NO20001402L - Substituerte kromanderivater - Google Patents

Substituerte kromanderivater

Info

Publication number: NO20001402L
Authority: NO; Norway
Prior art keywords: alkyl; enantiomers; cycloalkyl; aryl; substituted
Prior art date: 1997-09-18

Application number

NO20001402A

Other languages

English (en)

Norwegian (no)

Other versions

NO20001402D0 (no

Inventor

Stefan Berg

Martin Nyloef

Svante Ross

Seth-Olov Thorberg

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-09-18

Filing date

2000-03-17

Publication date

2000-05-09

2000-03-17 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2000-03-17 Publication of NO20001402D0 publication Critical patent/NO20001402D0/no

2000-05-09 Publication of NO20001402L publication Critical patent/NO20001402L/no

Links

VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical class [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 title 1
125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
125000000520 N-substituted aminocarbonyl group Chemical group [*]NC(=O)* 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
239000012458 free base Substances 0.000 abstract 1
125000001072 heteroaryl group Chemical group 0.000 abstract 1
125000005842 heteroatom Chemical group 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000004193 piperazinyl group Chemical group 0.000 abstract 1
125000005936 piperidyl group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000012453 solvate Substances 0.000 abstract 1
229910052717 sulfur Inorganic materials 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Psychiatry (AREA)
Addiction (AREA)
Reproductive Health (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Endocrinology (AREA)
Pain & Pain Management (AREA)
Obesity (AREA)
Nutrition Science (AREA)
Diabetes (AREA)
Hematology (AREA)
Psychology (AREA)
Hospice & Palliative Care (AREA)
Rheumatology (AREA)
Child & Adolescent Psychology (AREA)
Urology & Nephrology (AREA)
Gynecology & Obstetrics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyrane Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

NO20001402A 1997-09-18 2000-03-17 Substituerte kromanderivater NO20001402L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE9703377A SE9703377D0 (sv)	1997-09-18	1997-09-18	New compounds
PCT/SE1998/001603 WO1999014212A1 (en)	1997-09-18	1998-09-09	Substituted chroman derivatives

Publications (2)

Publication Number	Publication Date
NO20001402D0 NO20001402D0 (no)	2000-03-17
NO20001402L true NO20001402L (no)	2000-05-09

Family

ID=20408297

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20001402A NO20001402L (no)	1997-09-18	2000-03-17	Substituerte kromanderivater

Country Status (23)

