NO175003C - Fusjonsproteiner med eukaryotisk ballastandel, vektor som inneholder et DNA som koder for fusjonsproteinet samt E.coli celle inneholdene vektoren - Google Patents

Fusjonsproteiner med eukaryotisk ballastandel, vektor som inneholder et DNA som koder for fusjonsproteinet samt E.coli celle inneholdene vektoren

Info

Publication number: NO175003C
Authority: NO; Norway
Prior art keywords: vector; eukaryotic; well; fusion protein; dna encoding
Prior art date: 1985-12-21

Application number

NO865192A

Other languages

English (en)

Other versions

NO175003B (no

NO865192L (no

NO865192D0 (no

Inventor

Paul Habermann

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-12-21

Filing date

1986-12-19

Publication date

1994-08-17

1986-12-19 Application filed by Hoechst Ag filed Critical Hoechst Ag

1986-12-19 Publication of NO865192D0 publication Critical patent/NO865192D0/no

1987-06-22 Publication of NO865192L publication Critical patent/NO865192L/no

1994-05-09 Publication of NO175003B publication Critical patent/NO175003B/no

1994-08-17 Publication of NO175003C publication Critical patent/NO175003C/no

Links

102000037865 fusion proteins Human genes 0.000 title abstract 4
108020001507 fusion proteins Proteins 0.000 title abstract 4
241000588724 Escherichia coli Species 0.000 title 1
108010002350 Interleukin-2 Proteins 0.000 abstract 3
102000000588 Interleukin-2 Human genes 0.000 abstract 2
125000003275 alpha amino acid group Chemical group 0.000 abstract 1
150000001413 amino acids Chemical class 0.000 abstract 1
238000003776 cleavage reaction Methods 0.000 abstract 1
238000010276 construction Methods 0.000 abstract 1
230000007017 scission Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
- C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/55—IL-2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Engineering & Computer Science (AREA)
Toxicology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Wood Science & Technology (AREA)
Immunology (AREA)
Biotechnology (AREA)
Pharmacology & Pharmacy (AREA)
Microbiology (AREA)
Endocrinology (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Physics & Mathematics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Tropical Medicine & Parasitology (AREA)
Plant Pathology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Diabetes (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Sampling And Sample Adjustment (AREA)
Investigating Or Analysing Biological Materials (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

NO865192A 1985-12-21 1986-12-19 Fusjonsproteiner med eukaryotisk ballastandel, vektor som inneholder et DNA som koder for fusjonsproteinet samt E.coli celle inneholdene vektoren NO175003C (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE3545565		1985-12-21
DE19863636903 DE3636903A1 (de)	1985-12-21	1986-10-30	Fusionsproteine mit eukaryotischem ballastanteil

Publications (4)

Publication Number	Publication Date
NO865192D0 NO865192D0 (no)	1986-12-19
NO865192L NO865192L (no)	1987-06-22
NO175003B NO175003B (no)	1994-05-09
NO175003C true NO175003C (no)	1994-08-17

Family

ID=25839208

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO865192A NO175003C (no)	1985-12-21	1986-12-19	Fusjonsproteiner med eukaryotisk ballastandel, vektor som inneholder et DNA som koder for fusjonsproteinet samt E.coli celle inneholdene vektoren

Country Status (16)

