NO179519C - Analogifremgangsmåte for fremstilling av 3-(1,2-benzisoksazol-3-yl)-4-pyridinaminer og derivater derav - Google Patents

Analogifremgangsmåte for fremstilling av 3-(1,2-benzisoksazol-3-yl)-4-pyridinaminer og derivater derav

Info

Publication number: NO179519C
Authority: NO; Norway
Prior art keywords: pyridinamines; benzisoxazol; hydrogen; derivatives; loweralkyl
Prior art date: 1990-08-13

Application number

NO913142A

Other languages

English (en)

Norwegian (no)

Other versions

NO913142D0 (no

NO913142L (no

NO179519B (no

Inventor

Joseph Thomas Klein

Richard Charles Effland

Original Assignee

Hoechst Marion Roussel Inc

Hoechst Roussel Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-08-13

Filing date

1991-08-12

Publication date

1996-10-23

1991-08-12 Application filed by Hoechst Marion Roussel Inc, Hoechst Roussel Pharma filed Critical Hoechst Marion Roussel Inc

1991-08-12 Publication of NO913142D0 publication Critical patent/NO913142D0/no

1992-02-14 Publication of NO913142L publication Critical patent/NO913142L/no

1996-07-15 Publication of NO179519B publication Critical patent/NO179519B/no

1996-10-23 Publication of NO179519C publication Critical patent/NO179519C/no

Links

XFGBLXXLIPBUAV-UHFFFAOYSA-N 3-(1,2-benzoxazol-3-yl)pyridin-4-amine Chemical class NC1=CC=NC=C1C1=NOC2=CC=CC=C12 XFGBLXXLIPBUAV-UHFFFAOYSA-N 0.000 title abstract 3
150000002431 hydrogen Chemical group 0.000 abstract 3
229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
208000024827 Alzheimer disease Diseases 0.000 abstract 2
125000003710 aryl alkyl group Chemical group 0.000 abstract 2
206010039966 Senile dementia Diseases 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
229940035676 analgesics Drugs 0.000 abstract 1
239000000730 antalgic agent Substances 0.000 abstract 1
239000002260 anti-inflammatory agent Substances 0.000 abstract 1
230000006949 cholinergic function Effects 0.000 abstract 1
230000019771 cognition Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000003247 decreasing effect Effects 0.000 abstract 1
239000003623 enhancer Substances 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical group 0.000 abstract 1
-1 loweralkyl Chemical group 0.000 abstract 1
230000007074 memory dysfunction Effects 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
230000003287 optical effect Effects 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
208000017520 skin disease Diseases 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

NO913142A 1990-08-13 1991-08-12 Analogifremgangsmåte for fremstilling av 3-(1,2-benzisoksazol-3-yl)-4-pyridinaminer og derivater derav NO179519C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/566,932 US5055476A (en)	1990-08-13	1990-08-13	3-(1,2-benzisoxazol-3-yl)-4-pyridinamines and derivatives

Publications (4)

Publication Number	Publication Date
NO913142D0 NO913142D0 (no)	1991-08-12
NO913142L NO913142L (no)	1992-02-14
NO179519B NO179519B (no)	1996-07-15
NO179519C true NO179519C (no)	1996-10-23

Family

ID=24265033

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO913142A NO179519C (no)	1990-08-13	1991-08-12	Analogifremgangsmåte for fremstilling av 3-(1,2-benzisoksazol-3-yl)-4-pyridinaminer og derivater derav

Country Status (24)

