NO180634C - Analogifremgangsmåte for fremstilling av terapeutisk aktive imidazoquinoksalinforbindelser - Google Patents

Analogifremgangsmåte for fremstilling av terapeutisk aktive imidazoquinoksalinforbindelser

Info

Publication number: NO180634C
Authority: NO; Norway
Prior art keywords: preparation; therapeutically active; branched; alkyl; hydrogen
Prior art date: 1989-11-22

Application number

NO921887A

Other languages

English (en)

Norwegian (no)

Other versions

NO921887L (no

NO180634B (no

NO921887D0 (no

Inventor

Frank Waetjen

Holger Claus Hansen

Original Assignee

Novo Nordisk As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-11-22

Filing date

1992-05-13

Publication date

1997-05-21

1992-05-13 Application filed by Novo Nordisk As filed Critical Novo Nordisk As

1992-05-13 Publication of NO921887L publication Critical patent/NO921887L/no

1992-05-13 Publication of NO921887D0 publication Critical patent/NO921887D0/no

1997-02-10 Publication of NO180634B publication Critical patent/NO180634B/no

1997-05-21 Publication of NO180634C publication Critical patent/NO180634C/no

Links

YELMWJNXDALKFE-UHFFFAOYSA-N 3h-imidazo[4,5-f]quinoxaline Chemical class N1=CC=NC2=C(NC=N3)C3=CC=C21 YELMWJNXDALKFE-UHFFFAOYSA-N 0.000 title abstract 2
238000002360 preparation method Methods 0.000 title abstract 2
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 3
150000002431 hydrogen Chemical class 0.000 abstract 3
229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical group 0.000 abstract 2
125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
125000006272 (C3-C7) cycloalkyl group Chemical group 0.000 abstract 1
125000000882 C2-C6 alkenyl group Chemical group 0.000 abstract 1
241000124008 Mammalia Species 0.000 abstract 1
229940125681 anticonvulsant agent Drugs 0.000 abstract 1
239000001961 anticonvulsive agent Substances 0.000 abstract 1
239000002249 anxiolytic agent Substances 0.000 abstract 1
230000000949 anxiolytic effect Effects 0.000 abstract 1
229940005530 anxiolytics Drugs 0.000 abstract 1
125000006196 aroyl alkyl group Chemical group 0.000 abstract 1
125000003710 aryl alkyl group Chemical group 0.000 abstract 1
210000004556 brain Anatomy 0.000 abstract 1
230000003920 cognitive function Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000003326 hypnotic agent Substances 0.000 abstract 1
230000000147 hypnotic effect Effects 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Neurosurgery (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

NO921887A 1989-11-22 1992-05-13 Analogifremgangsmåte for fremstilling av terapeutisk aktive imidazoquinoksalinforbindelser NO180634C (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DK588489A DK588489D0 (da)	1989-11-22	1989-11-22	Heterocykliske forbindelser, deres fremstilling og anvendelse
PCT/DK1990/000301 WO1991007407A1 (en)	1989-11-22	1990-11-22	Imidazoquinoxaline compounds, their preparation and use

Publications (4)

Publication Number	Publication Date
NO921887L NO921887L (no)	1992-05-13
NO921887D0 NO921887D0 (no)	1992-05-13
NO180634B NO180634B (no)	1997-02-10
NO180634C true NO180634C (no)	1997-05-21

Family

ID=8145919

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO921887A NO180634C (no)	1989-11-22	1992-05-13	Analogifremgangsmåte for fremstilling av terapeutisk aktive imidazoquinoksalinforbindelser

Country Status (20)

Country	Link
US (1)	US5116841A (de)
EP (1)	EP0502038B1 (de)
JP (1)	JPH05503082A (de)
KR (1)	KR920703594A (de)
AT (1)	ATE148703T1 (de)
AU (1)	AU645276B2 (de)
CA (1)	CA2073041A1 (de)
DE (1)	DE69029910T2 (de)
DK (2)	DK588489D0 (de)
ES (1)	ES2098276T3 (de)
FI (1)	FI97227C (de)
GR (1)	GR3023124T3 (de)
HU (1)	HUT63421A (de)
IE (1)	IE904156A1 (de)
IL (1)	IL96373A (de)
NO (1)	NO180634C (de)
NZ (1)	NZ236157A (de)
PT (1)	PT95973B (de)
WO (1)	WO1991007407A1 (de)
ZA (1)	ZA909303B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK151890D0 (da) *	1990-06-22	1990-06-22	Ferrosan As	Heterocykliske forbindelser deres fremstilling og brug
US5683998A (en) *	1991-04-23	1997-11-04	Toray Industries, Inc.	Tricyclic triazolo derivatives, processes for producing the same and the uses of the same
JPH07503970A (ja) *	1992-02-19	1995-04-27	ジ・アップジョン・カンパニー	ＣＮＳ活性を有する３−置換イミダゾ（１，５−ａ）−キノキサリン類およびキナゾリン類
US5792766A (en)	1996-03-13	1998-08-11	Neurogen Corporation	Imidazo 1,5-c! quinazolines; a new class of GABA brain receptor ligands
SE9902268D0 (sv) *	1999-06-16	1999-06-16	Astra Ab	Pharmaceutically active compounds
US20040180898A1 (en) *	2003-03-03	2004-09-16	Bang-Chi Chen	Processes for preparing imidazoquinoxalinones, heterocyclic-substituted imidazopyrazinones, imidazoquinoxalines and heterocyclic-substituted imidazopyrazines
CN114702495A (zh)	2015-11-20	2022-07-05	福马治疗有限公司	作为泛素-特异性蛋白酶1抑制剂的嘌呤酮