Country	Link
US (4)	US6479497B1 (de)
EP (1)	EP1025095B1 (de)
JP (1)	JP4150161B2 (de)
KR (1)	KR20010024077A (de)
CN (1)	CN1278810A (de)
AR (1)	AR015449A1 (de)
AT (1)	ATE255098T1 (de)
AU (1)	AU734580B2 (de)
BR (1)	BR9812238A (de)
CA (1)	CA2304037A1 (de)
DE (1)	DE69820102T2 (de)
EE (1)	EE200000140A (de)
HR (1)	HRP20000132A2 (de)
HU (1)	HUP0100684A3 (de)
IL (1)	IL135073A0 (de)
IS (1)	IS5402A (de)
NO (1)	NO20001402L (de)
PL (1)	PL339664A1 (de)
SE (1)	SE9703377D0 (de)
SK (1)	SK2862000A3 (de)
TR (1)	TR200000736T2 (de)
WO (1)	WO1999014212A1 (de)
ZA (1)	ZA987813B (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE9703377D0 (sv) *	1997-09-18	1997-09-18	Astra Ab	New compounds
WO2002020500A2 (en) *	2000-09-01	2002-03-14	Icos Corporation	Materials and methods to potentiate cancer treatment
NZ535574A (en)	2001-01-16	2006-07-28	Astrazeneca Ab	Therapeutic heterocyclic compounds
MXPA03006268A (es)	2001-01-16	2003-09-22	Astrazeneca Ab	Compuestos terapeuticos de cromano.
US8404681B2 (en)	2003-03-24	2013-03-26	Luitpold Pharmaceuticals, Inc.	Xanthones, thioxanthones and acridinones as DNA-PK inhibitors
ITTO20030140U1 (it) *	2003-09-16	2005-03-17	Interfila Srl	Matita cosmetica
WO2005033092A1 (en)	2003-09-19	2005-04-14	Galileo Pharmaceuticals, Inc.	Chroman derivatives
US20050165025A1 (en) *	2004-01-22	2005-07-28	Recordati Ireland Ltd.	Combination therapy with 5HT 1A and 5HT 1B-receptor antagonists
US7951805B2 (en)	2004-09-20	2011-05-31	Xenon Pharmaceuticals Inc.	Heterocyclic derivatives and their use as mediators of stearoyl-CoA desaturase
EP2316458A1 (de)	2004-09-20	2011-05-04	Xenon Pharmaceuticals Inc.	Pyridazin-Derivate zur Verhinderung menschlicher Stearoyl-coa-desaturas
US7767677B2 (en)	2004-09-20	2010-08-03	Xenon Pharmaceuticals Inc.	Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors
EP1804799B1 (de)	2004-09-20	2013-08-21	Xenon Pharmaceuticals Inc.	Heterozyklische Derivate und ihre Verwendung als Stearoyl-Coa-Desaturase-Inhibitoren
CA2580856A1 (en)	2004-09-20	2006-03-30	Xenon Pharmaceuticals Inc.	Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
EP1799667B1 (de)	2004-09-20	2013-03-20	Xenon Pharmaceuticals Inc.	Heterozyklische derivate und ihre verwendung als therapeutische wirkstoffe
EP2289510A1 (de)	2004-09-20	2011-03-02	Xenon Pharmaceuticals Inc.	Heterozyklische Derivate zur Behandlung von durch Stearoyl-Coa-Desaturase-Enzyme verursachten Krankheiten
EP2029138A1 (de)	2005-06-03	2009-03-04	Xenon Pharmaceuticals Inc.	Aminothiazolderivate als humane stearoyl-coa desaturasehemmer
WO2008130323A1 (en) *	2007-04-23	2008-10-30	Astrazeneca Ab	Novel 8-piperazine-tetrahydronaphtalene derivatives for the treatment of pain
WO2008130321A2 (en) *	2007-04-23	2008-10-30	Astrazeneca Ab	Novel n-tetrahydronaphtalene or 5-heterocyclyl-chromane or 8-heterocyclyl-tetrahydronaphtalene derivatives for the treatment of pain
WO2008130319A2 (en) *	2007-04-23	2008-10-30	Astrazeneca Ab	Novel n-tetrahydronaphtalene or n-chromane carboxamide derivatives for the treatment of pain
SA08290245B1 (ar)	2007-04-23	2012-02-12	استرازينيكا ايه بي	مشتقات كربو كساميد جديدة من -n (8-اريل رباعي هيدرو نفثالين غير متجانس- 2- يل) أو -n (5-اريل كرومان غير متجانس -3-يل) لعلاج الألم
WO2008130322A1 (en) *	2007-04-23	2008-10-30	Astrazeneca Ab	Novel 5-heterocyclyl-chromane derivatives for the treatment of pain
TWI402072B (zh)	2010-10-19	2013-07-21	Lilly Co Eli	組織蛋白酶ｓ抑制劑化合物

