NO20003131L - Krystallinsk teriparatid - Google Patents

Krystallinsk teriparatid

Info

Publication number: NO20003131L
Authority: NO; Norway
Prior art keywords: teriparatide; crystalline; purification; pure; preparation
Prior art date: 1997-12-18

Application number

NO20003131A

Other languages

English (en)

Norwegian (no)

Other versions

NO20003131D0 (no

Inventor

Faming Zhang

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-12-18

Filing date

2000-06-16

Publication date

2000-06-16

2000-06-16 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

2000-06-16 Publication of NO20003131D0 publication Critical patent/NO20003131D0/no

2000-06-16 Publication of NO20003131L publication Critical patent/NO20003131L/no

Links

108010049264 Teriparatide Proteins 0.000 title abstract 2
OGBMKVWORPGQRR-UMXFMPSGSA-N teriparatide Chemical compound C([C@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H](N)CO)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC=1N=CNC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1N=CNC=1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)C1=CNC=N1 OGBMKVWORPGQRR-UMXFMPSGSA-N 0.000 title abstract 2
229960005460 teriparatide Drugs 0.000 title abstract 2
102000003982 Parathyroid hormone Human genes 0.000 abstract 1
108090000445 Parathyroid hormone Proteins 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
229960001319 parathyroid hormone Drugs 0.000 abstract 1
239000000199 parathyroid hormone Substances 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1
238000000746 purification Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Endocrinology (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Toxicology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Physical Education & Sports Medicine (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Steroid Compounds (AREA)

NO20003131A 1997-12-18 2000-06-16 Krystallinsk teriparatid NO20003131L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US6987597P	1997-12-18	1997-12-18
PCT/US1998/026044 WO1999031137A1 (en)	1997-12-18	1998-12-08	Crystalline teriparatide

Publications (2)

Publication Number	Publication Date
NO20003131D0 NO20003131D0 (no)	2000-06-16
NO20003131L true NO20003131L (no)	2000-06-16

Family

ID=22091750

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20003131A NO20003131L (no)	1997-12-18	2000-06-16	Krystallinsk teriparatid

Country Status (24)

Country	Link
US (1)	US6590081B1 (id)
EP (1)	EP0926158B1 (id)
JP (1)	JP2002508395A (id)
KR (1)	KR20010033268A (id)
CN (1)	CN1281467A (id)
AR (1)	AR038648A1 (id)
AT (1)	ATE245165T1 (id)
AU (1)	AU748271B2 (id)
BR (1)	BR9813740A (id)
CA (1)	CA2315103A1 (id)
DE (1)	DE69816409T2 (id)
DK (1)	DK0926158T3 (id)
EA (1)	EA200000672A1 (id)
ES (1)	ES2202729T3 (id)
HU (1)	HUP0100075A2 (id)
ID (1)	ID25660A (id)
IL (1)	IL136824A0 (id)
NO (1)	NO20003131L (id)
PE (1)	PE20000056A1 (id)
PL (1)	PL341209A1 (id)
PT (1)	PT926158E (id)
TR (1)	TR200002179T2 (id)
WO (1)	WO1999031137A1 (id)
ZA (1)	ZA9811407B (id)

