NO178697C - Analogifremgangsmåte for fremstilling av terapeutisk aktive pyrazolopyridin-forbindelser - Google Patents

Analogifremgangsmåte for fremstilling av terapeutisk aktive pyrazolopyridin-forbindelser

Info

Publication number: NO178697C
Authority: NO; Norway
Prior art keywords: alkyl; heterocyclic group; alkylamino; therapeutically active; analogous process
Prior art date: 1990-07-18

Application number

NO912805A

Other languages

English (en)

Norwegian (no)

Other versions

NO178697B (no

NO912805D0 (no

NO912805L (no

Inventor

Youichi Shiokawa

Atsushi Akahane

Hirohito Katayama

Takafumi Mitsunaga

Original Assignee

Fujisawa Pharmaceutical Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-07-18

Filing date

1991-07-17

Publication date

1996-05-15

1991-07-17 Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co

1991-07-17 Publication of NO912805D0 publication Critical patent/NO912805D0/no

1992-01-20 Publication of NO912805L publication Critical patent/NO912805L/no

1996-02-05 Publication of NO178697B publication Critical patent/NO178697B/no

1996-05-15 Publication of NO178697C publication Critical patent/NO178697C/no

Links

238000004519 manufacturing process Methods 0.000 title 1
150000005229 pyrazolopyridines Chemical class 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 11
125000000623 heterocyclic group Chemical group 0.000 abstract 5
125000003282 alkyl amino group Chemical group 0.000 abstract 4
125000001424 substituent group Chemical group 0.000 abstract 3
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
125000004093 cyano group Chemical group *C#N 0.000 abstract 2
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
239000004480 active ingredient Substances 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
125000004104 aryloxy group Chemical group 0.000 abstract 1
239000003937 drug carrier Substances 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
239000000546 pharmaceutical excipient Substances 0.000 abstract 1
-1 pyrazolopyridine compound Chemical class 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Hematology (AREA)
Biomedical Technology (AREA)
Obesity (AREA)
Neurosurgery (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Neurology (AREA)
Pain & Pain Management (AREA)
Endocrinology (AREA)
Immunology (AREA)
Rheumatology (AREA)
Urology & Nephrology (AREA)
Emergency Medicine (AREA)
Psychiatry (AREA)
Pulmonology (AREA)
Vascular Medicine (AREA)
Child & Adolescent Psychology (AREA)
Physical Education & Sports Medicine (AREA)
Reproductive Health (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)

NO912805A 1990-07-18 1991-07-17 Analogifremgangsmåte for fremstilling av terapeutisk aktive pyrazolopyridin-forbindelser NO178697C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB909015764A GB9015764D0 (en)	1990-07-18	1990-07-18	Pyrazolopyridine compound and processes for preparation thereof

Publications (4)

Publication Number	Publication Date
NO912805D0 NO912805D0 (no)	1991-07-17
NO912805L NO912805L (no)	1992-01-20
NO178697B NO178697B (no)	1996-02-05
NO178697C true NO178697C (no)	1996-05-15

Family

ID=10679258

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO912805A NO178697C (no)	1990-07-18	1991-07-17	Analogifremgangsmåte for fremstilling av terapeutisk aktive pyrazolopyridin-forbindelser

Country Status (20)