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE56007T1 (de) *	1984-06-22	1990-09-15	Beecham Group Plc	Wirksame benzopyranverbindungen.
IT1190405B (it) *	1985-10-22	1988-02-16	Recordati Chem Pharm	Derivati del flavone
US5387587A (en) *	1986-12-23	1995-02-07	Merck Patent Gesellschaft Mit Beschrankter Haftung	Chroman derivatives
AU627027B2 (en)	1989-04-27	1992-08-13	Pharmacia & Upjohn Company	Substituted 3-amino chromans
US5420151A (en)	1989-12-22	1995-05-30	Aktiebolaget Astra	Chroman derivatives
SE8904361D0 (sv)	1989-12-22	1989-12-22	Astra Ab	New chroman and thiochroman derivatives
WO1997007120A1 (en) *	1995-08-11	1997-02-27	Smithkline Beecham Plc	Biphenyl(thio)amide and biphenylethan(thi)one derivatives, their preparation and their use as 5-ht1d receptor antagonists
US5849733A (en) *	1996-05-10	1998-12-15	Bristol-Myers Squibb Co.	2-thio or 2-oxo flavopiridol analogs
SE9703378D0 (sv) *	1997-09-18	1997-09-18	Astra Ab	New compounds
SE9703377D0 (sv) *	1997-09-18	1997-09-18	Astra Ab	New compounds
GB0112834D0 (en) *	2001-05-25	2001-07-18	Smithkline Beecham Plc	Medicaments
UY29896A1 (es) *	2005-11-04	2007-06-29	Astrazeneca Ab	Nuevos derivados de cromano, composiciones farmacéuticas conteniéndolos, procesos de preparación y aplicaciones
UY29892A1 (es) *	2005-11-04	2007-06-29	Astrazeneca Ab	Nuevos derivados de cromano, composiciones farmaceuticas conteniendolos, procesos de preparacion y aplicaciones

1997
- 1997-09-18 SE SE9703377A patent/SE9703377D0/xx unknown
1998
- 1998-08-27 ZA ZA987813A patent/ZA987813B/xx unknown
- 1998-09-09 TR TR2000/00736T patent/TR200000736T2/xx unknown
- 1998-09-09 HU HU0100684A patent/HUP0100684A3/hu unknown
- 1998-09-09 HR HR20000132A patent/HRP20000132A2/hr not_active Application Discontinuation
- 1998-09-09 SK SK286-2000A patent/SK2862000A3/sk unknown
- 1998-09-09 AT AT98944377T patent/ATE255098T1/de not_active IP Right Cessation
- 1998-09-09 EP EP98944377A patent/EP1025095B1/de not_active Expired - Lifetime
- 1998-09-09 EE EEP200000140A patent/EE200000140A/xx unknown
- 1998-09-09 AU AU91932/98A patent/AU734580B2/en not_active Ceased
- 1998-09-09 DE DE69820102T patent/DE69820102T2/de not_active Expired - Fee Related
- 1998-09-09 JP JP2000511761A patent/JP4150161B2/ja not_active Expired - Fee Related
- 1998-09-09 CN CN98811112A patent/CN1278810A/zh active Pending
- 1998-09-09 US US09/171,570 patent/US6479497B1/en not_active Expired - Fee Related
- 1998-09-09 BR BR9812238-0A patent/BR9812238A/pt not_active IP Right Cessation
- 1998-09-09 IL IL13507398A patent/IL135073A0/xx unknown
- 1998-09-09 KR KR1020007002823A patent/KR20010024077A/ko not_active Withdrawn
- 1998-09-09 CA CA002304037A patent/CA2304037A1/en not_active Abandoned
- 1998-09-09 PL PL98339664A patent/PL339664A1/xx not_active Application Discontinuation
- 1998-09-09 WO PCT/SE1998/001603 patent/WO1999014212A1/en not_active Ceased
- 1998-09-17 AR ARP980104636A patent/AR015449A1/es not_active Application Discontinuation
2000
- 2000-03-14 IS IS5402A patent/IS5402A/is unknown
- 2000-03-17 NO NO20001402A patent/NO20001402L/no not_active Application Discontinuation
2002
- 2002-11-01 US US10/285,743 patent/US6670359B2/en not_active Expired - Fee Related
2003
- 2003-11-13 US US10/714,577 patent/US7056921B2/en not_active Expired - Fee Related
2006
- 2006-06-05 US US11/447,589 patent/US7384943B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP1025095B1 (de)	2003-11-26
US6670359B2 (en)	2003-12-30
PL339664A1 (en)	2001-01-02
TR200000736T2 (tr)	2000-07-21
US7056921B2 (en)	2006-06-06
ZA987813B (en)	1999-03-18
SK2862000A3 (en)	2000-11-07
CA2304037A1 (en)	1999-03-25
CN1278810A (zh)	2001-01-03
DE69820102D1 (de)	2004-01-08
WO1999014212A1 (en)	1999-03-25
EE200000140A (et)	2001-02-15
IS5402A (is)	2000-03-14
NO20001402D0 (no)	2000-03-17
HUP0100684A2 (hu)	2002-05-29
IL135073A0 (en)	2001-05-20
US20030100556A1 (en)	2003-05-29
US7384943B2 (en)	2008-06-10
SE9703377D0 (sv)	1997-09-18
US20060223828A1 (en)	2006-10-05
HRP20000132A2 (en)	2001-12-31
HUP0100684A3 (en)	2002-06-28
EP1025095A1 (de)	2000-08-09
AR015449A1 (es)	2001-05-02
BR9812238A (pt)	2000-07-18
JP2001516754A (ja)	2001-10-02
DE69820102T2 (de)	2004-07-15
ATE255098T1 (de)	2003-12-15
KR20010024077A (ko)	2001-03-26
US20040157857A1 (en)	2004-08-12
US6479497B1 (en)	2002-11-12
JP4150161B2 (ja)	2008-09-17
AU734580B2 (en)	2001-06-14
AU9193298A (en)	1999-04-05