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US7247609B2 (en)	2001-12-18	2007-07-24	Universitat Zurich	Growth factor modified protein matrices for tissue engineering
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RU2357750C2 (ru)	2002-12-31	2009-06-10	Элтус Фармасьютикалз Инк.	Кристаллы человеческого гормона роста и способы их получения
US8088734B2 (en)	2003-01-21	2012-01-03	Unigene Laboratories Inc.	Oral delivery of peptides
US7429378B2 (en) *	2003-05-13	2008-09-30	Depuy Spine, Inc.	Transdiscal administration of high affinity anti-MMP inhibitors
US7344716B2 (en)	2003-05-13	2008-03-18	Depuy Spine, Inc.	Transdiscal administration of specific inhibitors of pro-inflammatory cytokines
US8273347B2 (en)	2003-05-13	2012-09-25	Depuy Spine, Inc.	Autologous treatment of degenerated disc with cells
US7553827B2 (en) *	2003-08-13	2009-06-30	Depuy Spine, Inc.	Transdiscal administration of cycline compounds
US20040229878A1 (en) *	2003-05-13	2004-11-18	Depuy Spine, Inc.	Transdiscal administration of specific inhibitors of P38 kinase
US8361467B2 (en) *	2003-07-30	2013-01-29	Depuy Spine, Inc.	Trans-capsular administration of high specificity cytokine inhibitors into orthopedic joints
US8895540B2 (en)	2003-11-26	2014-11-25	DePuy Synthes Products, LLC	Local intraosseous administration of bone forming agents and anti-resorptive agents, and devices therefor
US20060127320A1 (en) *	2004-05-10	2006-06-15	Nastech Pharmaceutical Company Inc.	Method of delivering parathyroid hormone to a human
CA2567056A1 (en) *	2004-05-10	2005-12-08	Nastech Pharmaceutical Company Inc.	Compositions and methods for enhanced mucosal delivery of parathyroid hormone
US20060052305A1 (en) *	2004-05-10	2006-03-09	Nastech Pharmaceutical Company Inc.	Method of treating osteoporosis using intranasal parathyroid hormone
US7556821B2 (en)	2004-05-13	2009-07-07	Alza Corporation	Apparatus and method for transdermal delivery of parathyroid hormone agents
US8575101B2 (en)	2005-01-06	2013-11-05	Kuros Biosurgery Ag	Supplemented matrices for the repair of bone fractures
WO2006073711A2 (en)	2005-01-06	2006-07-13	Kuros Biosurgery Ag	Use of a matrix comprising a contrast agent in soft tissues
WO2006081279A2 (en)	2005-01-25	2006-08-03	Microchips, Inc.	Control of drug release by transient modification of local microenvironments
US7691105B2 (en)	2005-09-26	2010-04-06	Depuy Spine, Inc.	Tissue augmentation, stabilization and regeneration technique
US20070088436A1 (en)	2005-09-29	2007-04-19	Matthew Parsons	Methods and devices for stenting or tamping a fractured vertebral body
US20070173447A1 (en) *	2005-10-25	2007-07-26	Nastech Pharmaceutical Company Inc.	Method for treating osteoporosis by intranasal delivery of teriparatide with an anti-resorptive agent
CA2628945A1 (en) *	2005-11-10	2007-05-24	Board Of Control Of Michigan Technological University	Black bear parathyroid hormone and methods of using black bear parathyroid hormone
US20080051332A1 (en) *	2005-11-18	2008-02-28	Nastech Pharmaceutical Company Inc.	Method of modulating hematopoietic stem cells and treating hematologic diseases using intranasal parathyroid hormone
US20070168041A1 (en) *	2006-01-17	2007-07-19	Sudhakar Kadiyala	Method and instruments for intervertebral disc augmentation through a pedicular approach
DK2136850T3 (da)	2007-04-13	2012-04-10	Kuros Biosurgery Ag	Polymervævforsegling
US8298789B2 (en) *	2007-08-09	2012-10-30	Usv Limited	Orthogonal process for purification of recombinant human parathyroid hormone (rhPTH) (1-34)
TW200930343A (en) *	2007-09-21	2009-07-16	Organon Nv	Drug delivery system
US8241363B2 (en)	2007-12-19	2012-08-14	Depuy Spine, Inc.	Expandable corpectomy spinal fusion cage
US8241294B2 (en)	2007-12-19	2012-08-14	Depuy Spine, Inc.	Instruments for expandable corpectomy spinal fusion cage
US20090162351A1 (en) *	2007-12-21	2009-06-25	Depuy Spine, Inc.	Transdiscal administration of inhibitors of p38 MAP kinase
US8986696B2 (en) *	2007-12-21	2015-03-24	Depuy Mitek, Inc.	Trans-capsular administration of p38 map kinase inhibitors into orthopedic joints
WO2009083544A2 (en)	2007-12-28	2009-07-09	Kuros Biosurgery Ag	Pdgf fusion proteins incorporated into fibrin foams
US8876905B2 (en)	2009-04-29	2014-11-04	DePuy Synthes Products, LLC	Minimally invasive corpectomy cage and instrument
BR112012013725A2 (pt)	2009-12-07	2017-01-10	Univ Michigan Tech	paratormônio de urso preto e métodos de usar o paratormônio de uso preto.
US8865220B2 (en)	2010-06-14	2014-10-21	Kaohsiung Medical University	Method for controlled release of parathyroid hormone from encapsulated poly(lactic-glycolic)acid microspheres
EP2686027B1 (en)	2011-03-16	2021-05-05	Kuros Biosurgery AG	Pharmaceutical formulation for use in spinal fusion
CN102731643A (zh) *	2012-06-26	2012-10-17	深圳翰宇药业股份有限公司	一种治疗骨质疏松多肽的制备方法
WO2015086489A1 (en)	2013-12-11	2015-06-18	Merck Sharp & Dohme B.V.	Drug delivery system for delivery of anti-virals
US10413504B2 (en)	2013-12-11	2019-09-17	Merck Sharp & Dohme Corp.	Intravaginal ring drug delivery system
CN104910269B (zh) *	2015-06-02	2018-08-17	成都圣诺生物科技股份有限公司	一种合成特立帕肽的方法
US20200289621A1 (en) *	2017-09-22	2020-09-17	Asahi Kasei Pharma Corporation	Teriparatide-containing liquid pharmaceutical composition having excellent stability

