NO177138C - Analogifremgangsmåte ved fremstilling av substituerte imidazolderivater - Google Patents

Analogifremgangsmåte ved fremstilling av substituerte imidazolderivater

Info

Publication number
NO177138C
NO177138C NO894563A NO894563A NO177138C NO 177138 C NO177138 C NO 177138C NO 894563 A NO894563 A NO 894563A NO 894563 A NO894563 A NO 894563A NO 177138 C NO177138 C NO 177138C
Authority
NO
Norway
Prior art keywords
preparation
imidazole derivatives
analogous procedure
substituted imidazole
hal
Prior art date
Application number
NO894563A
Other languages
English (en)
Norwegian (no)
Other versions
NO894563D0 (no
NO894563L (no
NO177138B (no
Inventor
Arto Johannes Karjalainen
Raimo Einari Virtanen
Arja Leena Karjalainen
Original Assignee
Farmos Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmos Oy filed Critical Farmos Oy
Publication of NO894563D0 publication Critical patent/NO894563D0/no
Publication of NO894563L publication Critical patent/NO894563L/no
Publication of NO177138B publication Critical patent/NO177138B/no
Publication of NO177138C publication Critical patent/NO177138C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/58—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/06—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO894563A 1988-12-09 1989-11-16 Analogifremgangsmåte ved fremstilling av substituerte imidazolderivater NO177138C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8828831A GB2225782A (en) 1988-12-09 1988-12-09 Imidazole derivatives useful for treatment of diabetes

Publications (4)

Publication Number Publication Date
NO894563D0 NO894563D0 (no) 1989-11-16
NO894563L NO894563L (no) 1990-06-11
NO177138B NO177138B (no) 1995-04-18
NO177138C true NO177138C (no) 1995-07-26

Family

ID=10648267

Family Applications (1)

Application Number Title Priority Date Filing Date
NO894563A NO177138C (no) 1988-12-09 1989-11-16 Analogifremgangsmåte ved fremstilling av substituerte imidazolderivater

Country Status (22)

Country Link
US (1) US5292887A (de)
EP (1) EP0372954B1 (de)
JP (1) JP2868813B2 (de)
KR (1) KR900009605A (de)
CN (1) CN1023219C (de)
AT (1) ATE102608T1 (de)
AU (1) AU619928B2 (de)
CA (1) CA2004799A1 (de)
DD (1) DD290880A5 (de)
DE (1) DE68913673T2 (de)
DK (1) DK603789A (de)
ES (1) ES2052937T3 (de)
FI (1) FI96026C (de)
GB (1) GB2225782A (de)
HU (1) HU205086B (de)
IE (1) IE61870B1 (de)
IL (1) IL92609A0 (de)
NO (1) NO177138C (de)
NZ (1) NZ231649A (de)
PT (1) PT92515B (de)
RU (2) RU1831479C (de)
ZA (1) ZA899366B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI862039A0 (fi) * 1986-05-15 1986-05-15 Farmos Oy Nytt foerfarande foer framstaellning av 4(5)-substituerade imidazolderivat.
GB9127050D0 (en) * 1991-12-20 1992-02-19 Orion Yhtymae Oy Substituted imidazole derivatives and their preparation and use
GB9312669D0 (en) 1993-06-18 1993-08-04 Orion Yhtymae Oy New opticla isomers
FR2735776B1 (fr) * 1995-06-22 1997-07-18 Synthelabo Derives de 2,3-dihydro-1h-indole, leur preparation et leur application en therapeutique
GB9520150D0 (en) * 1995-10-03 1995-12-06 Orion Yhtymae Oy New imidazole derivatives
WO2000042023A1 (en) * 1999-01-18 2000-07-20 Novo Nordisk A/S Substituted imidazoles, their preparation and use
US6388090B2 (en) 2000-01-14 2002-05-14 Orion Corporation Imidazole derivatives
FI20000073A0 (fi) * 2000-01-14 2000-01-14 Orion Yhtymae Oy Uusia imidatsolijohdannaisia
AU2001258469B2 (en) 2000-05-08 2005-04-14 Orion Corporation New polycyclic indanylimidazoles with alpha2 adrenergic activity
FR2839719B1 (fr) * 2002-05-16 2004-08-06 Pf Medicament Nouveaux composes imidazoliques, leur procede de preparation et leur utilisation a titre de medicaments
US8188126B2 (en) 2002-05-16 2012-05-29 Pierre Fabre Medicament Imidazolic compounds and use thereof as alpha-2 adrenergic receptors
GB0226076D0 (en) * 2002-11-08 2002-12-18 Rp Scherer Technologies Inc Improved formulations containing substituted imidazole derivatives
CN117186010B (zh) * 2023-08-15 2026-04-14 厦门欧瑞捷生物科技有限公司 一种盐酸阿替美唑的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2167408B (en) * 1984-11-23 1988-05-25 Farmos Oy Substituted imidazole derivatives and their preparation and use
FI81092C (fi) * 1986-05-15 1990-09-10 Farmos Oy Foerfarande foer framstaellning av terapeutiskt aktiva 4(5)-(2,3-dihydro-1h-inden-2-yl)-imidazolderivat.

Also Published As

Publication number Publication date
NO894563D0 (no) 1989-11-16
DK603789D0 (da) 1989-11-30
GB2225782A (en) 1990-06-13
NO894563L (no) 1990-06-11
HU205086B (en) 1992-03-30
ZA899366B (en) 1991-03-27
DK603789A (da) 1990-06-10
PT92515B (pt) 1995-08-09
JPH02202874A (ja) 1990-08-10
CN1043128A (zh) 1990-06-20
AU619928B2 (en) 1992-02-06
CA2004799A1 (en) 1990-06-09
FI96026B (fi) 1996-01-15
CN1023219C (zh) 1993-12-22
DE68913673T2 (de) 1994-07-14
DE68913673D1 (de) 1994-04-14
NO177138B (no) 1995-04-18
EP0372954B1 (de) 1994-03-09
JP2868813B2 (ja) 1999-03-10
FI96026C (fi) 1996-04-25
US5292887A (en) 1994-03-08
KR900009605A (ko) 1990-07-05
EP0372954A1 (de) 1990-06-13
NZ231649A (en) 1991-09-25
RU1833375C (en) 1993-08-07
RU1831479C (ru) 1993-07-30
IE893926L (en) 1990-06-09
IE61870B1 (en) 1994-11-30
GB8828831D0 (en) 1989-01-18
AU4599289A (en) 1990-08-16
ES2052937T3 (es) 1994-07-16
HUT52065A (en) 1990-06-28
FI895325A0 (fi) 1989-11-09
PT92515A (pt) 1990-06-29
DD290880A5 (de) 1991-06-13
ATE102608T1 (de) 1994-03-15
IL92609A0 (en) 1990-08-31

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