NO173365C - Fremgangsm}te for fremstilling av et i det vesentlige ikke-sviende, vandig, antiinflammatorisk steroidpreparat egnet for intranasal administerering - Google Patents

Fremgangsm}te for fremstilling av et i det vesentlige ikke-sviende, vandig, antiinflammatorisk steroidpreparat egnet for intranasal administerering

Info

Publication number: NO173365C
Authority: NO; Norway
Prior art keywords: preparation; inflammatory steroid; amount; intranasal administration; starchy
Prior art date: 1986-05-22

Application number

NO872127A

Other languages

English (en)

Norwegian (no)

Other versions

NO872127L (no

NO173365B (no

NO872127D0 (no

Inventor

Eric Joel Benjamin

Shabbir Tyabji Anik

Ya-Yin Tracy Lin

Original Assignee

Syntex Pharma Int

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-05-22

Filing date

1987-05-21

Publication date

1993-12-08

1987-05-21 Application filed by Syntex Pharma Int filed Critical Syntex Pharma Int

1987-05-21 Publication of NO872127D0 publication Critical patent/NO872127D0/no

1987-11-23 Publication of NO872127L publication Critical patent/NO872127L/no

1993-08-30 Publication of NO173365B publication Critical patent/NO173365B/no

1993-12-08 Publication of NO173365C publication Critical patent/NO173365C/no

Links

239000002260 anti-inflammatory agent Substances 0.000 title abstract 3
238000000034 method Methods 0.000 title 1
DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 abstract 3
208000002193 Pain Diseases 0.000 abstract 1
229920002565 Polyethylene Glycol 400 Polymers 0.000 abstract 1
229920001213 Polysorbate 20 Polymers 0.000 abstract 1
239000003963 antioxidant agent Substances 0.000 abstract 1
230000003078 antioxidant effect Effects 0.000 abstract 1
238000009472 formulation Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
239000006179 pH buffering agent Substances 0.000 abstract 1
239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 abstract 1
235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 abstract 1
229940068977 polysorbate 20 Drugs 0.000 abstract 1
239000003755 preservative agent Substances 0.000 abstract 1
230000002335 preservative effect Effects 0.000 abstract 1
239000003381 stabilizer Substances 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Otolaryngology (AREA)
Chemical Kinetics & Catalysis (AREA)
Pain & Pain Management (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Steroid Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

NO872127A 1986-05-22 1987-05-21 Fremgangsm}te for fremstilling av et i det vesentlige ikke-sviende, vandig, antiinflammatorisk steroidpreparat egnet for intranasal administerering NO173365C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/866,171 US4782047A (en)	1986-05-22	1986-05-22	Aqueous steroid formulations for nasal administration

Publications (4)

Publication Number	Publication Date
NO872127D0 NO872127D0 (no)	1987-05-21
NO872127L NO872127L (no)	1987-11-23
NO173365B NO173365B (no)	1993-08-30
NO173365C true NO173365C (no)	1993-12-08

Family

ID=25347059

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO872127A NO173365C (no)	1986-05-22	1987-05-21	Fremgangsm}te for fremstilling av et i det vesentlige ikke-sviende, vandig, antiinflammatorisk steroidpreparat egnet for intranasal administerering

Country Status (19)