Country	Link
US (1)	US5204346A (de)
EP (1)	EP0467248B1 (de)
JP (1)	JP3123562B2 (de)
KR (1)	KR100219957B1 (de)
CN (1)	CN1042730C (de)
AT (1)	ATE172731T1 (de)
AU (1)	AU651353B2 (de)
CA (1)	CA2047283C (de)
DE (1)	DE69130412T2 (de)
DK (1)	DK0467248T3 (de)
ES (1)	ES2121760T3 (de)
FI (1)	FI96688C (de)
GB (1)	GB9015764D0 (de)
HU (1)	HU218666B (de)
IE (1)	IE912427A1 (de)
IL (1)	IL98872A (de)
NO (1)	NO178697C (de)
PH (1)	PH30486A (de)
PT (1)	PT98358B (de)
ZA (1)	ZA915376B (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5338743A (en) *	1988-06-06	1994-08-16	Fujisawa Pharmaceutical Co., Ltd.	New use of the adenosine antagonist
ATE211384T1 (de) *	1991-01-29	2002-01-15	Fujisawa Pharmaceutical Co	Verwendung von adenosinantagonisten zur vorbeugung und behandlung von pankreatitis und ulcera
DE4237656A1 (de) *	1992-06-13	1993-12-16	Merck Patent Gmbh	Benzimidazolderivate
CN1046724C (zh) *	1993-12-29	1999-11-24	藤泽药品工业株式会社	吡唑并吡啶化合物、含有它们的药物组合物、及其制法与用途
DE69731948D1 (de) *	1996-04-25	2005-01-20	Fujisawa Pharmaceutical Co	Mittel zur vorbeugung und heilung ischämischer darmlesion und ileus
AUPO111096A0 (en) *	1996-07-18	1996-08-08	Fujisawa Pharmaceutical Co., Ltd.	New compound
AU733034B2 (en) *	1996-07-18	2001-05-03	Fujisawa Pharmaceutical Co., Ltd.	Pyrazolopyridine compound and pharmaceutical use thereof
AU733316B2 (en) *	1996-10-04	2001-05-10	Kyorin Pharmaceutical Co. Ltd.	Pyrazolopyridylpyridazinone derivatives and process for preparing the same
EP0972525A4 (de) *	1997-03-18	2000-11-29	Fujisawa Pharmaceutical Co	Vorbeugende und heilende mittel gegen hyperphosphatämie
ATE281458T1 (de)	1997-09-05	2004-11-15	Glaxo Group Ltd	Pharmazeutische zusammensetzung, enthaltend 2,3- diaryl-pyrazolo(1,5-b)pyridazin derivate
US6060481A (en) *	1998-05-28	2000-05-09	The Penn State Research Foundation	Method for improving insulin sensitivity using an adenosine receptor antagonist
AU754094B2 (en) *	1998-06-01	2002-11-07	Astellas Pharma Inc.	Remedies for male sterility
WO1999067239A1 (en) *	1998-06-22	1999-12-29	Fujisawa Pharmaceutical Co., Ltd.	Pyrazolopyridine compounds and medicinal uses thereof
ATE275148T1 (de)	1998-11-03	2004-09-15	Glaxo Group Ltd	Pyrazolopyridin derivative als selektive cox-2 inhibitoren
WO2000052008A1 (en)	1999-02-27	2000-09-08	Glaxo Group Limited	Pyrazolopyridines
US20040152659A1 (en) *	1999-05-12	2004-08-05	Fujisawa Pharmaceutical Co. Ltd.	Method for the treatment of parkinson's disease comprising administering an A1A2a receptor dual antagonist
AUPQ441499A0 (en) *	1999-12-02	2000-01-06	Fujisawa Pharmaceutical Co., Ltd.	Novel compound
GB9930358D0 (en)	1999-12-22	2000-02-09	Glaxo Group Ltd	Process for the preparation of chemical compounds
PE20020506A1 (es)	2000-08-22	2002-07-09	Glaxo Group Ltd	Derivados de pirazol fusionados como inhibidores de la proteina cinasa
AUPQ969800A0 (en) *	2000-08-28	2000-09-21	Fujisawa Pharmaceutical Co., Ltd.	Pyrazolopyridine compound and pharmaceutical use thereof
ES2245380T3 (es)	2000-12-15	2006-01-01	Glaxo Group Limited	Pirazolopiridinas.
EP1377573B1 (de)	2000-12-15	2005-07-27	Glaxo Group Limited	Pyrazolopyridinderivate
US7153855B2 (en)	2001-03-08	2006-12-26	Smithkline Beecham Corporation	Pyrazolopyridinyl pyrimidine therapeutic compounds
EP1372643A1 (de)	2001-03-30	2004-01-02	Smithkline Beecham Corporation	Pyrazolopyridine, verfahren zu ihrer herstellung und verwendung als therapeutika
WO2002078701A1 (en) *	2001-03-30	2002-10-10	Smithkline Beecham Corporation	Use of pyrazolopyridines as therapeutic compounds
JP4219171B2 (ja)	2001-04-10	2009-02-04	スミスクラインビーチャムコーポレーション	抗ウイルス性ピラゾロピリジン化合物
US6756498B2 (en)	2001-04-27	2004-06-29	Smithkline Beecham Corporation	Process for the preparation of chemical compounds
AU2002305143A1 (en)	2001-04-27	2002-11-11	Smithkline Beecham Corporation	Pyrazolo'1,5-a!pyridine derivatives
AUPR548601A0 (en) *	2001-06-06	2001-06-28	Fujisawa Pharmaceutical Co., Ltd.	Pyrazolopyrazinecompound and pharmaceutical use thereof
KR20040018281A (ko)	2001-06-21	2004-03-02	스미스클라인 비참 코포레이션	포진 바이러스 감염의 예방 및 치료를 위한 이미다조[1，２－α]피리딘 유도체
ES2286272T3 (es) *	2001-09-07	2007-12-01	Smithkline Beecham Corporation	Pirizolo-piridinas para el tratamiento de infecciones por herpes.
US7244740B2 (en)	2001-10-05	2007-07-17	Smithkline Beecham Corporation	Imidazo-pyridine derivatives for use in the treatment of herpes viral infection
WO2003050120A1 (en) *	2001-12-11	2003-06-19	Smithkline Beecham Corporation	Pyrazolo-pyridine derivatives as antiherpes agents
WO2004033454A1 (en) *	2002-10-03	2004-04-22	Smithkline Beecham Corporation	Therapeutic compounds based on pyrazolopyridine derivatives
UA103319C2 (en)	2008-05-06	2013-10-10	Глаксосмитклайн Ллк	Thiazole- and oxazole-benzene sulfonamide compounds
MX2011001333A (es) *	2008-08-04	2011-03-15	Astrazeneca Ab	Derivados de pirazolo [3, 4] pirimidin-4-ilo y sus usos para tratar la diabetes y obesidad.
MX2021011316A (es) *	2019-03-20	2021-10-13	Goldfinch Bio Inc	Piridazinonas y metodos de uso de estas.

