NO178194C - Analogifremgangsmåte for fremstilling av terapeutisk aktive naftyridin-derivater - Google Patents

Analogifremgangsmåte for fremstilling av terapeutisk aktive naftyridin-derivater

Info

Publication number
NO178194C
NO178194C NO903286A NO903286A NO178194C NO 178194 C NO178194 C NO 178194C NO 903286 A NO903286 A NO 903286A NO 903286 A NO903286 A NO 903286A NO 178194 C NO178194 C NO 178194C
Authority
NO
Norway
Prior art keywords
therapeutically active
analogous process
naphthyridine derivatives
preparing therapeutically
preparing
Prior art date
Application number
NO903286A
Other languages
English (en)
Other versions
NO903286D0 (no
NO903286L (no
NO178194B (no
Inventor
John Michael Domagala
Susan Elizabeth Hagen
John Steven Kiely
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of NO903286D0 publication Critical patent/NO903286D0/no
Publication of NO903286L publication Critical patent/NO903286L/no
Publication of NO178194B publication Critical patent/NO178194B/no
Publication of NO178194C publication Critical patent/NO178194C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/10—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Quinoline Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO903286A 1988-01-25 1990-07-24 Analogifremgangsmåte for fremstilling av terapeutisk aktive naftyridin-derivater NO178194C (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14746288A 1988-01-25 1988-01-25
US07/280,924 US4920120A (en) 1988-01-25 1988-12-09 Antibacterial agents
PCT/US1989/000278 WO1989006649A2 (en) 1988-01-25 1989-01-23 Antibacterial agents

Publications (4)

Publication Number Publication Date
NO903286D0 NO903286D0 (no) 1990-07-24
NO903286L NO903286L (no) 1990-07-24
NO178194B NO178194B (no) 1995-10-30
NO178194C true NO178194C (no) 1996-02-07

Family

ID=26844956

Family Applications (2)

Application Number Title Priority Date Filing Date
NO903286A NO178194C (no) 1988-01-25 1990-07-24 Analogifremgangsmåte for fremstilling av terapeutisk aktive naftyridin-derivater
NO942468A NO300263B1 (no) 1988-01-25 1994-06-30 Fremgangsmåte for fremstilling av 2-alkyl-3,4,6-trifluorbenzoesyre

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO942468A NO300263B1 (no) 1988-01-25 1994-06-30 Fremgangsmåte for fremstilling av 2-alkyl-3,4,6-trifluorbenzoesyre

Country Status (16)

Country Link
US (1) US4920120A (no)
EP (2) EP0326891B1 (no)
JP (2) JP2815119B2 (no)
KR (3) KR0130931B1 (no)
AT (1) ATE109471T1 (no)
AU (4) AU624118B2 (no)
CA (1) CA1340492C (no)
DE (1) DE68917163T2 (no)
DK (2) DK173057B1 (no)
ES (1) ES2056963T3 (no)
FI (1) FI93360C (no)
IE (1) IE65350B1 (no)
NO (2) NO178194C (no)
NZ (1) NZ227680A (no)
PT (1) PT89520B (no)
WO (1) WO1989006649A2 (no)