Country	Link
US (1)	US4782047A (da)
EP (1)	EP0246652B1 (da)
JP (1)	JP2521291B2 (da)
KR (1)	KR950008308B1 (da)
AT (1)	ATE65183T1 (da)
AU (1)	AU609718B2 (da)
CA (1)	CA1288048C (da)
DE (1)	DE3771389D1 (da)
DK (1)	DK175238B1 (da)
ES (1)	ES2031467T3 (da)
FI (1)	FI88459C (da)
GR (1)	GR3002317T3 (da)
HK (1)	HK39094A (da)
IE (1)	IE60259B1 (da)
IL (1)	IL82615A (da)
IT (1)	IT1205667B (da)
NO (1)	NO173365C (da)
NZ (1)	NZ220394A (da)
ZA (1)	ZA873663B (da)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4983595A (en) *	1986-05-22	1991-01-08	Syntex (U.S.A.) Inc.	Aqueous steroid formulations for nasal administration
JPH0311016A (ja) *	1989-06-09	1991-01-18	Tokyo Tanabe Co Ltd	ピリド［１，２―ａ］ピリミジン誘導体の水性製剤
GB9103824D0 (en) *	1991-02-23	1991-04-10	Fisons Ag	Formulation
US5338732A (en) *	1991-06-18	1994-08-16	Bristol-Myers Squibb Company	Megestrol acetate formulation
KR100217258B1 (ko) *	1993-10-21	1999-09-01	나까도미 히로다카	경비조성물
US5762917A (en) *	1994-09-27	1998-06-09	Virotex Corporation	Method and composition for cleansing wounds with minimal cytotoxicity for minimal scarring
US5976573A (en) *	1996-07-03	1999-11-02	Rorer Pharmaceutical Products Inc.	Aqueous-based pharmaceutical composition
US8466134B1 (en)	1998-06-26	2013-06-18	Athena Neurosciences, Inc.	Aqueous compositions containing corticosteroids for nasal and pulmonary delivery
US6241969B1 (en)	1998-06-26	2001-06-05	Elan Corporation Plc	Aqueous compositions containing corticosteroids for nasal and pulmonary delivery
GB9918559D0 (en) *	1999-08-07	1999-10-06	Glaxo Wellcome Kk	Novel pharmaceutical formulation
US20060083691A1 (en) *	2000-05-10	2006-04-20	Wermeling Daniel P	Intranasal opioid compositions, delivery devices and methods of using same
US20040115133A1 (en) *	2000-05-10	2004-06-17	Wermeling Daniel P.	Intranasal opioid compositions
US6610271B2 (en) *	2000-05-10	2003-08-26	University Of Kentucky Research Foundation	System and method for intranasal administration of lorazepam
EP1315533A4 (en) *	2000-08-15	2007-06-27	Univ Kentucky Res Found	PROGRAMMABLE MULTI-DOSE DEVICE FOR INTRANASAL MEDICINE ADMINISTRATION
US20040176359A1 (en) *	2001-02-20	2004-09-09	University Of Kentucky Research Foundation	Intranasal Benzodiazepine compositions
GB2389530B (en)	2002-06-14	2007-01-10	Cipla Ltd	Pharmaceutical compositions
ES2405287T3 (es)	2002-08-01	2013-05-30	Eisai Inc.	Tratamiento mejorado del cáncer con glutamina
US7148211B2 (en) *	2002-09-18	2006-12-12	Genzyme Corporation	Formulation for lipophilic agents
US7404489B1 (en)	2003-03-04	2008-07-29	Qol Medical, Llc	Cyanocobalamin low viscosity aqueous formulations for intranasal delivery
JP4632687B2 (ja) *	2003-04-25	2011-02-16	ロート製薬株式会社	点鼻剤
JP5238779B2 (ja) *	2003-04-25	2013-07-17	ロート製薬株式会社	点鼻剤
US20050153946A1 (en) *	2003-12-24	2005-07-14	Collegium Pharmaceuticals, Inc.	Temperature-stable formulations, and methods of development thereof
GB0400804D0 (en)	2004-01-14	2004-02-18	Innoscience Technology Bv	Pharmaceutical compositions
US20060045850A1 (en) *	2004-08-30	2006-03-02	Qpharma, Llc	Nasal delivery of cyclodextrin complexes of anti-inflammatory steroids
EP2522365B1 (en)	2004-11-24	2016-10-26	Meda Pharmaceuticals Inc.	Compositions comprising azelastine and methods of use thereof
JP2009504767A (ja)	2005-08-17	2009-02-05	フレミング・アンド・カンパニー・ファーマシューティカルズ	ビタミンｂ１２鼻用スプレーおよび使用方法
KR100767976B1 (ko)	2006-08-25	2007-10-18	한국유나이티드제약 주식회사	비내 건조증에 효과적인 약제학적 조성물
US20080275030A1 (en)	2007-01-19	2008-11-06	Sveinbjorn Gizurarson	Methods and Compositions for the Delivery of a Therapeutic Agent
EP3150230A1 (en)	2007-01-19	2017-04-05	Hananja Ehf	Methods and compositions for the delivery of a therapeutic agent
JP2011001317A (ja) *	2009-06-19	2011-01-06	Fumakilla Ltd	鼻用洗浄剤
CN105188758A (zh) *	2013-03-15	2015-12-23	梅迪奇斯医药公司	氟尼缩松的局部组合物及治疗方法
US11135155B2 (en)	2014-07-08	2021-10-05	Hikma Pharmaceuticals Usa Inc.	Liquid naloxone spray
JP6097787B2 (ja) *	2015-06-09	2017-03-15	パルファーマシューティカル，インコーポレーテッド	鼻内送達用シアノコバラミン低粘度水性製剤
US11510859B2 (en)	2015-07-16	2022-11-29	Marinomed Biotech Ag	Method for improving aqueous solubility of water-insoluble or slightly water-soluble drugs
HUE053116T2 (hu)	2015-07-16	2021-06-28	Marinomed Biotech Ag	Eljárás vízben oldhatatlan vagy vízben rosszul oldódó hatóanyagok vízoldhatóságának javítására

