NO178965C - Taxan-derivater, fremstilling derav, samt deres anvendelse som krefthindrende middel - Google Patents

Taxan-derivater, fremstilling derav, samt deres anvendelse som krefthindrende middel

Info

Publication number: NO178965C
Authority: NO; Norway
Prior art keywords: preparation; anticancer agents; taxane derivatives; cyclotaxanes; new
Prior art date: 1992-03-06

Application number

NO930773A

Other languages

English (en)

Norwegian (no)

Other versions

NO178965B (no

NO930773D0 (no

NO930773L (no

Inventor

Ezio Bombardelli

Bruno Gabetta

Original Assignee

Indena Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-03-06

Filing date

1993-03-03

Publication date

1996-07-10

1993-03-03 Application filed by Indena Spa filed Critical Indena Spa

1993-03-03 Publication of NO930773D0 publication Critical patent/NO930773D0/no

1993-09-07 Publication of NO930773L publication Critical patent/NO930773L/no

1996-04-01 Publication of NO178965B publication Critical patent/NO178965B/no

1996-07-10 Publication of NO178965C publication Critical patent/NO178965C/no

Links

239000002246 antineoplastic agent Substances 0.000 title 1
DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 title 1
241000196324 Embryophyta Species 0.000 abstract 1
241001116500 Taxus Species 0.000 abstract 1
230000002634 anti-blastic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/612—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
- C07C69/618—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety having unsaturation outside the six-membered aromatic ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/56—Ring systems containing bridged rings
- C07C2603/58—Ring systems containing bridged rings containing three rings
- C07C2603/76—Ring systems containing bridged rings containing three rings containing at least one ring with more than six ring members
- C07C2603/80—Ring systems containing bridged rings containing three rings containing at least one ring with more than six ring members containing eight-membered rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/56—Ring systems containing bridged rings
- C07C2603/86—Ring systems containing bridged rings containing four rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Epoxy Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Steroid Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

NO930773A 1992-03-06 1993-03-03 Taxan-derivater, fremstilling derav, samt deres anvendelse som krefthindrende middel NO178965C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
ITMI920526A IT1254515B (it)	1992-03-06	1992-03-06	Tassani di interesse oncologico, loro metodo di preparazione ed uso

Publications (4)

Publication Number	Publication Date
NO930773D0 NO930773D0 (no)	1993-03-03
NO930773L NO930773L (no)	1993-09-07
NO178965B NO178965B (no)	1996-04-01
NO178965C true NO178965C (no)	1996-07-10

Family

ID=11362316

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO930773A NO178965C (no)	1992-03-06	1993-03-03	Taxan-derivater, fremstilling derav, samt deres anvendelse som krefthindrende middel

Country Status (15)