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4024255A (en) *	1973-04-05	1977-05-17	Allen & Hanburys Limited	Tetrazole containing naphthyridine-3-carboxamides
US4304777A (en) *	1979-08-30	1981-12-08	Sterling Drug Inc.	6-(Pyridinyl)-3(2H)-pyridazinones and their use as cardiotonics
JPS5826802A (ja) *	1981-08-10	1983-02-17	Sankyo Co Ltd	農園芸用殺菌剤
US4666902A (en) *	1983-06-20	1987-05-19	Cassella Aktiengesellschaft	Tetrahydropyridazinone derivatives, processes for their preparation and their use
HU195645B (en) *	1985-10-30	1988-06-28	Gyogyszerkutato Intezet	Process for preparing novel 3(2h)-pyridazinone derivatives and pharmaceutical compositions comprising the same
US4925849A (en) *	1987-06-15	1990-05-15	Fujisawa Pharmaceutical Company, Ltd.	Pharmaceutically useful pyrazolopyridines
JPH0710865B2 (ja) *	1987-06-26	1995-02-08	日本バイエルアグロケム株式会社	ニトロ置換ヘテロ環式化合物及び殺虫剤
GB8901423D0 (en) *	1989-01-23	1989-03-15	Fujisawa Pharmaceutical Co	Pyrazolopyridine compound and processes for preparation thereof