Country	Link
EP (1)	EP0229998B1 (no)
JP (2)	JP2553058B2 (no)
KR (1)	KR950000301B1 (no)
AT (1)	ATE78296T1 (no)
AU (1)	AU599943B2 (no)
CA (1)	CA1339894C (no)
DE (1)	DE3636903A1 (no)
DK (1)	DK168823B1 (no)
ES (1)	ES2033678T3 (no)
FI (1)	FI93734C (no)
GR (1)	GR3005985T3 (no)
HU (1)	HU209747B (no)
IE (1)	IE58935B1 (no)
IL (1)	IL81018A (no)
NO (1)	NO175003C (no)
PT (1)	PT83973B (no)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3545568A1 (de) *	1985-12-21	1987-07-16	Hoechst Ag	Gm-csf-protein, seine derivate, herstellung solcher proteine und ihre verwendung
DE3844211A1 (de) *	1988-12-29	1990-07-05	Hoechst Ag	Neue insulinderivate, verfahren zu deren herstellung, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
FR2643646B1 (fr) *	1989-02-27	1993-09-17	Pasteur Institut	Expression de sequences de nucleotides codant pour des vesicules a gaz
CU22222A1 (es) *	1989-08-03	1995-01-31	Cigb	Procedimiento para la expresion de proteinas heterologicas producidas de forma fusionada en escherichia coli, su uso, vectores de expresion y cepas recombinantes
DE3942580A1 (de) *	1989-12-22	1991-06-27	Basf Ag	Verfahren zur herstellung von hirudin
DE4105480A1 (de) *	1991-02-21	1992-08-27	Boehringer Mannheim Gmbh	Verbesserte aktivierung von rekombinanten proteinen
DE59711533D1 (de)	1996-07-26	2004-05-27	Aventis Pharma Gmbh	Insulinderivate mit erhöhter Zinkbindung
DE19825447A1 (de)	1998-06-06	1999-12-09	Hoechst Marion Roussel De Gmbh	Neue Insulinanaloga mit erhöhter Zinkbildung
DE102006031955A1 (de)	2006-07-11	2008-01-17	Sanofi-Aventis Deutschland Gmbh	Verfahren zur Herstellung von Insulinanaloga mit dibasischem B-Kettenende
DE102006031962A1 (de)	2006-07-11	2008-01-17	Sanofi-Aventis Deutschland Gmbh	Amidiertes Insulin Glargin
PT3228320T (pt)	2008-10-17	2020-03-26	Sanofi Aventis Deutschland	Combinação de uma insulina e de um agonista do glp-1
KR101853606B1 (ko)	2009-07-06	2018-05-03	사노피-아벤티스 도이칠란트 게엠베하	메티오닌을 함유하는 수성 인슐린 제제
DK2498802T3 (en)	2009-11-13	2015-04-13	Sanofi Aventis Deutschland	Pharmaceutical composition comprising a GLP-1 agonist, insulin and a methionine
KR101337322B1 (ko)	2009-11-13	2013-12-06	사노피-아벤티스 도이칠란트 게엠베하	Ｇｌｐ-1 효능제 및 메티오닌을 포함하는 약제학적 조성물
ES2606554T3 (es)	2010-08-30	2017-03-24	Sanofi-Aventis Deutschland Gmbh	Uso de AVE0010 para la fabricación de un medicamento para el tratamiento de la diabetes mellitus de tipo 2
US9821032B2 (en)	2011-05-13	2017-11-21	Sanofi-Aventis Deutschland Gmbh	Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
PL2750699T3 (pl)	2011-08-29	2015-12-31	Sanofi Aventis Deutschland	Kombinacja farmaceutyczna do stosowania w kontroli glikemii u pacjentów z cukrzycą typu 2
AR087744A1 (es)	2011-09-01	2014-04-16	Sanofi Aventis Deutschland	Composicion farmaceutica para uso en el tratamiento de una enfermedad neurodegenerativa
AU2015359376B2 (en)	2014-12-12	2021-09-09	Sanofi-Aventis Deutschland Gmbh	Insulin glargine/lixisenatide fixed ratio formulation
TWI748945B (zh)	2015-03-13	2021-12-11	德商賽諾菲阿凡提斯德意志有限公司	第２型糖尿病病患治療
TW201705975A (zh)	2015-03-18	2017-02-16	賽諾菲阿凡提斯德意志有限公司	第２型糖尿病病患之治療
KR20200080748A (ko)	2018-12-27	2020-07-07	주식회사 폴루스	음이온 교환 크로마토그래피를 이용한 인슐린 전구체의 정제방법
KR20200080747A (ko)	2018-12-27	2020-07-07	주식회사 폴루스	인슐린 전구체의 인슐린 효소 전환용 조성물 및 이를 이용하여 인슐린 전구체를 인슐린으로 전환하는 방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK108685A (da) *	1984-03-19	1985-09-20	Fujisawa Pharmaceutical Co	Vaekstfaktor i
EP0158198A1 (en) *	1984-03-29	1985-10-16	Takeda Chemical Industries, Ltd.	DNA and use thereof
GB8412517D0 (en) *	1984-05-16	1984-06-20	Nagai K	Recombinant fusion proteins

