NO20002941L - Nye bicykliske amino-pyrazinonforbindelser, fremgangsmåte ved deres fremstilling og farmasöytiske sammensetninger inneholdende dem - Google Patents

Nye bicykliske amino-pyrazinonforbindelser, fremgangsmåte ved deres fremstilling og farmasöytiske sammensetninger inneholdende dem

Info

Publication number
NO20002941L
NO20002941L NO20002941A NO20002941A NO20002941L NO 20002941 L NO20002941 L NO 20002941L NO 20002941 A NO20002941 A NO 20002941A NO 20002941 A NO20002941 A NO 20002941A NO 20002941 L NO20002941 L NO 20002941L
Authority
NO
Norway
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
novel bicyclic
bicyclic amino
Prior art date
Application number
NO20002941A
Other languages
English (en)
Other versions
NO316650B1 (no
NO20002941D0 (no
Inventor
Guillaume De Nanteuil
Philippe Gloanec
Tony Verbeuren
Alain Rupin
Marie-Odile Vallez
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of NO20002941D0 publication Critical patent/NO20002941D0/no
Publication of NO20002941L publication Critical patent/NO20002941L/no
Publication of NO316650B1 publication Critical patent/NO316650B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO20002941A 1999-06-15 2000-06-08 Nye bicykliske amino-pyrazinonforbindelser, fremgangsmate ved deres fremstilling og farmasoytiske sammensetninger inneholdende dem NO316650B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9907538A FR2795072B1 (fr) 1999-06-15 1999-06-15 Nouveaux derives bicycliques d'amino-pyrazinones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (3)

Publication Number Publication Date
NO20002941D0 NO20002941D0 (no) 2000-06-08
NO20002941L true NO20002941L (no) 2000-12-18
NO316650B1 NO316650B1 (no) 2004-03-22

Family

ID=9546789

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20002941A NO316650B1 (no) 1999-06-15 2000-06-08 Nye bicykliske amino-pyrazinonforbindelser, fremgangsmate ved deres fremstilling og farmasoytiske sammensetninger inneholdende dem

Country Status (22)

Country Link
US (1) US6277851B1 (no)
EP (1) EP1069132B1 (no)
JP (1) JP3364472B2 (no)
KR (1) KR100456796B1 (no)
CN (1) CN1147489C (no)
AT (1) ATE251177T1 (no)
AU (1) AU766194B2 (no)
BR (1) BR0002643A (no)
CA (1) CA2312206C (no)
DE (1) DE60005609T2 (no)
DK (1) DK1069132T3 (no)
EA (1) EA003209B1 (no)
ES (1) ES2208239T3 (no)
FR (1) FR2795072B1 (no)
HU (1) HUP0002277A3 (no)
NO (1) NO316650B1 (no)
NZ (1) NZ505149A (no)
PL (1) PL199522B1 (no)
PT (1) PT1069132E (no)
SE (1) SE1069132T5 (no)
SI (1) SI1069132T1 (no)
ZA (1) ZA200003034B (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2396504A1 (en) * 2000-02-29 2001-09-07 Dupont Pharmaceuticals Company Inhibitors of hepatitis c virus ns3 protease
FR2818277B1 (fr) * 2000-12-14 2003-01-24 Servier Lab Nouveaux derives bicycliques d'amino-pyrazinones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
WO2004002405A2 (en) * 2002-06-26 2004-01-08 Bristol-Myers Squibb Company Amino-bicyclic pyrazinones and pyridinones
FR2867780B1 (fr) * 2004-03-19 2006-05-19 Servier Lab Nouveaux derives de 4-oxo-4,6,7,8-tetrahydropyrrolo (1,2-a) pyrazine-6-carboxamides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
EP2807156A1 (en) * 2012-01-27 2014-12-03 Novartis AG Aminopyridine derivatives as plasma kallikrein inhibitors
US20250122225A1 (en) * 2023-10-06 2025-04-17 Omeros Corporation Masp-2 inhibitors and methods of use

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05117276A (ja) * 1991-10-23 1993-05-14 Sumitomo Pharmaceut Co Ltd 新規な３環性キノキサリンジオン誘導体
WO1996019483A1 (en) * 1994-12-22 1996-06-27 Biochem Pharma Inc. Low molecular weight bicyclic thrombin inhibitors
WO1996030396A1 (en) * 1995-03-24 1996-10-03 Molecumetics Ltd. β-SHEET MIMETICS AND USE THEREOF AS PROTEASE INHIBITORS
EP0923372A4 (en) * 1996-02-22 2001-09-05 Merck & Co Inc INHIBITORS OF PYRIDINONE THROMBIN
AU3232597A (en) * 1996-06-18 1998-01-07 Warner-Lambert Company Pyrrolo{1,2-a}pyrazine-1,4-dione serine protease inhibitors
AU4172397A (en) * 1996-09-06 1998-03-26 Biochem Pharma Inc. Lactam inhibitors of thrombin
ATE234091T1 (de) * 1996-10-24 2003-03-15 Merck & Co Inc Thrombin inhibitoren
US5792779A (en) * 1997-02-19 1998-08-11 Merck & Co., Inc. Pyridinone thrombin inhibitors
AU740447B2 (en) * 1997-09-23 2001-11-01 Merck & Co., Inc. Thrombin inhibitors

Also Published As

Publication number Publication date
ZA200003034B (en) 2001-01-11
EA200000527A2 (ru) 2000-12-25
NO316650B1 (no) 2004-03-22
KR100456796B1 (ko) 2004-11-10
EA200000527A3 (ru) 2001-04-23
PL199522B1 (pl) 2008-09-30
AU766194B2 (en) 2003-10-09
DK1069132T3 (da) 2004-02-02
FR2795072B1 (fr) 2001-07-27
EP1069132A1 (fr) 2001-01-17
SE1069132T3 (sv) 2003-12-09
DE60005609T2 (de) 2004-08-05
PL340784A1 (en) 2000-12-18
CN1147489C (zh) 2004-04-28
JP3364472B2 (ja) 2003-01-08
HUP0002277A2 (hu) 2001-05-28
ES2208239T3 (es) 2004-06-16
CN1277198A (zh) 2000-12-20
EA003209B1 (ru) 2003-02-27
BR0002643A (pt) 2001-01-02
AU4086500A (en) 2000-12-21
DE60005609D1 (de) 2003-11-06
HK1032236A1 (en) 2001-07-13
SI1069132T1 (en) 2003-12-31
SE1069132T5 (sv) 2004-01-07
JP2001026592A (ja) 2001-01-30
ATE251177T1 (de) 2003-10-15
NO20002941D0 (no) 2000-06-08
HU0002277D0 (en) 2000-08-28
US6277851B1 (en) 2001-08-21
CA2312206A1 (fr) 2000-12-15
KR20010066846A (ko) 2001-07-11
NZ505149A (en) 2001-01-26
FR2795072A1 (fr) 2000-12-22
HUP0002277A3 (en) 2002-12-28
PT1069132E (pt) 2004-02-27
CA2312206C (fr) 2004-07-06
EP1069132B1 (fr) 2003-10-01

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