1990
- 1990-07-18 GB GB909015764A patent/GB9015764D0/en active Pending
1991
- 1991-07-09 PH PH42760A patent/PH30486A/en unknown
- 1991-07-10 ZA ZA915376A patent/ZA915376B/xx unknown
- 1991-07-11 IE IE242791A patent/IE912427A1/en not_active Application Discontinuation
- 1991-07-13 DE DE69130412T patent/DE69130412T2/de not_active Expired - Fee Related
- 1991-07-13 DK DK91111715T patent/DK0467248T3/da active
- 1991-07-13 EP EP91111715A patent/EP0467248B1/de not_active Expired - Lifetime
- 1991-07-13 AT AT91111715T patent/ATE172731T1/de not_active IP Right Cessation
- 1991-07-13 ES ES91111715T patent/ES2121760T3/es not_active Expired - Lifetime
- 1991-07-15 US US07/729,688 patent/US5204346A/en not_active Expired - Fee Related
- 1991-07-16 JP JP03268125A patent/JP3123562B2/ja not_active Expired - Fee Related
- 1991-07-16 AU AU80468/91A patent/AU651353B2/en not_active Ceased
- 1991-07-17 CA CA002047283A patent/CA2047283C/en not_active Expired - Fee Related
- 1991-07-17 IL IL9887291A patent/IL98872A/en not_active IP Right Cessation
- 1991-07-17 HU HU397/91A patent/HU218666B/hu not_active IP Right Cessation
- 1991-07-17 FI FI913446A patent/FI96688C/fi active
- 1991-07-17 NO NO912805A patent/NO178697C/no unknown
- 1991-07-17 PT PT98358A patent/PT98358B/pt not_active IP Right Cessation
- 1991-07-17 CN CN91105592A patent/CN1042730C/zh not_active Expired - Fee Related
- 1991-07-18 KR KR1019910012195A patent/KR100219957B1/ko not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CA2047283C (en)	2002-07-02
NO178697B (no)	1996-02-05
NO912805D0 (no)	1991-07-17
GB9015764D0 (en)	1990-09-05
ZA915376B (en)	1992-04-29
ES2121760T3 (es)	1998-12-16
PT98358B (pt)	1999-01-29
IL98872A0 (en)	1992-07-15
CN1059143A (zh)	1992-03-04
FI913446A0 (fi)	1991-07-17
DE69130412T2 (de)	1999-04-22
JP3123562B2 (ja)	2001-01-15
DE69130412D1 (de)	1998-12-03
ATE172731T1 (de)	1998-11-15
EP0467248A3 (en)	1992-03-11
FI96688B (fi)	1996-04-30
AU8046891A (en)	1992-01-23
US5204346A (en)	1993-04-20
FI913446L (fi)	1992-01-19
EP0467248B1 (de)	1998-10-28
FI96688C (fi)	1996-08-12
CA2047283A1 (en)	1992-01-19
KR100219957B1 (ko)	1999-09-01
NO912805L (no)	1992-01-20
HU912397D0 (en)	1991-12-30
HU218666B (hu)	2000-10-28
PH30486A (en)	1997-05-28
IE912427A1 (en)	1992-01-29
HUT58735A (en)	1992-03-30
IL98872A (en)	1996-12-05
KR920002603A (ko)	1992-02-28
DK0467248T3 (da)	1999-07-05
CN1042730C (zh)	1999-03-31
EP0467248A2 (de)	1992-01-22
AU651353B2 (en)	1994-07-21
JPH04253978A (ja)	1992-09-09
PT98358A (pt)	1992-05-29

Publication	Publication Date	Title
NO912805L (no)	1992-01-20	Fremgangsmaate for fremstilling av pyrazolopyridin-forbindelser.
NO890723D0 (no)	1989-02-21	Fremgangsmaate for fremstilling av terapeutisk aktive 3-alkenyl-1-azabicyklo(3.2.0)hept2-en-2-karboksylsyrederivater.
NO176356C (no)	1995-03-22	Analogifremgangsmåte for fremstilling av nye terapeutisk aktive pyrazolopyridinforbindelser
IL107426A0 (en)	1994-01-25	Heterocyclic compounds, processes for the preparation thereof, and pharmaceutical compositions containing the same
DE68916071D1 (de)	1994-07-21	3-Pyrrolidinylthio-1-azabicyclo (3.2.0)hept-2-en-2-carbonsäure-Verbindungen.
GR3017850T3 (en)	1996-01-31	Pyrazolopyridine compound and processes for preparation thereof.
DK96786A (da)	1986-09-05	Aminosyrederivater
HUT56089A (en)	1991-07-29	Process for producing quinazoline derivatives and pharmaceutical compositions containing them
NO174886C (no)	1994-07-27	Analogifremgangsmåte for fremstilling av terapeutisk aktive pyrrolidin-derivater
GB8721016D0 (en)	1987-10-14	Cephem compounds