NO177675C - Analogifremgangsmåte for fremstilling av terapeutisk aktive P-substituerte propan-fosfinsyre forbindelser - Google Patents

Analogifremgangsmåte for fremstilling av terapeutisk aktive P-substituerte propan-fosfinsyre forbindelser

Info

Publication number: NO177675C
Authority: NO; Norway
Prior art keywords: hydrogen; hydroxy; group; preparation; aliphatic
Prior art date: 1989-06-03

Application number

NO902449A

Other languages

English (en)

Norwegian (no)

Other versions

NO177675B (no

NO902449L (no

NO902449D0 (no

Inventor

Stuart J Mickel

Georg Von Sprecher

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-06-03

Filing date

1990-06-01

Publication date

1995-11-01

1990-06-01 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1990-06-01 Publication of NO902449D0 publication Critical patent/NO902449D0/no

1990-12-04 Publication of NO902449L publication Critical patent/NO902449L/no

1995-07-24 Publication of NO177675B publication Critical patent/NO177675B/no

1995-11-01 Publication of NO177675C publication Critical patent/NO177675C/no

Links

UQZPTVULCJDKIV-UHFFFAOYSA-N CCC.O[PH2]=O Chemical class CCC.O[PH2]=O UQZPTVULCJDKIV-UHFFFAOYSA-N 0.000 title 1
229910052739 hydrogen Inorganic materials 0.000 abstract 6
239000001257 hydrogen Substances 0.000 abstract 6
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 4
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
125000001931 aliphatic group Chemical group 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical group 0.000 abstract 2
150000002431 hydrogen Chemical class 0.000 abstract 2
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
125000003277 amino group Chemical group 0.000 abstract 1
239000000935 antidepressant agent Substances 0.000 abstract 1
229940005513 antidepressants Drugs 0.000 abstract 1
239000002249 anxiolytic agent Substances 0.000 abstract 1
230000000949 anxiolytic effect Effects 0.000 abstract 1
229940005530 anxiolytics Drugs 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000000470 constituent Substances 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
239000002664 nootropic agent Substances 0.000 abstract 1
230000001777 nootropic effect Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
- C07F9/36—Amides thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
- C07F9/301—Acyclic saturated acids which can have further substituents on alkyl
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Neurology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Cephalosporin Compounds (AREA)

NO902449A 1989-06-03 1990-06-01 Analogifremgangsmåte for fremstilling av terapeutisk aktive P-substituerte propan-fosfinsyre forbindelser NO177675C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB898912814A GB8912814D0 (en)	1989-06-03	1989-06-03	P-substituted propane-phospinic acid compounds

Publications (4)

Publication Number	Publication Date
NO902449D0 NO902449D0 (no)	1990-06-01
NO902449L NO902449L (no)	1990-12-04
NO177675B NO177675B (no)	1995-07-24
NO177675C true NO177675C (no)	1995-11-01

Family

ID=10657847

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO902449A NO177675C (no)	1989-06-03	1990-06-01	Analogifremgangsmåte for fremstilling av terapeutisk aktive P-substituerte propan-fosfinsyre forbindelser

Country Status (21)

Country	Link
EP (1)	EP0402312B1 (de)
JP (1)	JPH0320288A (de)
KR (1)	KR910000766A (de)
AT (1)	ATE117693T1 (de)
AU (1)	AU633577B2 (de)
CA (1)	CA2018036A1 (de)
DD (1)	DD294945A5 (de)
DE (1)	DE69016270T2 (de)
DK (1)	DK0402312T3 (de)
ES (1)	ES2067717T3 (de)
FI (1)	FI95263C (de)
GB (1)	GB8912814D0 (de)
HU (1)	HU207335B (de)
IE (1)	IE65155B1 (de)
IL (1)	IL94537A (de)
MX (1)	MX20962A (de)
NO (1)	NO177675C (de)
NZ (1)	NZ233915A (de)
PT (1)	PT94244B (de)
YU (1)	YU106890A (de)
ZA (1)	ZA904203B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8728483D0 (en) *	1987-12-04	1988-01-13	Ciba Geigy Ag	Chemical compounds
EP0767174A1 (de) *	1991-11-21	1997-04-09	Ciba-Geigy Ag	Neue Aminoalkanphosphinsäuren und ihre Salze
DE19604195C1 (de) *	1996-02-06	1997-04-17	Hoechst Ag	Verfahren zur Herstellung von Phosphonigsäuremonoalkylestern
SK662001A3 (en)	1998-07-15	2001-10-08	Hassan Jomaa	Phosphorous organic compounds and their use
SE0102055D0 (sv) *	2001-06-08	2001-06-08	Astrazeneca Ab	New Compounds
DE102008056341A1 (de) *	2008-11-07	2010-05-12	Clariant International Limited	Verfahren zur Herstellung von monoaminofunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Acrylnitrilen und ihre Verwendung

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2032712C3 (de) *	1970-07-02	1978-10-19	Bayer Ag, 5090 Leverkusen	Verfahren zur Herstellung von w-Amino-alkanphosphonsäure bzw.- phosphinsäurederivaten
GB8728483D0 (en) *	1987-12-04	1988-01-13	Ciba Geigy Ag	Chemical compounds
GB8820266D0 (en) *	1988-08-26	1988-09-28	Smith Kline French Lab	Compounds

