DK0559018T3 - Taxanderivater, deres fremstilling og anvendelse indenfor onkologi - Google Patents

Taxanderivater, deres fremstilling og anvendelse indenfor onkologi

Info

Publication number: DK0559018T3
Authority: DK; Denmark
Prior art keywords: preparation; oncology; application; taxane derivatives; cyclotaxanes
Prior art date: 1992-03-06

Application number

DK93102632.2T

Other languages

Danish (da)

English (en)

Inventor

Ezio Bombardelli

Bruno Gabetta

Original Assignee

Indena Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-03-06

Filing date

1993-02-19

Publication date

1996-08-19

1993-02-19 Application filed by Indena Spa filed Critical Indena Spa

1996-08-19 Application granted granted Critical

1996-08-19 Publication of DK0559018T3 publication Critical patent/DK0559018T3/da

Links

DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 title 1
241000196324 Embryophyta Species 0.000 abstract 1
241001116500 Taxus Species 0.000 abstract 1
230000002634 anti-blastic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/612—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety
- C07C69/618—Esters of carboxylic acids having a carboxyl group bound to an acyclic carbon atom and having a six-membered aromatic ring in the acid moiety having unsaturation outside the six-membered aromatic ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/56—Ring systems containing bridged rings
- C07C2603/58—Ring systems containing bridged rings containing three rings
- C07C2603/76—Ring systems containing bridged rings containing three rings containing at least one ring with more than six ring members
- C07C2603/80—Ring systems containing bridged rings containing three rings containing at least one ring with more than six ring members containing eight-membered rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/56—Ring systems containing bridged rings
- C07C2603/86—Ring systems containing bridged rings containing four rings

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Epoxy Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Steroid Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK93102632.2T 1992-03-06 1993-02-19 Taxanderivater, deres fremstilling og anvendelse indenfor onkologi DK0559018T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
ITMI920526A IT1254515B (it)	1992-03-06	1992-03-06	Tassani di interesse oncologico, loro metodo di preparazione ed uso

Publications (1)

Publication Number	Publication Date
DK0559018T3 true DK0559018T3 (da)	1996-08-19

Family

ID=11362316

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK93102632.2T DK0559018T3 (da)	1992-03-06	1993-02-19	Taxanderivater, deres fremstilling og anvendelse indenfor onkologi

Country Status (15)