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2989437A (en) *	1955-06-08	1961-06-20	Upjohn Co	Anti-inflammatory and anti-bacterial decongestant nasal spray compositions
MX3864E (es) *	1975-05-27	1981-08-26	Syntex Corp	Un proceso para prepara el compuesto cristalino 6-fluiro-11b 21-dihiroxi-16 17-isopropilidendioxipregna-1 4-dien-3 20-diona
DE2750090A1 (de) *	1976-11-19	1978-06-01	Sandoz Ag	Neue verabreichungsformen fuer organische verbindungen
US4444762A (en) *	1980-04-04	1984-04-24	Nelson Research & Development Company	Vehicle composition containing 1-substituted azacyclopentan-2-ones
US4344940A (en) *	1981-11-30	1982-08-17	E. R. Squibb & Sons, Inc.	Steroid formulation containing dipotassium EDTA
US4603131A (en) *	1982-04-26	1986-07-29	Bernstein Joel E	Method and composition for treating and preventing irritation of the mucous membranes of the nose

1986
- 1986-05-22 US US06/866,171 patent/US4782047A/en not_active Expired - Lifetime
1987
- 1987-05-21 AU AU73273/87A patent/AU609718B2/en not_active Ceased
- 1987-05-21 ES ES198787107416T patent/ES2031467T3/es not_active Expired - Lifetime
- 1987-05-21 KR KR1019870005032A patent/KR950008308B1/ko not_active Expired - Fee Related
- 1987-05-21 JP JP62126846A patent/JP2521291B2/ja not_active Expired - Lifetime
- 1987-05-21 EP EP87107416A patent/EP0246652B1/en not_active Expired - Lifetime
- 1987-05-21 IL IL82615A patent/IL82615A/xx not_active IP Right Cessation
- 1987-05-21 NZ NZ220394A patent/NZ220394A/en unknown
- 1987-05-21 NO NO872127A patent/NO173365C/no unknown
- 1987-05-21 FI FI872231A patent/FI88459C/fi not_active IP Right Cessation
- 1987-05-21 IT IT20621/87A patent/IT1205667B/it active
- 1987-05-21 AT AT87107416T patent/ATE65183T1/de not_active IP Right Cessation
- 1987-05-21 DK DK198702586A patent/DK175238B1/da active
- 1987-05-21 ZA ZA873663A patent/ZA873663B/xx unknown
- 1987-05-21 IE IE133587A patent/IE60259B1/en not_active IP Right Cessation
- 1987-05-21 CA CA000537690A patent/CA1288048C/en not_active Expired - Lifetime
- 1987-05-21 DE DE8787107416T patent/DE3771389D1/de not_active Expired - Lifetime
1991
- 1991-07-18 GR GR91400394T patent/GR3002317T3/el unknown
1994
- 1994-04-21 HK HK39094A patent/HK39094A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
AU609718B2 (en)	1991-05-09
FI872231A0 (fi)	1987-05-21
DK258687D0 (da)	1987-05-21
US4782047A (en)	1988-11-01
GR3002317T3 (en)	1992-12-30
NO872127L (no)	1987-11-23
