NO20003335L - Fremgangsmåte for selektiv separering og rensing av eikosapentaen- og dokosaheksaensyrer eller deres estere - Google Patents

Fremgangsmåte for selektiv separering og rensing av eikosapentaen- og dokosaheksaensyrer eller deres estere

Info

Publication number: NO20003335L
Authority: NO; Norway
Prior art keywords: esters; eicosapentaene; purification; flowing; diatomaceous earth
Prior art date: 1999-06-28

Application number

NO20003335A

Other languages

English (en)

Other versions

NO20003335D0 (no

NO321273B1 (no

Inventor

Satoshi Kiyohara

Shiro Fujita

Original Assignee

Nisshin Flour Milling Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-06-28

Filing date

2000-06-26

Publication date

2000-12-29

2000-06-26 Application filed by Nisshin Flour Milling Co filed Critical Nisshin Flour Milling Co

2000-06-26 Publication of NO20003335D0 publication Critical patent/NO20003335D0/no

2000-12-29 Publication of NO20003335L publication Critical patent/NO20003335L/no

2006-04-10 Publication of NO321273B1 publication Critical patent/NO321273B1/no

Links

DVSZKTAMJJTWFG-UHFFFAOYSA-N docosa-2,4,6,8,10,12-hexaenoic acid Chemical class CCCCCCCCCC=CC=CC=CC=CC=CC=CC(O)=O DVSZKTAMJJTWFG-UHFFFAOYSA-N 0.000 title abstract 2
235000020669 docosahexaenoic acid Nutrition 0.000 title abstract 2
150000002148 esters Chemical class 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
238000000746 purification Methods 0.000 title 1
238000000926 separation method Methods 0.000 title 1
239000005909 Kieselgur Substances 0.000 abstract 3
VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 3
239000000203 mixture Substances 0.000 abstract 2
GGCZERPQGJTIQP-UHFFFAOYSA-N sodium;9,10-dioxoanthracene-2-sulfonic acid Chemical compound [Na+].C1=CC=C2C(=O)C3=CC(S(=O)(=O)O)=CC=C3C(=O)C2=C1 GGCZERPQGJTIQP-UHFFFAOYSA-N 0.000 abstract 2
239000002904 solvent Substances 0.000 abstract 2
235000021122 unsaturated fatty acids Nutrition 0.000 abstract 2
150000004670 unsaturated fatty acids Chemical class 0.000 abstract 2
BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical class [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 abstract 1
239000012736 aqueous medium Substances 0.000 abstract 1
235000020673 eicosapentaenoic acid Nutrition 0.000 abstract 1
229910052709 silver Inorganic materials 0.000 abstract 1
239000004332 silver Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/47—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/48—Separation; Purification; Stabilisation; Use of additives
- C07C67/56—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Oil, Petroleum & Natural Gas (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Fats And Perfumes (AREA)

NO20003335A 1999-06-28 2000-06-26 Fremgangsmate for selektiv separering og rensing av eikosapentaen- og dokosaheksaensyrer eller deres estere NO321273B1 (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP18140799		1999-06-28

Publications (3)

Publication Number	Publication Date
NO20003335D0 NO20003335D0 (no)	2000-06-26
NO20003335L true NO20003335L (no)	2000-12-29
NO321273B1 NO321273B1 (no)	2006-04-10

Family

ID=16100230

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20003335A NO321273B1 (no)	1999-06-28	2000-06-26	Fremgangsmate for selektiv separering og rensing av eikosapentaen- og dokosaheksaensyrer eller deres estere

Country Status (7)

Country	Link
US (1)	US6313330B1 (no)
EP (1)	EP1065196B1 (no)
AT (1)	ATE241584T1 (no)
CA (1)	CA2311974A1 (no)
DE (1)	DE60002952T2 (no)
DK (1)	DK1065196T3 (no)
NO (1)	NO321273B1 (no)

