NO20004056L - Farmasøytisk preparat som omfatter en kombinasjon av metformin og fibrat, og dets anvendelse til fremstilling av medisiner beregnet til Õ redusere hyperglykemi - Google Patents

Farmasøytisk preparat som omfatter en kombinasjon av metformin og fibrat, og dets anvendelse til fremstilling av medisiner beregnet til Õ redusere hyperglykemi

Info

Publication number
NO20004056L
NO20004056L NO20004056A NO20004056A NO20004056L NO 20004056 L NO20004056 L NO 20004056L NO 20004056 A NO20004056 A NO 20004056A NO 20004056 A NO20004056 A NO 20004056A NO 20004056 L NO20004056 L NO 20004056L
Authority
NO
Norway
Prior art keywords
fibrate
metformin
manufacture
combination
pharmaceutical composition
Prior art date
Application number
NO20004056A
Other languages
English (en)
Other versions
NO20004056D0 (no
NO328314B1 (no
Inventor
Yves Bonhomme
Philippe Briet
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of NO20004056L publication Critical patent/NO20004056L/no
Publication of NO20004056D0 publication Critical patent/NO20004056D0/no
Publication of NO328314B1 publication Critical patent/NO328314B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO20004056A 1998-02-12 2000-08-11 Farmasoytisk preparat som omfatter en kombinasjon av metformin og fibrat, og dets anvendelse til fremstilling av medisiner beregnet til a redusere hyperglykemi NO328314B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9801709A FR2774591B1 (fr) 1998-02-12 1998-02-12 Composition pharmaceutique comprenant l'association metformine et fibrate et son utilisation pour la preparation de medicaments destines a reduire l'hyperglycemie
PCT/EP1999/000614 WO1999040904A2 (en) 1998-02-12 1999-01-30 Pharmaceutical composition comprising a combination of metformin and fibrate, and its use for the treatment of hyperglycemia

Publications (3)

Publication Number Publication Date
NO20004056L true NO20004056L (no) 2000-08-11
NO20004056D0 NO20004056D0 (no) 2000-08-11
NO328314B1 NO328314B1 (no) 2010-01-25

Family

ID=9522912

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20004056A NO328314B1 (no) 1998-02-12 2000-08-11 Farmasoytisk preparat som omfatter en kombinasjon av metformin og fibrat, og dets anvendelse til fremstilling av medisiner beregnet til a redusere hyperglykemi

Country Status (27)