Legal Events

Date	Code	Title	Description
2003-06-10	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
SE9703377D0 (sv)	1997-09-18	New compounds
SE9702799D0 (sv)	1997-07-25	New compounds
YU40998A (sh)	1999-09-27	Derivati supstituisanog 1,2,3,4-tetrahidronaftalina
NO20004624L (no)	2000-10-30	Benzensulfonamid-derivater og deres anvendelse som medikamenter
NO20053460L (no)	2005-08-12	Nye forbindelser med selektiv inhibiterende effekt ved GSK3
DE3881472D1 (de)	1993-07-08	Heterocyclische verbindungen mit therapeutischer wirkung.
NO20001403L (no)	2000-05-18	Substituerte kromanderivater
DK0437030T3 (da)	1994-05-16	Anvendelse af 4-substituerede imidazoler til nedsættelse af det intraoculære tryk
NO20052683L (no)	2005-06-03	Nye pyridopyrimidinonforbindelser, fremgangsmate for deres fremstilling og farmasoytiske sammensetninger inneholdende dem
PT1216245E (pt)	2004-08-31	Derivados sulfonil-hidrazida farmaceuticamente activos
HUT59124A (en)	1992-04-28	Process for producing 2-(aminoalkyl)-5-(arylalkyl)-1,3-dioxane derivatives and pharmaceutical compositions comprising such derivatives as active ingredient
IL106993A (en)	1997-06-10	Benzenalkanoic acid derivatives and pharmaceutical compositions containing them
YU178391A (sh)	1994-01-20	Jedinjenja 7-acil-3(supstituisanih karbamoiloksi) cefema i postupak za njihovo dobijanje
MX9405111A (es)	1995-01-31	Nuevos derivados de (1-fenil-1-heterociclil)metanol y(1-fenil-1-heterociclil-metilamina).
FI950138A0 (fi)	1995-01-12	Uusia 4-(3-bentsofuranyyli)piperidinyyli- ja 4-(3-bentsotienyyli)piperidinyylijohdannaisia ja niitä sisältäviä farmaseuttisia koostumuksia
NZ543068A (en)	2009-07-31	Substituted 4-(alkyl-amide)-piperidine derivatives, processes for their preparation, and pharmaceutical compositions containing them
SE9002727D0 (sv)	1990-08-24	Novel cyclic ketone derivatives and pharmaceuticalcompositions containing same as well as a process for their preparation
NO20002315L (no)	2000-11-06	Nye 1-aza-2-alkyl-6-aryl-cykloalkanforbindelser, fremgangsmÕte ved deres fremstilling og farmasøytiske sammensetninger inneholdende dem
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