1989
- 1989-06-03 GB GB898912814A patent/GB8912814D0/en active Pending
1990
- 1990-05-25 EP EP90810387A patent/EP0402312B1/de not_active Expired - Lifetime
- 1990-05-25 DK DK90810387.2T patent/DK0402312T3/da active
- 1990-05-25 ES ES90810387T patent/ES2067717T3/es not_active Expired - Lifetime
- 1990-05-25 AT AT90810387T patent/ATE117693T1/de active
- 1990-05-25 DE DE69016270T patent/DE69016270T2/de not_active Expired - Fee Related
- 1990-05-28 IL IL9453790A patent/IL94537A/en unknown
- 1990-05-31 YU YU106890A patent/YU106890A/sh unknown
- 1990-05-31 AU AU56161/90A patent/AU633577B2/en not_active Ceased
- 1990-05-31 MX MX2096290A patent/MX20962A/es unknown
- 1990-05-31 DD DD90341208A patent/DD294945A5/de not_active IP Right Cessation
- 1990-06-01 ZA ZA904203A patent/ZA904203B/xx unknown
- 1990-06-01 FI FI902749A patent/FI95263C/fi not_active IP Right Cessation
- 1990-06-01 CA CA002018036A patent/CA2018036A1/en not_active Abandoned
- 1990-06-01 NZ NZ233915A patent/NZ233915A/en unknown
- 1990-06-01 NO NO902449A patent/NO177675C/no unknown
- 1990-06-01 IE IE198090A patent/IE65155B1/en not_active IP Right Cessation
- 1990-06-01 PT PT94244A patent/PT94244B/pt not_active IP Right Cessation
- 1990-06-01 HU HU903299A patent/HU207335B/hu not_active IP Right Cessation
- 1990-06-02 KR KR1019900008137A patent/KR910000766A/ko not_active Ceased
- 1990-06-04 JP JP2144591A patent/JPH0320288A/ja active Pending

Also Published As

Publication number	Publication date
IL94537A (en)	1994-11-28
DE69016270D1 (de)	1995-03-09
HU903299D0 (en)	1990-10-28
AU5616190A (en)	1990-12-06
MX20962A (es)	1994-02-28
IE901980L (en)	1990-12-03
DK0402312T3 (da)	1995-02-27
IE65155B1 (en)	1995-10-04
FI95263C (fi)	1996-01-10
DE69016270T2 (de)	1995-06-08
EP0402312A2 (de)	1990-12-12
AU633577B2 (en)	1993-02-04
FI95263B (fi)	1995-09-29
JPH0320288A (ja)	1991-01-29
PT94244B (pt)	1997-03-31
NZ233915A (en)	1992-07-28
PT94244A (pt)	1991-02-08
ZA904203B (en)	1991-02-27
NO177675B (no)	1995-07-24
CA2018036A1 (en)	1990-12-03
NO902449L (no)	1990-12-04
ES2067717T3 (es)	1995-04-01
HU207335B (en)	1993-03-29
EP0402312A3 (de)	1991-04-03
DD294945A5 (de)	1991-10-17
GB8912814D0 (en)	1989-07-19
FI902749A0 (fi)	1990-06-01
KR910000766A (ko)	1991-01-30
IL94537A0 (en)	1991-03-10
YU106890A (sh)	1992-07-20
NO902449D0 (no)	1990-06-01
EP0402312B1 (de)	1995-01-25
HUT54169A (en)	1991-01-28
ATE117693T1 (de)	1995-02-15

Publication	Publication Date	Title
NO177674C (no)	1995-11-01	Analogifremgangsmåte for fremstilling av terapeutisk aktive substituerte propan-fosfinsyre-forbindelser
HUT35629A (en)	1985-07-29	Preparations of plant growth controlling effect and containing 1-methyl-amino-cylopropane-1-carboxylic acid-derivatives as agent and process for the production of the agents
TW368501B (en)	1999-09-01	7-(2-aminoethyl)-benzothiazolones
DE68922408D1 (de)	1995-06-01	Neue Triazolopyrimidin- und Pyrazolopyrimidinderivate zur Behandlung von Kachexie.
AU1395283A (en)	1983-11-03	1-carboxyalkanoylindoline-2-carboxylic acid esters
LTIP704A (en)	1995-01-31	Process for the preparation of hexahydroazepines derivatives
FI902749A0 (fi)	1990-06-01	Menetelmä P-substituoitujen propaani-fosfiinihappoyhdisteiden valmistamiseksi
CS387391A3 (en)	1992-07-15	Phenylalkylaminoalkyl compounds, process of their preparation andmedicaments comprising said compounds
FI925875A0 (fi)	1992-12-23	Foerfarande foer framstaellning av nya som inhibitorer av proteolytiska enzymer anvaendbara 2-sackarinylmetyl- och 4,5,6,7-tetrahydro-2-sackarinylmetylfosfater, -fosfonater och -fosfinater
GB8511891D0 (en)	1985-06-19	Alkenoic acids
MY101645A (en)	1991-12-31	Phosphoric esters and process for preparing the same.
GR3022546T3 (en)	1997-05-31	Inositol phosphate analogues as calcium-antagonistic substances
ATE110730T1 (de)	1994-09-15	Verfahren zur herstellung von cephalosporinen.
IL109227A0 (en)	1994-07-31	Leustroducsin h, pharmaceutical composition containing the same, and processes for the preparation thereof