Country	Link
US (1)	US5055476A (cs)
EP (1)	EP0471297B1 (cs)
JP (1)	JP3057829B2 (cs)
KR (1)	KR100191386B1 (cs)
AT (1)	ATE130004T1 (cs)
AU (1)	AU633791B2 (cs)
CA (1)	CA2048959C (cs)
CZ (1)	CZ280568B6 (cs)
DE (1)	DE69114405T2 (cs)
DK (1)	DK0471297T3 (cs)
ES (1)	ES2079531T3 (cs)
FI (1)	FI103970B1 (cs)
GR (1)	GR3018184T3 (cs)
HU (1)	HU213201B (cs)
IE (1)	IE70597B1 (cs)
IL (1)	IL99166A (cs)
MX (1)	MX9100639A (cs)
NO (1)	NO179519C (cs)
NZ (1)	NZ239326A (cs)
PT (1)	PT98645B (cs)
RU (1)	RU2012561C1 (cs)
TW (1)	TW202446B (cs)
YU (1)	YU140991A (cs)
ZA (1)	ZA916342B (cs)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5308826A (en) *	1993-04-22	1994-05-03	Zeneca Limited	Herbicidal 4-substituted pyridyl-3-carbinols
EP0758323A1 (en) *	1994-05-02	1997-02-19	Zeneca Limited	Herbicidal hydroxybenzyl-substituted heteroaryl compounds and derivatives thereof
US5595958A (en) *	1994-05-02	1997-01-21	Zeneca Limited	3-substituted pyridine compounds and derivatives thereof
JP4263240B2 (ja) *	1995-11-09	2009-05-13	サノフィ−アベンティス	５−フェニル−３−（ピペリジン−４−イル）−１，３，４−オキサジアゾール−２（３ｈ）−オン誘導体、及びその５−ｈｔ４又はｈ３レセプターリガンドとしての用途
FR2762316B1 (fr) *	1997-04-18	1999-12-17	Sanofi Synthelabo	Derives de 5-aryl-3-(8-azabicyclo[3.2.1] octan-3-yl)-1,3,4- oxadiazol-2(3h)-one, leur preparation et leur application en therapeutique
US9073947B2 (en)	2011-06-10	2015-07-07	Merck Patent Gmbh	Compositions and methods for the production of pyrimidine and pyridine compounds with BTK inhibitory activity
RU2626650C2 (ru) *	2015-08-31	2017-07-31	Федеральное государственное бюджетное образовательное учреждение высшего образования "Пермский государственный национальный исследовательский университет"	2-Арил-2,4-дигидрокси-2,5-дигидро-3-гетерил-5-оксо-1Н-пиррол-1-ил-4-метилбелзолсульфаниламиды, обладающие анальгетической активностью
EP4429465A1 (en)	2021-11-10	2024-09-18	Symrise AG	Compositions comprising trpm8 agonistic cooling agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4355037A (en) *	1981-11-12	1982-10-19	Hoechst-Roussel Pharmaceuticals	3-(4-Piperidyl)-1,2-benzisoxales
IL66866A (en) *	1982-04-09	1987-08-31	Hoechst Roussel Pharma	1-(3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl)-4-(substituted)-piperazines and-piperidines,a process for the preparation thereof,and pharmaceutical compositions containing them
CA1335289C (en) *	1987-10-26	1995-04-18	Fujio Antoku	Piperidinyl benzisoxazole derivatives, their production and pharmaceutical use
MY107955A (en) *	1990-07-27	1996-07-15	Ici Plc	Fungicides.

1990
- 1990-08-13 US US07/566,932 patent/US5055476A/en not_active Expired - Fee Related
1991
- 1991-08-03 TW TW080106082A patent/TW202446B/zh active
- 1991-08-08 ES ES91113335T patent/ES2079531T3/es not_active Expired - Lifetime
- 1991-08-08 DK DK91113335.3T patent/DK0471297T3/da active
- 1991-08-08 DE DE69114405T patent/DE69114405T2/de not_active Expired - Fee Related
- 1991-08-08 EP EP91113335A patent/EP0471297B1/en not_active Expired - Lifetime
- 1991-08-08 AT AT91113335T patent/ATE130004T1/de not_active IP Right Cessation
- 1991-08-09 NZ NZ239326A patent/NZ239326A/en unknown
- 1991-08-09 FI FI913800A patent/FI103970B1/fi active
- 1991-08-12 AU AU81765/91A patent/AU633791B2/en not_active Ceased
- 1991-08-12 NO NO913142A patent/NO179519C/no unknown
- 1991-08-12 MX MX9100639A patent/MX9100639A/es not_active IP Right Cessation
- 1991-08-12 CZ CS912489A patent/CZ280568B6/cs not_active IP Right Cessation
- 1991-08-12 IE IE285191A patent/IE70597B1/en not_active IP Right Cessation
- 1991-08-12 ZA ZA916342A patent/ZA916342B/xx unknown
- 1991-08-12 RU SU915001260A patent/RU2012561C1/ru active
- 1991-08-12 PT PT98645A patent/PT98645B/pt not_active IP Right Cessation
- 1991-08-12 CA CA002048959A patent/CA2048959C/en not_active Expired - Fee Related
- 1991-08-12 IL IL9916691A patent/IL99166A/en not_active IP Right Cessation
- 1991-08-12 JP JP3201713A patent/JP3057829B2/ja not_active Expired - Fee Related
- 1991-08-12 HU HU912673A patent/HU213201B/hu not_active IP Right Cessation
- 1991-08-13 KR KR1019910013939A patent/KR100191386B1/ko not_active Expired - Fee Related
- 1991-08-14 YU YU140991A patent/YU140991A/sh unknown
1995
- 1995-11-22 GR GR950403309T patent/GR3018184T3/el unknown