Country Link
US (1) US6372790B1 (no)
EP (1) EP1054665B1 (no)
JP (1) JP4767411B2 (no)
KR (1) KR100567608B1 (no)
CN (1) CN1151785C (no)
AR (1) AR018286A1 (no)
AT (1) ATE204754T1 (no)
AU (1) AU746821B2 (no)
BR (1) BRPI9907866B8 (no)
CA (1) CA2320039C (no)
CZ (1) CZ290101B6 (no)
DE (1) DE69900249T2 (no)
DK (1) DK1054665T3 (no)
ES (1) ES2162517T3 (no)
FR (1) FR2774591B1 (no)
HU (1) HU224619B1 (no)
ID (1) ID26254A (no)
MY (1) MY118164A (no)
NO (1) NO328314B1 (no)
PL (1) PL196874B1 (no)
PT (1) PT1054665E (no)
RU (1) RU2207850C2 (no)
SK (1) SK283212B6 (no)
TW (1) TW518222B (no)
UA (1) UA70315C2 (no)
WO (1) WO1999040904A2 (no)
ZA (1) ZA991077B (no)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU738804B2 (en) * 1997-12-08 2001-09-27 Bristol-Myers Squibb Company Novel salts of metformin and method
US6982281B1 (en) 2000-11-17 2006-01-03 Lipocine Inc Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs
FR2796551B1 (fr) * 1999-07-23 2003-07-25 Lipha Nouveaux sels de metformine, leur procede d'obtention et les compositions pharmaceutiques en renfermant
FR2796940B1 (fr) * 1999-07-26 2005-04-08 Lipha Nouveaux sels de metformine, leur procede d'obtention et les compositions pharmaceutiques en renfermant
US6586438B2 (en) 1999-11-03 2003-07-01 Bristol-Myers Squibb Co. Antidiabetic formulation and method
US7151191B2 (en) * 2000-01-13 2006-12-19 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6531158B1 (en) * 2000-08-09 2003-03-11 Impax Laboratories, Inc. Drug delivery system for enhanced bioavailability of hydrophobic active ingredients
JP4829411B2 (ja) * 2001-02-23 2011-12-07 キッセイ薬品工業株式会社 Ｃ型慢性肝炎治療剤
GB0119480D0 (en) 2001-08-09 2001-10-03 Jagotec Ag Novel compositions
US8911781B2 (en) 2002-06-17 2014-12-16 Inventia Healthcare Private Limited Process of manufacture of novel drug delivery system: multilayer tablet composition of thiazolidinedione and biguanides
EP1424070A1 (en) * 2002-11-28 2004-06-02 Fournier Laboratories Ireland Limited Combination of a PPAR alpha agonist and metformin for decreasing the serum triglycerides
JP2006511525A (ja) 2002-12-13 2006-04-06 ヤゴテック アーゲー ナノ粒子状スピロノラクトン局所製剤
CN1771040B (zh) * 2003-02-07 2010-06-16 味之素株式会社 糖尿病治疗药
FR2851734B1 (fr) * 2003-02-28 2006-06-09 Galenix Innovations Procede pour la fabrication d'une composition pharmaceutique sous la forme de comprimes contenant un fibrate et comprimes obtenus selon le procede
FR2858556B1 (fr) * 2003-08-06 2006-03-10 Galenix Innovations Composition pharmaceutique solide dispersible et/ou orodispersible non pelliculee contenant au moins le principe actif metformine, et procede de preparation
RU2241449C1 (ru) * 2003-09-25 2004-12-10 Открытое акционерное общество "Химико-фармацевтический комбинат "Акрихин" Фармацевтическая композиция для лечения диабета (варианты)
US8062664B2 (en) * 2003-11-12 2011-11-22 Abbott Laboratories Process for preparing formulations of lipid-regulating drugs
SG149814A1 (en) * 2003-12-19 2009-02-27 Omega Bio Pharma Ip3 Ltd Compositions and methods for treating diabetes
EP1559419A1 (en) * 2004-01-23 2005-08-03 Fournier Laboratories Ireland Limited Pharmaceutical formulations comprising metformin and a fibrate, and processes for their obtention
US20070197602A1 (en) * 2004-02-09 2007-08-23 Hashime Kanazawa Combined pharmaceutical composition
EP1591114A1 (en) * 2004-03-12 2005-11-02 Fournier Laboratories Ireland Limited Use of metformin and orlistat for the treatment or prevention of obesity
US20060286182A1 (en) * 2005-06-21 2006-12-21 Abeille Pharmaceuticals, Inc. Synergistic cinnamon combinations and methods for enhancing insulin activity
GB0602639D0 (en) * 2006-02-09 2006-03-22 Novartis Ag Organic compounds
WO2008015763A1 (fr) 2006-08-04 2008-02-07 Aska Pharmaceutical Co., Ltd. Formulation médicamenteuse contenant un médicament fibrate et procédé pour la produire
CN101342164B (zh) * 2007-08-21 2011-04-20 阜新市仙鹤制药有限责任公司 苯扎贝特控释制剂及其制备方法
US11304960B2 (en) 2009-01-08 2022-04-19 Chandrashekar Giliyar Steroidal compositions
US9339458B2 (en) * 2009-02-18 2016-05-17 Itf Research Pharma, S.L.U. Use of vaginal insulin sensitizing agents
ES2344183B1 (es) * 2009-02-18 2011-06-10 Italfarmaco, S.A. Uso de agentes sensibilizantes a insulina por via vaginal.
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US9358241B2 (en) 2010-11-30 2016-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US20180153904A1 (en) 2010-11-30 2018-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US20120148675A1 (en) 2010-12-10 2012-06-14 Basawaraj Chickmath Testosterone undecanoate compositions
JP2012171911A (ja) 2011-02-22 2012-09-10 Kao Corp Ｐｐａｒ活性化剤
US9382187B2 (en) * 2012-07-10 2016-07-05 Thetis Pharmaceuticals Llc Tri-salt form of metformin
CN104684889A (zh) * 2012-07-10 2015-06-03 西蒂斯制药有限责任公司 二甲双胍的三盐形式
US8765811B2 (en) * 2012-07-10 2014-07-01 Thetis Pharmaceuticals Llc Tri-salt form of metformin
CA2947741A1 (en) 2014-05-05 2015-11-12 Thetis Pharmaceuticals Llc Compositions and methods relating to ionic salts of peptides
WO2015183794A1 (en) 2014-05-27 2015-12-03 City Of Hope Tgr5 agonist complexes for treating diabetes and cancer
US9242008B2 (en) 2014-06-18 2016-01-26 Thetis Pharmaceuticals Llc Mineral amino-acid complexes of fatty acids
US9999626B2 (en) 2014-06-18 2018-06-19 Thetis Pharmaceuticals Llc Mineral amino-acid complexes of active agents
US9498485B2 (en) 2014-08-28 2016-11-22 Lipocine Inc. Bioavailable solid state (17-β)-hydroxy-4-androsten-3-one esters
WO2016033549A2 (en) 2014-08-28 2016-03-03 Lipocine Inc. (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE
US20160361322A1 (en) 2015-06-15 2016-12-15 Lipocine Inc. Composition and method for oral delivery of androgen prodrugs
FR3050112B1 (fr) * 2016-04-15 2020-09-04 Soc Civ Immobiliere Gecinq Utilisation de l'acide fenofibrique dans le traitement des maladies hepatiques
ES2827796T3 (es) 2016-06-03 2021-05-24 Thetis Pharmaceuticals Llc Composiciones y procedimientos relativos a sales de mediadores pro-resolutivos especializados de inflamación
US10344002B2 (en) 2016-09-26 2019-07-09 Nusirt Sciences, Inc. Compositions and methods for treating metabolic disorders
FR3056908B1 (fr) * 2016-09-30 2019-04-19 Nashpharm Sel de metformine et d'elafibranor presentant une activite duale pour le traitement de l'obesite associee a la steato-hepatite non alcoolique (nash) et a l'hypertriglyceridemie
US11559530B2 (en) 2016-11-28 2023-01-24 Lipocine Inc. Oral testosterone undecanoate therapy
WO2020018974A1 (en) 2018-07-20 2020-01-23 Lipocine Inc. Liver disease
GB2599950A (en) * 2020-10-16 2022-04-20 Zentiva Ks Pharmaceutical compositions with low amounts of nitrosamine impurities and methods for producing the same
WO2023119100A1 (en) * 2021-12-22 2023-06-29 Mankind Pharma Ltd. Stable pharmaceutical compositions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4080472A (en) 1974-03-22 1978-03-21 Societe D'etudes Et D'exploitation De Marques Et Brevets S.E.M.S. Metformin 2-(p-chlorophenoxy)-2-methylpropionate
FR2264525B1 (no) * 1974-03-22 1977-11-04 Expl Marques Brevets Et
DE3729209A1 (de) * 1987-09-01 1989-03-09 Boehringer Mannheim Gmbh Verwendung von bezafibrat zur behandlung von diabetes
ZA918168B (en) * 1990-10-16 1993-04-14 Takeda Chemical Industries Ltd Prolonged release preparation and polymers thereof.
JP3852621B2 (ja) * 1992-01-21 2006-12-06 あすか製薬株式会社 血管内皮細胞機能改善剤
AU4050797A (en) * 1996-08-02 1998-02-25 Ligand Pharmaceuticals Incorporated Prevention or treatment of type 2 diabetes or cardiovascular disease with ppar modulators

