NO20004679L - Farmasøytisk sammensetning inneholdende en cystein- proteasehemmer for forebygging og terapi av hjernevevsforringelse - Google Patents
Farmasøytisk sammensetning inneholdende en cystein- proteasehemmer for forebygging og terapi av hjernevevsforringelseInfo
- Publication number
- NO20004679L NO20004679L NO20004679A NO20004679A NO20004679L NO 20004679 L NO20004679 L NO 20004679L NO 20004679 A NO20004679 A NO 20004679A NO 20004679 A NO20004679 A NO 20004679A NO 20004679 L NO20004679 L NO 20004679L
- Authority
- NO
- Norway
- Prior art keywords
- therapy
- pharmaceutical composition
- carbon atoms
- prevention
- composition containing
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 238000002560 therapeutic procedure Methods 0.000 title abstract 2
- 101000749287 Clitocybe nebularis Clitocypin Proteins 0.000 title 1
- 101000767029 Clitocybe nebularis Clitocypin-1 Proteins 0.000 title 1
- 229940094664 Cysteine protease inhibitor Drugs 0.000 title 1
- 210000005013 brain tissue Anatomy 0.000 title 1
- 230000006866 deterioration Effects 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000006615 aromatic heterocyclic group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000008354 tissue degradation Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Indole Compounds (AREA)
- Peptides Or Proteins (AREA)
Abstract
En farmasøytisk sammensetning for profylakse og terapi av hjemevevsforringelse, som inneholder, som en aktiv ingrediens, en forbindelse med formel (I) der R1 står for en alkylgruppe med 1-4 karbonatomer eller en arylgmppe med 6-10 karbonatomer som eventuelt er substituert; R2 og R3 kan være like eller forskjellige og hver står for hydrogen eller en alkylgruppe med l -4 karbonatomer, eller R2 og R3 kan sammen danne en ring med 3-7 karbonatomer; og R4 står for en lavere alkylgruppe som eventuelt er substituert med aryl, cykloalkyl, eller en aromatisk heterocyklisk rest, eller et farmasøytisk akseptabelt salt derav.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7228098 | 1998-03-20 | ||
| PCT/JP1999/001335 WO1999048522A1 (en) | 1998-03-20 | 1999-03-17 | Pharmaceutical composition containing a cysteine protease inhibitor for prophylaxis and therapy of brain tissue impairment |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20004679D0 NO20004679D0 (no) | 2000-09-19 |
| NO20004679L true NO20004679L (no) | 2000-10-26 |
Family
ID=13484725
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20004679A NO20004679L (no) | 1998-03-20 | 2000-09-19 | Farmasøytisk sammensetning inneholdende en cystein- proteasehemmer for forebygging og terapi av hjernevevsforringelse |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6342531B1 (no) |
| EP (1) | EP1064021B1 (no) |
| JP (1) | JP2002507579A (no) |
| KR (1) | KR20010041967A (no) |
| CN (1) | CN1301173A (no) |
| AR (1) | AR018784A1 (no) |
| AT (1) | ATE275420T1 (no) |
| AU (1) | AU2852699A (no) |
| BR (1) | BR9908948A (no) |
| CA (1) | CA2324566A1 (no) |
| DE (1) | DE69919995T2 (no) |
| ES (1) | ES2224613T3 (no) |
| HU (1) | HUP0101428A2 (no) |
| ID (1) | ID27507A (no) |
| MX (1) | MXPA00009188A (no) |
| MY (1) | MY133063A (no) |
| NO (1) | NO20004679L (no) |
| PL (1) | PL342970A1 (no) |
| WO (1) | WO1999048522A1 (no) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001024781A2 (en) * | 1999-10-07 | 2001-04-12 | Novaneuron Inc. | Gene necessary for striatal function, uses thereof, and compounds for modulating same |
| EP1334718A4 (en) | 2000-10-26 | 2007-07-18 | Senju Pharma Co | DRUG COMPOSITION CONTAINING DIPEPTIDYL ALDEHYDE COMPOUND |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992011850A2 (en) * | 1990-12-28 | 1992-07-23 | Cortex Pharmaceuticals, Inc. | Use of calpain inhibitors in the inhibition and treatment of neurodegeneration |
| ES2190139T3 (es) | 1995-10-25 | 2003-07-16 | Senju Pharma Co | Inhibidor de la angiogenesis. |
-
1999
- 1999-03-17 US US09/646,529 patent/US6342531B1/en not_active Expired - Fee Related
- 1999-03-17 BR BR9908948-3A patent/BR9908948A/pt not_active Application Discontinuation
- 1999-03-17 AT AT99909212T patent/ATE275420T1/de not_active IP Right Cessation
- 1999-03-17 CN CN99806167A patent/CN1301173A/zh active Pending
- 1999-03-17 MX MXPA00009188A patent/MXPA00009188A/es unknown
- 1999-03-17 WO PCT/JP1999/001335 patent/WO1999048522A1/en not_active Ceased
- 1999-03-17 EP EP99909212A patent/EP1064021B1/en not_active Expired - Lifetime
- 1999-03-17 AU AU28526/99A patent/AU2852699A/en not_active Abandoned
- 1999-03-17 PL PL99342970A patent/PL342970A1/xx not_active Application Discontinuation
- 1999-03-17 ES ES99909212T patent/ES2224613T3/es not_active Expired - Lifetime
- 1999-03-17 DE DE69919995T patent/DE69919995T2/de not_active Expired - Lifetime
- 1999-03-17 JP JP2000537569A patent/JP2002507579A/ja not_active Ceased
- 1999-03-17 CA CA002324566A patent/CA2324566A1/en not_active Abandoned
- 1999-03-17 HU HU0101428A patent/HUP0101428A2/hu unknown
- 1999-03-17 ID IDW20002104A patent/ID27507A/id unknown
- 1999-03-17 MY MYPI99000998A patent/MY133063A/en unknown
- 1999-03-17 KR KR1020007010291A patent/KR20010041967A/ko not_active Withdrawn
- 1999-03-19 AR ARP990101215A patent/AR018784A1/es unknown
-
2000
- 2000-09-19 NO NO20004679A patent/NO20004679L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| PL342970A1 (en) | 2001-07-16 |
| ID27507A (id) | 2001-04-12 |
| DE69919995D1 (de) | 2004-10-14 |
| ATE275420T1 (de) | 2004-09-15 |
| BR9908948A (pt) | 2000-11-21 |
| CA2324566A1 (en) | 1999-09-30 |
| CN1301173A (zh) | 2001-06-27 |
| EP1064021B1 (en) | 2004-09-08 |
| US6342531B1 (en) | 2002-01-29 |
| DE69919995T2 (de) | 2005-09-22 |
| KR20010041967A (ko) | 2001-05-25 |
| JP2002507579A (ja) | 2002-03-12 |
| WO1999048522A1 (en) | 1999-09-30 |
| ES2224613T3 (es) | 2005-03-01 |
| HUP0101428A2 (hu) | 2001-09-28 |
| AU2852699A (en) | 1999-10-18 |
| AR018784A1 (es) | 2001-12-12 |
| EP1064021A1 (en) | 2001-01-03 |
| MXPA00009188A (es) | 2002-04-24 |
| NO20004679D0 (no) | 2000-09-19 |
| MY133063A (en) | 2007-10-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |