NO173785C - Analogifremgangsmaate for fremstilling av farmasoeytisk virksomme kinuklidinderivater samt mellom-produkt for fremstillingen - Google Patents

Analogifremgangsmaate for fremstilling av farmasoeytisk virksomme kinuklidinderivater samt mellom-produkt for fremstillingen

Info

Publication number
NO173785C
NO173785C NO861682A NO861682A NO173785C NO 173785 C NO173785 C NO 173785C NO 861682 A NO861682 A NO 861682A NO 861682 A NO861682 A NO 861682A NO 173785 C NO173785 C NO 173785C
Authority
NO
Norway
Prior art keywords
preparation
pharmaceutically effective
analogous procedure
quinuclidine derivatives
intermediate preparations
Prior art date
Application number
NO861682A
Other languages
English (en)
Norwegian (no)
Other versions
NO861682L (no
NO173785B (no
Inventor
Abraham Fisher
Ishai Karton
Eliahu Heldman
Aharon Levy
Yona Grundfeld
Original Assignee
Israel State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IL75166A external-priority patent/IL75166A/xx
Application filed by Israel State filed Critical Israel State
Publication of NO861682L publication Critical patent/NO861682L/no
Publication of NO173785B publication Critical patent/NO173785B/no
Publication of NO173785C publication Critical patent/NO173785C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO861682A 1985-05-10 1986-04-29 Analogifremgangsmaate for fremstilling av farmasoeytisk virksomme kinuklidinderivater samt mellom-produkt for fremstillingen NO173785C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL75166A IL75166A (en) 1985-05-10 1985-05-10 2-substituted spiro(1,3-oxathiolane-5,3-quinuclidine)derivatives,their preparation and pharmaceutical compositions containing them and 3-hydroxy-3-mercaptomethylquinuclidine as intermidiate therefor
IL7756886 1986-01-10

Publications (3)

Publication Number Publication Date
NO861682L NO861682L (no) 1986-11-11
NO173785B NO173785B (no) 1993-10-25
NO173785C true NO173785C (no) 1994-02-02

Family

ID=26321442

Family Applications (1)

Application Number Title Priority Date Filing Date
NO861682A NO173785C (no) 1985-05-10 1986-04-29 Analogifremgangsmaate for fremstilling av farmasoeytisk virksomme kinuklidinderivater samt mellom-produkt for fremstillingen

Country Status (9)

Country Link
US (1) US4855290A (da)
EP (1) EP0205247B1 (da)
JP (2) JPH0725767B2 (da)
AT (1) ATE83485T1 (da)
CA (1) CA1311479C (da)
DE (1) DE3687288T2 (da)
DK (1) DK173084B1 (da)
ES (1) ES8703461A1 (da)
NO (1) NO173785C (da)