Also Published As

Publication number Publication date
CZ20002828A3 (cs) 2000-11-15
ID26254A (id) 2000-12-07
BRPI9907866B1 (pt) 2017-08-15
HK1034913A1 (en) 2001-11-09
RU2207850C2 (ru) 2003-07-10
MY118164A (en) 2004-09-30
CN1290160A (zh) 2001-04-04
DE69900249T2 (de) 2002-06-13
TW518222B (en) 2003-01-21
UA70315C2 (en) 2004-10-15
US6372790B1 (en) 2002-04-16
WO1999040904A3 (en) 1999-09-30
BR9907866A (pt) 2000-10-31
WO1999040904A2 (en) 1999-08-19
PT1054665E (pt) 2002-02-28
JP4767411B2 (ja) 2011-09-07
FR2774591B1 (fr) 2000-05-05
CZ290101B6 (cs) 2002-05-15
PL196874B1 (pl) 2008-02-29
CN1151785C (zh) 2004-06-02
DK1054665T3 (da) 2001-12-27
ZA991077B (en) 1999-08-11
CA2320039C (en) 2008-07-22
AR018286A1 (es) 2001-11-14
HUP0100801A3 (en) 2001-12-28
SK11562000A3 (sk) 2000-12-11
ATE204754T1 (de) 2001-09-15
EP1054665B1 (en) 2001-08-29
AU746821B2 (en) 2002-05-02
BRPI9907866B8 (pt) 2021-05-25
AU2923399A (en) 1999-08-30
JP2002502869A (ja) 2002-01-29
DE69900249D1 (de) 2001-10-04
ES2162517T3 (es) 2001-12-16
NO20004056D0 (no) 2000-08-11
NO328314B1 (no) 2010-01-25
HUP0100801A2 (hu) 2001-08-28
KR20010040925A (ko) 2001-05-15
FR2774591A1 (fr) 1999-08-13
SK283212B6 (sk) 2003-03-04
CA2320039A1 (en) 1999-08-19
HU224619B1 (hu) 2005-11-28
KR100567608B1 (ko) 2006-04-04
EP1054665A2 (en) 2000-11-29
PL342665A1 (en) 2001-07-02

