NO175871B - - Google Patents

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Publication number: NO175871B
Authority: NO; Norway
Prior art keywords: yeast; dna; fragment; promoter; gene
Prior art date: 1985-08-29

Application number

NO863458A

Other languages

English (en)

Norwegian (no)

Other versions

NO863458L (no

NO863458D0 (no

NO175871C (no

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-08-29

Filing date

1986-08-28

Publication date

1994-09-12

1986-08-28 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1986-08-28 Publication of NO863458D0 publication Critical patent/NO863458D0/no

1987-03-02 Publication of NO863458L publication Critical patent/NO863458L/no

1994-09-12 Publication of NO175871B publication Critical patent/NO175871B/no

1994-12-21 Publication of NO175871C publication Critical patent/NO175871C/no

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Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6456—Plasminogen activators
- C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21069—Protein C activated (3.4.21.69)

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Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Biomedical Technology (AREA)
Microbiology (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
Mycology (AREA)
Gastroenterology & Hepatology (AREA)
Toxicology (AREA)
Physics & Mathematics (AREA)
Plant Pathology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Tropical Medicine & Parasitology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Alcoholic Beverages (AREA)
Coloring Foods And Improving Nutritive Qualities (AREA)
Enzymes And Modification Thereof (AREA)
Led Devices (AREA)
Gyroscopes (AREA)
Graft Or Block Polymers (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Distillation Of Fermentation Liquor, Processing Of Alcohols, Vinegar And Beer (AREA)

NO863458A 1985-08-29 1986-08-28 Gjærhybridpromotor, gjærhybridvektor, Saccharomyces spec.-vert, samt fremgangsmåte for fremstilling av et polypeptid heterologt med gjær NO175871C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB858521496A GB8521496D0 (en)	1985-08-29	1985-08-29	Repressible yeast promoters

Publications (4)

Publication Number	Publication Date
NO863458D0 NO863458D0 (no)	1986-08-28
NO863458L NO863458L (no)	1987-03-02
NO175871B true NO175871B (fr)	1994-09-12
NO175871C NO175871C (no)	1994-12-21

Family

ID=10584428

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO863458A NO175871C (no)	1985-08-29	1986-08-28	Gjærhybridpromotor, gjærhybridvektor, Saccharomyces spec.-vert, samt fremgangsmåte for fremstilling av et polypeptid heterologt med gjær

Country Status (22)

Country	Link
US (1)	US5436136A (fr)
EP (1)	EP0213593B1 (fr)
JP (1)	JPH07110233B2 (fr)
AT (1)	ATE62510T1 (fr)
AU (1)	AU599329B2 (fr)
CA (1)	CA1318616C (fr)
DD (2)	DD254212A5 (fr)
DE (1)	DE3678647D1 (fr)
DK (1)	DK175093B1 (fr)
ES (3)	ES2001618A6 (fr)
FI (1)	FI91280C (fr)
GB (1)	GB8521496D0 (fr)
GR (1)	GR862209B (fr)
HU (1)	HU211207B (fr)
IE (1)	IE58844B1 (fr)
IL (1)	IL79837A (fr)
NO (1)	NO175871C (fr)
NZ (1)	NZ217388A (fr)
PH (1)	PH24715A (fr)
PT (1)	PT83273B (fr)
SU (1)	SU1630616A3 (fr)
ZA (1)	ZA866535B (fr)