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Publication number	Priority date	Publication date	Assignee	Title
JPS62106000A (ja)	1985-10-30	1987-05-16	Fujitsu Ltd	生体高分子結晶自動作製装置
ATE138685T1 (de) *	1987-10-20	1996-06-15	Michael F Holick	Regulierung der zellenproliferation und differenzierung mittels peptiden
WO1993007311A1 (en) *	1991-10-09	1993-04-15	Schering Corporation	Crystal forming device and automated crystallization system
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US5496801A (en) *	1993-12-23	1996-03-05	Allelix Biopharmaceuticals Inc.	Parathyroid hormone formulation
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CA2178894A1 (en)	1995-06-15	1996-12-16	Tsunehiko Fukuda	Parathyroid hormone derivatives and their use

1998
- 1998-12-08 PL PL98341209A patent/PL341209A1/xx not_active Application Discontinuation
- 1998-12-08 EA EA200000672A patent/EA200000672A1/ru unknown
- 1998-12-08 TR TR2000/02179T patent/TR200002179T2/xx unknown
- 1998-12-08 WO PCT/US1998/026044 patent/WO1999031137A1/en not_active Ceased
- 1998-12-08 IL IL13682498A patent/IL136824A0/xx unknown
- 1998-12-08 BR BR9813740-9A patent/BR9813740A/pt not_active IP Right Cessation
- 1998-12-08 CA CA002315103A patent/CA2315103A1/en not_active Abandoned
- 1998-12-08 AU AU16326/99A patent/AU748271B2/en not_active Ceased
- 1998-12-08 CN CN98812144A patent/CN1281467A/zh active Pending
- 1998-12-08 ID IDW20001360A patent/ID25660A/id unknown
- 1998-12-08 HU HU0100075A patent/HUP0100075A2/hu unknown
- 1998-12-08 JP JP2000539060A patent/JP2002508395A/ja not_active Withdrawn
- 1998-12-08 KR KR1020007006705A patent/KR20010033268A/ko not_active Withdrawn
- 1998-12-08 US US09/555,447 patent/US6590081B1/en not_active Expired - Fee Related
- 1998-12-11 ZA ZA9811407A patent/ZA9811407B/xx unknown
- 1998-12-16 DE DE69816409T patent/DE69816409T2/de not_active Expired - Fee Related
- 1998-12-16 ES ES98123878T patent/ES2202729T3/es not_active Expired - Lifetime
- 1998-12-16 AR ARP980106420A patent/AR038648A1/es unknown
- 1998-12-16 EP EP98123878A patent/EP0926158B1/en not_active Expired - Lifetime
- 1998-12-16 PT PT98123878T patent/PT926158E/pt unknown
- 1998-12-16 DK DK98123878T patent/DK0926158T3/da active
- 1998-12-16 AT AT98123878T patent/ATE245165T1/de not_active IP Right Cessation
- 1998-12-17 PE PE1998001242A patent/PE20000056A1/es not_active Application Discontinuation
2000
- 2000-06-16 NO NO20003131A patent/NO20003131L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
CN1281467A (zh)	2001-01-24
IL136824A0 (en)	2001-06-14
KR20010033268A (ko)	2001-04-25
ES2202729T3 (es)	2004-04-01
BR9813740A (pt)	2000-10-10
AU748271B2 (en)	2002-05-30
PT926158E (pt)	2003-11-28
PL341209A1 (en)	2001-03-26
EP0926158A1 (en)	1999-06-30
AU1632699A (en)	1999-07-05
EA200000672A1 (ru)	2000-12-25
EP0926158B1 (en)	2003-07-16
ATE245165T1 (de)	2003-08-15
ID25660A (id)	2000-10-19
CA2315103A1 (en)	1999-06-24
JP2002508395A (ja)	2002-03-19
HUP0100075A2 (hu)	2001-05-28
WO1999031137A1 (en)	1999-06-24
US6590081B1 (en)	2003-07-08
NO20003131D0 (no)	2000-06-16
DE69816409T2 (de)	2004-06-09
PE20000056A1 (es)	2000-02-08
AR038648A1 (es)	2005-01-26
DK0926158T3 (da)	2003-11-10
DE69816409D1 (de)	2003-08-21
TR200002179T2 (tr)	2001-07-23
ZA9811407B (en)	2000-07-13