Similar Documents

Publication Publication Date Title
NO20004056L (no) Farmasøytisk preparat som omfatter en kombinasjon av metformin og fibrat, og dets anvendelse til fremstilling av medisiner beregnet til Õ redusere hyperglykemi
ZA200203368B (en) Pharmaceutical composition comprising a combination of metformin and glibenclamide.
ATE309206T1 (de) Schwefel-substituierte sulfonylaminocarbonsäure n-arylamide, ihre herstellung, ihre anwendung und diese enthaltende pharmazeutische zusammensetzungen
NO20006138L (no) Substituerte indolinoner, fremstilling og anvendelse derav som medikamenter
NO20012245D0 (no) Anthranilsyreamider og anvendelse derav som medikamenter
ID27757A (id) Indolinona-indolinona tersubstitusi baru, preparasi dan penggunaannya sebagai obat
DK0814840T3 (da) Orale farmaceutiske doseringsformer, der omfatter en protonpumpeinhibitor og et prokinetisk middel
IS5665A (is) Lyfjafræðileg þrýstiúða samsetning
ID26420A (id) Indolinon-indolinon tersubstitusi baru, pembuatannya dan penggunaannya sebagai komposisi-komposisi farmasi
IS5526A (is) 11ß-Halógen-7alfa-setin estratríen, aðferð til framleiðslu á lyfjasamsetningum sem innihalda fyrrnefnd estratríen og notkun þeirra til framleiðslu á læknislyfjum
ID21115A (id) Isokuinolin-3-karboksamida tersubstitusi, pembuatannya serta penggunaannya sebagai obat
IS4394A (is) Meðferðaefnasambönd, lyfjafræðilega hæf sölt og samsetningar sem innihalda efnasamböndin, ásamt notkun þeirra
CA2222676A1 (en) New pharmaceutical composition with anaesthetic effect
DK1033990T3 (da) 21-Hydroxy-6,19-oxidoprogesteron (21OH-6OP) dets anvendelse som medikament i behandling af glucocorticoidoverskud
AU2003292239A8 (en) Novel carboxamides, the production and use thereof as medicaments
NO20005990D0 (no) Platinumkompleks, dets fremstilling og terapeutiske anvendelse
NO20005146D0 (no) Tienylazolylalkoksyetanaminer, deres fremstilling og deres anvendelse som medikamenter
IL149139A0 (en) Pharmaceutical compositions containing metformin and glyburide
HUP0400988A3 (en) Use of compounds with combined nep/mp-inhibitory activity in the preparation of medicaments
IS6378A (is) Efnasambönd og samsetningar gegn dvergveirum, notkun þeirra til lyfjagerðar og efni til að framleiða þau
NO20042158L (no) Substituert 4-fenyl-tetrahydroisokinoliner, fremgangsmate for fremstilling derav, anvendelse derav som medikamenter, i tillegg til medikamenter inneholdende samme
EE200200342A (et) Asendatud 8-arüülkinoliinid, nende kasutamine, farmatseutiline kompositsioon ja prekursorühend
ID20855A (id) Senyawa turunan imidazolidin baru, pembuatannya, penggunaannya dan sediaan farmasi yang mengandung senyawa tersebut
IL167187A (en) Composition comprising modafinil, said composition for use as a medicament and use of said composition for the preparation of medicament
IT1306133B1 (it) Composizione comprendente una carnitina ed un inositolfosfato, utilequale integratore dietetico o medicamento.

Legal Events

Date Code Title Description
MK1K Patent expired