Country	Link
US (1)	US5250722A (fr)
EP (1)	EP0559018B1 (fr)
JP (1)	JPH0641010A (fr)
KR (1)	KR100255524B1 (fr)
AT (1)	ATE137734T1 (fr)
CA (1)	CA2091002C (fr)
DE (2)	DE69302508T2 (fr)
DK (1)	DK0559018T3 (fr)
ES (1)	ES2049690T3 (fr)
FI (1)	FI112208B (fr)
GR (2)	GR930300141T1 (fr)
HK (1)	HK1007556A1 (fr)
IT (1)	IT1254515B (fr)
NO (1)	NO178965C (fr)
RU (2)	RU2112770C1 (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5475120A (en) *	1990-11-02	1995-12-12	University Of Florida	Method for the isolation and purification of taxol and its natural analogues
JP2646942B2 (ja) *	1991-08-12	1997-08-27	松下電器産業株式会社	ガード体付電子部品の打抜装置および打抜方法
IT1261667B (it) *	1993-05-20	1996-05-29		Tassano ad attivita' antitumorale.
US5628978A (en) *	1994-12-23	1997-05-13	Intevep, S.A.	MTW zeolite for cracking feedstock into olefins and isoparaffins
US6177456B1 (en)	1995-10-02	2001-01-23	Xechem International, Inc.	Monohalocephalomannines having anticancer and antileukemic activity and method of preparation therefor
US5840748A (en) *	1995-10-02	1998-11-24	Xechem International, Inc.	Dihalocephalomannine and methods of use therefor
US5807888A (en) *	1995-12-13	1998-09-15	Xechem International, Inc.	Preparation of brominated paclitaxel analogues and their use as effective antitumor agents
US5854278A (en) *	1995-12-13	1998-12-29	Xechem International, Inc.	Preparation of chlorinated paclitaxel analogues and use thereof as antitumor agents
US5654448A (en) *	1995-10-02	1997-08-05	Xechem International, Inc.	Isolation and purification of paclitaxel from organic matter containing paclitaxel, cephalomannine and other related taxanes
US5795909A (en) *	1996-05-22	1998-08-18	Neuromedica, Inc.	DHA-pharmaceutical agent conjugates of taxanes
US5919815A (en) *	1996-05-22	1999-07-06	Neuromedica, Inc.	Taxane compounds and compositions
US6576636B2 (en)	1996-05-22	2003-06-10	Protarga, Inc.	Method of treating a liver disorder with fatty acid-antiviral agent conjugates
DK0914116T3 (da) *	1996-05-22	2000-11-20	Protarga Inc	Kompositstoffer omfattende konjugater af cis-docosahexaensyre og Taxotere
US7235583B1 (en) *	1999-03-09	2007-06-26	Luitpold Pharmaceuticals, Inc.,	Fatty acid-anticancer conjugates and uses thereof
EP2266607A3 (fr)	1999-10-01	2011-04-20	Immunogen, Inc.	Des immunoconjugués pour le traitement des cancers.
EP1423107B1 (fr) *	2001-03-23	2012-05-09	Luitpold Pharmaceuticals, Inc.	Conjugues d'agents pharmaceutiques et d'alcools gras
JP2005500988A (ja)	2001-03-23	2005-01-13	ルイトポルド・ファーマシューティカルズ・インコーポレーテッド	脂肪族アミン薬物複合体
CA2468953C (fr) *	2001-11-29	2010-05-11	Daiichi Pharmaceutical Co., Ltd.	Cristaux de derive de taxane et procede de production associe
US7201507B2 (en)	2003-12-25	2007-04-10	Ichikoh Industries, Ltd.	Projector type vehicle light
JP4405279B2 (ja)	2004-02-17	2010-01-27	市光工業株式会社	プロジェクタ型車両用灯具
US7772177B2 (en)	2005-05-18	2010-08-10	Aegera Therapeutics, Inc.	BIR domain binding compounds
SG171682A1 (en)	2006-05-16	2011-06-29	Aegera Therapeutics Inc	Iap bir domain binding compounds
EP3263583A1 (fr)	2010-02-12	2018-01-03	Pharmascience Inc.	Composés de liaison du domaine iap bir
CN105541631B (zh) *	2015-10-26	2017-09-05	云南西力生物技术股份有限公司	绣线菊阿替生素A(spiratisanin A)及其制备方法和在药物上的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2601675B1 (fr) *	1986-07-17	1988-09-23	Rhone Poulenc Sante	Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
US5059699A (en) *	1990-08-28	1991-10-22	Virginia Tech Intellectual Properties, Inc.	Water soluble derivatives of taxol
US5380916A (en) *	1990-11-02	1995-01-10	University Of Florida	Method for the isolation and purification of taxane derivatives

