forbindelser
ES504702A0 (es)	1982-08-16	Procedimiento de fabricacion y de aplicacion de derivados iridoides reactivos
DE3471660D1 (en)	1988-07-07	Estradiene derivatives labelled with tritium, their preparation and intermediates for their preparation, and their utilization in the study and in the determination of steroids in biological fluids
DE3262905D1 (en)	1985-05-09	Chlorinated beta-ketoesters, their preparation and their use
FI842397A0 (fi)	1984-06-13	Foerfarande foer framstaellning av radioaktiva steroider och deras mellanprodukter, deras laemplighet foer paovisande av glukokortikoidreceptorer och bestaemmande av antalet bindningstaellen.
NO154880C (no)	1987-01-07	Fremgangsmaate for fremstilling av monoalkyletere av hydrokinonforbindelser.
NO824253L (no)	1983-06-20	2-amino-1-(1,3-dioxolan-4-yl)-ethanolforbindelser, fremstilling av disse og anvendelse av disse som utgangsmaterialer
RO83669A (ro)	1984-06-21	Procedeu de preparare a unor derivati ai 6-alfa-metilhidrocortizonului
IE791781L (en)	1980-03-21	4, 5-methano-bufadienolide rhamnosides
PT74343B (fr)	1984-05-30	Nouveau procede de preparation de 17 alpha-hydroxy 17 beta- -hydroxyacetyl steroides
GB1538037A (en)	1979-01-10	Process for the preparation of prostaglandins
ES478210A1 (es)	1979-11-01	Un procedimiento de preparacion de derivados de la xantona.
JPS5699500A (en)	1981-08-10	Novel corticoidd177thioacetal* its manufacture and antiinflammatory medicine containing it
KR830005179A (ko)	1983-08-03	아세트 아닐리드의 제조방법
KR870000303A (ko)	1987-02-17	신규 피라졸린 화합물의 제조방법
ES480141A1 (es)	1980-04-01	Procedimiento para la preparacion de derivados 6-oxigenados-3, 20-dioxo-pregnano.