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EP0245479B1 (fr) *	1985-11-13	1993-02-17	Xoma Corporation	Promoteur de kinase de phosphoglycerate raccourci
MY101203A (en) *	1985-12-12	1991-08-17	Ucp Gen Pharma Ag	Production of thrombin iinhibitors.
GB8530631D0 (en)	1985-12-12	1986-01-22	Ciba Geigy Ag	Thrombin inhibitors
GB8620926D0 (en) *	1986-08-29	1986-10-08	Delta Biotechnology Ltd	Yeast promoter
GB8907110D0 (en) *	1988-05-04	1989-05-10	Ciba Geigy Ag	Improvements in the production of polypeptides
NO177065C (no) *	1988-09-26	1995-07-12	Labofina Sa	Framgangsmåte for framstilling av enzymatisk aktivt humant lysozym
US5612198A (en) *	1990-09-04	1997-03-18	The Salk Institute	Production of insulin-like growth factor-1 in methylotrophic yeast cells
EP0548267A4 (en) *	1990-09-04	1994-11-23	Salk Inst Biotech Ind	Production of insulin-like growth factor-1 in methylotrophic yeast cells
ATE220105T1 (de) *	1991-04-01	2002-07-15	Merck & Co Inc	Gene, die die proteolytische aktivitaet von pichia beeinflussen und deren verwendung
US5674728A (en) *	1993-11-03	1997-10-07	Novartis Corporation	Aspergillus niger vacuolar aspartyl protease
JPH08173170A (ja) *	1994-05-25	1996-07-09	Kirin Brewery Co Ltd	キャンディダ・ユティリス酵母の形質転換系、およびそれによる異種遺伝子の発現
DE69731960T2 (de) *	1996-09-24	2005-12-15	Cadus Pharmaceutical Corp.	Verfahren und zusammensetzungen für die identifizierung von receptor effectoren
US6265186B1 (en)	1997-04-11	2001-07-24	Dsm N.V.	Yeast cells comprising at least two copies of a desired gene integrated into the chromosomal genome at more than one non-ribosomal RNA encoding domain, particularly with Kluyveromyces
US6890730B1 (en)	1999-12-10	2005-05-10	The Salk Institute	Sequence and method for increasing protein expression in cellular expression systems
US8008459B2 (en) *	2001-01-25	2011-08-30	Evolva Sa	Concatemers of differentially expressed multiple genes
WO2011146833A1 (fr)	2010-05-20	2011-11-24	Evolva Inc.	Procédé de fabrication de composés isoprénoïdes dans une levure
KR20220047395A (ko)	2012-03-09	2022-04-15	베스타론 코포레이션	독성 펩타이드 제조, 식물에서의 펩타이드 발현 및 시스테인 농후 펩타이드의 조합
WO2021216621A2 (fr)	2020-04-20	2021-10-28	Vestaron Corporation	Polypeptides variants d'u1-agatoxine-ta1b stables à la protéolyse pour la lutte antiparasitaire
MX2022013415A (es)	2020-05-01	2022-11-14	Vestaron Corp	Combinaciones de insecticidas.
CA3215602A1 (fr)	2021-04-01	2022-10-06	Vestaron Corporation	Polypeptides mutants av3 destines a la lutte antiparasitaire
WO2023122805A1 (fr)	2021-12-20	2023-06-29	Vestaron Corporation	Procédé de pression de sélection par sorbitol
TW202413392A (zh)	2022-05-18	2024-04-01	美商韋斯塔隆公司	殺蟲ａｃｔｘ肽變異體
WO2023245100A1 (fr)	2022-06-17	2023-12-21	Vestaron Corporation	Peptides variants de ncr13 antimicrobiens
WO2024026406A2 (fr)	2022-07-29	2024-02-01	Vestaron Corporation	Peptides actx de nouvelle génération
WO2024259306A2 (fr)	2023-06-16	2024-12-19	Vestaron Corporation	Polypeptides variants pvd1 pour la lutte contre les nuisibles
WO2025226701A1 (fr)	2024-04-23	2025-10-30	Vestaron Corporation	Polypeptides variants de u1-agatoxine-ta1b stables à la protéolyse pour lutte antiparasitaire

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Publication number	Priority date	Publication date	Assignee	Title
GB2125047B (en) *	1982-08-09	1986-02-19	Ciba Geigy Ag	Yeast hybrid vectors and their use for the production of polypeptides
AU577259B2 (en) *	1982-08-13	1988-09-22	Zymogenetics Inc.	Glycolytic promters for regulated protein expression protease inhibitor
US4876197A (en) *	1983-02-22	1989-10-24	Chiron Corporation	Eukaryotic regulatable transcription
NZ207926A (en) *	1983-04-25	1988-04-29	Genentech Inc	Use of yeast #a#-factor to assist in expression of proteins heterologus to yeast
IE58011B1 (en) *	1983-05-27	1993-06-16	Texas A & M Univ Sys	Method for producing a recombinant baculovirus expression vector
GB8314961D0 (en) *	1983-05-31	1983-07-06	Kingsman A J	Dna sequence
PH22337A (en) *	1983-11-21	1988-08-12	Ciba Geigy Ag	Synthesis of fibrinolytic agents by yeast
DE3587759T2 (de) *	1984-05-11	1994-07-07	Chiron Corp., Emeryville, Calif.	Erhöhte Hefetranskription unter Verwendung einer Hybridkonstruktion der Promotorregion.
EP0164566A3 (fr) *	1984-05-11	1986-10-29	LGA Gastechnik GmbH	Dispositif de sécurité pour réservoirs de gaz liquéfié
US4895800A (en) *	1985-11-26	1990-01-23	Phillips Petroleum Company	Yeast production of hepatitis B surface antigen