1992
- 1992-03-06 IT ITMI920526A patent/IT1254515B/it active
- 1992-05-11 US US07/881,047 patent/US5250722A/en not_active Expired - Lifetime
1993
- 1993-02-19 DK DK93102632.2T patent/DK0559018T3/da active
- 1993-02-19 EP EP93102632A patent/EP0559018B1/fr not_active Expired - Lifetime
- 1993-02-19 DE DE69302508T patent/DE69302508T2/de not_active Expired - Fee Related
- 1993-02-19 DE DE93102632T patent/DE559018T1/de active Pending
- 1993-02-19 AT AT93102632T patent/ATE137734T1/de not_active IP Right Cessation
- 1993-02-19 ES ES93102632T patent/ES2049690T3/es not_active Expired - Lifetime
- 1993-03-03 NO NO930773A patent/NO178965C/no unknown
- 1993-03-04 KR KR1019930003212A patent/KR100255524B1/ko not_active Expired - Fee Related
- 1993-03-04 RU RU93004649A patent/RU2112770C1/ru not_active IP Right Cessation
- 1993-03-04 FI FI930977A patent/FI112208B/fi active
- 1993-03-04 RU RU93004623A patent/RU2119485C1/ru not_active IP Right Cessation
- 1993-03-04 JP JP5067348A patent/JPH0641010A/ja active Pending
- 1993-03-04 CA CA002091002A patent/CA2091002C/fr not_active Expired - Fee Related
1994
- 1994-02-28 GR GR930300141T patent/GR930300141T1/el unknown
1996
- 1996-05-09 GR GR960401123T patent/GR3019871T3/el unknown
1998
- 1998-06-25 HK HK98106815A patent/HK1007556A1/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
DK0559018T3 (da)	1996-08-19
ES2049690T1 (es)	1994-05-01
KR930019597A (ko)	1993-10-18
GR930300141T1 (en)	1994-02-28
RU2119485C1 (ru)	1998-09-27
ITMI920526A0 (it)	1992-03-06
IT1254515B (it)	1995-09-25
FI930977A0 (fi)	1993-03-04
DE69302508D1 (de)	1996-06-13
DE69302508T2 (de)	1996-09-12
US5250722A (en)	1993-10-05
DE559018T1 (de)	1994-03-17
ATE137734T1 (de)	1996-05-15
CA2091002C (fr)	2004-06-08
JPH0641010A (ja)	1994-02-15
GR3019871T3 (en)	1996-08-31
FI112208B (fi)	2003-11-14
KR100255524B1 (ko)	2000-05-01
CA2091002A1 (fr)	1993-09-07
HK1007556A1 (en)	1999-04-16
ES2049690T3 (es)	1996-07-16
ITMI920526A1 (it)	1993-09-06
NO178965B (no)	1996-04-01
NO930773D0 (no)	1993-03-03
EP0559018B1 (fr)	1996-05-08
FI930977L (fi)	1993-09-07
RU2112770C1 (ru)	1998-06-10
NO930773L (no)	1993-09-07
EP0559018A1 (fr)	1993-09-08

Publication	Publication Date	Title
NO178965C (no)	1996-07-10	Taxan-derivater, fremstilling derav, samt deres anvendelse som krefthindrende middel
NO943002D0 (no)	1994-08-15	Fosfono-oksymetyletere av taxanderivater
DK0559019T3 (da)	2000-03-27	14-beta-hydroxy-10-deacetyl-baccatin III og derivater deraf som antitumormidler
DE3776063D1 (en)	1992-02-27	Bryostatine.
IL89921A0 (en)	1989-12-15	1,3-dioxolane derivatives and pharmaceutical compositions containing the same
NO307336B1 (no)	2000-03-20	2-[(Dihydro)pyrazolyl-3'-oksylmetylen]anilider, anvendelse derav, samt middel inneholdende forbindelsen og mellomprodukter for fremstilling av forbindelsen
AU674378B2 (en)	1996-12-19	Use of 2-amino-6-A-propylamino-4,5,6, 7-tetrahydrobenzothiazole (pramipexol) as an anti-depressantdrug
ATE184009T1 (de)	1999-09-15	Halichondrine: zytotoxische polyäther-makrolide
RU93004649A (ru)	1996-06-20	Производные таксана, способ их получения и использование в онкологии,фармкомпозиция
NO951283D0 (no)	1995-04-03	Nye taxanderivater, deres fremstilling samt farmasöytiske preparater inneholdende derivatene
IT1254990B (it)	1995-10-11	Glutatione come agente chemioprotettivo
DE69131163D1 (de)	1999-05-27	Asthma heilmittel
FI981359A0 (fi)	1993-09-17	Uudet tiomarinolin johdannaiset ja menetelmät niiden valmistamiseksi
DE69024060D1 (de)	1996-01-18	Osteogenesis-stimulierende mittel.
ATE90685T1 (de)	1993-07-15	Disaccharidderivate.
FI903779A0 (fi)	1990-07-27	S-substituerade betatioacrylamider och deras anvaendning som mikrobicider.
FI950101A0 (fi)	1995-01-09	4-oksa-1-atsabisyklo 3,2,0 -7heptanoni-johdannaiset kasvainten vastaisina aineina
DK0610076T3 (da)	1999-01-25	Cytotoksiske forbindelser