NO20004056L - Farmasøytisk preparat som omfatter en kombinasjon av metformin og fibrat, og dets anvendelse til fremstilling av medisiner beregnet til Õ redusere hyperglykemi - Google Patents

Farmasøytisk preparat som omfatter en kombinasjon av metformin og fibrat, og dets anvendelse til fremstilling av medisiner beregnet til Õ redusere hyperglykemi

Info

Publication number
NO20004056L
NO20004056L NO20004056A NO20004056A NO20004056L NO 20004056 L NO20004056 L NO 20004056L NO 20004056 A NO20004056 A NO 20004056A NO 20004056 A NO20004056 A NO 20004056A NO 20004056 L NO20004056 L NO 20004056L
Authority
NO
Norway
Prior art keywords
fibrate
metformin
manufacture
combination
pharmaceutical composition
Prior art date
Application number
NO20004056A
Other languages
English (en)
Other versions
NO328314B1 (no
NO20004056D0 (no
Inventor
Yves Bonhomme
Philippe Briet
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of NO20004056D0 publication Critical patent/NO20004056D0/no
Publication of NO20004056L publication Critical patent/NO20004056L/no
Publication of NO328314B1 publication Critical patent/NO328314B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO20004056A 1998-02-12 2000-08-11 Farmasoytisk preparat som omfatter en kombinasjon av metformin og fibrat, og dets anvendelse til fremstilling av medisiner beregnet til a redusere hyperglykemi NO328314B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9801709A FR2774591B1 (fr) 1998-02-12 1998-02-12 Composition pharmaceutique comprenant l'association metformine et fibrate et son utilisation pour la preparation de medicaments destines a reduire l'hyperglycemie
PCT/EP1999/000614 WO1999040904A2 (en) 1998-02-12 1999-01-30 Pharmaceutical composition comprising a combination of metformin and fibrate, and its use for the treatment of hyperglycemia

Publications (3)

Publication Number Publication Date
NO20004056D0 NO20004056D0 (no) 2000-08-11
NO20004056L true NO20004056L (no) 2000-08-11
NO328314B1 NO328314B1 (no) 2010-01-25

Family

ID=9522912

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20004056A NO328314B1 (no) 1998-02-12 2000-08-11 Farmasoytisk preparat som omfatter en kombinasjon av metformin og fibrat, og dets anvendelse til fremstilling av medisiner beregnet til a redusere hyperglykemi

Country Status (27)

Country Link
US (1) US6372790B1 (no)
EP (1) EP1054665B1 (no)
JP (1) JP4767411B2 (no)
KR (1) KR100567608B1 (no)
CN (1) CN1151785C (no)
AR (1) AR018286A1 (no)
AT (1) ATE204754T1 (no)
AU (1) AU746821B2 (no)
BR (1) BRPI9907866B8 (no)
CA (1) CA2320039C (no)
CZ (1) CZ290101B6 (no)
DE (1) DE69900249T2 (no)
DK (1) DK1054665T3 (no)
ES (1) ES2162517T3 (no)
FR (1) FR2774591B1 (no)
HU (1) HU224619B1 (no)
ID (1) ID26254A (no)
MY (1) MY118164A (no)
NO (1) NO328314B1 (no)
PL (1) PL196874B1 (no)
PT (1) PT1054665E (no)
RU (1) RU2207850C2 (no)
SK (1) SK283212B6 (no)
TW (1) TW518222B (no)
UA (1) UA70315C2 (no)
WO (1) WO1999040904A2 (no)
ZA (1) ZA991077B (no)