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ATE122353T1 (de) * 1987-10-05 1995-05-15 Yamanouchi Pharma Co Ltd Heterozyklische spiroverbindungen und ihre herstellung.
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US4900830A (en) * 1987-10-28 1990-02-13 Israel Institute For Biological Research Process for labelling sulfur-containing compounds
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US5407938A (en) * 1990-04-10 1995-04-18 Israel Institute For Biological Research Certain 1-methyl-piperidine-4-spiro-4'-(1'-3'-oxazolines) and corresponding -(1',3' thiazolines)
US5534520A (en) * 1990-04-10 1996-07-09 Fisher; Abraham Spiro compounds containing five-membered rings
US5268687A (en) * 1990-07-30 1993-12-07 Spectrum Sciences B.V. Laser scanning apparatus
JP2761973B2 (ja) * 1990-08-28 1998-06-04 雪印乳業株式会社 粉砕容易なシス‐２‐メチルスピロ（１，３‐オキサチオラン‐５，３′）キヌクリジン塩酸塩１／２水和物の製造方法
JP2683783B2 (ja) * 1992-07-10 1997-12-03 雪印乳業株式会社 シェーグレン症候群治療剤
JPH06239861A (ja) * 1993-02-17 1994-08-30 Kanegafuchi Chem Ind Co Ltd 二環式含チッ素化合物
JP2983141B2 (ja) * 1993-10-06 1999-11-29 株式会社三和化学研究所 新規化合物及び該化合物を有効成分とする脳機能改善剤
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JP2852608B2 (ja) * 1994-06-27 1999-02-03 雪印乳業株式会社 口腔乾燥症治療剤
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US6528529B1 (en) 1998-03-31 2003-03-04 Acadia Pharmaceuticals Inc. Compounds with activity on muscarinic receptors
JP4447685B2 (ja) * 1999-01-14 2010-04-07 第一三共株式会社 皮膚乾燥症治療剤
WO2000047210A1 (en) * 1999-02-09 2000-08-17 Uab Research Foundation Use of 4-amino pyridine for treatment of peripheral neuropathies
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
US6433168B1 (en) 1999-07-26 2002-08-13 Sumika Fine Chemicals Co., Ltd. Highly pure phenothiazine compound, production method thereof, production method of intermediate therefor, and hydrate and novel crystal as starting materials for the intermediate
MXPA04010921A (es) * 2002-05-03 2005-05-27 Israel Inst Biolog Res Metodos y composiciones para el tratamietno de trastornos del sistema nervioso central y periferico y compuestos novedosos utiles para los mismos.
KR20060057569A (ko) * 2003-07-08 2006-05-26 아스트라제네카 아베 알파7 니코틴계 아세틸콜린 수용체와 친화도를 갖는스피로[1-아자비시클로[2.2.2]옥탄-3,5'-옥사졸리딘-2'-온] 유도체
US20050192321A1 (en) * 2003-09-15 2005-09-01 Meythaler Jay M. Treatment of neuropathy with rapid release aminopyridine
WO2006013914A1 (ja) * 2004-08-06 2006-02-09 Daiichi Pharmaceutical Co., Ltd. 口腔粘膜投与剤
US20080113983A1 (en) * 2004-12-15 2008-05-15 Astrazeneca Ab Nicotinic Acetylcholine Receptor Ligands
EP2258359A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis by muscarinic receptor modulation with sabcomelin
JP2009506069A (ja) * 2005-08-26 2009-02-12 ブレインセルス，インコーポレイティド ムスカリン性受容体調節による神経発生
JP2009512711A (ja) 2005-10-21 2009-03-26 ブレインセルス，インコーポレイティド Ｐｄｅ阻害による神経新生の調節
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KR20150116466A (ko) * 2009-01-26 2015-10-15 이스라엘 인스티튜트 포 바이올로지컬 리서치 이환형 헤테로사이클릭 스피로 화합물
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JP5452165B2 (ja) * 2009-10-23 2014-03-26 第一ファインケミカル株式会社 キヌクリジン類の製造法
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CN104892619A (zh) * 2015-06-26 2015-09-09 大道隆达（北京）医药科技发展有限公司 一种药物中间体的制备方法
US20180250270A1 (en) 2015-09-11 2018-09-06 Chase Pharmaceuticals Corporation Muscarinic combination and its use for combating hypocholinergic disorders of the central nervous system
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JP7163280B2 (ja) 2016-10-05 2022-10-31 エヌエスシー セラピューティクス ゲーエムベーハー ムスカリン性アセチルコリン受容体アゴニストの結晶性多形
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Also Published As

Publication number Publication date
EP0205247A3 (en) 1988-02-03
DK196686D0 (da) 1986-04-29
ES8703461A1 (es) 1987-03-01
CA1311479C (en) 1992-12-15
JPS61280497A (ja) 1986-12-11
DE3687288D1 (de) 1993-01-28
ATE83485T1 (de) 1993-01-15
NO861682L (no) 1986-11-11
JPH0725767B2 (ja) 1995-03-22
ES554280A0 (es) 1987-03-01
US4855290A (en) 1989-08-08
DK173084B1 (da) 1999-12-27
DK196686A (da) 1986-11-11
EP0205247B1 (en) 1992-12-16
JPH07223953A (ja) 1995-08-22
EP0205247A2 (en) 1986-12-17
NO173785B (no) 1993-10-25
DE3687288T2 (de) 1993-04-15

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