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK476885D0 (da) *	1985-10-17	1985-10-17	Ferrosan As	Heterocycliske forbindelser og fremgangsmaader til fremstilling heraf
DK155524C (da) *	1987-03-18	1989-09-11	Ferrosan As	Kondenserede imidazolderivater og farmaceutiske praeparater indeholdende disse
DK160876C (da) *	1987-12-08	1991-10-14	Novo Nordisk As	Imidazoquinoxalinforbindelser, fremgangsmaade til deres fremstilling, anvendelse af forbindelserne og farmaceutiske praeparater, hvori forbindelserne indgaar
DK626288D0 (da) *	1988-11-10	1988-11-10	Ferrosan As	Kemisk proces til fremstilling af imidazoquinoxaliner og mellemprodukter til brug i processen
DK588389D0 (da) *	1989-11-22	1989-11-22	Ferrosan As	Heterocykliske forbindelser, deres fremstilling og anvendelse
FR2659329B1 (fr) *	1990-03-09	1994-06-03	Adir	Nouveaux derives d'imidazo [1,2-c] quinazoline, leur procede de preparation et les compositions pharmaceutiques les renfermant.

1989
- 1989-11-22 DK DK588489A patent/DK588489D0/da not_active Application Discontinuation
1990
- 1990-11-16 IL IL9637390A patent/IL96373A/en not_active IP Right Cessation
- 1990-11-19 IE IE415690A patent/IE904156A1/en unknown
- 1990-11-20 NZ NZ236157A patent/NZ236157A/xx unknown
- 1990-11-20 ZA ZA909303A patent/ZA909303B/xx unknown
- 1990-11-20 US US07/615,707 patent/US5116841A/en not_active Expired - Fee Related
- 1990-11-22 ES ES90917268T patent/ES2098276T3/es not_active Expired - Lifetime
- 1990-11-22 DE DE69029910T patent/DE69029910T2/de not_active Expired - Fee Related
- 1990-11-22 HU HU9201710A patent/HUT63421A/hu unknown
- 1990-11-22 JP JP3500072A patent/JPH05503082A/ja active Pending
- 1990-11-22 CA CA002073041A patent/CA2073041A1/en not_active Abandoned
- 1990-11-22 EP EP90917268A patent/EP0502038B1/de not_active Expired - Lifetime
- 1990-11-22 DK DK90917268.6T patent/DK0502038T3/da active
- 1990-11-22 AU AU67535/90A patent/AU645276B2/en not_active Ceased
- 1990-11-22 PT PT95973A patent/PT95973B/pt not_active IP Right Cessation
- 1990-11-22 KR KR1019920701200A patent/KR920703594A/ko not_active Ceased
- 1990-11-22 WO PCT/DK1990/000301 patent/WO1991007407A1/en not_active Ceased
- 1990-11-22 AT AT90917268T patent/ATE148703T1/de not_active IP Right Cessation
1992
- 1992-05-13 NO NO921887A patent/NO180634C/no unknown
- 1992-05-19 FI FI922267A patent/FI97227C/fi not_active IP Right Cessation
1997
- 1997-04-14 GR GR970400785T patent/GR3023124T3/el unknown

Also Published As

Publication number	Publication date
HUT63421A (en)	1993-08-30
US5116841A (en)	1992-05-26
EP0502038B1 (de)	1997-02-05
ES2098276T3 (es)	1997-05-01
NO921887L (no)	1992-05-13
DK588489D0 (da)	1989-11-22
IL96373A0 (en)	1991-08-16
KR920703594A (ko)	1992-12-18
DE69029910D1 (de)	1997-03-20
FI922267L (fi)	1992-05-19
AU645276B2 (en)	1994-01-13
FI97227C (fi)	1996-11-11
DE69029910T2 (de)	1997-07-10
AU6753590A (en)	1991-06-13
DK0502038T3 (da)	1997-08-11
CA2073041A1 (en)	1991-05-23
HU9201710D0 (en)	1992-09-28
PT95973B (pt)	1998-01-30
ATE148703T1 (de)	1997-02-15
IE904156A1 (en)	1991-05-22
NZ236157A (en)	1992-08-26
FI922267A0 (fi)	1992-05-19
WO1991007407A1 (en)	1991-05-30
NO180634B (no)	1997-02-10
EP0502038A1 (de)	1992-09-09
GR3023124T3 (en)	1997-07-30
ZA909303B (en)	1991-09-25
PT95973A (pt)	1991-09-13
FI97227B (fi)	1996-07-31
NO921887D0 (no)	1992-05-13
IL96373A (en)	1994-10-21
JPH05503082A (ja)	1993-05-27

Publication	Publication Date	Title
DK322088D0 (da)	1988-06-14	Imidazoquicxalinforbindelser, deres fremstilling og anvendelse
PT83573B (pt)	1988-10-14	Processo de preparacao de compostos heterociclicos de quinazolina e de seus intermediarios e de composicoes farmaceuticas
FI922267A0 (fi)	1992-05-19	Menetelmä uusien terapeuttisesti käyttökelpoisten 3-isoksatsolyyli-4-okso-imidatso/1,5-a/kinoksaliinijohdannaisten valmistamiseksi
DE69009493D1 (de)	1994-07-07	Imidazoquinoxalinverbindungen, deren herstellung und verwendung.
DK0535104T3 (da)	1997-01-13	Heterocyliske forbindelser deres fremstilling og anvendelse
NO884431D0 (no)	1988-10-05	Fremgangsmaate for fremstilling av heterocykliske forbindelser.
DK555688A (da)	1989-04-07	Heterocykliske forbindelser, deres fremstilling og anvendelse
SE8304111D0 (sv)	1983-07-22	Amino derivatives of benzylidene-pyrrolo(2,1-b)-quinazolines and benzylidene-pyrido(2,1-b)quinazolines