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US6586438B2 (en) 1999-11-03 2003-07-01 Bristol-Myers Squibb Co. Antidiabetic formulation and method
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US6531158B1 (en) * 2000-08-09 2003-03-11 Impax Laboratories, Inc. Drug delivery system for enhanced bioavailability of hydrophobic active ingredients
JP4829411B2 (ja) * 2001-02-23 2011-12-07 キッセイ薬品工業株式会社 Ｃ型慢性肝炎治療剤
GB0119480D0 (en) 2001-08-09 2001-10-03 Jagotec Ag Novel compositions
WO2003105809A1 (en) 2002-06-17 2003-12-24 Themis Laboratories Private Limited Multilayer tablets containing thiazolidinedione and biguanides and methods for producing them
EP1424070A1 (en) * 2002-11-28 2004-06-02 Fournier Laboratories Ireland Limited Combination of a PPAR alpha agonist and metformin for decreasing the serum triglycerides
JP2006511525A (ja) 2002-12-13 2006-04-06 ヤゴテック アーゲー ナノ粒子状スピロノラクトン局所製剤
RU2358738C2 (ru) * 2003-02-07 2009-06-20 Адзиномото Ко., Инк. Лекарственные средства для лечения сахарного диабета
FR2851734B1 (fr) * 2003-02-28 2006-06-09 Galenix Innovations Procede pour la fabrication d'une composition pharmaceutique sous la forme de comprimes contenant un fibrate et comprimes obtenus selon le procede
FR2858556B1 (fr) * 2003-08-06 2006-03-10 Galenix Innovations Composition pharmaceutique solide dispersible et/ou orodispersible non pelliculee contenant au moins le principe actif metformine, et procede de preparation
RU2241449C1 (ru) * 2003-09-25 2004-12-10 Открытое акционерное общество "Химико-фармацевтический комбинат "Акрихин" Фармацевтическая композиция для лечения диабета (варианты)
US8062664B2 (en) * 2003-11-12 2011-11-22 Abbott Laboratories Process for preparing formulations of lipid-regulating drugs
RU2367423C2 (ru) 2003-12-19 2009-09-20 ОМЕГА БИО-ФАРМА (Ай.Пи. 3) ЛИМИТЕД Композиции и способы для лечения диабета
EP1559419A1 (en) * 2004-01-23 2005-08-03 Fournier Laboratories Ireland Limited Pharmaceutical formulations comprising metformin and a fibrate, and processes for their obtention
US20070197602A1 (en) * 2004-02-09 2007-08-23 Hashime Kanazawa Combined pharmaceutical composition
EP1591114A1 (en) * 2004-03-12 2005-11-02 Fournier Laboratories Ireland Limited Use of metformin and orlistat for the treatment or prevention of obesity
US20060286182A1 (en) * 2005-06-21 2006-12-21 Abeille Pharmaceuticals, Inc. Synergistic cinnamon combinations and methods for enhancing insulin activity
GB0602639D0 (en) * 2006-02-09 2006-03-22 Novartis Ag Organic compounds
WO2008015763A1 (fr) 2006-08-04 2008-02-07 Aska Pharmaceutical Co., Ltd. Formulation médicamenteuse contenant un médicament fibrate et procédé pour la produire
CN101342164B (zh) * 2007-08-21 2011-04-20 阜新市仙鹤制药有限责任公司 苯扎贝特控释制剂及其制备方法
US11304960B2 (en) 2009-01-08 2022-04-19 Chandrashekar Giliyar Steroidal compositions
ES2344183B1 (es) * 2009-02-18 2011-06-10 Italfarmaco, S.A. Uso de agentes sensibilizantes a insulina por via vaginal.
US9339458B2 (en) * 2009-02-18 2016-05-17 Itf Research Pharma, S.L.U. Use of vaginal insulin sensitizing agents
US20180153904A1 (en) 2010-11-30 2018-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US9358241B2 (en) 2010-11-30 2016-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US20120148675A1 (en) 2010-12-10 2012-06-14 Basawaraj Chickmath Testosterone undecanoate compositions
JP2012171911A (ja) 2011-02-22 2012-09-10 Kao Corp Ｐｐａｒ活性化剤
EP2872483A4 (en) * 2012-07-10 2016-03-16 Thetis Pharmaceuticals Llc THREE METFORMIN SALT FORM
US8765811B2 (en) * 2012-07-10 2014-07-01 Thetis Pharmaceuticals Llc Tri-salt form of metformin
US9382187B2 (en) * 2012-07-10 2016-07-05 Thetis Pharmaceuticals Llc Tri-salt form of metformin
WO2015171516A1 (en) 2014-05-05 2015-11-12 Thetis Pharmaceuticals Llc Compositions and methods relating to ionic salts of peptides
WO2015183794A1 (en) 2014-05-27 2015-12-03 City Of Hope Tgr5 agonist complexes for treating diabetes and cancer
CN107074884A (zh) 2014-06-18 2017-08-18 西蒂斯制药有限责任公司 活性剂的矿物质氨基酸复合物
US9242008B2 (en) 2014-06-18 2016-01-26 Thetis Pharmaceuticals Llc Mineral amino-acid complexes of fatty acids
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US9498485B2 (en) 2014-08-28 2016-11-22 Lipocine Inc. Bioavailable solid state (17-β)-hydroxy-4-androsten-3-one esters
US20160361322A1 (en) 2015-06-15 2016-12-15 Lipocine Inc. Composition and method for oral delivery of androgen prodrugs
FR3050112B1 (fr) * 2016-04-15 2020-09-04 Soc Civ Immobiliere Gecinq Utilisation de l'acide fenofibrique dans le traitement des maladies hepatiques
JP6906047B2 (ja) 2016-06-03 2021-07-21 テティス・ファーマシューティカルズ・エルエルシー 特異的炎症収束性メディエーターの塩に関連する組成物及び方法
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US11559530B2 (en) 2016-11-28 2023-01-24 Lipocine Inc. Oral testosterone undecanoate therapy
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GB2599950A (en) * 2020-10-16 2022-04-20 Zentiva Ks Pharmaceutical compositions with low amounts of nitrosamine impurities and methods for producing the same
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FR2264525B1 (no) * 1974-03-22 1977-11-04 Expl Marques Brevets Et
US4080472A (en) 1974-03-22 1978-03-21 Societe D'etudes Et D'exploitation De Marques Et Brevets S.E.M.S. Metformin 2-(p-chlorophenoxy)-2-methylpropionate
DE3729209A1 (de) * 1987-09-01 1989-03-09 Boehringer Mannheim Gmbh Verwendung von bezafibrat zur behandlung von diabetes
NZ240214A (en) * 1990-10-16 1993-02-25 Takeda Chemical Industries Ltd Polymer compositions comprising a polylactic acid and a copolymer of glycolic acid and a hydroxycarboxylic acid; use as carrier for prolonged release pharmaceutical compositions of water soluble drugs
JP3852621B2 (ja) * 1992-01-21 2006-12-06 あすか製薬株式会社 血管内皮細胞機能改善剤
WO1998005331A2 (en) * 1996-08-02 1998-02-12 Ligand Pharmaceuticals Incorporated Prevention or treatment of type 2 diabetes or cardiovascular disease with ppar modulators