Country	Link
US (1)	US5250722A (fr)
EP (1)	EP0559018B1 (fr)
JP (1)	JPH0641010A (fr)
KR (1)	KR100255524B1 (fr)
AT (1)	ATE137734T1 (fr)
CA (1)	CA2091002C (fr)
DE (2)	DE69302508T2 (fr)
DK (1)	DK0559018T3 (fr)
ES (1)	ES2049690T3 (fr)
FI (1)	FI112208B (fr)
GR (2)	GR930300141T1 (fr)
HK (1)	HK1007556A1 (fr)
IT (1)	IT1254515B (fr)
NO (1)	NO178965C (fr)
RU (2)	RU2119485C1 (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5475120A (en) *	1990-11-02	1995-12-12	University Of Florida	Method for the isolation and purification of taxol and its natural analogues
JP2646942B2 (ja) *	1991-08-12	1997-08-27	松下電器産業株式会社	ガード体付電子部品の打抜装置および打抜方法
IT1261667B (it) *	1993-05-20	1996-05-29		Tassano ad attivita' antitumorale.
US5628978A (en) *	1994-12-23	1997-05-13	Intevep, S.A.	MTW zeolite for cracking feedstock into olefins and isoparaffins
US5854278A (en) *	1995-12-13	1998-12-29	Xechem International, Inc.	Preparation of chlorinated paclitaxel analogues and use thereof as antitumor agents
US5654448A (en) *	1995-10-02	1997-08-05	Xechem International, Inc.	Isolation and purification of paclitaxel from organic matter containing paclitaxel, cephalomannine and other related taxanes
US5840748A (en) *	1995-10-02	1998-11-24	Xechem International, Inc.	Dihalocephalomannine and methods of use therefor
US6177456B1 (en)	1995-10-02	2001-01-23	Xechem International, Inc.	Monohalocephalomannines having anticancer and antileukemic activity and method of preparation therefor
US5807888A (en) *	1995-12-13	1998-09-15	Xechem International, Inc.	Preparation of brominated paclitaxel analogues and their use as effective antitumor agents
WO1997044026A1 (fr) *	1996-05-22	1997-11-27	Neuromedica, Inc.	Compositions contenant des conjugues d'acide cis-docosahexanoique et de taxotere
US5919815A (en) *	1996-05-22	1999-07-06	Neuromedica, Inc.	Taxane compounds and compositions
US6576636B2 (en)	1996-05-22	2003-06-10	Protarga, Inc.	Method of treating a liver disorder with fatty acid-antiviral agent conjugates
US5795909A (en)	1996-05-22	1998-08-18	Neuromedica, Inc.	DHA-pharmaceutical agent conjugates of taxanes
US7235583B1 (en)	1999-03-09	2007-06-26	Luitpold Pharmaceuticals, Inc.,	Fatty acid-anticancer conjugates and uses thereof
AU775373B2 (en)	1999-10-01	2004-07-29	Immunogen, Inc.	Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
AU2002303164A1 (en)	2001-03-23	2002-10-08	Protarga, Inc.	Fatty amine drug conjugates
ATE556706T1 (de) *	2001-03-23	2012-05-15	Luitpold Pharm Inc	Fettalkohol-arzneimittel-konjugate
DE60224440T2 (de) *	2001-11-29	2009-01-02	Daiichi Sankyo Co., Ltd.	Kristalle von taxanderivaten und verfahren zu deren herstellung
US7201507B2 (en)	2003-12-25	2007-04-10	Ichikoh Industries, Ltd.	Projector type vehicle light
JP4405279B2 (ja)	2004-02-17	2010-01-27	市光工業株式会社	プロジェクタ型車両用灯具
US7772177B2 (en)	2005-05-18	2010-08-10	Aegera Therapeutics, Inc.	BIR domain binding compounds
AU2007250443B2 (en)	2006-05-16	2013-06-13	Pharmascience Inc.	IAP BIR domain binding compounds
WO2011098904A1 (fr)	2010-02-12	2011-08-18	Aegera Therapeutics, Inc.	Composés de liaison au domaine iap bir
CN105541631B (zh) *	2015-10-26	2017-09-05	云南西力生物技术股份有限公司	绣线菊阿替生素A(spiratisanin A)及其制备方法和在药物上的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2601675B1 (fr) *	1986-07-17	1988-09-23	Rhone Poulenc Sante	Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
US5059699A (en) *	1990-08-28	1991-10-22	Virginia Tech Intellectual Properties, Inc.	Water soluble derivatives of taxol
US5380916A (en) *	1990-11-02	1995-01-10	University Of Florida	Method for the isolation and purification of taxane derivatives