Legal Events

Date	Code	Title	Description
2003-09-01	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
NO20003131L (no)	2000-06-16	Krystallinsk teriparatid
DK0813525T3 (da)	2004-02-16	Benzamidinderivater, deres fremstilling og anvendelse som antikoagulanter
NO20030374L (no)	2003-01-24	Syklopentanoindoler, preparater som inneholder slike forbindelser og behandlingsfremgangsmåter
DK0741694T3 (da)	2003-04-22	Phenyleddikesyrederivater, fremgangsmåder og mellemprodukter til deres fremstilling og midler indeholdende disse
DK0876332T3 (da)	2001-09-03	Phenyleddikesyrederivater, fremgangsmåde og mellemprodukter til deres fremstilling og midler indeholdende disse
DK1017670T3 (da)	2002-12-16	Benzamidoximderivater, mellemprodukter og fremgangsmåder til deres fremstilling og deres anvendelse som fungicider
FI934622A7 (fi)	1994-04-21	Menetelmä amylaasin puhdistamiseksi, näin saatu puhdistettu amylaasi ja puhdistetun amylaasin käytöt
ES2191292T3 (es)	2003-09-01	Compuestos antivirales poliaromaticos.
DK1036794T3 (da)	2003-12-22	2-Aryl-8-oxodihydropurinderivater, fremgangsmåde til fremstilling af samme, medicinske præparater indeholdende samme og mellemprodukter deraf
DK1097173T3 (da)	2008-09-01	Anvendelse af peptider af IL-2 og derivater deraf som terapeutiske midler
DK1140018T3 (da)	2004-02-02	Polyol/olie-suspensioner til vedvarende frigørelse af proteiner
DK27087D0 (da)	1987-01-19	Genoprettelse af tilretning, dvs. framing i et kommunikationssystem
NO995928L (no)	2000-02-09	Alfa-1-antitrypsin-preparater samt fremgangsmåte ved fremstilling derav
ES2158034T3 (es)	2001-09-01	Derivado de benzotiepina opticamente activo, su preparacion y uso.
DK1154986T3 (da)	2004-10-18	Fremgangsmåde til fremstilling af iopamidol
ATE202483T1 (de)	2001-07-15	Immuntolerante prothrombinkomplex-präparation
DK0775159T3 (da)	2002-02-11	Ny fremgangsmåde til fremstilling af biologisk aktivt dimert protein
DK1427286T3 (da)	2010-09-27	Fremgangsmåde til udtynding af frugt
ES2195483T3 (es)	2003-12-01	Concentrado acuoso para suspension, que contiene tidiazuron y etefon.
DK1303267T3 (da)	2004-06-14	System til dermal tilförsel af aminolevulinsyre
ES2014546A6 (es)	1990-07-16	Procedimiento para la obtencion de fctor activador de neutrofilos.
NO990914L (no)	1999-02-25	Amorfe benzotiofener, fremgangsmÕter for fremstilling og fremgangsmÕter for anvendelse
NZ503372A (en)	2002-08-28	Chemical supplementation of bone by exposing bone to a therapeutic compound and applying a potential difference across the bone or tissue
FI945164A0 (fi)	1994-11-02	Biologisesti aktiivisesti ureidojohdannaiset, jotka ovat käyttökelpoisia antimetastaattisina aineina
DK1068209T3 (da)	2005-11-14	Fremgangsmåde til fremstilling af purinderivater og deres mellemprodukter