Also Published As

Publication number Publication date
DE69900249D1 (de) 2001-10-04
CA2320039C (en) 2008-07-22
ES2162517T3 (es) 2001-12-16
KR20010040925A (ko) 2001-05-15
BR9907866A (pt) 2000-10-31
ZA991077B (en) 1999-08-11
BRPI9907866B8 (pt) 2021-05-25
NO328314B1 (no) 2010-01-25
NO20004056D0 (no) 2000-08-11
CZ290101B6 (cs) 2002-05-15
MY118164A (en) 2004-09-30
EP1054665A2 (en) 2000-11-29
PL196874B1 (pl) 2008-02-29
ATE204754T1 (de) 2001-09-15
CN1290160A (zh) 2001-04-04
FR2774591A1 (fr) 1999-08-13
JP4767411B2 (ja) 2011-09-07
BRPI9907866B1 (pt) 2017-08-15
CA2320039A1 (en) 1999-08-19
HUP0100801A2 (hu) 2001-08-28
RU2207850C2 (ru) 2003-07-10
FR2774591B1 (fr) 2000-05-05
EP1054665B1 (en) 2001-08-29
KR100567608B1 (ko) 2006-04-04
AU746821B2 (en) 2002-05-02
PL342665A1 (en) 2001-07-02
ID26254A (id) 2000-12-07
HK1034913A1 (en) 2001-11-09
WO1999040904A2 (en) 1999-08-19
TW518222B (en) 2003-01-21
DK1054665T3 (da) 2001-12-27
PT1054665E (pt) 2002-02-28
CZ20002828A3 (cs) 2000-11-15
HU224619B1 (hu) 2005-11-28
SK11562000A3 (sk) 2000-12-11
SK283212B6 (sk) 2003-03-04
AR018286A1 (es) 2001-11-14
DE69900249T2 (de) 2002-06-13
CN1151785C (zh) 2004-06-02
HUP0100801A3 (en) 2001-12-28
UA70315C2 (en) 2004-10-15
US6372790B1 (en) 2002-04-16
WO1999040904A3 (en) 1999-09-30
AU2923399A (en) 1999-08-30
JP2002502869A (ja) 2002-01-29

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