1985
- 1985-08-29 GB GB858521496A patent/GB8521496D0/en active Pending
1986
- 1986-08-25 IL IL79837A patent/IL79837A/xx not_active IP Right Cessation
- 1986-08-25 FI FI863430A patent/FI91280C/fi not_active IP Right Cessation
- 1986-08-26 EP EP86111820A patent/EP0213593B1/fr not_active Expired - Lifetime
- 1986-08-26 DE DE8686111820T patent/DE3678647D1/de not_active Expired - Lifetime
- 1986-08-26 AT AT86111820T patent/ATE62510T1/de not_active IP Right Cessation
- 1986-08-27 DD DD29389486A patent/DD254212A5/de not_active IP Right Cessation
- 1986-08-27 GR GR862209A patent/GR862209B/el unknown
- 1986-08-27 CA CA000516879A patent/CA1318616C/fr not_active Expired - Lifetime
- 1986-08-27 DD DD31325586A patent/DD267739A5/de unknown
- 1986-08-28 PT PT83273A patent/PT83273B/pt unknown
- 1986-08-28 DK DK198604096A patent/DK175093B1/da not_active IP Right Cessation
- 1986-08-28 AU AU62032/86A patent/AU599329B2/en not_active Expired
- 1986-08-28 PH PH34192A patent/PH24715A/en unknown
- 1986-08-28 IE IE230786A patent/IE58844B1/en not_active IP Right Cessation
- 1986-08-28 NZ NZ217388A patent/NZ217388A/xx unknown
- 1986-08-28 SU SU864028035A patent/SU1630616A3/ru active
- 1986-08-28 ZA ZA866535A patent/ZA866535B/xx unknown
- 1986-08-28 HU HU863720A patent/HU211207B/hu unknown
- 1986-08-28 NO NO863458A patent/NO175871C/no not_active IP Right Cessation
- 1986-08-29 JP JP61201924A patent/JPH07110233B2/ja not_active Expired - Lifetime
- 1986-08-29 ES ES8601490A patent/ES2001618A6/es not_active Expired
1988
- 1988-03-16 ES ES8800794A patent/ES2006382A6/es not_active Expired
- 1988-03-16 ES ES8800795A patent/ES2006383A6/es not_active Expired
1991
- 1991-12-20 US US07/811,898 patent/US5436136A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
SU1630616A3 (ru)	1991-02-23
AU6203286A (en)	1987-03-05
HU211207B (en)	1995-11-28
GB8521496D0 (en)	1985-10-02
EP0213593B1 (fr)	1991-04-10
ES2001618A6 (es)	1988-06-01
AU599329B2 (en)	1990-07-19
JPS6251995A (ja)	1987-03-06
NZ217388A (en)	1989-02-24
GR862209B (en)	1986-12-31
IL79837A (en)	1992-06-21
DE3678647D1 (en)	1991-05-16
JPH07110233B2 (ja)	1995-11-29
US5436136A (en)	1995-07-25
EP0213593A1 (fr)	1987-03-11
PT83273A (en)	1986-09-01
DK409686D0 (da)	1986-08-28
ATE62510T1 (de)	1991-04-15
IE58844B1 (en)	1993-11-17
PH24715A (en)	1990-10-01
IL79837A0 (en)	1986-11-30
CA1318616C (fr)	1993-06-01
PT83273B (pt)	1989-05-12
DD254212A5 (de)	1988-02-17
DD267739A5 (de)	1989-05-10
ES2006383A6 (es)	1989-04-16
FI91280C (fi)	1994-06-10
FI91280B (fi)	1994-02-28
NO863458L (no)	1987-03-02
DK175093B1 (da)	2004-05-24
DK409686A (da)	1987-03-01
FI863430L (fi)	1987-03-01
IE862307L (en)	1987-02-28
ZA866535B (en)	1987-04-29
NO863458D0 (no)	1986-08-28
NO175871C (no)	1994-12-21
FI863430A0 (fi)	1986-08-25
HUT42525A (en)	1987-07-28
ES2006382A6 (es)	1989-04-16

Legal Events

Date	Code	Title	Description
2006-10-09	MK1K	Patent expired

Publication	Publication Date	Title
NO175871B (fr)	1994-09-12
EP0100561B1 (fr)	1989-05-31	Vecteurs hybrides de levure et leur utilisation pour la production des polypeptides
EP0123544A2 (fr)	1984-10-31	Procédé d'expression de protéines hétérologues dans les levures, vecteurs d'expression et micro-organismes du genre levure à cet effet
US5102789A (en)	1992-04-07	Production of epideramal growth factor in pichia pastoris yeast cells
EP0088632B1 (fr)	1993-06-16	Expression, traitement et excrétion de protéine hétérologue par des levures
KR102699074B1 (ko)	2024-08-26	재조합 숙주 세포에서 탄소 공급원 조절된 단백질 생산
Chang et al.	1986	Saccharomyces cerevisiae secretes and correctly processes human interferon hybrid proteins containing yeast invertase signal peptides
CZ284251B6 (cs)	1998-10-14	Způsob výroby heterologního proteinu v transformované buňce
NO178035B (no)	1995-10-02	Ekspressjonsvektor, gjærcelle som er i stand til å utskille desulfatohirudin samt fremgangsmåte for fremstilling av et terapeutisk aktivt desulfatohirudin
JPS6236183A (ja)	1987-02-17	サツカロミセス・セレビシエからのポリペプチドの発現および分泌
US5939287A (en)	1999-08-17	Method for production of proteins in yeast
US7198919B1 (en)	2007-04-03	Use of alpha factor sequences in yeast expression systems
EP0264118B1 (fr)	1993-08-04	Méthode de préparation de protéines
Goodey et al.	1987	Expression and secretion of foreign polypeptides in yeast
KR940011534B1 (ko)	1994-12-20	억제성 효모 프로모터의 제조방법
Skipper	1987	ENCODED IN THE M₁ DOUBLE-STRANDED RNA OF YEAST
HK40054115A (en)	2022-02-18	Carbon-source regulated protein production in a recombinant host cell
PH26266A (en)	1992-04-01	Yeast hybrid vectors and their use for the production of polypeptides