NO169965C - Analogifremgangsmaate for fremstilling av terapeutisk aktive 5-substituerte (4,5-c)imidazopyridiner - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive 5-substituerte (4,5-c)imidazopyridiner

Info

Publication number
NO169965C
NO169965C NO891058A NO891058A NO169965C NO 169965 C NO169965 C NO 169965C NO 891058 A NO891058 A NO 891058A NO 891058 A NO891058 A NO 891058A NO 169965 C NO169965 C NO 169965C
Authority
NO
Norway
Prior art keywords
carbon atoms
alkyl
substituted
group
halogen
Prior art date
Application number
NO891058A
Other languages
English (en)
Norwegian (no)
Other versions
NO169965B (no
NO891058L (no
NO891058D0 (no
Inventor
Ish K Khanna
Roger Nosal
Richard Mathias Weier
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/167,671 external-priority patent/US4914108A/en
Application filed by Searle & Co filed Critical Searle & Co
Publication of NO891058D0 publication Critical patent/NO891058D0/no
Publication of NO891058L publication Critical patent/NO891058L/no
Publication of NO169965B publication Critical patent/NO169965B/no
Publication of NO169965C publication Critical patent/NO169965C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO891058A 1988-03-14 1989-03-13 Analogifremgangsmaate for fremstilling av terapeutisk aktive 5-substituerte (4,5-c)imidazopyridiner NO169965C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/167,671 US4914108A (en) 1988-03-14 1988-03-14 5-substituted(4,5-c)imidazopyridine compounds which have useful platelet activating factor antagonistic activity
US07/317,871 US5019581A (en) 1988-03-14 1989-03-06 5-substituted (4,5-c) imidazopyridine compounds which have useful platelet activating factor antagonistic activity

Publications (4)

Publication Number Publication Date
NO891058D0 NO891058D0 (no) 1989-03-13
NO891058L NO891058L (no) 1989-09-15
NO169965B NO169965B (no) 1992-05-18
NO169965C true NO169965C (no) 1992-08-26

Family

ID=26863369

Family Applications (1)

Application Number Title Priority Date Filing Date
NO891058A NO169965C (no) 1988-03-14 1989-03-13 Analogifremgangsmaate for fremstilling av terapeutisk aktive 5-substituerte (4,5-c)imidazopyridiner

Country Status (15)

Country Link
US (1) US5019581A (fr)
EP (1) EP0344414B1 (fr)
JP (1) JP2714426B2 (fr)
KR (1) KR890014537A (fr)
AT (1) ATE112774T1 (fr)
AU (1) AU625058B2 (fr)
CA (1) CA1337072C (fr)
DE (1) DE68918755T2 (fr)
DK (1) DK169872B1 (fr)
ES (1) ES2061753T3 (fr)
FI (1) FI91407C (fr)
IL (1) IL89588A0 (fr)
NO (1) NO169965C (fr)
NZ (1) NZ228336A (fr)
PH (1) PH26967A (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5302601A (en) * 1988-03-14 1994-04-12 G. D. Searle & Co. 5-substituted imidazo[4,5-c]pyridines
US5227384A (en) * 1988-03-14 1993-07-13 G. D. Searle & Co. 5-substituted [4,5-c] imidazopyridines and pharmaceutical use thereof
US4990518A (en) * 1989-09-13 1991-02-05 G. D. Searle & Co. Pharmacologically active heteroaryl substituted imidazo (4,5-c) pyridines
GB9116056D0 (en) * 1991-07-24 1991-09-11 British Bio Technology Compounds
US5223539A (en) * 1991-11-22 1993-06-29 G. D. Searle & Co. N,n-di-alkyl(phenoxy)benzamide derivatives
US5208242A (en) * 1992-08-26 1993-05-04 G. D. Searle & Co. 5-substituted-4-phenyl-5H-imidazo[4,5-c]pyridine derivatives
US5262426A (en) * 1993-01-22 1993-11-16 G. D. Searle & Co. N,N'-cycloalkyl/alkyl carboxamide 4H-imidazo-[4,5-b]pyridine compounds as PAF antagonists
US5360907A (en) * 1993-06-14 1994-11-01 G.D. Searle & Co. Pyrrolo[3,2-B]pyridinylalkyl benzamide derivatives
US5496855A (en) * 1995-01-27 1996-03-05 Smithkline Beecham Corp. Anti-inflammatory compounds
GB0215293D0 (en) * 2002-07-03 2002-08-14 Rega Foundation Viral inhibitors
JP4970048B2 (ja) * 2003-12-22 2012-07-04 カトリーケ・ウニフェルジテイト・ルーベン・カー・イュー・ルーベン・アール・アンド・ディ イミダゾ［４，５−ｃ］ピリジン化合物および抗ウイルス治療の方法
DE602005013580D1 (de) * 2004-12-21 2009-05-07 Leuven K U Res & Dev Imidazoä4,5-cüpyridinverbindung und verfahren zur antiviralen behandlung
TW200808695A (en) * 2006-06-08 2008-02-16 Amgen Inc Benzamide derivatives and uses related thereto
TWI360549B (en) * 2006-07-07 2012-03-21 Gilead Sciences Inc Novel pyridazine compound and use thereof
UA99466C2 (en) 2007-07-06 2012-08-27 Гилиад Сайенсиз, Инк. Crystalline pyridazine compound