Also Published As

Publication number	Publication date
ZA916342B (en)	1992-04-29
CA2048959C (en)	2003-07-29
US5055476A (en)	1991-10-08
FI103970B (fi)	1999-10-29
NZ239326A (en)	1994-04-27
FI913800A0 (fi)	1991-08-09
KR920004383A (ko)	1992-03-27
HUT61755A (en)	1993-03-01
ATE130004T1 (de)	1995-11-15
DE69114405D1 (de)	1995-12-14
TW202446B (cs)	1993-03-21
ES2079531T3 (es)	1996-01-16
EP0471297B1 (en)	1995-11-08
PT98645B (pt)	1999-01-29
NO913142D0 (no)	1991-08-12
IL99166A (en)	1995-12-08
AU8176591A (en)	1992-02-20
KR100191386B1 (ko)	1999-06-15
HU912673D0 (en)	1992-01-28
RU2012561C1 (ru)	1994-05-15
CA2048959A1 (en)	1992-02-14
IE70597B1 (en)	1996-12-11
FI913800L (fi)	1992-02-14
NO913142L (no)	1992-02-14
NO179519B (no)	1996-07-15
GR3018184T3 (en)	1996-02-29
CS248991A3 (en)	1992-03-18
JP3057829B2 (ja)	2000-07-04
FI103970B1 (fi)	1999-10-29
HU213201B (en)	1997-03-28
EP0471297A1 (en)	1992-02-19
YU140991A (sh)	1995-01-31
PT98645A (pt)	1992-06-30
DK0471297T3 (da)	1996-03-04
AU633791B2 (en)	1993-02-04
DE69114405T2 (de)	1996-05-02
IE912851A1 (en)	1992-02-26
MX9100639A (es)	1992-04-01
CZ280568B6 (cs)	1996-02-14
JPH05112562A (ja)	1993-05-07
IL99166A0 (en)	1992-07-15

Publication	Publication Date	Title
FI102069B1 (fi)	1998-10-15	Menetelmä terapeuttisesti käyttökelpoisten indolijohdannaisten valmistamiseksi
GR3030798T3 (en)	1999-11-30	2-(Piperidin-4-yl, pyridin-4-yl and tetrahydropyridin-4-yl)benzofuran-7-ol and carbamate derivatives, their preparation and their use as acetylcholinesterase inhibitors.
AU633791B2 (en)	1993-02-04	3-(1,2-benzisoxazol-3-yl)-4-pyridinamines and derivatives
AU640590B2 (en)	1993-08-26	3-(1h-indazol-3-yl)-4-pyridinamines
PT92234A (pt)	1990-05-31	Processo para a preparacao de 1,2,3,4-tetraidro-1,9-acridinodiaminas
FI96308C (fi)	1996-06-10	Menetelmä terapeuttisesti käyttökelpoisten 9-aminotetrahydroakridiinien ja niiden johdannaisten valmistamiseksi
HU912674D0 (en)	1992-01-28	Derivatives of 1-(pyridyl-alkyl)-1h-indole or -indole and process for producing said compounds
HU912675D0 (en)	1992-01-28	Process for producing derivatives of carbamoil-1-(pyridinyl-alkyl)-1h-indole and -indole