NO180194C - 6-£X-(2-hydroksyetyl)aminoalkyl|-5,11-diokso-5,6-dihydro-11-H-indeno£1,2-c|isokinoliner og anvendelse derav til fremstilling av medikamenter, samt medikament inneholdende slike kinoliner - Google Patents

6-£X-(2-hydroksyetyl)aminoalkyl|-5,11-diokso-5,6-dihydro-11-H-indeno£1,2-c|isokinoliner og anvendelse derav til fremstilling av medikamenter, samt medikament inneholdende slike kinoliner

Info

Publication number
NO180194C
NO180194C NO940542A NO940542A NO180194C NO 180194 C NO180194 C NO 180194C NO 940542 A NO940542 A NO 940542A NO 940542 A NO940542 A NO 940542A NO 180194 C NO180194 C NO 180194C
Authority
NO
Norway
Prior art keywords
indeno
derivatives
dioxo
dihydro
hydroxyethyl
Prior art date
Application number
NO940542A
Other languages
English (en)
Norwegian (no)
Other versions
NO940542D0 (no
NO940542L (no
NO180194B (no
Inventor
Jiri Michalsky
Jiri Hrbata
Jiri Krepelka
Milan Melka
Milan Miko
Milan Hruby
Milan Ferenc
Eva Skacelova
Irena Kejhova
Ruzena Reichlova
Anna Kargerova
Jitka Sediva
Alois Kolonicny
Josef Urbanec
Original Assignee
Vyzk Ustav Farm Biochem Sp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vyzk Ustav Farm Biochem Sp filed Critical Vyzk Ustav Farm Biochem Sp
Publication of NO940542D0 publication Critical patent/NO940542D0/no
Publication of NO940542L publication Critical patent/NO940542L/no
Publication of NO180194B publication Critical patent/NO180194B/no
Publication of NO180194C publication Critical patent/NO180194C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/18—Ring systems of four or more rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
NO940542A 1991-08-29 1994-02-17 6-£X-(2-hydroksyetyl)aminoalkyl|-5,11-diokso-5,6-dihydro-11-H-indeno£1,2-c|isokinoliner og anvendelse derav til fremstilling av medikamenter, samt medikament inneholdende slike kinoliner NO180194C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CS912669A CZ281473B6 (cs) 1991-08-29 1991-08-29 Deriváty 6-/X-(2-hydroxyethyl)aminoalkyl/-5,11 -dioxo-5,6-dihydro-11H-indeno/1,2-c/-isochinolinu a způsob jejich výroby
PCT/CS1992/000026 WO1993005023A1 (en) 1991-08-29 1992-08-27 6((2-hydroxyethyl)amino alkyl)-5,11-dioxo-5,6-dihydro-11-h-indeno(1,2-c)isoquinoline and their use as antineoplastic agents

Publications (4)

Publication Number Publication Date
NO940542D0 NO940542D0 (no) 1994-02-17
NO940542L NO940542L (no) 1994-02-17
NO180194B NO180194B (no) 1996-11-25
NO180194C true NO180194C (no) 1997-03-05

Family

ID=5364459

Family Applications (1)

Application Number Title Priority Date Filing Date
NO940542A NO180194C (no) 1991-08-29 1994-02-17 6-£X-(2-hydroksyetyl)aminoalkyl|-5,11-diokso-5,6-dihydro-11-H-indeno£1,2-c|isokinoliner og anvendelse derav til fremstilling av medikamenter, samt medikament inneholdende slike kinoliner

Country Status (15)

Country Link
EP (1) EP0643699B1 (pl)
JP (1) JPH07500581A (pl)
AT (1) ATE144499T1 (pl)
AU (1) AU663729B2 (pl)
CA (1) CA2116680A1 (pl)
CZ (1) CZ281473B6 (pl)
DE (1) DE69214842T2 (pl)
DK (1) DK0643699T3 (pl)
FI (1) FI107256B (pl)
HU (1) HU217551B (pl)
NO (1) NO180194C (pl)
PL (1) PL169572B1 (pl)
RU (1) RU2120939C1 (pl)
SK (1) SK266991A3 (pl)
WO (1) WO1993005023A1 (pl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3141148B2 (ja) * 1995-08-08 2001-03-05 大鵬薬品工業株式会社 縮合インダン誘導体及びその塩
AU765135B2 (en) * 1998-10-14 2003-09-11 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Novel indenoisoquinolines as antineoplastic agents
US20030096833A1 (en) 2001-08-31 2003-05-22 Jagtap Prakash G. Substituted ideno[1,2-c]isoquinoline derivatives and methods of use thereof
US6956035B2 (en) 2001-08-31 2005-10-18 Inotek Pharmaceuticals Corporation Isoquinoline derivatives and methods of use thereof
EP1603567A4 (en) * 2003-02-28 2006-10-18 Inotek Pharmaceuticals Corp TETRACYCLIC BENZAMIDE DERIVATIVES AND METHOD OF USE THEREOF
US20050228007A1 (en) 2004-02-26 2005-10-13 Prakash Jagtap Isoquinoline derivatives and methods of use thereof
JP2008531562A (ja) 2005-02-25 2008-08-14 イノテック ファーマシューティカルズ コーポレイション 四環アミノ化合物および四環カルボキサミド化合物およびこれらの使用法
CN101316592A (zh) 2005-08-24 2008-12-03 伊诺泰克制药公司 茚并异喹啉酮类似物及其用法
KR20090115879A (ko) 2007-02-28 2009-11-09 이노텍 파마슈티컬스 코포레이션 인데노이소퀴놀리논 유사체와 이의 이용 방법
CN102250000A (zh) * 2010-05-17 2011-11-23 中国人民解放军第二军医大学 茚并喹啉酮类化合物及其制备方法和用途
TWI642658B (zh) * 2017-11-01 2018-12-01 國立臺灣師範大學 茚並異喹啉衍生物的製備方法