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EP0207420B1 (en) * 1985-06-26 1992-05-06 Daiichi Pharmaceutical Co., Ltd. Pyridonecarboxylic acid derivatives
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US5290934A (en) * 1987-04-16 1994-03-01 Otsuka Pharmaceutical Company, Limited Benzoheterocyclic compounds
US5563138A (en) * 1987-04-16 1996-10-08 Otsuka Pharmaceutical Company, Limited Benzoheterocyclic compounds
US5585491A (en) * 1988-01-25 1996-12-17 Otsuka Pharmaceutical Co., Ltd. Antibacterial agents
US5173484A (en) * 1988-02-05 1992-12-22 Bayer Aktiengesellschaft Quinolone- and naphthyridone carboxylic acid derivatives, process for their production, antibacterial compositions and feed additives containing them
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DE3910663A1 (de) * 1989-04-03 1990-10-04 Bayer Ag 5-alkylchinoloncarbonsaeuren
US5140033A (en) * 1989-04-03 1992-08-18 Bayer Aktiengesellschaft Antibacterial 5-alkylquinolonecarboxylic acids
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CA2030217A1 (en) * 1989-11-21 1991-05-22 Jun Imose Pyridone-carboxylic acid derivatives useful as veterinary medicines
DE4019023A1 (de) * 1990-06-14 1991-12-19 Bayer Ag Verfahren zur herstellung von chinolincarbonsaeuren
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SG144936A1 (en) 2003-09-10 2008-08-28 Kyorin Seiyaku Kk 7-(4-substituted-3-cyclopropylaminomethyl-1- pyrrolidinyl)quinolonecarboxylic acid derivative
KR100981351B1 (ko) 2003-10-29 2010-09-10 주식회사 엘지생명과학 7-클로로-1-사이클로프로필-6-플루오로-4-옥소-1,4-디하이드로-1,8-나프티리딘-3-카복실산의 제조방법
IN2014CN00532A (no) 2006-03-06 2015-04-03 Japan Tobacco Inc
KR101023635B1 (ko) 2006-03-06 2011-03-22 니뽄 다바코 산교 가부시키가이샤 4-옥소퀴놀린 화합물 제조 방법
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CN111620806B (zh) * 2020-06-12 2021-05-11 常州瑞明药业有限公司 一种氨氯地平中间体的制备方法

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AU5123690A (en) * 1989-03-13 1990-09-13 Bristol-Myers Squibb Company 5-substituted-1,4-dihydro-4-oxo-nephthyridine-3-carboxylate antibacterial agents
DE3910663A1 (de) * 1989-04-03 1990-10-04 Bayer Ag 5-alkylchinoloncarbonsaeuren

Also Published As

Publication number Publication date
AU3048389A (en) 1989-08-11
EP0326891A2 (en) 1989-08-09
AU2722495A (en) 1995-10-05
AU659444B2 (en) 1995-05-18
WO1989006649A2 (en) 1989-07-27
FI903696A0 (fi) 1990-07-23
IE65350B1 (en) 1995-10-18
DE68917163T2 (de) 1994-12-01
PT89520B (pt) 1994-02-28
NO942468D0 (no) 1994-06-30
KR0145958B1 (en) 1998-08-17
NO903286D0 (no) 1990-07-24
PT89520A (pt) 1989-10-04
AU2722395A (en) 1995-10-19
AU1388892A (en) 1992-07-09
KR0182275B1 (ko) 1999-05-01
NO300263B1 (no) 1997-05-05
FI93360C (fi) 1995-03-27
AU671575B2 (en) 1996-08-29
JPH10291959A (ja) 1998-11-04
NO903286L (no) 1990-07-24
KR19980703084A (ko) 1998-09-05
NO942468L (no) 1990-07-24
NO178194B (no) 1995-10-30
FI93360B (fi) 1994-12-15
ATE109471T1 (de) 1994-08-15
IE883900L (en) 1989-07-25
JP2815119B2 (ja) 1998-10-27
AU624118B2 (en) 1992-06-04
DK173057B1 (da) 1999-12-13
DK140996A (da) 1996-12-09
KR0130931B1 (ko) 1998-04-16
NZ227680A (en) 1991-11-26
JP2986154B2 (ja) 1999-12-06
WO1989006649A3 (en) 1989-12-28
EP0326891A3 (en) 1990-04-25
ES2056963T3 (es) 1994-10-16
DE68917163D1 (de) 1994-09-08
US4920120A (en) 1990-04-24
CA1340492C (en) 1999-04-13
EP0326891B1 (en) 1994-08-03
EP0398967A1 (en) 1990-11-28
JPH03502452A (ja) 1991-06-06
DK174690D0 (da) 1990-07-20
DK174690A (da) 1990-07-20
AU674272B2 (en) 1996-12-12
KR900700475A (ko) 1990-08-13

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