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JP4839454B2 (ja)	2003-12-30	2011-12-21	ディーエスエムアイピーアセッツビー．ブイ．	脱気方法
KR20130101596A (ko) *	2005-07-08	2013-09-13	마텍 바이오싸이언스스 코포레이션	치매 및 치매-전단계와 관련된 용태의 치료를 위한 다중불포화 지방산
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JP5503856B2 (ja) *	2008-09-10	2014-05-28	キユーピー株式会社	高度不飽和脂肪酸誘導体の取得方法
CN102438468B (zh)	2009-04-17	2014-06-04	纳塔克制药有限公司	富含低含量植烷酸的ω-3脂肪酸的组合物
CN107233337A (zh)	2009-04-29	2017-10-10	阿马里纳药物爱尔兰有限公司	含有epa和心血管剂的药物组合物以及使用其的方法
MX377553B (es)	2009-04-29	2025-03-10	Amarin Pharma Inc	Composicion farmaceutica estable y metodos de uso de la misma.
BRPI1011883A2 (pt)	2009-06-15	2016-09-13	Amarin Pharma Inc	uso de composições para redução de triglicerídeos sem elevar os níveis de o ldl-c em um paciente sob o tratamento concomitante com estatina
NZ599061A (en)	2009-09-23	2014-05-30	Amarin Pharmaceuticals Ie Ltd	Pharmaceutical composition comprising omega-3 fatty acid and hydroxy-derivative of a statin and methods of using same
US9321715B2 (en)	2009-12-30	2016-04-26	Basf Pharma (Callanish) Limited	Simulated moving bed chromatographic separation process
US11712429B2 (en)	2010-11-29	2023-08-01	Amarin Pharmaceuticals Ireland Limited	Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity
NZ744990A (en)	2010-11-29	2019-10-25	Amarin Pharmaceuticals Ie Ltd	Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity
GB201111601D0 (en)	2011-07-06	2011-08-24	Equateq Ltd	New process
GB201111589D0 (en)	2011-07-06	2011-08-24	Equateq Ltd	New modified process
GB201111591D0 (en)	2011-07-06	2011-08-24	Equateq Ltd	Further new process
GB201111595D0 (en)	2011-07-06	2011-08-24	Equateq Ltd	Improved process
GB201111594D0 (en)	2011-07-06	2011-08-24	Equateq Ltd	New improved process
US11291643B2 (en)	2011-11-07	2022-04-05	Amarin Pharmaceuticals Ireland Limited	Methods of treating hypertriglyceridemia
WO2013070735A1 (en)	2011-11-07	2013-05-16	Amarin Pharmaceuticals Ireland Limited	Methods of treating hypertriglyceridemia
EP2800469B1 (en)	2012-01-06	2021-08-25	Amarin Pharmaceuticals Ireland Limited	Compositions and methods for lowering levels of high-sensitivity (hs-crp) in a subject
US9603826B2 (en)	2012-06-29	2017-03-28	Amarin Pharmaceuticals Ireland Limited	Methods of reducing the risk of a cardiovascular event in a subject on statin therapy
WO2014074552A2 (en)	2012-11-06	2014-05-15	Amarin Pharmaceuticals Ireland Limited	Compositions and methods for lowering triglycerides without raising ldl-c levels in a subject on concomitant statin therapy
US20140187633A1 (en)	2012-12-31	2014-07-03	Amarin Pharmaceuticals Ireland Limited	Methods of treating or preventing nonalcoholic steatohepatitis and/or primary biliary cirrhosis
US9814733B2 (en)	2012-12-31	2017-11-14	A,arin Pharmaceuticals Ireland Limited	Compositions comprising EPA and obeticholic acid and methods of use thereof
GB201300354D0 (en)	2013-01-09	2013-02-20	Basf Pharma Callanish Ltd	Multi-step separation process
US9452151B2 (en)	2013-02-06	2016-09-27	Amarin Pharmaceuticals Ireland Limited	Methods of reducing apolipoprotein C-III
US9624492B2 (en)	2013-02-13	2017-04-18	Amarin Pharmaceuticals Ireland Limited	Compositions comprising eicosapentaenoic acid and mipomersen and methods of use thereof