Also Published As

Publication number Publication date
FI107256B (fi) 2001-06-29
EP0643699B1 (en) 1996-10-23
AU2583592A (en) 1993-04-05
PL169572B1 (pl) 1996-08-30
DE69214842T2 (de) 1997-02-27
CA2116680A1 (en) 1993-03-18
WO1993005023A1 (en) 1993-03-18
NO940542D0 (no) 1994-02-17
HU217551B (hu) 2000-02-28
FI940895A0 (fi) 1994-02-25
RU2120939C1 (ru) 1998-10-27
DE69214842D1 (de) 1996-11-28
SK278794B6 (sk) 1998-03-04
AU663729B2 (en) 1995-10-19
ATE144499T1 (de) 1996-11-15
CZ266991A3 (en) 1993-03-17
JPH07500581A (ja) 1995-01-19
DK0643699T3 (da) 1997-04-28
NO940542L (no) 1994-02-17
NO180194B (no) 1996-11-25
EP0643699A1 (en) 1995-03-22
HUT70396A (en) 1995-10-30
HU9400563D0 (en) 1994-05-30
SK266991A3 (en) 1998-03-04
FI940895A7 (fi) 1994-02-25
CZ281473B6 (cs) 1996-10-16

Similar Documents

Publication Publication Date Title
DE59005587D1 (de) Salicylaldehyd- und Salicylsäurederivate sowie deren Schwefelanaloge, Verfahren zu ihrer Herstellung und ihre Verwendung als Herbizide und Bioregulatoren.
WO1991013055A3 (en) New aryl- and heteroarylethenylene derivatives and process for their preparation
NO180194C (no) 6-£X-(2-hydroksyetyl)aminoalkyl|-5,11-diokso-5,6-dihydro-11-H-indeno£1,2-c|isokinoliner og anvendelse derav til fremstilling av medikamenter, samt medikament inneholdende slike kinoliner
PT99134A (pt) Processo para a preparacao de derivados da piperazina
FI940414A0 (fi) Kinoliini- tai kinatsoliinijohdannaiset, niiden valmistus ja käyttö
Badawey et al. Benzimidazole condensed ring systems. XI. Synthesis of some substituted cycloalkyl pyrido [1, 2-a] benzimidazoles with anticipated antineoplastic activity
HU913062D0 (en) Method for producing benzol, pyridyl and pyridine derivatives and pharmaceutical preparatives containing such compounds
NO172577C (no) Fremgangsmaate og mellomprodukter ved fremstilling av substituerte indolinonderivater
US5972955A (en) Water soluble C-ring analogues of 20(S)-camptothecin
Loza-Mejía et al. Synthesis, cytotoxic evaluation, and DNA binding of novel thiazolo [5, 4-b] quinoline derivatives
RU94043792A (ru) 6-(х-(2-гидроксиэтил)аминоалкил)-5,11-диоксо-5,6-дигидро-11-н-индено (1,2-с) изохинолины и их применение в качестве противоопухолевых средств
ATE90348T1 (de) Pyrido(2,3-d>pyrimidin-derivate.
ES8307818A1 (es) Procedimiento para preparar derivados de cefalosporina.
Sami et al. 6-and 7-Substituted 2-[2 ‘-(Dimethylamino) ethyl]-1, 2-dihydro-3 H-dibenz [de, h] isoquinoline-1, 3-diones: Synthesis, Nucleophilic Displacements, Antitumor Activity, and Quantitative Structure− Activity Relationships
Attaby REACTIONS WITH PYRIDINETHIONE DERIVATIVES: SYNTHESIS AND CHARACTERIZATION OF THIENYL [2, 3-b] PYRIDINE, PYRIDO [2′, 3′: 4, 5] THIENO [2, 3-b] PYRIDAZINE, PYRIDO [2′, 3′: 4, 5] THIENO [2, 3-b]-PYRIMIDINONE, PYRAZOLINO [3′, 4′: 4, 5] THIENO [2, 3-b] PYRIDINE AND AMINOPYRAZOLO [3, 4-b] PYRIDINE DERIVATIVES
Santilli et al. Synthesis and antibacterial evaluation of 1, 2, 3, 4-tetrahydro-4-oxo-1, 8-naphthyridine-3-carboxylic acid esters, carbonitriles, and carboxamides
FR2597103B1 (fr) Procede de preparation de derives d'oxazinobenzothiazine 6,6-dioxyde
US4587052A (en) 1H-pyrrolo-[2,1-C][1,4]benzodiazepine-2-acrylamide compounds having antitumor activity
PT99250A (pt) Processo para a preparacao de derivados de piperazina
Lee et al. Spectroscopic Studies of Conjugated Uracil $ Derivatives^+ $
Vomero et al. Synthesis of 1, 2, 4‐triazolo [4′, 3′: 1, 6] pyridazino [4, 5‐b] quinoline derivatives
KURASAWA et al. Synthesis of 4-Substituted 1, 2-Dihydropyridazino [3, 4-b] quinoxalines from 3-(N, N-Dimethylaminocarbonyl) furo [2, 3-b] quinoxaline
FI860364A0 (fi) Nya 6-aminometyl-furo-(3,4-c) -pyridinderivat, deras framstaellning och dessa innehaollande terapeutiska blandningar.
Yutilov et al. Synthesis of Ticlopidine Analogs Based on Spinaceamine and 2-Azaspinaceamine.

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees

Free format text: LAPSED IN FEBRUARY 2003