1992
- 1992-03-06 IT ITMI920526A patent/IT1254515B/it active
- 1992-05-11 US US07/881,047 patent/US5250722A/en not_active Expired - Lifetime
1993
- 1993-02-19 EP EP93102632A patent/EP0559018B1/fr not_active Expired - Lifetime
- 1993-02-19 DK DK93102632.2T patent/DK0559018T3/da active
- 1993-02-19 ES ES93102632T patent/ES2049690T3/es not_active Expired - Lifetime
- 1993-02-19 DE DE69302508T patent/DE69302508T2/de not_active Expired - Fee Related
- 1993-02-19 DE DE93102632T patent/DE559018T1/de active Pending
- 1993-02-19 AT AT93102632T patent/ATE137734T1/de not_active IP Right Cessation
- 1993-03-03 NO NO930773A patent/NO178965C/no unknown
- 1993-03-04 JP JP5067348A patent/JPH0641010A/ja active Pending
- 1993-03-04 KR KR1019930003212A patent/KR100255524B1/ko not_active Expired - Fee Related
- 1993-03-04 RU RU93004623A patent/RU2119485C1/ru not_active IP Right Cessation
- 1993-03-04 CA CA002091002A patent/CA2091002C/fr not_active Expired - Fee Related
- 1993-03-04 RU RU93004649A patent/RU2112770C1/ru not_active IP Right Cessation
- 1993-03-04 FI FI930977A patent/FI112208B/fi active
1994
- 1994-02-28 GR GR930300141T patent/GR930300141T1/el unknown
1996
- 1996-05-09 GR GR960401123T patent/GR3019871T3/el unknown
1998
- 1998-06-25 HK HK98106815A patent/HK1007556A1/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
NO930773D0 (no)	1993-03-03
FI112208B (fi)	2003-11-14
DE69302508T2 (de)	1996-09-12
DE559018T1 (de)	1994-03-17
KR930019597A (ko)	1993-10-18
FI930977L (fi)	1993-09-07
RU2119485C1 (ru)	1998-09-27
DE69302508D1 (de)	1996-06-13
EP0559018A1 (fr)	1993-09-08
JPH0641010A (ja)	1994-02-15
KR100255524B1 (ko)	2000-05-01
GR3019871T3 (en)	1996-08-31
CA2091002C (fr)	2004-06-08
GR930300141T1 (en)	1994-02-28
NO930773L (no)	1993-09-07
HK1007556A1 (en)	1999-04-16
ATE137734T1 (de)	1996-05-15
CA2091002A1 (fr)	1993-09-07
NO178965C (no)	1996-07-10
FI930977A0 (fi)	1993-03-04
ITMI920526A0 (it)	1992-03-06
US5250722A (en)	1993-10-05
ES2049690T3 (es)	1996-07-16
RU2112770C1 (ru)	1998-06-10
EP0559018B1 (fr)	1996-05-08
IT1254515B (it)	1995-09-25
ES2049690T1 (es)	1994-05-01
NO178965B (no)	1996-04-01
ITMI920526A1 (it)	1993-09-06

Publication	Publication Date	Title
DK0559018T3 (da)	1996-08-19	Taxanderivater, deres fremstilling og anvendelse indenfor onkologi
IL113462A0 (en)	1995-07-31	Substituted pyridylpyrazoles, their preparation and pesticidal compositions containing them
NO943002L (no)	1995-02-20	Fosfono-oksymetyletere av taxanderivater
PT960881E (pt)	2003-09-30	Sintese do taxol e dos seus derivados
NO891415L (no)	1989-10-09	Fremstilling av substituerte flavonoidforbindelser og salter og farmasoeytiske preparater derav.
RU93004649A (ru)	1996-06-20	Производные таксана, способ их получения и использование в онкологии,фармкомпозиция
NO944406D0 (no)	1994-11-17	Nye 7 se inhibitorer
ATE184009T1 (de)	1999-09-15	Halichondrine: zytotoxische polyäther-makrolide
ES2127181T3 (es)	1999-04-16	11-beta-aril-gona-4,9-dien-3-onas.
DE58902899D1 (de)	1993-01-14	2',3'-dideoxypurinnucleosid/purinnucleosid-phosphorylase-inhibitor kombinationstherapie und zusammensetzungen dafuer.
DE69002520D1 (de)	1993-09-09	Azeotropaehnliche zusammensetzungen von 1,1-dichlor-2,2,2-trifluoraethan und 1,1-dochlor-1-fluoraethan.
NO933328L (no)	1994-03-21	Nye thiomarinolderivater og fremgangsmåte for deres fremstilling
NO903281D0 (no)	1990-07-24	S-substituerte beta-tioakrylamider og anvendelse derav som mikrobiocider.
DE59203799D1 (de)	1995-11-02	Acylierte Aminophenol-Derivate.
ATE222255T1 (de)	2002-08-15	14-substituierte marcfortine und derivate als antiparasitäre mittel
FR2580636B1 (fr)	1987-05-15	Nouveaux derives acryliques de l'uree
DE68928885D1 (de)	1999-02-04	1-Dimethylcarbamoyl-1H-1,2,4-triazole-substituiert in Stellungen 3 und 5
ATE88893T1 (de)	1993-05-15	Antimalariazusammenstellungen, gebrauchmachend von quinidin, artemisinin und ihren derivaten.
ATE82855T1 (de)	1992-12-15	2',3'-dideoxypurinnucleosid/purinnucleosidphosphorylase-inhibitor kombinationstherapie und zusammensetzungen dafuer.
ES1025077Y (es)	1994-07-01	Nueva variedad de portainjerto de cerezo "brokgrove".