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4281005A (en) * 1979-03-05 1981-07-28 Merck & Co., Inc. Novel 2-pyridylimidazole compounds
DE2927987A1 (de) * 1979-07-11 1981-02-05 Thomae Gmbh Dr K Neue 2-alkoxyphenyl-imidazo eckige klammer auf 4,5-b eckige klammer zu pyridine, deren herstellung und deren verwendung als arzneimittel
ZA832938B (en) * 1982-05-03 1984-12-24 Lilly Co Eli 2-phenylimidazo(4,5-c)pyridines
US4804658A (en) * 1986-09-15 1989-02-14 G. D. Searle & Co. Imidazopyridine derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
IL89588A0 (en) 1989-09-10
FI91407B (fi) 1994-03-15
NO169965B (no) 1992-05-18
NO891058L (no) 1989-09-15
AU3127089A (en) 1989-09-14
DE68918755D1 (de) 1994-11-17
DK121189D0 (da) 1989-03-13
JPH01316378A (ja) 1989-12-21
DE68918755T2 (de) 1995-03-09
AU625058B2 (en) 1992-07-02
NO891058D0 (no) 1989-03-13
US5019581A (en) 1991-05-28
FI891200A7 (fi) 1989-09-15
ATE112774T1 (de) 1994-10-15
NZ228336A (en) 1992-01-29
KR890014537A (ko) 1989-10-24
DK121189A (da) 1989-09-15
EP0344414B1 (fr) 1994-10-12
CA1337072C (fr) 1995-09-19
ES2061753T3 (es) 1994-12-16
DK169872B1 (da) 1995-03-20
EP0344414A1 (fr) 1989-12-06
FI891200A0 (fi) 1989-03-14
PH26967A (en) 1992-12-28
FI91407C (fi) 1994-06-27
JP2714426B2 (ja) 1998-02-16

Similar Documents

Publication Publication Date Title
NO169965C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 5-substituerte (4,5-c)imidazopyridiner
DE3881472D1 (de) Heterocyclische verbindungen mit therapeutischer wirkung.
HUP0302167A2 (hu) Metabotropikus glutamát receptor antagonista hatású kinolinszármazékok, a vegyületeket tartalmazó gyógyszerkészítmények és eljárás előállításukra
ATE73815T1 (de) Adenosin-derivate und pharmazeutische zusammenstellungen, welche diese als aktiven bestandteil enthalten.
DK1583524T3 (da) Bis(thiohydrazidamid)-forbindelser til behandling af multilægemiddel-resistent cancer
NO991423L (no) Kinolinderivater som inhiberer effekten av vekstfaktorer som VEGF
AR011174A1 (es) Compuestos de pirazina, composiciones farmaceuticas que los contienen, su uso en la peparacion de medicamentos y proceso para prepararlos
EA200501315A1 (ru) 8-ЗАМЕЩЁННЫЕ ПРОИЗВОДНЫЕ 6,7,8,9-ТЕТРАГИДРОПИРИМИДО[1,2-a]ПИРИМИДИН-4-ОНА
CY1108913T1 (el) Παραγωγα 4 (φαινυλ-πιπεραζινυλ-μεθυλ) βενζαμιδιου και η χρηση τους για τη θεραπευτικη αντιμετωπιση του πονου, του αγχους ή γαστρεντερικων διαταραχων
DE69817393D1 (de) Neue heterozyklische verbindungen
EA200601192A1 (ru) ЗАМЕЩЁННЫЕ ПРОИЗВОДНЫЕ 8'-ПИРИ(МИ)ДИНИЛДИГИДРОСПИРО[ЦИКЛОАЛКИЛАМИН]ПИРИМИДО[1,2-a]ПИРИМИДИН-6-ОНА
NO170084C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive dihydropyridinderivater
NO168585C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrazolopyridiner
CA2393710A1 (fr) Inhibiteurs de caspase et utilisations correspondantes
FI112485B (fi) Uusia 1,4-dihydro-4-okso-1,8-naftyridiinijohdannaisia, menetelmä niiden valmistamiseksi ja kasvaintenvastaisia aineita
BR0113078A (pt) Uso de um composto, composto, processo para a preparação do mesmo, composição farmacêutica, e, método para produzir um efeito antiangiogênico e/ou redutor da permeabilidade vascular em um animal de sangue quente
ATE186301T1 (de) An den positionen 2 und 9 substituierte 4h-pyrido-(1,2-a)pyrimidin-4-one
AR035465A1 (es) Compuestos de imidazopiridina, procesos para su preparacion,formulacion farmaceutica, usos de estos compuestos para la fabricacion de medicamentos e intermediarios
YU58301A (sh) 2-aminopiridini koji sadrže supstituente sa kondenzovanim prstenom
CA2429440A1 (fr) Composes dihalogenes
EA200101204A1 (ru) Новые бициклические соединения аминопиразинона, способ их получения и содержащие их фармацевтические композиции
NO168707C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive heterotetracykliske laktamderivater.
ATE205209T1 (de) Chinolincarbonsäurederivate und ihre salze
ATE226196T1 (de) Neue cyclische aminophenylessigsäurederivate, ihre herstellung und immunomodulatoren , welche diese als aktiven bestandteil enthalten
FI853866A0 (fi) 2-pyridin-tiol-derivat, foerfarande foer framstaellning av dessa samt farmaceutiska foereningar innehaollande dessa.