US9662307B2 (en)	2013-02-19	2017-05-30	The Regents Of The University Of Colorado	Compositions comprising eicosapentaenoic acid and a hydroxyl compound and methods of use thereof
US9283201B2 (en)	2013-03-14	2016-03-15	Amarin Pharmaceuticals Ireland Limited	Compositions and methods for treating or preventing obesity in a subject in need thereof
US20140271841A1 (en)	2013-03-15	2014-09-18	Amarin Pharmaceuticals Ireland Limited	Pharmaceutical composition comprising eicosapentaenoic acid and derivatives thereof and a statin
US9428711B2 (en)	2013-05-07	2016-08-30	Groupe Novasep	Chromatographic process for the production of highly purified polyunsaturated fatty acids
US8802880B1 (en)	2013-05-07	2014-08-12	Group Novasep	Chromatographic process for the production of highly purified polyunsaturated fatty acids
US10966968B2 (en)	2013-06-06	2021-04-06	Amarin Pharmaceuticals Ireland Limited	Co-administration of rosiglitazone and eicosapentaenoic acid or a derivative thereof
US20150065572A1 (en)	2013-09-04	2015-03-05	Amarin Pharmaceuticals Ireland Limited	Methods of treating or preventing prostate cancer
US9585859B2 (en)	2013-10-10	2017-03-07	Amarin Pharmaceuticals Ireland Limited	Compositions and methods for lowering triglycerides without raising LDL-C levels in a subject on concomitant statin therapy
CN103962091B (zh) *	2013-11-28	2017-01-25	大连工业大学	一种银离子改性氨基硅胶分离epa和dha的方法
EP2883860B1 (fr)	2013-12-11	2016-08-24	Novasep Process	Procédé chromatographique de production d'acides gras polyinsaturés
JP6303017B2 (ja)	2014-01-07	2018-03-28	ノヴァセププロセスＮｏｖａｓｅｐＰｒｏｃｅｓｓ	芳香族アミノ酸を精製する方法
US10561631B2 (en)	2014-06-11	2020-02-18	Amarin Pharmaceuticals Ireland Limited	Methods of reducing RLP-C
WO2015195662A1 (en)	2014-06-16	2015-12-23	Amarin Pharmaceuticals Ireland Limited	Methods of reducing or preventing oxidation of small dense ldl or membrane polyunsaturated fatty acids
US10406130B2 (en)	2016-03-15	2019-09-10	Amarin Pharmaceuticals Ireland Limited	Methods of reducing or preventing oxidation of small dense LDL or membrane polyunsaturated fatty acids
US10966951B2 (en)	2017-05-19	2021-04-06	Amarin Pharmaceuticals Ireland Limited	Compositions and methods for lowering triglycerides in a subject having reduced kidney function
US11058661B2 (en)	2018-03-02	2021-07-13	Amarin Pharmaceuticals Ireland Limited	Compositions and methods for lowering triglycerides in a subject on concomitant statin therapy and having hsCRP levels of at least about 2 mg/L
MA50490A (fr)	2018-09-24	2020-09-02	Amarin Pharmaceuticals Ie Ltd	Procédés de réduction du risque d'événements cardiovasculaires chez un sujet
CN113574154B (zh) *	2019-03-26	2025-05-16	日清药业股份有限公司	含二十碳五烯酸烷基酯的组合物的制造方法
CN109912403A (zh) *	2019-04-18	2019-06-21	南京市第一医院	一种Omega-3制备大电导钙激活钾通道开放剂的方法
CA3160676A1 (en)	2019-11-12	2021-05-20	Amarin Pharmaceuticals Ireland Limited	Methods of reducing the risk of cardiovascular events in a subject with atrial fibrillation and/or atrial flutter
US11986452B2 (en)	2021-04-21	2024-05-21	Amarin Pharmaceuticals Ireland Limited	Methods of reducing the risk of heart failure