EP0246652A2 (en)	1987-11-25
DK175238B1 (da)	2004-07-19
IE871335L (en)	1987-11-22
KR870010862A (ko)	1987-12-18
JP2521291B2 (ja)	1996-08-07
KR950008308B1 (ko)	1995-07-27
ZA873663B (en)	1988-12-28
IL82615A0 (en)	1987-11-30
ES2031467T3 (es)	1992-12-16
NO173365B (no)	1993-08-30
JPS62283927A (ja)	1987-12-09
ATE65183T1 (de)	1991-08-15
DK258687A (da)	1987-11-23
NZ220394A (en)	1990-04-26
IT1205667B (it)	1989-03-31
EP0246652B1 (en)	1991-07-17
EP0246652A3 (en)	1988-02-03
HK39094A (en)	1994-04-29
FI88459C (fi)	1993-05-25
DE3771389D1 (de)	1991-08-22
AU7327387A (en)	1987-11-26
FI872231L (fi)	1987-11-23
IE60259B1 (en)	1994-06-29
IL82615A (en)	1991-11-21
CA1288048C (en)	1991-08-27
IT8720621A0 (it)	1987-05-21
NO872127D0 (no)	1987-05-21
FI88459B (fi)	1993-02-15

Publication	Publication Date	Title
NO173365C (no)	1993-12-08	Fremgangsm}te for fremstilling av et i det vesentlige ikke-sviende, vandig, antiinflammatorisk steroidpreparat egnet for intranasal administerering
CY1120513T1 (el)	2019-07-10	Υψηλης συμπυκνωσης συνθεση μινοξιδιλης
AU618894B2 (en)	1992-01-09	Photoprotection compositions comprising sorbohydroxamic acid
ATE63220T1 (de)	1991-05-15	Transdermal resorbierbare, wasserhaltige zubereitungen von arylpropionsaeurederivaten und verfahren zur herstellung derselben.
DE3766200D1 (de)	1990-12-20	L-dopa enthaltendes arzneimittel.
DK581989D0 (da)	1989-11-20	Steroidlotion
IE791593L (en)	1980-03-05	Acid addition salts of dipiperidinoandrostanes
FI883338A0 (fi)	1988-07-13	Vattenloesningar av doxorubicinhydroklorid.
IE810891L (en)	1981-10-23	Topical formulation
AU1726183A (en)	1984-02-02	Ursolic acid derivatives
DE2963545D1 (en)	1982-10-07	Pharmaceutical composition containing all-e- or 13-z-7,8-dehydro-retinoic acid and process for its preparation
AU572689B2 (en)	1988-05-12	Pharmaceutical compositions of dezocine
FR2510577B1 (fr)	1986-04-11	Composes organiques azotes extraits de plantes et leurs derives, leur preparation et leurs utilisations therapeutiques, notamment en tant qu'agents antineoplastiques
EP0389773A3 (de)	1991-07-24	Verfahren zur Herstellung einer Galenischen Zubereitung mit optimaler Bioverfügbarkeit des Wirkstoffs 2-Hydroxy-5-methyllaurophenonoxime (HMLO)
ATE23161T1 (de)	1986-11-15	3-deazaguanin-sulfonsaeuresalze.
ATE87210T1 (de)	1993-04-15	Doxorubicin-loesungen.
DE3764457D1 (de)	1990-09-27	Empfaengnisverhuetende, waessrig-saure zusammensetzung und verfahren zu ihrer herstellung.