1986
- 1986-10-30 DE DE19863636903 patent/DE3636903A1/de not_active Withdrawn
- 1986-12-16 AT AT86117481T patent/ATE78296T1/de not_active IP Right Cessation
- 1986-12-16 EP EP86117481A patent/EP0229998B1/de not_active Expired - Lifetime
- 1986-12-16 ES ES198686117481T patent/ES2033678T3/es not_active Expired - Lifetime
- 1986-12-18 FI FI865187A patent/FI93734C/fi not_active IP Right Cessation
- 1986-12-18 IL IL81018A patent/IL81018A/xx not_active IP Right Cessation
- 1986-12-19 PT PT83973A patent/PT83973B/pt unknown
- 1986-12-19 NO NO865192A patent/NO175003C/no not_active IP Right Cessation
- 1986-12-19 DK DK619186A patent/DK168823B1/da not_active IP Right Cessation
- 1986-12-19 HU HU865354A patent/HU209747B/hu unknown
- 1986-12-19 CA CA000525858A patent/CA1339894C/en not_active Expired - Lifetime
- 1986-12-19 IE IE333486A patent/IE58935B1/en not_active IP Right Cessation
- 1986-12-19 AU AU66760/86A patent/AU599943B2/en not_active Expired
- 1986-12-20 KR KR1019860011010A patent/KR950000301B1/ko not_active Expired - Lifetime
- 1986-12-22 JP JP61306185A patent/JP2553058B2/ja not_active Expired - Lifetime
1992
- 1992-10-15 GR GR920402187T patent/GR3005985T3/el unknown
1995
- 1995-10-11 JP JP7263310A patent/JP2774260B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
NO175003B (no)	1994-05-09
JPH08187089A (ja)	1996-07-23
KR950000301B1 (ko)	1995-01-13
DK168823B1 (da)	1994-06-20
IL81018A (en)	1992-03-29
EP0229998A2 (de)	1987-07-29
AU599943B2 (en)	1990-08-02
ES2033678T3 (es)	1993-04-01
GR3005985T3 (no)	1993-06-07
DE3636903A1 (de)	1987-07-02
HU209747B (en)	1994-10-28
JP2774260B2 (ja)	1998-07-09
PT83973A (de)	1987-01-01
AU6676086A (en)	1987-06-25
KR870006187A (ko)	1987-07-09
CA1339894C (en)	1998-06-02
DK619186A (da)	1987-06-22
NO865192L (no)	1987-06-22
JP2553058B2 (ja)	1996-11-13
ATE78296T1 (de)	1992-08-15
IE863334L (en)	1987-06-21
FI93734B (fi)	1995-02-15
FI865187A0 (fi)	1986-12-18
EP0229998A3 (en)	1988-08-03
HUT44614A (en)	1988-03-28
NO865192D0 (no)	1986-12-19
FI93734C (fi)	1995-05-26
EP0229998B1 (de)	1992-07-15
DK619186D0 (da)	1986-12-19
FI865187L (fi)	1987-06-22
IL81018A0 (en)	1987-03-31
IE58935B1 (en)	1993-12-01
JPS62167799A (ja)	1987-07-24
PT83973B (pt)	1989-07-31

Legal Events

Date	Code	Title	Description
2007-05-07	MK1K	Patent expired

Publication	Publication Date	Title
AU599943B2 (en)	1990-08-02	Fusion proteins with a eukaryotic ballast portion
NO175640C (no)	1994-11-09	Fusjonsproteiner og DNA som koder for disse
DK371087D0 (da)	1987-07-16	Mamalialt interleukin-4
BG60107B2 (bg)	1993-10-29	Метод за получаване на еукариотен полипептид
DK164940C (da)	1993-02-01	Polypeptid med human-gamma-interferonaktivitet, genteknologisk fremgangsmaade til fremstilling deraf, hybrid-plasmider indeholdende en dna-sekvens, der koder for peptidet, vaertsorganismer indeholdende hybridplasmiderne, samt laegemidler, som indeholder polypeptidet
ATE89317T1 (de)	1993-05-15	Proteine, expressionsvektoren, die fuer solche proteine kodierende dna enthalten und zellen, die solche expressionsvektoren enthalten.
GR3020035T3 (en)	1996-08-31	Mammalian cell derived autonomously replicating sequence DNA fragments having affinity to DNA binding proteins
ATE78873T1 (de)	1992-08-15	Verfahren zur selektiven spaltung von fusionsproteinen.