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EP0347509A1 (en) *	1988-06-21	1989-12-27	Century Laboratories Inc.	A process of extraction and purification of polyunsaturated fatty acids from natural sources
JPH028298A (ja) *	1988-06-17	1990-01-11	Agency Of Ind Science & Technol	イカ内臓からドコサヘキサエン酸及びエイコサペンタエン酸を選択的に分離精製する方法
JPH07242895A (ja) *	1993-03-16	1995-09-19	Ikeda Shiyotsuken Kk	高純度エイコサペンタエン酸又はその低級アルコールエステルの分離精製法
JPH09151390A (ja) *	1995-11-30	1997-06-10	Bizen Kasei Kk	高度不飽和脂肪酸及びその誘導体の精製方法
JPH10310551A (ja) *	1997-05-12	1998-11-24	Nippon Wax Polymer Kaihatsu Kenkyusho:Kk	エイコサペンタエン酸又はそのエステルの精製方法

2000
- 2000-06-19 CA CA002311974A patent/CA2311974A1/en not_active Abandoned
- 2000-06-21 AT AT00113020T patent/ATE241584T1/de not_active IP Right Cessation
- 2000-06-21 DK DK00113020T patent/DK1065196T3/da active
- 2000-06-21 EP EP00113020A patent/EP1065196B1/en not_active Expired - Lifetime
- 2000-06-21 DE DE60002952T patent/DE60002952T2/de not_active Expired - Fee Related
- 2000-06-26 NO NO20003335A patent/NO321273B1/no unknown
- 2000-06-28 US US09/604,766 patent/US6313330B1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DE60002952T2 (de)	2004-03-11
DK1065196T3 (da)	2003-09-22
ATE241584T1 (de)	2003-06-15
NO20003335D0 (no)	2000-06-26
EP1065196A1 (en)	2001-01-03
CA2311974A1 (en)	2000-12-28
DE60002952D1 (de)	2003-07-03
NO321273B1 (no)	2006-04-10
US6313330B1 (en)	2001-11-06
EP1065196B1 (en)	2003-05-28

Publication	Publication Date	Title
NO20003335D0 (no)	2000-06-26	FremgangsmÕte for selektiv separering og rensing av eikosapentaen- og dokosaheksaensyrer eller deres estere
JP5951764B2 (ja)	2016-07-13	魚油から高純度のｅｐａを生成するためのｓｍｂ方法
ES2459951T3 (es)	2014-05-13	Proceso de separación cromatográfico de lecho móvil simulado para la purificación de ácidos grasos poliinsaturados
JP5946833B2 (ja)	2016-07-06	ω３脂肪酸を濃縮する方法
JP5990580B2 (ja)	2016-09-14	新規なｓｍｂ方法
IS5133A (is)	1999-07-26	Hreinsun á fjölómettuðum fitusýruglýseríðum
DK1106602T3 (da)	2008-11-03	Kromatografisk simulated moving bed-oprensning af aminosyrer
DK0658164T3 (da)	2001-06-18	Fremgangsmåde til chromatografisk oprensning og adskillelse af nukleinsyreblandinger
JP2014518312A (ja)	2014-07-28	Ｓｍｂ方法
ES2097047T3 (es)	1997-03-16	Procedimientos para el fraccionamiento cromatografico de acidos grasos y sus derivados.
JP2003500082A (ja)	2003-01-07	蒸留−酵素的エステル交換の組合せによるポリ不飽和脂肪酸エステルの濃縮及び精製
MY120051A (en)	2005-08-30	Process for purification of (meth)acrylic acid
Lembke	2012	Production techniques for omega-3 concentrates
CN101830956A (zh)	2010-09-15	猪胆膏或下脚料中鹅去氧胆酸的分离纯化制备方法
JP6467426B2 (ja)	2019-02-13	クロマトグラフィ法による脂肪酸の精製
EP3305754B1 (en)	2021-11-10	Process for producing highly unsaturated fatty acid of high purity in high yield
RU2698720C1 (ru)	2019-08-29	Способ получения докозагексаеновой кислоты
ES8704186A1 (es)	1987-03-16	Procedimiento para aislar y purificar x-interferones plasmidogenos.
DE50010982D1 (de)	2005-09-22	Verfahren zur herstellung von spezifikationsgerechtem phthalsäureanhydrid
NO891069L (no)	1989-09-15	Fremgangsmaate for rensing av uren alfa-l-aspartyl-l-fenylalaninmethylester (alfa-apm).
ES2289898B1 (es)	2008-12-16	Metodo rapido y biocompatible de extraccion, saponificacion y concentracion de acidos grasos poliinsaturados (pufas) por diferencias de solubilidad a partir de biomasa.
JPS5786254A (en)	1982-05-29	Healthful food
JPH01139548A (ja)	1989-06-01	高度不飽和脂肪酸トリグリセリド及びエステルの精製方法
JP2015030685A (ja)	2015-02-16	逆相カラムを用いる擬似移動層クロマトグラフィーによる脂溶性物質の分離法およびそのための装置
Gyoung et al.	2004	Purification of Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) Esters from Squid Oil by Silver Ion Chromatography